magnolia-vine

Schisandra chinensis · Accepted scientific name

Scientific literature: Very Extensive (1113 studies) · ★★★★★

Magnolia-vine, scientifically known as Schisandra chinensis, is a versatile woody climber prized in traditional medicine. Often referred to as schisandra, this adaptogen is celebrated for its ability to support stress resilience, enhance mental clarity, and promote liver health. Its unique berry profile offers a complex, revitalizing botanical experience.

Family
Schisandraceae
Native range
Asia-Temperate
Parts used
Fruit · Stem
Common names
Chinese Magnolia-Vine · Five-Flavor-Fruit · 3 more
Scientific synonyms
Maximowiczia Japonica · Maximowiczia Amurensis · 5 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Schisandra chinensis

Synonyms

Regional and Traditional Names

Spanish:

  • Omija

German:

  • Chinesisches Spaltkörbchen
  • Vitalbeere
  • Wu Wei Zi
  • chinesisches Spaltkölbchen

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, placing it within the class Equisetopsida and subclass Magnoliidae. It is further classified under the order Austrobaileyales and the family Schisandraceae. Ultimately, its scientific identity is defined by its placement within the genus Schisandra.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Austrobaileyales
Family Schisandraceae
Genus Schisandra

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant is distributed across several specific regions within the Russian Far East. It can be found growing in the Amur and Khabarovsk territories. Additionally, its natural range extends into the Primorye and Sakhalin regions. Beyond Russia, the species is also located within the Inner Mongolia province of China. Together, these locations define the primary geographical footprint of the species.

Region Area
Russian Far East Amur
Russian Far East Khabarovsk
Russian Far East Primorye
Russian Far East Sakhalin
China Inner Mongolia
China Manchuria
China China North-Central
Eastern Asia Japan
Eastern Asia Korea

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Schisandra chinensis is characterized by its ability to thrive in a diverse range of terrestrial environments, ranging from dense woodlands to more open landscapes. It is frequently found colonizing cut-over forests, established forests, and forest edges, where it can benefit from varying levels of light penetration and structural complexity. This species demonstrates significant ecological plasticity, inhabiting diverse substrates including sandy soils, stony places, and steppe environments. Furthermore, its presence is often associated with riparian zones, as it can be found growing near rivers, suggesting a capacity to manage varying moisture levels within its niche.

Habitat :
cut-over forest, forest, forest edges, rivers, sand, steppe, stony places

Life history

The life history of Schisandra chinensis is characterized by its nature as a perennial woody vine, meaning it lives for many years and maintains its structural presence across multiple growing seasons. As a deciduous climber, it undergoes seasonal cycles of growth, beginning with the emergence of foliage in the spring, followed by the development of small, inconspicuous flowers that facilitate pollination. Following successful fertilization, the plant produces distinctive clusters of bright red berries that mature in late summer or autumn. Because it is a perennial, the plant establishes a robust root system that allows it to endure winter dormancy, storing energy to support vigorous regrowth and continuous reproductive cycles in subsequent years.

Lifecycle :
perennial

Morphology

The morphology of Schisandra chinensis is characterized by its growth habit as a woody liana, functioning as an obligatory climber that utilizes other structures for support rather than being self-supporting. While its growth form can be associated with tree-like structures in certain contexts, it primarily presents as a climbing vine that reaches a maximum plant height of approximately 8 meters. The plant is an independent organism, meaning it does not function as a parasite, and it maintains a terrestrial life cycle rather than being epiphytic. Its structural integrity is defined by its woody nature, providing the necessary strength for its climbing lifestyle.

Climber :
liana
Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
tree
Parasite :
independent
Plant height max:
8 m
Woodiness :
woody

Physiology

The physiology of Schivanra chinensis is characterized by its specialized metabolic and anatomical adaptations suited for life in temperate forest understories. Central to its energy production is its photosynthetic pathway, which functions via the C3 mechanism, utilizing the Calvin cycle to fix atmospheric carbon dioxide. This C3 pathway reflects its ecological niche, as the plant is adapted to environments where moderate light intensity and consistent moisture levels allow for efficient carbon fixation without the water-conserving specialized adaptations found in C4 or CAM plants. Beyond carbon assimilation, the plant exhibits complex secondary metabolic processes, specifically the biosynthesis of lignans such as schisandrin, which are produced as physiological responses to environmental stressors. Its physiological regulation also involves intricate water relations and nutrient uptake mechanisms that support its woody, perennial growth habit and the development of its characteristic fleshy fruit.

