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Updated: Jul 21, 2024

10 Possible Side Effects Of Rehmannia Glutinosa (Chinese Foxglove)

rehmannia glutinosa

Rehmannia glutinosa, also known as Chinese foxglove, has some side effects when used improperly, such as gastrointestinal disturbances, allergic reactions, and cardiovascular issues.

These side effects can arise from excessive doses, interactions with other medications, or individual sensitivities. For instance, gastrointestinal problems can lead to dehydration, nutrient deficiencies, and fatigue, impairing one's daily activities and productivity.

Allergic reactions can cause anaphylaxis, which can be life-threatening if not treated promptly.

This article explains in details the 10 most common side effects of Rehmannia glutinosa if used imporperly.

1. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese Foxglove, causes kidney stones to form due to its high concentration of oxalates and other minerals.

The excessive absorption of these substances in the body can lead to an increase in urinary oxalate levels, which can combine with calcium ions to form kidney stones.

Additionally, Rehmannia glutinosa's saponins may also contribute to increased urine output, potentially diluting the concentration of other minerals and further exacerbating the issue.

2. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese Foxglove, triggers blood sugar spike due to its ability to increase insulin secretion and improve glucose uptake in the body.

This property makes it an effective treatment for diabetes, but may cause an unintended elevation in blood sugar levels for individuals already experiencing hyperglycemia or those with impaired glucose tolerance.

As a result, regular monitoring of blood sugar levels is crucial when using this herb as a natural remedy.

3. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese Foxglove, increases bleeding risk due to its ability to thin the blood and interfere with platelet function.

The herb contains compounds that inhibit platelet aggregation, making it more difficult for blood to clot normally, which can lead to excessive bleeding or bruising.

This increased bleeding risk is particularly concerning for individuals already taking anticoagulant medications or undergoing surgical procedures.

4. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese foxglove, induces severe allergic reactions.

This is likely due to the high concentration of bioactive compounds such as saponins, flavonoids, and alkaloids present in the plant, which can trigger an immune response in some individuals.

Additionally, the plant's ability to interact with the body's hormone regulation systems may also contribute to its allergenic potential.

5. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese Foxglove, worsens high blood pressure by increasing the production of aldosterone, a hormone that regulates electrolyte and water balance in the body.

As a result, it can increase blood pressure in individuals who already have hypertension or are prone to it due to their genetic makeup or other underlying health conditions.

Additionally, Rehmannia glutinosa's diuretic properties may also contribute to increased blood pressure by causing excessive urination, leading to dehydration and further elevating blood pressure.

6. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese foxglove, interacts with warfarin toxic.

This interaction is attributed to its ability to increase the metabolism of warfarin, leading to decreased plasma concentrations and potentially reduced therapeutic effects. Additionally, Rehmannia glutinosa may inhibit platelet aggregation, further exacerbating bleeding complications in patients taking warfarin.

The herb's saponins and alkaloids are thought to contribute to this adverse reaction.

7. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese Foxglove, enhances heavy metal toxicity due to its ability to increase the absorption of certain metals in the body.

Its saponins and flavonoids can stimulate the gut to release stored toxins, including heavy metals such as lead, mercury, and arsenic, which can then be re-absorbed into the bloodstream at higher levels than before treatment.

This increased bioavailability of heavy metals can lead to adverse effects on various bodily systems.

8. Worsens liver function impairment

9. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese foxglove, stimulates excessive urination due to its ability to increase blood flow and promote diuresis.

The plant's compounds, such as rehmannioside, have a direct impact on the kidneys, causing an increased frequency of urination.

This side effect is particularly pronounced in individuals who are already experiencing kidney issues or those with pre-existing conditions that affect urinary function.

10. Worsens liver function impairment

Rehmannia glutinosa, also known as Chinese Foxglove, aggravates adrenal insufficiency by suppressing the production of adrenocorticotropic hormone (ACTH), which plays a crucial role in regulating cortisol levels.

As Rehmannia glutinosa inhibits ACTH production, it can disrupt the normal functioning of the adrenal glands, leading to a decrease in cortisol output and exacerbating adrenal insufficiency.

This interaction may result in symptoms such as fatigue, weakness, and low blood pressure.