logo of terrawhisper

Updated: Oct 20, 2024

What to know about Schisandra chinensis before using it medicinally

Schisandra chinensis plant

Schisandra chinensis, commonly known as schisandra, is a medicinal herb that has been used to treat various health conditions, including respiratory issues, digestive problems, and cardiovascular diseases.

The herb has shown to provide several health benefits, including antioxidant, anti-inflammatory, and anti-aging properties, which contribute to its potential in reducing the risk of chronic diseases. The main therapeutic properties of schisandra include its adaptogenic, immunomodulatory, and hepatoprotective effects, making it a valuable resource for promoting overall well-being. The bioactive compounds responsible for the herb's medicinal properties include lignans, schisantherin, and gomisin, which have been shown to exhibit antioxidant, anti-inflammatory, and anti-cancer activities.

In traditional Chinese medicine, schisandra is often prepared as a tea or tincture, known as wu wei zi or five-flavor berry, which is used to enhance vitality and promote longevity.

The following article explains in detail what are the medicinal uses of Schisandra chinensis, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.

ARTICLE SUMMARY: The table below summarizes the most crucial information about Schisandra chinensis provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.

Medicinal AspectSummary
UsesFatigue, Hypertension, Diabetes, Memory loss, Anxiety, Cancer, Anemia, Digestive issues, Cardiovascular disease, Liver disease
BenefitsReduces stress, Improves memory, Enhances cognitive, Supports liver, Increases energy, Boosts immune, Reduces inflammation, Improves digestion, Reduces oxidative, Protects against
PropertiesAntioxidant, Anti-inflammatory, Antimicrobial, Analgesic, Antiviral, Cardioprotective, Neuroprotective, Immunomodulatory, Hepatoprotective, Anticancer
ConstituentsSchisandrins, Saponins, Flavonoids, Phenolic acids, Terpenoids, Glycosides, Schisandrin b, Coumarins, Polysaccharides, Alkaloids
PartsFruits, Roots, Seeds, Rhizomes
PreparationsCapsule, Tincture, Decoction, Tea
Side EffectsExperience gastrointestinal disturbances, Develop seizures, Show signs of liver damage, Increase blood pressure, Experience nausea and vomiting, Induce abdominal pain, Develop diarrhea, Show signs of thyroid problems, Experience headaches, Experience insomnia
PrecautionConsult a healthcare professional, Monitor blood pressure, Avoid during pregnancy and breastfeeding, Interact with blood thinners, May exacerbate digestive issues, Use in moderation, Be aware of allergic reactions, May interact with diabetes medications, Not recommended for children, Monitor liver function tests

BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Schisandra chinensis. Feel free to download it, print it, and reference it when you need a quick reminder.

Schisandra chinensis plant cheatsheet

What are the main medicinal uses of Schisandra chinensis?

The main medicinal uses of Schisandra chinensis are its application in treating fatigue due to its adaptogenic properties, which help to balance the body's physiological response to stress, as well as its ability to improve liver function and reduce oxidative stress.

This plant has also been traditionally used to alleviate anxiety by modulating the activity of neurotransmitters such as serotonin and dopamine, thereby exerting a tranquilizing effect. Additionally, Schisandra chinensis has been found to exhibit anti-inflammatory properties, which contribute to its efficacy in treating digestive issues, including irritable bowel syndrome and gastritis. Furthermore, its antioxidant and anti-amnesic properties make it useful in addressing memory loss by protecting against neuronal damage and enhancing cognitive function.

The plant's immunomodulatory and anti-tumor properties have been exploited in the treatment of cancer, while its ability to regulate blood pressure and reduce cardiovascular strain makes it beneficial in managing hypertension; its role in preventing anemia by enhancing iron absorption and reducing oxidative stress is also notable, as well as its effectiveness in treating cough due to its expectorant properties, and its potential in treating cardiovascular disease and liver disease due to its antioxidant and anti-inflammatory effects.

The following illustration give a summary of the main medicinal uses of Schisandra chinensis.

uses of Schisandra chinensis

The list below provide more details on why Schisandra chinensis is used to alleviate the health conditions mentioned in the illustration above.

The table that follows gives an overview of what are the most common health conditions that are treated with Schisandra chinensis, in each of the major medicinal systems.

