feverfew
Tanacetum parthenium · Accepted scientific name
Scientific literature: Very Extensive (1560 studies) · ★★★★★
Feverfew, scientifically known as Tanacetum parthenium, is a perennial flowering herb renowned for its potent medicinal properties. Traditionally used in herbalism, it is most widely recognized for its ability to prevent migraines and reduce inflammation. This versatile plant remains a cornerstone in natural remedies for supporting vascular health.
Names
Common Names
- feather-leaved tansy
- featherfew
- feverfew
Regional and Traditional Names
Spanish:
- Cochitzapotl
- Madrehuela doble
- Flor de la calentura
- Santa María blanca
- Hierba de altamira
- Parthenium matricaria
- Madrehuela rosea
- Pyrethrum sevanense
- Magarza amarilla
- Chapote
- Leucanthemum odoratum
- Artemiza
- Pyrethrum demetrii
- Santa maría
- Gamaza
- Flor de santos
- Santa Maria blanca
- Santa maria
- altamisa
- Artemisa
- Santa María
German:
- Mutterkraut
- Zierkamille
- Fieberkraut
- Chrysanthemum parthenium
- grande camomille
- Mutterkraut
- Falsche Kamille
- Mutterkraut-Wucherblume
French:
- Pyrèthre doré
- Grande Camomille
- Partenelle
- chrysanthème matricaire
- grande camomille
- pyrèthre doré
- pyrèthre mousse
- grande camomile
- Tanaisie matricaire
Scientific Names
Accepted name
Tanacetum partheniumSynonyms
- Parthenium matricaria
- Leucanthemum parthenium
- Chamaemelum parthenium
- Leucanthemum parthenium var. flosculosum
- Chrysanthemum parthenium f. flosculosum
- Matricaria mandiana
- Pyrethrum parthenium var. flosculosum
- Pyrethrum parthenium var. multiplex
- Pyrethrum partheniifolium aureum
- Pyrethrum parthenium eximium
- Matricaria odorata
- Pyrethrum glanduliferum
- Pyrethrum grossheimii
- Matricaria parthenium
- Tanacetum glanduliferum
- Dendranthema parthenium
- Leucanthemum parthenium var. flosculosum
- Tanacetum grossheimii
- Matricaria alba
- Matricaria eximia
- Tanacetum parthenium var. flosculosum
- Matricaria florida
- Chrysanthemum parthenium var. discoideum
- Matricaria vulgaris
- Pontia matricaria
- Pyrethrum eximium
- Chrysanthemum parthenium
- Pyrethrum parthenium
Taxonomical Classification
This plant belongs to the kingdom Plantae within the phylum Streptophyta and is classified under the class Equisetopsida and subclass Magnoliidae. It is further organized under the order Asterales and the family Asteraceae. Finally, the species is identified by its genus, Tanacetum.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Asterales | WCVP |
| Family | Asteraceae | WCVP |
| Genus | Tanacetum | WCVP |
Distribution
This plant, known as Tanacetum parthenium, exhibits a specific geographical presence across several regions in Northern Europe. It can be found growing within the natural landscapes of Denmark. The species is also documented throughout the territories of Great Britain and Ireland. Furthermore, its distribution extends to the northern reaches of the continent in Norway. Finally, this medicinal plant is also native to the regions of Sweden.
| Region | Area | Source |
|---|---|---|
| Northern Europe | Denmark | WCVP |
| Northern Europe | Great Britain | WCVP |
| Northern Europe | Ireland | WCVP |
| Northern Europe | Norway | WCVP |
| Northern Europe | Sweden | WCVP |
| Middle Europe | Austria | WCVP |
| Middle Europe | Belgium | WCVP |
| Middle Europe | Czechia-Slovakia | WCVP |
| Middle Europe | Germany | WCVP |
| Middle Europe | Hungary | WCVP |
Plant Parts
This plant, commonly known as feverfew, possesses distinct morphological features that contribute to its medicinal profile. The vibrant, daisy-like flowers serve as the most striking visual element, typically characterized by white ray florets surrounding a yellow center. These blooms are supported by slender, green stalks that extend upward to facilitate pollination. The foliage consists of deeply lobed, aromatic leaves that contain the plant's bioactive compounds. Once the flowering cycle is complete, the plant produces numerous small seeds, which are often dispersed as individual seeds to ensure the continuation of the species in the wild.| Plant Part | Sources | Consensus |
|---|---|---|
| flower | Phytochemistry (and other 4 sources) | ★★☆☆☆ |
| leaf | Phytochemistry (and other 4 sources) | ★★☆☆☆ |
| root | International journal of molecular sciences (and other 2 sources) | ★☆☆☆☆ |
| seed | Phytochemistry (and other 2 sources) | ★☆☆☆☆ |
Chemicals
Tanacetum parthenium has 171 reported phytochemicals identified across 12 scientific publications and several other databases. The most consistently reported chemicals include parthenolide, apigenin, camphor, arachidonic acid, Alantolactone.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| parthenolide | 42 supporting sources | ★★★★★ |
| apigenin | 4 supporting sources | ★★☆☆☆ |
| camphor | 4 supporting sources | ★★☆☆☆ |
| arachidonic acid | 3 supporting sources | ★★☆☆☆ |
| Alantolactone | 2 supporting sources | ★☆☆☆☆ |
| Apigenin 7-glucuronide | 2 supporting sources | ★☆☆☆☆ |
| Artecanin | 2 supporting sources | ★☆☆☆☆ |
| CAMPHENE | 2 supporting sources | ★☆☆☆☆ |
| Canin | 2 supporting sources | ★☆☆☆☆ |
| Chrysanthenyl acetate | 2 supporting sources | ★☆☆☆☆ |
parthenolide
- Dr. Duke
- Biomedicines
- Behavioural brain research
- Plant cell reports
- Drug discovery today
View 37 additional sources
- Journal of agricultural and food chemistry
- The Journal of pharmacy and pharmacology
- Biochemical and biophysical research communications
- Biochemical pharmacology
- Chemistry & biology
- British journal of clinical pharmacology
- Cellular immunology
- Journal of ethnopharmacology
- Immunology letters
- Oncogene
- Planta medica
- Cell death and differentiation
- Pharmacognosy reviews
- Molecular carcinogenesis
- Journal of medicinal food
- Journal of natural products
- Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
- Acta pharmacologica Sinica
- Plant molecular biology
- Journal of pharmaceutical and biomedical analysis
- Expert opinion on biological therapy
- Metabolic engineering
- Polish journal of pharmacology and pharmacy
- European journal of immunology
- Cell cycle (Georgetown, Tex.)