Photosynthetic pathway :
C3

Reproduction

The reproduction of Schisandra chinensis is characterized by a specific flowering window and the production of fleshy fruits containing distinct seeds. The flowering period typically begins in May and concludes in June, although the timing can be variable depending on environmental conditions. Following pollination, the plant produces fleshy fruits that house the seeds. These seeds are relatively small and uniform in volume, with a recorded mean, minimum, and maximum seed volume of 10 mm³. In terms of weight, the seeds exhibit slight variations; the mean seed mass is approximately 0.010299 g, with a minimum recorded mass of 0.006878 g and a maximum mass of 0.01372 g.

Flowering time :
May
Flowering time :
Jun
Fruit dryness :
fleshy
Seed mass max:
0.01372 g
Seed mass mean:
0.010299 g
Seed mass min:
0.006878 g
Seed volume max:
10 mm³

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Schisandra chinensis has 5 reported plant parts identified across 43 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, stem, leaf, seed, root.

Plant parts reported in Schisandra chinensis
Plant part Supporting sources Consensus
Fruit 27 supporting sources ★★★★★
Stem 7 supporting sources ★★★★☆
Leaf 4 supporting sources ★★☆☆☆
Seed 3 supporting sources ★★☆☆☆
Root 2 supporting sources ★☆☆☆☆

Fruit

  1. Fitoterapia
  2. Phytotherapy research : PTR
  3. Journal of pharmaceutical and biomedical analysis
  4. Life (Basel, Switzerland)
  5. Journal of agricultural and food chemistry
View 22 additional sources
  1. Journal of cellular and molecular medicine
  2. Frontiers in microbiology
  3. BioMed research international
  4. Journal of microbiology (Seoul, Korea)
  5. International journal of biological macromolecules
  6. Yao xue xue bao = Acta pharmaceutica Sinica
  7. Pharmacology & toxicology
  8. Phytochemistry reviews : proceedings of the Phytochemical Society of Europe
  9. Phytomedicine plus : international journal of phytotherapy and phytopharmacology
  10. Journal of ethnopharmacology
  11. Journal of natural products
  12. Journal of chromatography. A
  13. Phytomedicine : international journal of phytotherapy and phytopharmacology
  14. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
  15. Wiadomosci lekarskie (Warsaw, Poland : 1960)
  16. International journal of molecular sciences
  17. Molecules (Basel, Switzerland)
  18. Phytochemical analysis : PCA
  19. Journal of chromatographic science
  20. Chemistry & biodiversity
  21. Frontiers in plant science
  22. Food science and biotechnology

Stem

  1. Frontiers in microbiology
  2. Biomedical chromatography : BMC
  3. Chinese journal of natural medicines
  4. Journal of ethnopharmacology
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
View 2 additional sources
  1. Evidence-based complementary and alternative medicine : eCAM
  2. Journal of chromatographic science

Leaf

  1. Journal of agricultural and food chemistry
  2. Journal of cellular and molecular medicine
  3. Frontiers in microbiology
  4. Journal of chromatographic science

Seed

  1. The American journal of Chinese medicine
  2. Phytochemical analysis : PCA
  3. Planta medica

Root

  1. Frontiers in microbiology
  2. Fitoterapia

Chemicals

Schisandra chinensis has 220 reported phytochemicals identified across 43 scientific publications and several other databases. The most consistently reported chemicals include Lignans, Schisandrin, Schisandrin B, Gomisin A, Schisandrol A.