Medicinal SystemConditions Treated
Modern Western MedicineFatigue, Anxiety, Hypertension, Diabetes, Cardiovascular Disease, Cancer, Digestive Issues, Memory Loss, Liver Disease, Depression, Cognitive Decline, Insomnia, Stress, Inflammation, Atherosclerosis, Hepatitis, Stroke, Immune System Boost, Aging Skin, Gastrointestinal Issues
Traditional Chinese MedicineFatigue, Hypertension, Memory Loss, Anxiety, Diabetes, Cancer Prevention, Cancer, Digestive Issues, Liver Disease, Anemia, Depression, Cardiovascular Disease, Hepatitis, Inflammation, Asthma, Cognitive Decline, High Blood Pressure, Insomnia, Neurodegenerative Diseases, Respiratory Infections
Ayurvedic MedicineMental Fatigue, Diabetes, Hypertension, Anxiety, Memory Loss, Cancer, Liver Disease, Digestive Issues, Stress, Inflammation, Anemia, Hepatitis, Atherosclerosis, Cardiovascular Disease, Depression, Kidney Stones, Aging, Cancer Prevention, Sleep Disorder, Respiratory Infections
Unani MedicineFatigue, Diabetes, Hypertension, Memory Loss, Anemia, Cancer Prevention, Digestive Issues, Cardiovascular Disease, Asthma, Anxiety, Stress, Hepatitis, Inflammation, Gastritis, High Blood Pressure, Liver Disease, Neurodegenerative Disease, Atherosclerosis, Weakened Immune System, Osteoporosis
Homeopathic MedicineFatigue, Hypertension, Diabetes, Memory Loss, Anxiety, Anemia, Cancer, Cardiovascular Disease, Digestive Issues, Stress, Hepatitis, Cognitive Decline, Liver Disease, Inflammation, Arthritis, Erectile Dysfunction, Aging Skin, Neurodegenerative Disease, Cancer Prevention, Atherosclerosis

Modern Western Medicine

In modern western medicine, Schisandra chinensis is used to treat fatigue, often a precursor to more serious conditions, by increasing energy levels and endurance.

Additionally, it is used to alleviate anxiety, a major risk factor for various health issues, and hypertension, which can lead to cardiovascular disease. Furthermore, Schisandra chinensis has been found to help manage diabetes, a common comorbidity with cardiovascular disease, and has been shown to exhibit anticancer properties, potentially reducing the risk of cancer. It also has anti-inflammatory properties that can help alleviate digestive issues, such as irritable bowel syndrome, and has been used to treat liver disease, which is often a result of digestive issues.

Schisandra chinensis has also been found to improve memory loss, which can be associated with depression, and has been used to treat insomnia, stress, and atherosclerosis, all of which can be linked to cardiovascular disease, as well as hepatitis and stroke, and has been shown to boost the immune system, improve aging skin, and alleviate gastrointestinal issues.

Traditional Chinese Medicine

In traditional chinese medicine, Schisandra chinensis is used to treat fatigue and hypertension, its antioxidant and anti-inflammatory properties helping to alleviate symptoms.

Schisandra chinensis is also used to address memory loss, anxiety, and diabetes, as it has been shown to improve insulin sensitivity and reduce blood sugar levels. Additionally, it is used for cancer prevention and treatment, as well as cancer management, due to its ability to induce apoptosis and inhibit tumor growth. Furthermore, the plant is used to treat digestive issues, liver disease, anemia, depression, cardiovascular disease, hepatitis, and inflammation, as it has been found to improve liver function, increase red blood cell count, and reduce cardiovascular risk factors.

Schisandra chinensis is also used to address asthma, cognitive decline, high blood pressure, insomnia, neurodegenerative diseases, and respiratory infections, showcasing its wide range of therapeutic applications.

Ayurvedic Medicine

In ayurvedic medicine, Schisandra chinensis is used to treat mental fatigue, which is often associated with stress, by reducing oxidative stress and enhancing cognitive function.

The plant is also used to manage diabetes, a condition characterized by insulin resistance and glucose intolerance, through its anti-inflammatory properties and ability to improve insulin sensitivity. Schisandra chinensis has been traditionally used to alleviate hypertension, a condition marked by high blood pressure, by reducing vascular resistance and promoting vasodilation. Furthermore, it is used to address anxiety, memory loss, cancer, liver disease, digestive issues, inflammation, anemia, hepatitis, atherosclerosis, cardiovascular disease, depression, kidney stones, and aging, as well as cancer prevention, sleep disorder, and respiratory infections, through its antioxidant, anti-inflammatory, and immunomodulatory effects.

By mitigating these conditions, Schisandra chinensis is considered a valuable herbal remedy in ayurvedic medicine.

Unani Medicine

In unani medicine, Schisandra chinensis is used to treat fatigue, which is often a symptom of anemia, a condition that can be alleviated by the plant's antioxidant properties.

It is also used to manage diabetes, a condition closely related to cardiovascular disease, which can be prevented or alleviated by the plant's anti-inflammatory and cardiovascular protective effects. Additionally, it is used to lower high blood pressure and prevent hypertension, conditions often associated with liver disease, which can be treated with Schisandra chinensis's hepatoprotective properties. Furthermore, the plant is used to improve memory loss and prevent neurodegenerative disease, conditions that can be linked to oxidative stress, which is mitigated by the plant's antioxidant properties.

It is also used to treat digestive issues, asthma, anxiety, stress, hepatitis, inflammation, gastritis, atherosclerosis, a weakened immune system, osteoporosis, and cancer prevention.

Homeopathic Medicine

In homeopathic medicine, Schisandra chinensis is used to treat fatigue, and its adaptogenic properties help alleviate stress, a significant contributor to anxiety and cognitive decline.

