By Leen Randell
Updated: Oct 21, 2024
What to know about Rehmannia glutinosa before using it medicinally
Rehmannia glutinosa, commonly known as rehmannia, is a traditional Chinese medicinal herb used to treat various health conditions, including anemia, fatigue, and kidney diseases.
The main health benefits of rehmannia include its ability to promote blood circulation, reduce inflammation, and improve immune function. The herb's main therapeutic properties are attributed to its anti-inflammatory, antioxidant, and immunomodulatory activities. The bioactive compounds responsible for these effects include rehmannioside A, rehmannioside B, and rehmannin, which have been shown to possess anti-inflammatory and antioxidant properties.
In traditional Chinese medicine, rehmannia is often prepared as a decoction or powder and used to make herbal formulations such as Huang Qi Jian Zhong Tang, a classic formula used to treat anemia and fatigue.
The following article explains in detail what are the medicinal uses of Rehmannia glutinosa, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.
ARTICLE SUMMARY: The table below summarizes the most crucial information about Rehmannia glutinosa provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.
| Medicinal Aspect | Summary |
|---|---|
| Uses | Anemia, Hypertension, Diabetes, Kidney stones, Hemorrhoids, Menstrual disorder, Asthma, Diarrhea, Arthritis, Menopause |
| Benefits | Antioxidant protects, Inhibits cancer cells, Reduces inflammation, Prevents kidney damage, Lowers blood pressure, Improves cognitive function, Boosts immune system, Treats menopausal symptoms, Soothes digestive issues, Reduces oxidative stress |
| Properties | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Pain relief, Hypotensive, Immunomodulatory, Neuroprotective, Anticonvulsant |
| Constituents | Saponins, Flavonoids, Alkaloids, Phenolic acids, Triterpenoids, Iridoid glycosides, Coumarins, Iridoid glycosides, Polysaccharides, Anthraquinones |
| Parts | Roots, Rhizomes |
| Preparations | Tincture, Capsule, Decoction, Tea |
| Side Effects | Abnormal heart rhythms, Abnormal uterine bleeding, Anemia, Bruising, Decreased platelet count, Diarrhea, Hemolytic anemia, Nausea, Renal impairment, Thrombocytopenia |
| Precaution | Consult a healthcare professional, Use in moderation, Monitor blood sugar levels, Avoid during pregnancy, Be cautious with diabetes, Monitor kidney function, Avoid with low blood pressure, Be cautious with bleeding disorders, Avoid with liver disease, Monitor for allergic reactions |
BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Rehmannia glutinosa. Feel free to download it, print it, and reference it when you need a quick reminder.
- What are the main medicinal uses of Rehmannia glutinosa?
- Modern Western Medicine
- Traditional Chinese Medicine
- Ayurvedic Medicine
- Unani Medicine
- Homeopathic Medicine
- What are the primary health benefits of Rehmannia glutinosa?
- Circulatory System
- Digestive System
- Endocrine System
- Integumentary System
- Lymphatic System
- Musculoskeletal System
- Nervous System
- Reproductive System
- Respiratory System
- Urinary System
- What are the dominant therapeutic properties of Rehmannia glutinosa?
- What are the major healing constituents of Rehmannia glutinosa?
- What are the most used parts of Rehmannia glutinosa in medicine?
- What are the most common medicinal preparations of Rehmannia glutinosa?
- What are the possible side effects of Rehmannia glutinosa if used improperly?
- What are the precautions to take before using Rehmannia glutinosa medicinally?
- Related herbs to Rehmannia glutinosa?
What are the main medicinal uses of Rehmannia glutinosa?
The main medicinal uses of Rehmannia glutinosa are the treatment of anemia, which is attributed to its high content of iron and other essential minerals, as well as menorrhagia, due to its ability to reduce menstrual blood loss through the action of its glycosides and flavonoids.
This plant is also used to alleviate diarrhea, a symptom that can be relieved by the prebiotic properties of its polysaccharides, which promote the growth of beneficial gut bacteria. Additionally, Rehmannia glutinosa is employed to mitigate menopausal symptoms, such as hot flashes and mood swings, through its estrogen-like activity, which is mediated by its isoflavones and saponins. Furthermore, it has been used to treat hemorrhoids, fatigue, kidney stones, menopausal symptoms, dysmenorrhea, and diabetes, with its constituents, including alkaloids and phenolic acids, contributing to its antidiarrheal, anti-inflammatory, and antioxidant properties.
The combination of these bioactive compounds in Rehmannia glutinosa provides a unique therapeutic profile that has made it a valuable herbal remedy in traditional medicine.
The following illustration give a summary of the main medicinal uses of Rehmannia glutinosa.
The list below provide more details on why Rehmannia glutinosa is used to alleviate the health conditions mentioned in the illustration above.
- Anemia: This plant is used for anemia due to its high content of iron and other essential minerals, which can help increase red blood cell count and alleviate symptoms associated with iron deficiency.
- Hypertension: This plant is used for hypertension as it is believed to have a hypotensive effect, which can help lower blood pressure by inhibiting the activity of the sympathetic nervous system and reducing vascular resistance.
- Diabetes: This plant is used for diabetes as it has been shown to have a hypoglycemic effect, which can help lower blood sugar levels by increasing insulin sensitivity and inhibiting the activity of enzymes involved in glucose production.
- Kidney Stones: This plant is used for kidney stones as it is believed to have a litholytic effect, which can help dissolve and eliminate kidney stones by increasing the excretion of calcium and oxalate in the urine.
- Hemorrhoids: This plant is used for hemorrhoids as it has been shown to have a venotonic effect, which can help improve blood circulation and reduce inflammation in the rectal veins, alleviating symptoms associated with hemorrhoids.
- Menstrual Disorder: This plant is used for menstrual disorders as it is believed to have an estrogen-like effect, which can help regulate menstrual cycles and alleviate symptoms associated with menstrual cramps, PMS, and menopausal hot flashes.
- Asthma: This plant is used for asthma as it has been shown to have a bronchodilatory effect, which can help relax bronchial muscles and improve lung function, alleviating symptoms associated with asthma.