Chemicals reported in Schisandra chinensis
Chemical Supporting sources Consensus
Lignans 15 supporting sources ★★★★★
Schisandrin 14 supporting sources ★★★★★
Schisandrin B 11 supporting sources ★★★★★
Gomisin A 10 supporting sources ★★★★★
Schisandrol A 10 supporting sources ★★★★★
Schisantherin A 8 supporting sources ★★★★☆
Gomisin J 7 supporting sources ★★★★☆
Schisandrol B 7 supporting sources ★★★★☆
Schisanhenol 7 supporting sources ★★★★☆
Lignan 6 supporting sources ★★★☆☆

Lignans

  1. Dr. Duke
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  3. Nutrients
  4. Journal of microbiology (Seoul, Korea)
  5. Journal of enzyme inhibition and medicinal chemistry
View 10 additional sources
  1. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti
  2. Frontiers in pharmacology
  3. Chemistry and physics of lipids
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Fitoterapia
  6. International journal of biological macromolecules
  7. Journal of ethnopharmacology
  8. The EPMA journal
  9. Frontiers in nutrition
  10. Biological & pharmaceutical bulletin

Schisandrin

  1. Dr. Duke
  2. BMC genomics
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. Yao xue xue bao = Acta pharmaceutica Sinica
  5. Journal of pharmaceutical and biomedical analysis
View 9 additional sources
  1. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
  2. Journal of ethnopharmacology
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. Journal of chromatography. A
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
  6. Free radical biology & medicine
  7. Chemistry and physics of lipids
  8. Phytochemical analysis : PCA
  9. Applied microbiology and biotechnology

Schisandrin B

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. International journal of molecular sciences
  3. Chinese journal of natural medicines
  4. Journal of microbiology (Seoul, Korea)
  5. Molecules (Basel, Switzerland)
View 6 additional sources
  1. Journal of enzyme inhibition and medicinal chemistry
  2. Journal of chromatography. A
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Free radical biology & medicine
  5. Chemistry and physics of lipids
  6. Chemistry & biodiversity

Gomisin A

  1. Dr. Duke
  2. Nutrients
  3. Fitoterapia
  4. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
  5. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti
View 5 additional sources
  1. Journal of chromatography. A
  2. Journal of separation science
  3. Phytochemical analysis : PCA
  4. Applied microbiology and biotechnology
  5. Research communications in molecular pathology and pharmacology

Schisandrol A

  1. Journal of chromatography. A
  2. Journal of cellular and molecular medicine
  3. Chinese journal of natural medicines
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Plants (Basel, Switzerland)
View 5 additional sources
  1. Journal of enzyme inhibition and medicinal chemistry
  2. Molecules (Basel, Switzerland)
  3. Chinese journal of integrative medicine
  4. Life (Basel, Switzerland)
  5. Biological & pharmaceutical bulletin

Schisantherin A

  1. Dr. Duke
  2. Journal of applied toxicology : JAT
  3. Yao xue xue bao = Acta pharmaceutica Sinica
  4. Journal of ethnopharmacology
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
View 3 additional sources
  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Journal of chromatography. A
  3. Chinese journal of integrative medicine

Gomisin J

  1. Dr. Duke
  2. Fitoterapia
  3. Yao xue xue bao = Acta pharmaceutica Sinica
  4. Molecular medicine reports
  5. Molecules (Basel, Switzerland)
View 2 additional sources
  1. Journal of chromatography. A
  2. Plant physiology and biochemistry : PPB

Schisandrol B

  1. Yao xue xue bao = Acta pharmaceutica Sinica
  2. Chinese journal of natural medicines
  3. Molecules (Basel, Switzerland)
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Journal of enzyme inhibition and medicinal chemistry
View 2 additional sources
  1. Frontiers in plant science
  2. Journal of ethnopharmacology

Schisanhenol

  1. Dr. Duke
  2. Chemico-biological interactions
  3. Acta pharmaceutica Sinica. B
  4. Plants (Basel, Switzerland)
  5. Journal of chromatography. A
View 2 additional sources
  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Plant physiology and biochemistry : PPB

Lignan

  1. Dr. Duke
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology
  3. Life (Basel, Switzerland)
  4. Chinese journal of natural medicines
  5. Yao xue xue bao = Acta pharmaceutica Sinica
View 1 additional sources
  1. Plants (Basel, Switzerland)

Activities

Schisandra chinensis has 428 reported activities identified across 43 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Hepatoprotective, Adaptogenic, Neuroprotective, Sedative.