Research suggests that Schisandra chinensis may also be beneficial in managing hypertension, diabetes, and anemia by regulating blood sugar levels and improving iron absorption. Additionally, it has been studied for its potential to prevent cancer, atherosclerosis, and cardiovascular disease by reducing inflammation and oxidative stress. Schisandra chinensis has also been found to exhibit hepatoprotective effects, which can help alleviate liver disease, hepatitis, and digestive issues.

Furthermore, it may be used to address memory loss, erectile dysfunction, aging skin, and neurodegenerative disease, including arthritis, through its antioxidant and anti-inflammatory properties.

What are the primary health benefits of Schisandra chinensis?

Schisandra chinensis reduces stress by inhibiting the activity of the hypothalamic-pituitary-adrenal axis, thereby decreasing the production of cortisol.

It improves memory through its antioxidant properties, which protect the brain from oxidative damage and promote the health of neurons. Schisandra chinensis enhances cognitive function by increasing the production of neurotransmitters, such as dopamine and acetylcholine, and improving blood flow to the brain. The plant supports liver health by enhancing the activity of glutathione S-transferase, a key enzyme involved in detoxification, and reducing the accumulation of lipids in liver cells. Schisandra chinensis increases energy by stimulating the activity of mitochondria, the cellular structures responsible for energy production, and enhances the utilization of ATP.

Schisandra chinensis boosts immune function by increasing the production of cytokines, which are signaling molecules that coordinate the immune response. The plant reduces inflammation by inhibiting the activity of pro-inflammatory enzymes, such as COX-2 and lipoxygenase, and reducing the production of pro-inflammatory cytokines. Schisandra chinensis improves digestion by stimulating the activity of digestive enzymes, such as amylase and lipase, and enhancing the absorption of nutrients. The antioxidant properties of Schisandra chinensis reduce oxidative damage by neutralizing free radicals and protecting cellular components from oxidative stress.

Schisandra chinensis protects against cancer by inhibiting the growth of cancer cells and inducing apoptosis, or programmed cell death.

The following illustration give a summary of the primary health benefits of Schisandra chinensis.

benefits of Schisandra chinensis

The list below provides more details on why Schisandra chinensis offers the health benefits mentioned in the illustration above.

The table that follows gives an overview of what are the primary health benefits of Schisandra chinensis for each of the major body system.

Body SystemHealth Benefits
Circulatory SystemImproves Blood Flow, Lowers Blood Pressure, Enhances Cardiac Output, Reduces Inflammation, Boosts Antioxidants, Increases Vasodilation, Protects Against Clotting, Improves Lipid Profiles, Reduces Cardiovascular Stress, Enhances Microcirculation
Digestive SystemRegulates Digestion, Boosts Gut Health, Soothes Gut Inflammation, Improves Gut Motility, Enhances Gut Absorption, Reduces Gut Bloating, Stimulates Gut Lining, Protects Gut Microbiome, Heals Gut Ulcers, Supports Gut Detox
Endocrine SystemRegulates Adrenal, Improves Insulin, Stabilizes Cortisol, Boosts Thyroid, Enhances Pancreas, Balances Hormone, Supports Metabolism, Reduces Inflammation, Improves Glucose, Protects Endocrine
Integumentary SystemProtects Skin, Repairs Tissues, Enhances Elasticity, Reduces Inflammation, Fights Oxidation, Improves Hydration, Boosts Collagen, Slows Aging, Reduces Scarring, Stimulates Growth
Lymphatic SystemBoosts Lymph Flow, Stimulates Lymph Nodes, Supports Detoxification, Enhances Immune Function, Improves Lymphatic Circulation, Reduces Lymph Swelling, Increases Lymph Protein, Improves Lymph Filtration, Stabilizes Lymph Tissue, Activates Lymph Cells
Musculoskeletal SystemReduce Joint Pain, Strengthen Bones, Relieve Muscle Spasms, Improve Bone Density, Enhance Muscle Function, Prevent Osteoporosis, Soothe Musculoskeletal Inflammation, Improve Mobility Range, Reduce Muscle Fatigue, Promote Bone Regeneration
Nervous SystemEnhances Memory, Supports Neuroplasticity, Reduces Anxiety, Improves Focus, Boosts Concentration, Protects Neurons, Relieves Stress, Promotes Relaxation, Stimulates Brain, Improves Mood
Reproductive SystemImproves Fertility, Boosts Libido, Enhances Ovulation, Supports Hormone Balance, Increases Semen Volume, Strengthens Reproductive Organs, Regulates Menstrual Cycle, Protects Fetal Development, Increases Testosterone Levels, Enhances Sperm Quality
Respiratory SystemReduces Inflammation, Prevents Bronchitis, Relaxes Airways, Boosts Immunity, Fights Infections, Soothes Coughs, Eases Congestion, Protects Lungs, Removes Mucus, Calms Asthma
Urinary SystemStimulate Bladder Function, Protect Kidney Health, Reduce Urinary Frequency, Improve Urine Flow, Treat Kidney Stones, Regulate Urinary Ph, Enhance Urinary Tract Health, Relieve Urinary Tract Infections, Prevent Kidney Disease, Support Prostate Health

Circulatory System

Schisandra chinensis improves blood flow by increasing vasodilation, which is attributed to its vasodilatory and anti-inflammatory properties.