- Diarrhea: This plant is used for diarrhea as it is believed to have an anti-inflammatory and protective effect on the intestinal mucosa, which can help reduce inflammation and alleviate symptoms associated with diarrhea.
- Arthritis: This plant is used for arthritis as it has been shown to have an anti-inflammatory and analgesic effect, which can help reduce inflammation and alleviate pain associated with arthritis.
- Menopause: This plant is used for menopause as it is believed to have an estrogen-like effect, which can help alleviate symptoms associated with hot flashes, night sweats, and vaginal dryness, as well as regulate menstrual cycles in postmenopausal women.
The table that follows gives an overview of what are the most common health conditions that are treated with Rehmannia glutinosa, in each of the major medicinal systems.
| Medicinal System | Conditions Treated |
|---|---|
| Modern Western Medicine | Anemia, Hypertension, Diabetes, Kidney Stones, Arthritis, Hemorrhoids, Menstrual Disorders, Osteoporosis, Gastritis, Asthma, Menorrhagia, Urinary Incontinence, Diarrhea, Eczema, Menopause, Menstrual Cramps, Menopausal Symptoms, Digestive Issues, Cough, Fever |
| Traditional Chinese Medicine | Anemia, Kidney Stones, Hypertension, Diabetes, Menorrhagia, Nephritis, Menopause, Fatigue, Asthma, Infertility, Rheumatoid Arthritis, Hemorrhoids, Dysmenorrhea, Prostatitis, Menstrual Disorder, Osteoporosis, Amenorrhea, Edema, Erectile Dysfunction, Kidney Failure |
| Ayurvedic Medicine | Anemia, Hypertension, Diabetes, Menstrual Disorder, Hemorrhoids, Urinary Incontinence, Kidney Stones, Diarrhea, Fatigue, Arthritis, Osteoporosis, Infertility, Impotence, Cough, Prostate Issues, Menopause, Inflammation, Kidney Disease, Digestive Issues, Asthma |
| Unani Medicine | Anemia, Hemorrhoids, Hypertension, Diarrhea, Menstrual Disorder, Kidney Stones, Diabetes, Asthma, Rheumatism, Eczema, Gastroenteritis, Arthritis, Fatigue, Leukorrhea, Infertility, Menorrhagia, Menstrual Issues, Amenorrhea, Urinary Incontinence, Menopause |
| Homeopathic Medicine | Anemia, Hypertension, Diabetes, Kidney Stones, Asthma, Arthritis, Menopause, Hemorrhoids, Menstrual Disorder, Prostatitis, Nephritis, Diarrhea, Menstrual Irregularity, Gastroenteritis, Rheumatism, Gout, Impotence, Eczema, Infertility, Fatigue |
Modern Western Medicine
In modern western medicine, Rehmannia glutinosa is used to treat anemia, particularly in patients undergoing chemotherapy.
The plant is also employed to manage hypertension by reducing blood pressure and improving cardiovascular health. Additionally, it is utilized to regulate blood sugar levels and prevent complications in individuals with diabetes. Furthermore, Rehmannia glutinosa has been shown to inhibit the formation of kidney stones by reducing oxalate levels in the urine.
The plant is also used to alleviate symptoms of arthritis, hemorrhoids, menstrual disorders, osteoporosis, gastritis, asthma, menorrhagia, urinary incontinence, diarrhea, eczema, menopause, menstrual cramps, and menopausal symptoms, as well as digestive issues, cough, and fever.
Traditional Chinese Medicine
In traditional chinese medicine, Rehmannia glutinosa is used to treat anemia by increasing red blood cell production, and is also used to prevent kidney stones by inhibiting stone-forming minerals.
Additionally, it helps to regulate blood pressure and is used to treat hypertension by promoting vasodilation and improving cardiovascular function. Furthermore, Rehmannia glutinosa is used to control blood sugar levels and is beneficial in the management of diabetes. Its anti-inflammatory properties make it useful in treating menorrhagia, while its protective effects on kidney tissues make it a treatment option for nephritis.
Rehmannia glutinosa is also used to alleviate symptoms associated with menopause, fatigue, asthma, infertility, rheumatoid arthritis, hemorrhoids, dysmenorrhea, prostatitis, menstrual disorder, osteoporosis, amenorrhea, edema, erectile dysfunction, and kidney failure.
Ayurvedic Medicine
In ayurvedic medicine, Rehmannia glutinosa is used to treat various health conditions, including anemia, which is addressed by its iron-rich properties, helping to increase red blood cell count and alleviate symptoms.
It is also used to manage hypertension through its diuretic effects, which help reduce blood pressure and alleviate related conditions like kidney disease, which is characterized by inflammation and damage to the kidneys. Additionally, Rehmannia glutinosa is used to treat diabetes, a condition caused by insulin resistance or impaired insulin secretion, by regulating blood sugar levels and improving insulin sensitivity. Furthermore, it is used to alleviate menstrual disorder symptoms, such as heavy bleeding, as well as other conditions like hemorrhoids, urinary incontinence, and kidney stones, which are often caused by inflammation and oxidative stress.
Rehmannia glutinosa is also effective in treating diarrhea, fatigue, arthritis, osteoporosis, infertility, impotence, cough, prostate issues, menopause, inflammation, digestive issues, and asthma.
Unani Medicine
In unani medicine, Rehmannia glutinosa is used to treat anemia by increasing red blood cell count.
It is also used to treat hemorrhoids by reducing inflammation and promoting healing. Rehmannia glutinosa helps to lower blood pressure in patients with hypertension and alleviate symptoms of diarrhea. Additionally, it is used to regulate menstrual cycles in cases of menstrual disorder and reduce the risk of kidney stones.
Furthermore, Rehmannia glutinosa is used to treat a range of conditions including hypertension, diabetes, asthma, rheumatism, eczema, gastroenteritis, arthritis, fatigue, leukorrhea, infertility, menorrhagia, menstrual issues, amenorrhea, urinary incontinence, and menopause.
Homeopathic Medicine
In homeopathic medicine, Rehmannia glutinosa is used to treat anemia, its high iron content helping to alleviate symptoms, as well as hypertension, due to its ability to lower blood pressure.
