10 Medicinal Constituents Of Tanacetum Parthenium (Feverfew)

Tanacetum parthenium has active constituents such as sesquiterpene lactones, flavonoids, and caffeic acid derivatives.

These constituents confer anti-inflammatory, anti-migraine, and antioxidant properties, which are beneficial in reducing pain and inflammation, as well as preventing and alleviating symptoms of migraines and other headaches.

For example, patients with frequent migraines have reported reduced frequency and severity of episodes after consuming feverfew tea or capsules, allowing them to enjoy improved quality of life and reduced reliance on medication.

This article explains in details the 10 best active constituents of Tanacetum parthenium.

1. Sesquiterpenes

Tanacetum parthenium sesquiterpenes is a type of compound found in its leaves and flowers.

These sesquiterpenes have been shown to exhibit anti-inflammatory and antioxidant properties, making them useful for treating various health issues such as arthritis, migraines, and skin conditions.

They are also believed to have antimicrobial and antiviral effects, further highlighting their potential therapeutic applications.

2. Flavonoids

3. Coumarins

Tanacetum parthenium coumarins is a type of lignan that is found in the plant.

These compounds have been shown to possess anticoagulant and anti-inflammatory properties, making them potentially useful for treating various health conditions such as arthritis and cardiovascular disease.

Coumarins are also responsible for feverfew's bitter taste and have been traditionally used to treat headaches, particularly migraines.

4. Phenolic acids

Tanacetum parthenium phenolic acids is a class of compounds responsible for its medicinal properties.

These acidic derivatives of polyphenols are abundant in the plant's aerial parts and have been shown to possess anti-inflammatory, antioxidant, and antimicrobial activities.

The most prominent phenolic acids found in feverfew include chlorogenic acid, caffeic acid, and rosmarinic acid, which contribute to its therapeutic potential in treating various diseases such as headaches, arthritis, and allergies.

5. Lignans

Tanacetum parthenium lignans is a class of phenolic compounds found in its leaves.

These lignans have been shown to exhibit various biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties.

They have also been found to inhibit the activity of certain enzymes involved in inflammation and may help to protect against chronic diseases such as cardiovascular disease and cancer.

6. Sesquiterpene lactones

Tanacetum parthenium sesquiterpene lactones is a group of bioactive compounds responsible for the medicinal properties of this plant.

These compounds have been shown to exhibit anti-inflammatory, antipyretic, and analgesic effects, making them valuable in the treatment of various health conditions such as arthritis, headaches, and fever.

Additionally, they also possess antioxidant and antimicrobial activities, further solidifying their importance in traditional medicine.

7. Oleic acid

Tanacetum parthenium oleic acid is a primary active compound responsible for its medicinal properties.

This essential fatty acid has been extensively studied for its anti-inflammatory and antioxidant effects.

Oleic acid in feverfew is believed to contribute to its analgesic and antipyretic activities, making it a valuable component in traditional medicine for treating various conditions such as headaches, arthritis, and fever.

8. Linoleic acid

Tanacetum parthenium linoleic acid is an essential fatty acid found in its leaves.

It has been shown to have potent anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products and supplements. Linoleic acid has been studied for its potential benefits in reducing inflammation, improving skin elasticity, and promoting wound healing, among other applications.

Its incorporation into Tanacetum parthenium may contribute to the plant's traditional uses in herbal medicine.

9. Palmitic acid

Tanacetum parthenium palmitic acid is a primary constituent of its leaves.

It is an omega-7 fatty acid, which is typically found in small amounts in various plant species. Palmitoleic acid has been shown to possess potent anti-inflammatory and antioxidant properties, making it beneficial for the treatment of various skin conditions and diseases.

Additionally, it may help to reduce inflammation and oxidative stress in the body.

10. Caffeic acid

Tanacetum parthenium caffeic acid is a phenolic compound that has been isolated from its leaves.

Caffeic acid is responsible for many of the plant's medicinal properties, including anti-inflammatory and antipyretic effects.

It has also been shown to have antioxidant and antimicrobial activities, making it a valuable component in traditional medicine.