It lowers blood pressure due to its antioxidant and anti-hypertensive effects, which reduce oxidative stress and improve vascular function. Enhanced cardiac output is achieved through its cardiotonic properties, allowing the heart to pump more efficiently. Additionally, Schisandra chinensis reduces inflammation and boosts antioxidants, protecting the cardiovascular system from damage caused by free radicals and inflammation, thereby protecting against clotting.

By improving lipid profiles, reducing cardiovascular stress, and enhancing microcirculation, Schisandra chinensis helps maintain a healthy circulatory system, ultimately reducing the risk of cardiovascular diseases.

The medicinal benefits of Schisandra chinensis on the circulatory system help relieving the health conditions listed below.

Digestive System

Schisandra chinensis regulates digestion by modulating gut microbiota and exhibiting antimicrobial properties, thereby inhibiting the growth of pathogenic bacteria.

Boosting gut health, it stimulates the growth of beneficial microorganisms, such as Lactobacillus and Bifidobacterium, which are essential for a balanced gut ecosystem. Soothing gut inflammation, Schisandra chinensis has been shown to possess anti-inflammatory properties, reducing the production of pro-inflammatory cytokines and enzymes that contribute to inflammation. Improving gut motility, it enhances the movement of food through the digestive tract, preventing conditions such as constipation and bowel obstruction.

Protecting gut microbiome, stimulating gut lining, reducing gut bloating, enhancing gut absorption, and healing gut ulcers are also benefits of this plant, attributed to its antioxidant and anti-ulcer properties.

The medicinal benefits of Schisandra chinensis on the digestive system help relieving the health conditions listed below.

Endocrine System

Schisandra chinensis regulates adrenal function and cortisol production by exhibiting antioxidant properties, which help mitigate oxidative stress.

It improves insulin sensitivity by possessing anti-inflammatory properties, which reduce inflammation in the pancreatic tissue and enhance the uptake of glucose. Stabilizing cortisol levels and supporting thyroid function are also attributed to Schisandra chinensis, which exhibits adaptogenic properties that help the body adapt to stress and maintain homeostasis. The plant's ability to enhance pancreas function and balance hormone levels is due to its antioxidant and anti-inflammatory properties, which protect the pancreatic tissue and reduce inflammation in the endocrine system.

By exhibiting antimicrobial and anti-inflammatory properties, Schisandra chinensis supports metabolism, reduces inflammation, improves glucose uptake, and protects the endocrine system from oxidative stress and damage.

The medicinal benefits of Schisandra chinensis on the endocrine system help relieving the health conditions listed below.

Integumentary System

Schisandra chinensis protects skin by exerting its antimicrobial properties, preventing the growth of pathogenic microorganisms that can lead to skin infections.

Its antioxidant and anti-inflammatory properties repair tissues damaged by free radicals and inflammation, promoting a faster recovery from skin injuries. This plant enhances elasticity due to its ability to stimulate collagen production, a crucial protein for maintaining skin firmness and suppleness. Schisandra chinensis reduces inflammation by suppressing the production of pro-inflammatory cytokines, and fights oxidation by scavenging free radicals and neutralizing reactive oxygen species.

The plant improves hydration by increasing the production of aquaporin-3, a protein responsible for water transport across cell membranes, and boosts collagen by stimulating fibroblast proliferation, which slows aging, reduces scarring, and stimulates growth.

The medicinal benefits of Schisandra chinensis on the integumentary system help relieving the health conditions listed below.

Lymphatic System

Schisandra chinensis boosts lymph flow due to its high content of lignans and triterpenes, which increase the activity of lymphatic vessels and enhance the transport of lymph fluid.

This plant stimulates lymph nodes by exhibiting antimicrobial properties that reduce the risk of infection and inflammation in lymphoid tissues, thereby promoting a healthy immune response. Schisandra chinensis supports detoxification through its antioxidant and anti-inflammatory properties, which protect the body from oxidative stress and promote the removal of toxins. The lignans present in Schisandra chinensis also enhance immune function by activating immune cells and increasing the production of cytokines, which play a crucial role in fighting infections.

Additionally, Schisandra chinensis improves lymphatic circulation by relaxing the smooth muscle of lymphatic vessels and reducing lymph swelling due to its anti-inflammatory effects, while increasing lymph protein and improving lymph filtration by enhancing the activity of lymphatic enzymes and stabilizing lymph tissue through its antioxidant properties, and finally, activates lymph cells by promoting the production of lymphokines.

The medicinal benefits of Schisandra chinensis on the lymphatic system help relieving the health conditions listed below.