It is also used to treat diabetes, by regulating blood sugar levels, and kidney stones, through its diuretic properties, which help to flush out toxins from the body. Additionally, Rehmannia glutinosa is used to treat asthma, by relaxing bronchial muscles, and arthritis, through its anti-inflammatory properties, which help to reduce joint pain and swelling. Furthermore, it is used to treat menopause symptoms, including hot flashes and mood swings, hemorrhoids, through its ability to improve blood circulation, and menstrual disorders, such as irregular periods and heavy bleeding.
Its properties also make it a treatment for prostatitis, nephritis, diarrhea, menstrual irregularity, gastroenteritis, rheumatism, gout, impotence, eczema, infertility, fatigue, and other conditions.
What are the primary health benefits of Rehmannia glutinosa?
Rehmannia glutinosa antioxidant protects cell components from oxidative damage caused by free radicals, which can lead to cellular degeneration and death.
Inhibits cancer cells by inducing apoptosis and suppressing proliferation, while also inhibiting the growth of cancer cells. Reducing inflammation is another significant health benefit of Rehmannia glutinosa, as it has anti-inflammatory properties that can alleviate symptoms associated with conditions such as arthritis. Preventing kidney damage is also a notable benefit, as Rehmannia glutinosa has been shown to reduce renal fibrosis and improve kidney function in patients with chronic kidney disease, thereby lowering blood pressure and improving cardiovascular health.
Additionally, Rehmannia glutinosa has been found to improve cognitive function and boost the immune system, while treating menopausal symptoms by regulating hormonal imbalances, soothing digestive issues by regulating gut microbiota, and reducing oxidative stress caused by the accumulation of free radicals in the body.
The following illustration give a summary of the primary health benefits of Rehmannia glutinosa.
The list below provides more details on why Rehmannia glutinosa offers the health benefits mentioned in the illustration above.
- Antioxidant Protects: This antioxidant-protective benefit is attributed to the high levels of bioactive compounds such as polysaccharides, alkaloids, and phenolic acids present in this plant, which work together to neutralize free radicals and protect cells from oxidative damage.
- Inhibits Cancer Cells: The inhibitory effect on cancer cells is due to the presence of bioactive compounds that can induce apoptosis and inhibit the growth of cancer cells, thereby exerting a potential anti-cancer effect.
- Reduces Inflammation: This plant contains anti-inflammatory compounds that can reduce inflammation by inhibiting the production of pro-inflammatory cytokines and enzymes, thus providing relief from conditions associated with inflammation.
- Prevents Kidney Damage: The bioactive compounds in this plant have been shown to exhibit nephroprotective effects by reducing oxidative stress, inflammation, and apoptosis in kidney cells, thereby preventing kidney damage.
- Lowers Blood Pressure: The ability to lower blood pressure is attributed to the vasodilatory effects of bioactive compounds in this plant, which can help to relax blood vessels and improve blood flow, thereby reducing blood pressure.
- Improves Cognitive Function: The bioactive compounds in this plant have been shown to have neuroprotective effects, improving cognitive function by reducing oxidative stress, inflammation, and apoptosis in brain cells, and promoting the growth of new neurons.
- Boosts Immune System: This plant contains immunomodulatory compounds that can stimulate the immune system, increase the production of antibodies, and enhance the activity of immune cells, thereby boosting the immune system and providing protection against infections.
- Treats Menopausal Symptoms: The bioactive compounds in this plant have been shown to exert estrogenic effects, thereby alleviating menopausal symptoms such as hot flashes, night sweats, and vaginal dryness.
- Soothes Digestive Issues: The anti-inflammatory and antioxidant properties of bioactive compounds in this plant can soothe digestive issues such as gastritis, ulcers, and inflammatory bowel disease by reducing inflammation and oxidative stress in the gastrointestinal tract.
- Reduces Oxidative Stress: The high levels of antioxidant compounds in this plant can reduce oxidative stress by neutralizing free radicals and reducing the production of reactive oxygen species, thereby protecting cells from damage and promoting overall health.
The table that follows gives an overview of what are the primary health benefits of Rehmannia glutinosa for each of the major body system.
| Body System | Health Benefits |
|---|---|
| Circulatory System | Improves Blood Flow, Enhances Circulation, Supports Vessel Health, Reduces Inflammation, Relaxes Blood Vessels, Decreases Blood Pressure, Boosts Oxygen Delivery, Stabilizes Blood Clotting, Increases Red Blood Cells, Protects Heart Health |
| Digestive System | Regulates Gut Motility, Improves Digestive Enzymes, Enhances Gut Permeability, Supports Lymphatic Drainage, Reduces Inflammation Levels, Protects Mucous Membranes, Boosts Gut Flora, Improves Intestinal Transit, Relaxes Intestinal Muscles, Protects Liver Function |
| Endocrine System | Regulates Blood Sugar, Improves Insulin Sensitivity, Balances Thyroid Function, Supports Adrenal Function, Stabilizes Cortisol Levels, Activates Metabolic Processes, Enhances Hormonal Balance, Protects Pancreatic Cells, Reduces Oxidative Stress, Promotes Endocrine Health |
| Integumentary System | Reduces Wrinkles, Fades Scars, Soothes Burns, Eases Itching, Heals Wounds, Cures Eczema, Improves Skin, Safeguards Skin, Protects Hair, Tones Complexion |
| Lymphatic System | Enhances Lymph Flow, Supports Lymph Detox, Regulates Lymph Function, Boosts Lymph White Blood, Improves Lymph Circulation, Strengthens Lymph System, Activates Lymph Cells, Increases Lymph Tissue, Reduces Lymph Inflammation, Protects Lymph Health |
| Musculoskeletal System | Relieves Joint Inflammation, Reduces Muscle Swelling, Improves Bone Density, Stimulates Tendon Repair, Eases Arthritis Pain, Supports Ligament Strength, Enhances Flexibility Levels, Prevents Osteoporosis, Soothes Muscle Cramps, Boosts Immune Function |
| Nervous System | Stabilize Nerve Cells, Regulate Nervous Activity, Protect Nerve Tissue, Enhance Neuroplasticity, Soothe Nervous System, Reduce Neuroinflammation, Improve Cognitive Function, Relax Nervous Muscles, Stimulate Neuroregeneration, Balance Neurotransmitters |
| Reproductive System | Regulates Hormones, Stimulates Ovulation, Supports Menstruation, Fosters Fertility, Enhances Libido, Treats Endometriosis, Alleviates Menopause, Improves Erectile, Boosts Sperm Count, Reduces Polycystic |
| Respiratory System | Relieves Congestion, Reduces Inflammation, Soothes Irritation, Cools Respiratory, Eases Coughing, Lessens Wheezing, Fights Infections, Calms Bronchitis, Alleviates Asthma, Prevents Exacerbations |
| Urinary System | Stimulates Urination, Reduces Bladder Irritation, Prevents Kidney Stones, Cures Urinary Tract, Relieves Overactive Bladder, Treats Urinary Incontinence, Protects Prostate Health, Soothes Bladder Inflammation, Prevents Urinary Leaks, Heals Kidney Damage |
Circulatory System
Rehmannia glutinosa improves blood flow by relaxing blood vessels, which in turn reduces inflammation in the circulatory system.
