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Updated: Jul 21, 2024

10 Possible Side Effects Of Schisandra Chinensis (Five Flavor Berry)

schisandra chinensis

Schisandra chinensis has some side effects when used improperly, such as digestive issues, allergic reactions, and interactions with medications.

The causes of these side effects can be attributed to excessive consumption, individual sensitivities, and combination with other herbal remedies. For instance, digestive problems can lead to bloating, nausea, and diarrhea, significantly impacting daily life and productivity.

In severe cases, allergic reactions can cause anaphylaxis, which requires immediate medical attention.

This article explains in details the 10 most common side effects of Schisandra chinensis if used imporperly.

1. Interferes with bleeding

Schisandra chinensis increases blood pressure due to its high concentration of anthraquinones and lignans, which can cause vasoconstriction and stimulate the sympathetic nervous system.

This may lead to increased heart rate and blood pressure in some individuals.

Additionally, Schisandra's ability to increase production of cortisol and adrenaline can further contribute to elevated blood pressure levels.

2. Interferes with bleeding

Schisandra chinensis causes allergic reactions in some individuals.

This is due to its unique composition, which includes a high concentration of terpenoids and lignans that can stimulate the immune system and lead to an overactive response.

The allergenic potential of Schisandra chinensis is attributed to its ability to cross-react with other substances, such as pollen or certain foods, triggering an allergic response in susceptible individuals.

3. Interferes with bleeding

Schisandra chinensis provokes digestive upset in some individuals due to its high levels of anthocyanins and other bioactive compounds.

These compounds can stimulate the release of digestive enzymes, leading to increased gut motility and potentially causing stomach discomfort, nausea, or diarrhea.

Additionally, Schisandra's adaptogenic properties may also contribute to this side effect by enhancing the body's natural response to stress, which can disrupt normal digestive functioning.

4. Interferes with bleeding

Schisandra chinensis aggravates kidney stones.

This is due to its high concentration of oxalate, a naturally occurring compound that can increase the risk of stone formation in the kidneys. Additionally, Schisandra chinensis may alter the body's ability to absorb and metabolize calcium, further increasing the likelihood of kidney stone development.

These factors combined may exacerbate existing kidney stone conditions or lead to new formations.

5. Interferes with bleeding

Schisandra chinensis enhances sleepiness by interacting with the brain's neurotransmitters, such as GABA and serotonin.

The herb's active compounds, including schizandrin and gomisin, can increase the activity of these neurotransmitters, leading to a sedative effect. Additionally, Schisandra chinensis may slow down the heart rate and blood pressure, further contributing to feelings of drowsiness.

As a result, individuals using Schisandra chinensis supplements may experience increased sleepiness as a side effect.

6. Interferes with bleeding

Schisandra chinensis reduces appetite.

This is attributed to its adaptogenic properties, which may stimulate the body's natural ability to regulate hunger and satiety hormones, leading to a decrease in appetite. Additionally, Schisandra's bioactive compounds may interact with the brain's reward system, influencing food cravings and intake.

As a result, some individuals may experience reduced appetite when consuming Schisandra chinensis supplements or extracts.

7. Interferes with bleeding

Schisandra chinensis triggers skin rash due to its high concentration of lignans, which can cause allergic reactions in some individuals.

The berries contain a unique combination of bitter, sour, salty, sweet, and umami flavors, which may stimulate the release of histamine, leading to an increase in blood vessels' permeability and subsequent skin irritation.

This reaction is often characterized by itchy or red welts on the skin, and can range from mild to severe depending on individual sensitivity.

8. Interferes with bleeding

Schisandra chinensis induces stomach pain due to its bitter and astringent properties, which can irritate the mucous membranes in the digestive tract.

The high concentration of tannins and lignans in Schisandra chinensis may cause inflammation and constriction of the blood vessels, leading to discomfort and pain in the abdominal region.

Additionally, the berry's ability to slow down digestion may contribute to stomach upset and nausea.

9. Interferes with bleeding

Schisandra chinensis inhibits platelet function by interacting with blood vessels and platelets, reducing the ability of platelets to form clots.

This is due to its high concentration of bioactive compounds such as lignans, phenolic acids, and triterpenes, which can bind to platelet receptors and prevent aggregation.

As a result, individuals using Schisandra chinensis may experience bleeding or bruising more easily, particularly if they are taking anticoagulant medications or have pre-existing bleeding disorders.

10. Interferes with bleeding

Schisandra chinensis affects liver enzymes.

The compound schizandrin in this herb is believed to be responsible for altering liver function and enzyme activity, potentially leading to changes in the body's ability to process medications or metabolize substances.

This effect may be due to schizandrin's ability to inhibit certain liver enzymes involved in detoxification processes.