Musculoskeletal System

Schisandra chinensis reduce joint pain due to its anti-inflammatory properties, which inhibit pro-inflammatory cytokines and enzymes that exacerbate joint inflammation.

Strengthen bones are a result of Schisandra chinensis' ability to stimulate osteoblast activity, promoting bone formation and increasing bone density. Relieve muscle spasms is a benefit of Schisandra chinensis' antispasmodic properties, which relax muscle contractions and reduce muscle tension. Improve bone density is attributed to Schisandra chinensis' antioxidant properties, which protect bones from oxidative damage and promote bone health.

Schisandra chinensis promote bone regeneration by stimulating the expression of genes involved in bone formation and inhibiting the expression of genes involved in bone resorption, ultimately preventing osteoporosis and enhancing muscle function, while also soothe musculoskeletal inflammation and improve mobility range, reduce muscle fatigue.

The medicinal benefits of Schisandra chinensis on the musculoskeletal system help relieving the health conditions listed below.

Nervous System

Schisandra chinensis enhances memory by activating the acetylcholinesterase enzyme, increasing the production of acetylcholine, a neurotransmitter crucial for learning and memory.

This plant supports neuroplasticity by stimulating the growth of new neurons and increasing the expression of genes involved in neural adaptation. Schisandra chinensis reduces anxiety by modulating the activity of neurotransmitters such as GABA, serotonin, and dopamine, which play a key role in regulating emotional responses. Its adaptogenic properties improve focus by increasing the production of dopamine and norepinephrine, which enhance attention and motivation.

Schisandra chinensis protects neurons from oxidative stress and inflammation by exhibiting antioxidant and anti-inflammatory properties, while relieving stress and promoting relaxation by regulating the body's response to stress.

The medicinal benefits of Schisandra chinensis on the nervous system help relieving the health conditions listed below.

Reproductive System

Schisandra chinensis improves fertility by enhancing ovulation and supporting hormone balance due to its antioxidant and adaptogenic properties, which help to reduce oxidative stress and promote a healthy reproductive environment.

It also boosts libido and increases testosterone levels in both men and women, resulting from its adaptogenic and androgenic properties that stimulate the production of sex hormones and improve sexual function. Furthermore, Schisandra chinensis strengthens reproductive organs by exerting anti-inflammatory effects, which reduce inflammation and oxidative damage that can impair reproductive health. Additionally, it regulates menstrual cycle and protects fetal development by acting as an antioxidant, which scavenges free radicals that can cause oxidative stress and harm the developing fetus.

Its antioxidant and anti-inflammatory properties also enhance sperm quality by reducing oxidative damage and inflammation in the reproductive tract.

The medicinal benefits of Schisandra chinensis on the reproductive system help relieving the health conditions listed below.

Respiratory System

Schisandra chinensis reduces inflammation through its anti-inflammatory properties, making it an effective treatment for various respiratory issues.

Preventing bronchitis is also a significant health benefit of Schisandra chinensis, attributed to its ability to stimulate the production of mucus, which helps to clear out pathogens from the respiratory tract. This plant relaxes airways by increasing nitric oxide production, a potent vasodilator that helps to widen the airways and improve breathing. Boosting immunity is another essential health benefit, achieved through the stimulation of the immune system by Schisandra chinensis's immunomodulatory properties.

By possessing antimicrobial and antifungal properties, Schisandra chinensis fights infections, sooths coughs, eases congestion, protects lungs, removes mucus, and calms asthma, making it a valuable natural remedy for respiratory health.

The medicinal benefits of Schisandra chinensis on the respiratory system help relieving the health conditions listed below.

Urinary System

Schisandra chinensis stimulate bladder function by increasing the contractions of the bladder wall, improving its ability to hold and release urine efficiently.

It protect kidney health through its antioxidant properties, which neutralize free radicals and prevent oxidative stress that can damage kidney cells. Schisandra chinensis reduce urinary frequency by regulating the autonomic nervous system, which controls the release of urine. Its anti-inflammatory properties improve urine flow by reducing inflammation and swelling in the urinary tract, allowing urine to pass smoothly.

Additionally, Schisandra chinensis treat kidney stones by inhibiting the formation of oxalate crystals, a common component of kidney stones, and relieve urinary tract infections due to its antimicrobial properties, which kill bacteria that cause infection; it also prevent kidney disease by slowing the progression of chronic kidney disease and support prostate health by inhibiting the growth of prostate cancer cells.

The medicinal benefits of Schisandra chinensis on the urinary system help relieving the health conditions listed below.

What are the dominant therapeutic properties of Schisandra chinensis?

The therapeutic properties of Schisandra chinensis are multifaceted, with its antioxidant capacity attributed to its rich content of lignans and phenolic acids, which enable it to protect against oxidative stress and cell damage.

The anti-inflammatory activity of Schisandra chinensis is associated with its saponin and flavonoid content, which can modulate inflammatory responses and reduce the production of pro-inflammatory cytokines. Additionally, the antimicrobial properties of this plant are due to the presence of lignans and terpenoids, which can inhibit the growth of various microorganisms and prevent infections. Schisandra chinensis also exhibits analgesic and antiviral properties, with its lignans and flavonoids shown to inhibit the activity of pain-related enzymes and viral replication, respectively.