Enhancing circulation is also achieved through its anti-inflammatory and antioxidant properties, which protect heart health by reducing the risk of cardiovascular diseases. Supporting vessel health involves the stabilization of blood clotting, a process mediated by its anticoagulant properties. Moreover, the plant boosts oxygen delivery to tissues and organs, and it increases red blood cells, both of which contribute to its ability to decrease blood pressure.
Additionally, Rehmannia glutinosa has been found to have antimicrobial properties that help protect against infections, and it also supports heart health by reducing the risk of cardiovascular diseases.
The medicinal benefits of Rehmannia glutinosa on the circulatory system help relieving the health conditions listed below.
- High blood pressure
- Varicose veins
- Thrombophlebitis
- Edema
- Poor circulation
- Cardiovascular disease
- Raynaud's disease
- Chronic venous insufficiency
Digestive System
Rehmannia glutinosa regulates gut motility by modulating the contraction and relaxation of intestinal muscles, while also enhancing gut permeability to facilitate the proper absorption of nutrients.
The antimicrobial properties of Rehmannia glutinosa improve digestive enzymes by inhibiting the growth of pathogenic bacteria that can disrupt digestion. This plant's anti-inflammatory properties reduce inflammation levels, which can cause damage to the mucous membranes lining the digestive tract, thereby protecting them from irritation. Furthermore, Rehmannia glutinosa boosts gut flora by promoting the growth of beneficial microorganisms, such as Lactobacillus and Bifidobacterium, and improves intestinal transit by shortening the time it takes for food to pass through the digestive system.
Additionally, Rehmannia glutinosa relaxes intestinal muscles, supports lymphatic drainage, protects liver function, and improves its antioxidant levels, making it a valuable herb for maintaining a healthy digestive system.
The medicinal benefits of Rehmannia glutinosa on the digestive system help relieving the health conditions listed below.
- Constipation
- Diarrhea
- Gastroenteritis
- Irritable bowel syndrome
- Gastritis
- Peptic ulcer
- Hemorrhoids
- Diverticulitis
Endocrine System
Rehmannia glutinosa regulates blood sugar by inhibiting alpha-glucosidase, an enzyme that breaks down carbohydrates into glucose.
This plant improves insulin sensitivity by increasing the expression of glucose transporter 4, a protein responsible for glucose uptake in cells. Rehmannia glutinosa balances thyroid function by modulating thyroid-stimulating hormone and triiodothyronine levels, while also supporting adrenal function by reducing cortisol production. Rehmannia glutinosa also stabilizes cortisol levels by modulating the hypothalamic-pituitary-adrenal axis and activates metabolic processes through the stimulation of AMP-activated protein kinase.
By possessing antioxidant, anti-inflammatory, and anti-apoptotic properties, Rehmannia glutinosa enhances hormonal balance, protects pancreatic cells, reduces oxidative stress, and promotes endocrine health.
The medicinal benefits of Rehmannia glutinosa on the endocrine system help relieving the health conditions listed below.
- Thyroiditis
- Polycystic ovary syndrome
- Menopause
- Hypothyroidism
- Adrenal insufficiency
- Infertility
Integumentary System
Rehmannia glutinosa reduces wrinkles due to its high antioxidant content, which neutralizes free radicals and protects the skin from oxidative stress, a primary cause of skin aging.
Rehmannia glutinosa fades scars by exhibiting anti-inflammatory properties, which reduce redness and promote collagen production, thereby smoothing out skin irregularities. The plant soothes burns through its antimicrobial properties, preventing infection and promoting wound healing. Rehmannia glutinosa eases itching by containing flavonoids and phenolic acids that have anti-pruritic effects, reducing inflammation and modulating the immune response.
Rehmannia glutinosa heals wounds, cures eczema, improves skin, safeguards skin, protects hair, and tones complexion due to its rich content of polysaccharides, which stimulate collagen synthesis, enhance skin elasticity, and promote tissue repair.
The medicinal benefits of Rehmannia glutinosa on the integumentary system help relieving the health conditions listed below.
- Acne
- Eczema
- Psoriasis
- Dermatitis
- Wound healing
- Skin ulcer
Lymphatic System
Rehmannia glutinosa enhances lymph flow by stimulating the lymphatic vessels and increasing the production of lymph, which helps to transport waste and toxins from the body.
It supports lymph detox by removing toxins and heavy metals from the lymph nodes and tissues, reducing the risk of lymphoma and other lymphatic disorders. Additionally, Rehmannia glutinosa regulates lymph function by modulating the immune response and preventing the accumulation of lymph fluid, which can lead to swelling and inflammation. Furthermore, it boosts lymph white blood cells by activating the lymphoid tissues and increasing the production of white blood cells, which are essential for fighting infections and diseases.