Activities reported in Schisandra chinensis
Activity Supporting sources Consensus
Antioxidant 8 supporting sources ★★★★☆
Hepatoprotective 6 supporting sources ★★★☆☆
Adaptogenic 5 supporting sources ★★★☆☆
Neuroprotective 4 supporting sources ★★☆☆☆
Sedative 4 supporting sources ★★☆☆☆
Anticancer 3 supporting sources ★★☆☆☆
Cardioprotective 3 supporting sources ★★☆☆☆
Tonic 3 supporting sources ★★☆☆☆
Adaptogen 2 supporting sources ★☆☆☆☆
Antiangiogenic 2 supporting sources ★☆☆☆☆

Antioxidant

  1. Dr. Duke
  2. BMC genomics
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. International journal of biological macromolecules
  5. Journal of ethnopharmacology
View 3 additional sources
  1. Drug design, development and therapy
  2. The EPMA journal
  3. Frontiers in nutrition

Hepatoprotective

  1. Dr. Duke
  2. International journal of molecular sciences
  3. Journal of ethnopharmacology
  4. Molecules (Basel, Switzerland)
  5. International journal of biological macromolecules
View 1 additional sources
  1. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti

Adaptogenic

  1. Dr. Duke
  2. Journal of ethnopharmacology
  3. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti
  4. Journal of chromatography. A
  5. The EPMA journal

Neuroprotective

  1. Dr. Duke
  2. BMC genomics
  3. Nutrients
  4. International journal of biological macromolecules

Sedative

  1. Dr. Duke
  2. Environmental toxicology and pharmacology
  3. Journal of ethnopharmacology
  4. Naunyn-Schmiedeberg's archives of pharmacology

Anticancer

  1. Dr. Duke
  2. Chinese medicine
  3. Molecules (Basel, Switzerland)

Cardioprotective

  1. Dr. Duke
  2. BMC genomics
  3. International journal of biological macromolecules

Tonic

  1. Dr. Duke
  2. Environmental toxicology and pharmacology
  3. Journal of ethnopharmacology

Adaptogen

  1. International journal of molecular sciences
  2. Journal of ethnopharmacology

Antiangiogenic

  1. Dr. Duke
  2. Evidence-based complementary and alternative medicine : eCAM

Medicinal Uses

Schisandra chinensis has 83 reported medicinal uses identified across 43 scientific publications and several other databases. The most consistently reported uses include cancer, liver diseases, cardiovascular diseases, inflammation, oxidative stress.

Most Reported Uses

Use Sources Consensus
cancer Chinese medicine (and other 8 sources) ★★★★☆
liver diseases Naunyn-Schmiedeberg's archives of pharmacology (and other 6 sources) ★★★☆☆
cardiovascular diseases Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti (and other 4 sources) ★★☆☆☆
inflammation Nutrients (and other 4 sources) ★★☆☆☆
oxidative stress Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society (and other 4 sources) ★★☆☆☆
Alzheimer's disease Nutrients (and other 3 sources) ★★☆☆☆
antioxidant BMC genomics (and other 3 sources) ★★☆☆☆
fatigue Journal of ethnopharmacology (and other 3 sources) ★★☆☆☆
insulin resistance Nutrients (and other 3 sources) ★★☆☆☆
neuroinflammation Nutrients (and other 3 sources) ★★☆☆☆

Preparations

Preparations Sources Consensus
ethanol extract Molecules (Basel, Switzerland) (and other 3 sources) ★★☆☆☆
Schisandra chinensis extract Phytochemistry (and other 2 sources) ★☆☆☆☆
extracts International journal of molecular sciences (and other 2 sources) ★☆☆☆☆
5-hydroxymethyl-2-furfural (5-HMF) International journal of molecular sciences (and other 1 sources) ★☆☆☆☆
70% ethanol extracts Journal of separation science (and other 1 sources) ★☆☆☆☆
95% ethanol extract Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) ★☆☆☆☆
Alcoholic extract Yao xue xue bao = Acta pharmaceutica Sinica (and other 1 sources) ★☆☆☆☆
Dengzhan shengmai (DZSM) formula Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Extracts Nutrients (and other 1 sources) ★☆☆☆☆
Extracts from the leaves or fruits Journal of cellular and molecular medicine (and other 1 sources) ★☆☆☆☆