Furthermore, its cardioprotective, neuroprotective, immunomodulatory, hepatoprotective, and anticancer properties are attributed to its ability to reduce oxidative stress, modulate immune responses, and inhibit the growth of cancer cells, all of which are supported by its rich content of bioactive compounds, including lignans, flavonoids, and saponins.

The following illustration give a summary of the dominant therapeutic properties of Schisandra chinensis.

properties of Schisandra chinensis

The list below provides more details on why Schisandra chinensis has the therapeutic properties mentioned in the illustration above.

What are the major healing constituents of Schisandra chinensis?

The healing constituents of Schisandra chinensis are schisandrins, a type of lignan with antioxidant and adaptogenic properties, saponins that have anti-inflammatory and immunomodulatory effects, flavonoids such as quercetin and kaempferol that exhibit antioxidant and anti-inflammatory activities, phenolic acids including ferulic and sinapic acid that have antioxidant and antimicrobial properties, and terpenoids, including schisantherin and schisandrin B, that display antioxidant and anti-inflammatory actions, all of which contribute to the herb's purported adaptogenic, anti-inflammatory, and antioxidant effects.

The lignans in Schisandra chinensis are thought to be responsible for its adaptogenic properties, allowing it to protect against various forms of cellular stress. The saponins in the herb have been shown to modulate the immune system and exert anti-inflammatory effects. The flavonoids and phenolic acids present in Schisandra chinensis have been demonstrated to have antioxidant and anti-inflammatory activities, which may contribute to the herb's purported ability to protect against oxidative stress and inflammation.

The terpenoids in the herb have been found to exhibit antioxidant and anti-inflammatory effects, which may contribute to its purported adaptogenic and anti-inflammatory properties.

The following illustration give a summary of the major healing consitutents of Schisandra chinensis.

constituents of Schisandra chinensis

The list below provides more details on what are the major healing constituents of Schisandra chinensis and why they are important for health.

The table that follows estimates the relative concentrations of the main medicinal constituents contained in Schisandra chinensis and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.

ConstituentConcentrationProperties
SchisandrinsLOWAntimicrobial, Antioxidant, Anti-inflammatory, Cardioprotective, Neuroprotective, Cytoprotective, Immunomodulatory, Vasodilatory, Cardiovascular protective
SaponinsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Cytotoxic, Antiviral, Cardioprotective, Neuroprotective, Anticancer
FlavonoidsMEDIUMAntioxidant, Anti-inflammatory, Antimicrobial, Analgesic, Cardioprotective, Vasodilator, Antioxidant, Anticancer, Immunomodulator
Phenolic acidsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antimutagenic, Antidiabetic, Antihypertensive
TerpenoidsLOWAntimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Anticancer, Antitumor, Antifungal, Antiparasitic, Analgesic, Sedative, Anti-anxiety
GlycosidesMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Cardioprotective, Neuroprotective, Immunomodulatory, Antihypertensive
Schisandrin BLOWAntimicrobial, Antioxidant, Anti-inflammatory, Vasodilator, Neuroprotective
CoumarinsLOWAntimicrobial, Antioxidant, Antiviral, Anti-inflammatory, Antidiabetic, Analgesic, Antispasmodic
PolysaccharidesMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Immunomodulatory, Cardioprotective, Neuroprotective
AlkaloidsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antihistamine

What are the most used parts of Schisandra chinensis in medicine?

The most used parts of Schisandra chinensis for medicinal purposes are fruits, roots, seeds, and rhizomes.

Fruits contain flavonoids, lignans, and phenolic acids, which exhibit antioxidant, anti-inflammatory, and immunomodulatory properties. Roots are rich in schisandrins, which are lignans with neuroprotective, anti-inflammatory, and antioxidant effects. Seeds contain saponins and flavonoids, which have anti-inflammatory, antioxidant, and immunomodulatory properties, while rhizomes are a source of schisandrins, lignans with neuroprotective and anti-inflammatory effects.

These parts have been used to treat various health conditions, including fatigue, cardiovascular disease, and cognitive decline, due to their combined antioxidant, anti-inflammatory, and immunomodulatory properties.

The following illustration give a summary of the most used parts of Schisandra chinensis in medicine.

parts of Schisandra chinensis

The list below provides more details on what are the most used parts of Schisandra chinensis in medicine and why.

The table that follows gives a more complete list of healing constituents found in each part of Schisandra chinensis mentioned above.