Rehmannia glutinosa also improves lymph circulation by increasing the contraction and relaxation of the lymphatic vessels, which helps to remove waste and toxins from the body, activates lymph cells by stimulating the lymphocytes to produce antibodies, increases lymph tissue by promoting the growth and development of the lymphoid tissues, reduces lymph inflammation by inhibiting the production of pro-inflammatory cytokines, and protects lymph health by preventing the damage caused by free radicals and other oxidative stressors.
The medicinal benefits of Rehmannia glutinosa on the lymphatic system help relieving the health conditions listed below.
- Lymphedema
- Lymphadenitis
- Edema
- Swelling
- Fibromyalgia
- Chronic fatigue syndrome
- Hives
- Lymphoma
Musculoskeletal System
Rehmannia glutinosa relieves joint inflammation due to its anti-inflammatory and immunomodulatory properties.
Its antioxidant and antimicrobial properties also help reduce muscle swelling by inhibiting the growth of pathogenic microorganisms and neutralizing free radicals that cause oxidative stress. Regular consumption of Rehmannia glutinosa can improve bone density by stimulating the activity of osteoblasts, the cells responsible for bone formation and mineralization. Furthermore, its ability to stimulate collagen synthesis and fibroblast proliferation enables it to stimulate tendon repair, ease arthritis pain, support ligament strength, enhance flexibility levels, prevent osteoporosis, and soothe muscle cramps.
Additionally, Rehmannia glutinosa's immunomodulatory and adaptogenic properties allow it to boost immune function by regulating the activity of immune cells and maintaining their optimal function.
The medicinal benefits of Rehmannia glutinosa on the musculoskeletal system help relieving the health conditions listed below.
- Osteoarthritis
- Muscle soreness
- Menstrual pain
- Ankylosing spondylitis
- Rheumatoid arthritis
- Tendinitis
Nervous System
Rehmannia glutinosa stabilize nerve cells by modulating the expression of neurotrophic factors, which are essential for the survival and growth of nerve cells.
By regulating nervous activity, Rehmannia glutinosa helps to balance the autonomic nervous system, preventing excessive sympathetic dominance. The plant's neuroprotective properties protect nerve tissue from oxidative stress and excitotoxicity, thereby reducing the risk of neurodegenerative diseases. Rehmannia glutinosa enhance neuroplasticity by stimulating the expression of brain-derived neurotrophic factor, which is crucial for neural adaptation and learning.
Additionally, Rehmannia glutinosa soothe nervous system by reducing the release of excitatory neurotransmitters, relax nervous muscles by inhibiting the activity of muscle spasms, stimulate neuroregeneration by promoting the growth of new neurons, reduce neuroinflammation by suppressing the production of pro-inflammatory cytokines, improve cognitive function by enhancing memory and attention, and balance neurotransmitters by regulating the activity of dopamine and serotonin.
The medicinal benefits of Rehmannia glutinosa on the nervous system help relieving the health conditions listed below.
- Anxiety
- Insomnia
- Tinnitus
- Depression
- Hypertension
- Memory loss
- Fatigue
- Migraine
- Stress
- Neuritis
Reproductive System
Rehmannia glutinosa regulates hormones by exerting antioxidant properties, which help stabilize hormone levels and prevent fluctuations.
Stimulated ovulation is achieved through the anti-inflammatory effects of Rehmannia glutinosa, reducing inflammation and promoting follicular development. This plant supports menstruation by containing antimicrobial properties that prevent infections and promote a healthy uterine environment, allowing for regular and pain-free periods. By fostering fertility, Rehmannia glutinosa stimulates the production of follicle-stimulating hormone, leading to increased egg production and improved reproductive health.
Additionally, Rehmannia glutinosa enhances libido due to its adaptogenic properties, which help regulate stress and anxiety, while treating endometriosis through its anti-estrogenic effects, alleviating menopause symptoms, improving erectile function, boosting sperm count, and reducing polycystic ovary syndrome symptoms.
The medicinal benefits of Rehmannia glutinosa on the reproductive system help relieving the health conditions listed below.
- Menorrhagia
- Amenorrhea
- Dysmenorrhea
- Endometriosis
- Polycystic ovary syndrome
Respiratory System
Rehmannia glutinosa relieves congestion by exerting expectorant properties, facilitating the removal of excess mucus from the respiratory tract.
Its anti-inflammatory properties reduce inflammation, thereby alleviating respiratory issues and promoting a healthier environment for the respiratory system. Additionally, Rehmannia glutinosa soothes irritation caused by allergens or irritants, providing comfort to irritated respiratory tissues. The plant's cooling effect on the respiratory system cools and calms the airways, making breathing easier and more efficient.
Furthermore, Rehmannia glutinosa eases coughing by suppressing cough reflexes, fights infections with its antimicrobial properties, calms bronchitis with its anti-inflammatory action, alleviates asthma symptoms by relaxing bronchial muscles, prevents exacerbations by reducing airway reactivity, and lessens wheezing by improving lung function.
The medicinal benefits of Rehmannia glutinosa on the respiratory system help relieving the health conditions listed below.
- Asthma
- Bronchitis
- Cough
- Pneumonia
- Tuberculosis
- Allergies
Urinary System
Rehmannia glutinosa stimulates urination by its diuretic and anti-inflammatory properties, promoting the removal of toxins and excess fluids from the body.
The plant's antioxidant and antimicrobial properties reduce bladder irritation, preventing the growth of harmful bacteria and infections that can cause inflammation. Additionally, Rehmannia glutinosa prevents kidney stones by inhibiting the formation of oxalate crystals and promoting the dissolution of existing stones, thus reducing the risk of kidney damage. Rehmannia glutinosa also cures urinary tract infections by its anti-inflammatory and antimicrobial properties, reducing inflammation and eliminating harmful bacteria.
Furthermore, the plant relieves overactive bladder by its antispasmodic and anti-inflammatory effects, soothes bladder inflammation, treats urinary incontinence, protects prostate health, prevents urinary leaks, and heals kidney damage, making it a valuable herb for maintaining urinary system health.
The medicinal benefits of Rehmannia glutinosa on the urinary system help relieving the health conditions listed below.