- Chemosphere
- Drug design, development and therapy
- International journal of molecular sciences
- Phytochemistry
- Contact dermatitis
- Folia haematologica (Leipzig, Germany : 1928)
- Chinese journal of natural medicines
- Plant physiology and biochemistry : PPB
- Molecular medicine reports
- International immunopharmacology
- OncoTargets and therapy
- Acta dermato-venereologica
apigenin
- Molecules (Basel, Switzerland)
- Phytochemistry
- Phytotherapy research : PTR
- Journal of medicinal food
camphor
- Dr. Duke
- International journal of molecular sciences
- Chemistry & biodiversity
- Journal of medicinal food
arachidonic acid
- Biomedica biochimica acta
- Prostaglandins, leukotrienes, and medicine
- The Journal of pharmacy and pharmacology
Alantolactone
- Dr. Duke
- Contact dermatitis
Apigenin 7-glucuronide
- Dr. Duke
- Phytochemistry
Artecanin
- Dr. Duke
- The Journal of pharmacy and pharmacology
CAMPHENE
- Dr. Duke
- International journal of molecular sciences
Canin
- Dr. Duke
- The Journal of pharmacy and pharmacology
Chrysanthenyl acetate
- Dr. Duke
- The Journal of pharmacy and pharmacology
Activities
Tanacetum parthenium has 532 reported activities identified across 12 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antioxidant, Antimigraine, Antibacterial, Antifibrotic.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Anticancer | Dr. Duke (and other 9 sources) | ★★★★☆ |
| Antioxidant | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Antimigraine | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antibacterial | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antifibrotic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antinociceptive | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antispasmodic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antitumor | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Neuroprotective | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| (-)-Chronotropic | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Tanacetum parthenium has 51 reported medicinal uses identified across 12 scientific publications and several other databases. The most consistently reported uses include migraine, cancer, rheumatoid arthritis, arthritis, epilepsy.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| migraine | Italian journal of pediatrics (and other 21 sources) | ★★★★★ |
| cancer | Plant cell reports (and other 5 sources) | ★★★☆☆ |
| rheumatoid arthritis | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists (and other 4 sources) | ★★☆☆☆ |
| arthritis | Biochemical pharmacology (and other 3 sources) | ★★☆☆☆ |
| epilepsy | Biomedicines (and other 3 sources) | ★★☆☆☆ |
| inflammation | Biomedicines (and other 3 sources) | ★★☆☆☆ |
| migraine headaches | Biomedicines (and other 3 sources) | ★★☆☆☆ |
| asthma | Pharmacognosy reviews (and other 2 sources) | ★☆☆☆☆ |
| fever | Biochemical pharmacology (and other 2 sources) | ★☆☆☆☆ |
| fevers | Pharmacognosy reviews (and other 2 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Ethanolic extracts of aerial parts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Extracts of Tanacetum parthenium | Phytotherapy research : PTR (and other 1 sources) | ★☆☆☆☆ |
| Extracts of feverfew | Lancet (London, England) (and other 1 sources) | ★☆☆☆☆ |
| Leaves | Biochemical pharmacology (and other 1 sources) | ★☆☆☆☆ |
| alcoholic and hot water extracts | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (and other 1 sources) | ★☆☆☆☆ |
| aqueous extracts | Polish journal of pharmacology and pharmacy (and other 1 sources) | ★☆☆☆☆ |
| ethanol extracts | Polish journal of pharmacology and pharmacy (and other 1 sources) | ★☆☆☆☆ |
| hydro-alcoholic extract (HAE) | Avicenna journal of phytomedicine (and other 1 sources) | ★☆☆☆☆ |
| infusions | Biochemical pharmacology (and other 1 sources) | ★☆☆☆☆ |
| nutraceutical preparation | Italian journal of pediatrics (and other 1 sources) | ★☆☆☆☆ |