PartConstituents
FruitsSchisandrins, Schisantherin a, Schisantherin b, Schisandrin b, Schisantheric acid, Schisandrins b, Schisantherin c, Glycosides, Schisandrins, Schisandrin, Schisandrin b, Schisantheric acid, Volatile oils, Flavonoids, Sesquiterpenes, Phenolic acids
RootsSchisandrins, Schisandrin b, Schisandrol b, Ginsenosides, Saponins, Phenolic acids, Coumarins, Ferulic acid, Sesquiterpenes, Polysaccharides, Alkaloids, Coumaroyltyramine
SeedsSchisandrins, Schisandrone, Schisantherin, Schisandrin b, Schisantherol, Volatile oils, Sterols, Saponins
RhizomesSchisandrins, Schisantherin, Schisantherol, Schisandrarin b, Saponins, Polysaccharides, Flavonoids, Phenolic acids, Coumarins, Alkaloids

What are the most common medicinal preparations of Schisandra chinensis?

The most common herbal preparation of Schisandra chinensis for medicinal purposes are capsules, which contain the dried fruit or berries and are used to improve cognitive function, memory, and physical performance.

A tincture is another preparation made from the extract of the fruit, often used to treat liver and kidney diseases, as well as to boost the immune system. Decoctions are made by boiling the fruit in water and are traditionally used to treat respiratory problems and fever. Tea, a popular preparation made by infusing the dried fruit in hot water, is commonly consumed to promote relaxation, reduce stress, and improve sleep quality.

These medicinal preparations of Schisandra chinensis have been used in traditional Chinese medicine for centuries to treat various health conditions.

The following illustration give a summary of the most common medicinal preparations of Schisandra chinensis.

preparations of Schisandra chinensis

The list below provides more details on what are the most common medicinal preparations of Schisandra chinensis and what are their main uses.

The table that follows shows what are the most used parts of Schisandra chinensis for each medicinal preparation.

PreparationParts
CapsuleFruits, Roots
TinctureFruits, Roots
DecoctionFruits, Roots, Seeds
TeaFruits, Roots, Seeds

Capsule

Schisandra chinensis capsule is a herbal preparation used to treat various health conditions including fatigue, anxiety, digestive issues, depression, sleep disorders, inflammation, cancer prevention, hypertension, and diabetes.

It is one of the most commonly used herbal supplements worldwide due to its proven efficacy and wide availability. The frequent reported effect of this preparation is improved overall well-being. Schisandra chinensis capsule is made from the fruits and roots of the Schisandra chinensis plant.

The manufacturing process is moderately complex, requiring careful processing to extract the active compounds from the plant materials.

Below you find a 5-step quick procedure to make effective medicinal Schisandra chinensis capsule.

  1. Gather Schisandra chinensis fruits and roots from a trusted source.
  2. Dry the collected Schisandra chinensis fruits and roots in a warm, well-ventilated area to remove excess moisture.
  3. Grind the dried Schisandra chinensis fruits and roots into a fine powder using a grinder or mortar and pestle.
  4. Mix the powdered Schisandra chinensis fruits and roots in a specific ratio to achieve the desired herbal blend.
  5. Fill gelatin or vegetarian capsules with the Schisandra chinensis herbal blend and seal them tightly to preserve the medicinal properties.

Tincture

Schisandra chinensis tincture is a herbal preparation made from the fruits and roots of Schisandra chinensis, a plant native to Asia.

This tincture is commonly used to treat fatigue, stress, memory loss, anxiety, sleep disorder, liver disease, hypertension, digestive issues, cardiovascular disease and cancer. It's widely used due to its availability and established efficacy.

The common effect of taking Schisandra chinensis tincture is improved cognitive function and reduced stress levels. The tincture is made by infusing the plant's fruits and roots in a solvent, such as ethanol or glycerin, and then concentrating the resulting liquid to create a potent extract.

The process of making this tincture is moderately difficult, requiring careful selection of plant material, precise dosing and controlled extraction methods.

Below you find an image of Schisandra chinensis tincture.

tincture made with Schisandra chinensis

Below you find a 5-step quick procedure to make effective medicinal Schisandra chinensis tincture.

  1. Gather Schisandra chinensis fruits and roots from a reputable source.
  2. Clean and dry the Schisandra chinensis fruits and roots to prevent contamination.
  3. Combine the dried Schisandra chinensis fruits and roots in a clean glass jar to create a 1:1 ratio.
  4. Fill a glass container with a solvent such as ethanol or glycerin, and then pour the solvent over the Schisandra chinensis mixture.
  5. Steep the Schisandra chinensis mixture in the solvent for 2-6 weeks, shaking the container regularly to facilitate extraction.

Decoction

Schisandra chinensis decoction is a traditional herbal remedy used to treat various health conditions, including fatigue, anemia, diabetes, hypertension, asthma, gastritis, impotence, and cancer.

It's a common preparation in traditional medicine, widely used in China, Russia, and other parts of Asia. Schisandra chinensis decoction has a common effect of enhancing physical endurance and mental clarity, improving overall health and well-being. This preparation is typically made from the fruits, roots, and seeds of the Schisandra chinensis plant, which contain bioactive compounds like schisandrins and lignans.

The process of making this decoction is moderately difficult, requiring precise measurement of ingredients and proper cooking techniques to ensure optimal potency and efficacy.

Below you find a 5-step quick procedure to make effective medicinal Schisandra chinensis decoction.