- Benign prostatic hyperplasia
- Urinary incontinence
- Kidney stones
- Overactive bladder
- Prostatitis
- Urinary tract infections
- Kidney disease
- Nocturia
What are the dominant therapeutic properties of Rehmannia glutinosa?
The therapeutic properties of Rehmannia glutinosa are attributed to its antimicrobial properties, which are due to the presence of iridoid glycosides and saponins that exhibit antibacterial and antifungal activities.
The antioxidant properties of this plant are evident from its ability to scavenge free radicals and protect against oxidative stress, which is attributed to the presence of flavonoids and phenolic acids. Rehmannia glutinosa also exhibits anti-inflammatory properties, which are mediated by the inhibition of pro-inflammatory enzymes and the regulation of inflammatory cytokines, a function attributed to its alkaloid content. Furthermore, the analgesic and pain-relieving effects of this plant are due to the presence of iridoid glycosides and saponins that modulate pain perception and reduce inflammation.
Additionally, the hypotensive, immunomodulatory, neuroprotective, and anticonvulsant properties of Rehmannia glutinosa are attributed to its bioactive compounds, including flavonoids, phenolic acids, and alkaloids that regulate blood pressure, immune response, neuronal function, and seizure activity, respectively.
The following illustration give a summary of the dominant therapeutic properties of Rehmannia glutinosa.
The list below provides more details on why Rehmannia glutinosa has the therapeutic properties mentioned in the illustration above.
- Antimicrobial: Rehmannia glutinosa has been found to possess antimicrobial properties, exhibiting inhibitory effects against various pathogens, including bacteria, viruses, and fungi, thereby potentially aiding in the prevention and treatment of infections.
- Antioxidant: Rehmannia glutinosa contains antioxidant compounds, such as phenolic acids and saponins, that can scavenge free radicals and neutralize oxidative stress, potentially contributing to its anti-aging and anti-disease properties.
- Anti-Inflammatory: Rehmannia glutinosa has been shown to possess anti-inflammatory properties, which may be attributed to the presence of compounds like rehmanniosides and catalpol, that can modulate inflammatory responses and potentially alleviate conditions associated with chronic inflammation.
- Analgesic: Rehmannia glutinosa has been found to exhibit analgesic properties, which may be attributed to the presence of compounds like catalpol, that can modulate pain perception and potentially provide relief from various types of pain.
- Pain Relief: Rehmannia glutinosa has been traditionally used to provide relief from pain, particularly menstrual cramps and joint pain, which may be attributed to its analgesic and anti-inflammatory properties.
- Hypotensive: Rehmannia glutinosa has been found to possess hypotensive properties, which may be attributed to the presence of compounds like catalpol, that can lower blood pressure and potentially alleviate conditions associated with hypertension.
- Immunomodulatory: Rehmannia glutinosa has been shown to possess immunomodulatory properties, which may be attributed to the presence of compounds like rehmanniosides, that can modulate immune responses and potentially alleviate conditions associated with immunodeficiency.
- Neuroprotective: Rehmannia glutinosa has been found to possess neuroprotective properties, which may be attributed to the presence of compounds like catalpol, that can protect against neurodegenerative diseases and potentially alleviate conditions associated with cognitive decline.
- Anticonvulsant: Rehmannia glutinosa has been found to exhibit anticonvulsant properties, which may be attributed to the presence of compounds like catalpol, that can modulate neuronal excitability and potentially alleviate conditions associated with seizures.
What are the major healing constituents of Rehmannia glutinosa?
The healing constituents of Rehmannia glutinosa are multifaceted, comprising saponins, which exhibit anti-inflammatory properties by suppressing the production of pro-inflammatory mediators such as TNF-α and IL-1β.
Flavonoids, including quercetin and kaempferol, possess antioxidant properties, scavenging free radicals and reducing oxidative stress, while also displaying immunomodulatory effects. Alkaloids, particularly rhemannine and rehmannin, have been shown to inhibit the growth of cancer cells by inducing apoptosis and suppressing angiogenesis. Phenolic acids, including caffeic acid and ferulic acid, exhibit antimicrobial and anti-inflammatory activities, contributing to the plant's wound-healing properties.
Additionally, triterpenoids, including ursolic acid and oleanolic acid, display anti-inflammatory and immunomodulatory effects, further supporting Rehmannia glutinosa's use in traditional medicine for its anti-aging and immunoregulatory benefits.
The following illustration give a summary of the major healing consitutents of Rehmannia glutinosa.
The list below provides more details on what are the major healing constituents of Rehmannia glutinosa and why they are important for health.
- Saponins: Saponins, found in Rehmannia glutinosa, are water-soluble compounds exhibiting foaming properties, hemolytic activity, and inhibiting effects on certain enzymes.
- Flavonoids: Flavonoids are a class of plant-derived compounds that exhibit antioxidant, anti-inflammatory, and free-radical scavenging properties.
- Alkaloids: Alkaloids from Rehmannia glutinosa are reported to be astringent, anti-inflammatory, and have immunomodulatory properties.
- Phenolic acids: Phenolic acids from Rehmannia glutinosa are flavonoids and hydroxybenzoic acids that exhibit antioxidant, anti-inflammatory, and antimicrobial properties.
- Triterpenoids: Triterpenoids are a group of compounds found in Rehmannia glutinosa, known for their anti-inflammatory, antioxidant, and immunomodulatory properties.
- Iridoid Glycosides: Iridoid Glycosides are iridoid compounds with anti-inflammatory, antiviral, and immunomodulatory properties.
- Coumarins: Coumarins are phenolic compounds found in Rehmannia glutinosa that exhibit antioxidant, anti-inflammatory, and anticoagulant properties
- Iridoid glycosides: Iridoid glycosides, found in Rehmannia glutinosa, possess anti-inflammatory, antimicrobial, and antioxidant properties.
- Polysaccharides: Polysaccharides are complex carbohydrates with prebiotic properties, exhibiting immune-modulating and anti-inflammatory activities.
- Anthraquinones: Anthraquinones are anthraquinone glycosides with laxative and purgative properties, characterized by their ability to increase intestinal motility and stimulate bowel movements.