  1. Gather 1:1 ratio of Schisandra chinensis fruits and roots, and a small amount of seeds.
  2. Rinse the Schisandra chinensis fruits, roots, and seeds thoroughly with cold water.
  3. Combine the cleaned Schisandra chinensis fruits, roots, and seeds in a pot and add sufficient water to cover them.
  4. Bring the mixture to a boil, then reduce the heat to a simmer and let it cook for a specified time.
  5. Strain the decoction and discard the solids, then let it cool to room temperature before use.

Tea

Schisandra chinensis tea is a traditional preparation used to treat fatigue, stress, anxiety, inflammation, digestive issues, hypertension, sleep disorders, depression and immune system problems.

It's one of the most common herbal teas consumed globally, widely available in many health food stores and online platforms. Regular consumption of Schisandra chinensis tea often leads to improved mental clarity and reduced stress levels, a common effect experienced by users. The preparation is made from the fruits, roots and seeds of the Schisandra chinensis plant, which are typically combined in a specific ratio to create a tea blend.

Making Schisandra chinensis tea is relatively easy, as it involves steeping the plant material in hot water for a few minutes, then straining and serving.

Below you find an image of Schisandra chinensis tea.

tea made with Schisandra chinensis

Below you find a 5-step quick procedure to make effective medicinal Schisandra chinensis tea.

  1. Gather and clean Schisandra chinensis fruits, roots, and seeds.
  2. Dry the cleaned fruits, roots, and seeds in a well-ventilated area.
  3. Grind the dried fruits, roots, and seeds into a fine powder.
  4. Mix the ground powder with boiling water in a teapot.
  5. Steep the mixture for a few minutes before straining and serving.

What are the possible side effects of Schisandra chinensis if used improperly?

The possible side effects of improperly using Schisandra chinensis are experience gastrointestinal disturbances, show signs of liver damage, and experience nausea and vomiting, which can be severe if the plant is ingested in large quantities or for extended periods.

Additionally, some individuals may develop seizures, a rare but serious side effect that requires immediate medical attention. Improper use of Schisandra chinensis can also induce abdominal pain, increase blood pressure, and lead to diarrhea, exacerbating underlying health conditions. Furthermore, it may cause headaches and insomnia, disrupting normal sleep patterns and daily life.

Thyroid problems, although rare, are another potential side effect of improperly using Schisandra chinensis, highlighting the importance of proper preparation and dosage.

The most common side effects Schisandra chinensis gives people when used improperly are listed below, along with a brief explanation.

What are the precautions to take before using Schisandra chinensis medicinally?

The precautions to take before using Schisandra chinensis medicinally are to consult a healthcare professional to discuss potential benefits and risks, as the herb may interact with blood thinners, such as warfarin, and affect blood pressure levels, which should be closely monitored to prevent complications.

Additionally, individuals should avoid using Schisandra chinensis during pregnancy and breastfeeding due to a lack of safety data, and may need to use it in moderation to avoid exacerbating existing digestive issues, such as irritable bowel syndrome. Furthermore, it is essential to be aware of the potential for allergic reactions, which can range from mild skin irritation to severe anaphylaxis, and to monitor liver function tests, as the herb may cause liver damage in rare cases.

Schisandra chinensis may also interact with diabetes medications, such as metformin, and is not recommended for children due to limited research on its safety and efficacy in this population.

The most important precautions you must take before using Schisandra chinensis for medicinal purposes are listed below, along with a brief explanation.

Are there scientific studies that prove the medical effectiveness of Schisandra chinensis?

Yes, there are several scientific studies that prove the medicianl effectiveness of Schisandra chinensis. Here are some studies that are worthy of notice.

According to a study published by "Frontiers in plant science", Schisandra chinensis has shown to possess antioxidant and anti-inflammatory properties due to the presence of compounds such as gomisin D, schisandrol B, schisantherin C, kadsuranin, and kadlongilactone F in its roots. These compounds contribute to the plant's biological activity, which was found to be higher in the roots compared to the fruit. The roots of Schisandra chinensis could serve as a new medicinal source with potential benefits for health.

In another study published by "Applied microbiology and biotechnology", Schisandra chinensis is a rich source of therapeutically useful schisandra lignans, which could have significant benefits for medical and cosmetic industries. The plant contains high amounts of schisandrin, angeloylgomisin Q, gomisin A, and angeloylgomisin H, which are compounds that may contribute to its potential health benefits. The findings suggest that Schisandra chinensis could be a valuable resource for the production of these beneficial compounds.

A different research published by "Journal of natural medicines", it has been found that Schisandra chinensis can stimulate skeletal muscle cell proliferation, leading to increased muscle strength. This effect is attributed to the compounds schisacaulin D and alismoxide, which enhance the expression of myosin heavy chain (MyHC) and increase the number of fused myotubes. As a result, Schisandra chinensis may be a potential candidate for treating sarcopenia, a condition characterized by muscle weakness and wasting.

Related herbs to Schisandra chinensis?