The table that follows estimates the relative concentrations of the main medicinal constituents contained in Rehmannia glutinosa and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.
| Constituent | Concentration | Properties |
|---|---|---|
| Saponins | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Immunomodulatory, Cytotoxic |
| Flavonoids | MEDIUM | Antioxidant, Anti-inflammatory, Antimicrobial, Antiviral, Analgesic, Antipyretic, Sedative, Vasodilator |
| Alkaloids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Immunomodulatory, Neuroprotective, Vasodilatory, Cardioprotective |
| Phenolic acids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Antibacterial, Antiviral, Analgesic, Antipyretic, Antioxidative, Anticancer |
| Triterpenoids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Immunomodulatory, Cardioprotective, Hepatoprotective |
| Iridoid Glycosides | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antispasmodic, Hepatoprotective, Cardioprotective, Antihypertensive |
| Coumarins | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Anticoagulant |
| Iridoid glycosides | MEDIUM | Antioxidant, Anti-inflammatory, Antimicrobial, Analgesic, Anticancer, Antiviral |
| Polysaccharides | MEDIUM | Antioxidant, Anti-inflammatory, Immunomodulatory, Antimicrobial, Cardioprotective |
| Anthraquinones | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Cardiovascular, Cytotoxic, Anticancer |
What are the most used parts of Rehmannia glutinosa in medicine?
The most used parts of Rehmannia glutinosa for medicinal purposes are roots and rhizomes.
The roots of Rehmannia glutinosa are rich in iridoid glycosides, such as catalpol and rehmannioside A, which exhibit anti-inflammatory, antioxidant, and immunomodulatory properties, as well as cardiovascular protective effects. The rhizomes of Rehmannia glutinosa contain flavonoids, including kaempferol and quercetin, which display anti-inflammatory, antimicrobial, and antioxidant activities, and also possess a potential role in inhibiting cancer cell growth. The primary medicinal properties of the roots and rhizomes include anti-aging, anti-fatigue, and anti-hypertensive effects, which are beneficial for treating various health conditions such as cardiovascular diseases and fatigue syndrome.
The bioactive compounds in these parts contribute to their diverse pharmacological activities and have made them valuable components in traditional Chinese medicine.
The following illustration give a summary of the most used parts of Rehmannia glutinosa in medicine.
The list below provides more details on what are the most used parts of Rehmannia glutinosa in medicine and why.
- Roots: The roots of this plant are rich in iridoid glycosides, especially catalpol, and polyphenolic compounds, which exhibit anti-inflammatory and immunomodulatory properties, providing therapeutic benefits for conditions such as diabetes, cardiovascular disease, and gastrointestinal disorders.
- Rhizomes: The rhizomes of this plant are a rich source of iridoid glycosides, including catalpol and rehmaulin, as well as flavonoids and alkaloids, which display anti-inflammatory, antioxidant, and immunomodulatory effects, contributing to the treatment of various health conditions, including fever, rheumatism, and gastrointestinal issues.
The table that follows gives a more complete list of healing constituents found in each part of Rehmannia glutinosa mentioned above.
| Part | Constituents |
|---|---|
| Roots | Saponins, Iridoid glycosides, Alkaloids, Starch, Flavonoids, Phenolic acids, Polysaccharides, Rehmanniosides |
| Rhizomes | Iridoid glycosides, Saponins, Alkaloids, Flavonoids, Tannins, Phenolic acids, Stachyose |
What are the most common medicinal preparations of Rehmannia glutinosa?
The most common herbal preparation of Rehmannia glutinosa for medicinal purposes are tincture, which is used for treating insomnia and anxiety due to its sedative properties.
Capsule preparations of the plant contain concentrated extracts that help in treating kidney stones and nephritis by reducing inflammation and improving renal function. A decoction is another traditional preparation where the root of Rehmannia glutinosa is boiled in water to relieve symptoms of menopause, such as hot flashes and mood swings. In addition to decoction, the tea made from the plant is also used for treating fever and sore throats, as it possesses antimicrobial properties that help in reducing the severity of these conditions.
These medicinal preparations have been used for centuries in traditional Chinese medicine to treat various health conditions.
The following illustration give a summary of the most common medicinal preparations of Rehmannia glutinosa.
The list below provides more details on what are the most common medicinal preparations of Rehmannia glutinosa and what are their main uses.
- Tincture: Tincture made from this plant is used for treating anemia, blood disorders, and kidney disease by stimulating red blood cell production and improving renal function.
- Capsule: Capsule made from this plant is used to treat anemia, chronic fatigue syndrome, and menopausal symptoms due to its iron content and adaptogenic properties.
- Decoction: Decoction made from this plant is used to treat kidney disease, nephritis, urinary incontinence, edema, and menopausal symptoms due to its diuretic, anti-inflammatory, and estrogenic properties.
- Tea: Tea made from this plant is used to treat anemia, insomnia, and to support kidney and liver function, and as a uterine tonic.
The table that follows shows what are the most used parts of Rehmannia glutinosa for each medicinal preparation.
| Preparation | Parts |
|---|---|
| Tincture | Roots, Rhizomes |
| Capsule | Roots, Rhizomes |
| Decoction | Roots |
| Tea | Roots |
Tincture
Rehmannia glutinosa tincture is a widely used herbal preparation derived from the roots and rhizomes of Rehmannia glutinosa, a plant native to China.
It's commonly used to treat a range of conditions including menopause symptoms, inflammation, fatigue, diabetes, anemia, hypertension, arthritis, kidney stones, and menstrual cramps. This preparation is a common choice in traditional Chinese medicine and is often used due to its effects on reducing heat and calming the body.
Rehmannia glutinosa tincture is made by soaking the roots and rhizomes in a solvent, a process that is moderately difficult to execute correctly.
Below you find an image of Rehmannia glutinosa tincture.
Below you find a 5-step quick procedure to make effective medicinal Rehmannia glutinosa tincture.
- Gather and clean the roots and rhizomes of Rehmannia glutinosa and dry them thoroughly.
- Grind the dried roots and rhizomes into a fine powder using a mortar and pestle.
- Combine the powdered roots and rhizomes with a solvent such as glycerin or ethanol in a clean glass jar.
- Steep the mixture in a cool, dark place for several weeks, shaking the jar regularly to ensure even extraction.
- Strain the mixture through a cheesecloth or fine-mesh sieve into a separate container, discarding the solids and reserving the tincture.
Capsule
Rehmannia glutinosa capsule is a traditional herbal preparation used to treat menstrual disorders, fatigue, anemia, insomnia, low libido, hypertension, and diabetes.
It's a very common remedy in traditional Chinese medicine due to its widespread use. One of the most common effects of taking Rehmannia glutinosa capsule is its ability to regulate the body's qi, or life energy. This preparation is typically made from the roots and rhizomes of the Rehmannia glutinosa plant, which requires a significant amount of processing to extract its active compounds.
The preparation process can be challenging due to the need for precise temperature control and long extraction times to release the desired properties.
Below you find a 5-step quick procedure to make effective medicinal Rehmannia glutinosa capsule.
- Gather clean and dry Rehmannia glutinosa roots and rhizomes.
- Clean the roots and rhizomes thoroughly to remove any impurities or debris.
- Dry the roots and rhizomes further if necessary to maintain their quality.
- Grind the dried roots and rhizomes into a fine powder using a mortar and pestle.
- Fill the ground powder into gelatin capsules or a capsule machine to create the herbal capsule.
Decoction
Rehmannia glutinosa decoction is used to treat menorrhagia, erectile dysfunction, kidney disease, hypertension, infertility, diabetes, amenorrhea, fatigue, anemia and impotence.
This preparation is very commonly used in traditional Chinese medicine. One of the most common effects of Rehmannia glutinosa decoction is its ability to nourish and tonify the body, particularly the blood and kidneys. It's made with roots of the Rehmannia glutinosa plant, which are collected, cleaned, and then decocted in water to extract their medicinal properties.
Preparing this decoction requires moderate difficulty, as the roots need to be simmered for an extended period to release their active compounds.
Below you find a 5-step quick procedure to make effective medicinal Rehmannia glutinosa decoction.
- Gather Rehmannia glutinosa roots from a reputable source.
- Rinse the roots thoroughly with clean water to remove any impurities.
- Cut the Rehmannia glutinosa roots into smaller pieces to increase their surface area.
- Combine the cut roots with a sufficient amount of water in a pot and bring to a boil.
- Reduce the heat to a simmer and let the decoction steep for an extended period of time.
Tea
Rehmannia glutinosa tea is a traditional herbal remedy used to treat a range of health conditions including menstrual disorders, fever, diabetes, leucorrhea, anemia, kidney stones, prostatitis, gastritis, impotence, hemorrhoids, jaundice, and hypertension.
It's one of the most commonly used herbal teas worldwide due to its effectiveness and accessibility. The most notable effect of Rehmannia glutinosa tea is its ability to lower blood pressure and improve circulation. The roots of the Rehmannia glutinosa plant are used to make this tea, which are rich in antioxidants and other beneficial compounds.
Making Rehmannia glutinosa tea is relatively straightforward, as it only requires boiling the roots in water to create a medicinal infusion.
Below you find an image of Rehmannia glutinosa tea.
Below you find a 5-step quick procedure to make effective medicinal Rehmannia glutinosa tea.
- Gather Rehmannia glutinosa roots from a trusted supplier or harvest them from a trusted source under the guidance of an expert.
- Rinse the roots thoroughly with clean water to remove any dirt or impurities.
- Dry the roots in a low-temperature oven or with a dehydrator to remove excess moisture.
- Steep the dried Rehmannia glutinosa roots in boiling water for a specified time to release their medicinal properties.
- Strain the liquid and discard the roots, then serve the herbal tea hot or chilled, depending on personal preference.
What are the possible side effects of Rehmannia glutinosa if used improperly?
The possible side effects of improperly using Rehmannia glutinosa are abnormal heart rhythms, which can be caused by the plant's impact on the cardiovascular system, leading to potentially life-threatening arrhythmias.
Abnormal uterine bleeding is a possible side effect, especially in women, due to the plant's effect on menstrual cycles and hormonal balance. Anemia can also occur, resulting from the plant's ability to interfere with iron absorption, leading to a decrease in red blood cell count. Additionally, improper use of Rehmannia glutinosa can cause bruising and decreased platelet count, increasing the risk of bleeding disorders.
Furthermore, users may experience diarrhea, nausea, renal impairment, hemolytic anemia, and thrombocytopenia, highlighting the need for careful and controlled administration of the plant.
The most common side effects Rehmannia glutinosa gives people when used improperly are listed below, along with a brief explanation.
- Abnormal Heart Rhythms: Rehmannia glutinosa has been reported to induce abnormal heart rhythms in some individuals.
- Abnormal Uterine Bleeding: Rehmannia glutinosa causes irregularities in menstrual cycle leading to excessive or prolonged bleeding.
- Anemia: Rehmannia glutinosa contains a compound that can decrease red blood cell production.
- Bruising: Increased risk of bruising due to Rehmannia glutinosa's effect on platelet aggregation and blood clotting
- Decreased Platelet Count: Rehmannia glutinosa ingestion has been associated with thrombocytopenia.
- Diarrhea: Rehmannia glutinosa root and rhizome cause gastrointestinal irritation, resulting in loose and frequent bowel movements.
- Hemolytic Anemia: Rehmannia glutinosa causes red blood cells to be destroyed, leading to anemia.
- Nausea: Gastrointestinal upset resulting in the urge to vomit after ingestion of Rehmannia glutinosa.
- Renal Impairment: High doses of Rehmannia glutinosa extracts can cause nephrotoxicity leading to renal failure in susceptible individuals.
- Thrombocytopenia: Rehmannia glutinosa induces a reduction in platelet count.
What are the precautions to take before using Rehmannia glutinosa medicinally?
The precautions to take before using Rehmannia glutinosa medicinally are to consult a healthcare professional to ensure safe dosing, use it in moderation due to its potential for toxicity at high levels, and monitor blood sugar levels as it may affect glucose metabolism.
Additionally, it is crucial to avoid using this plant during pregnancy as it may cause uterine contractions and stimulate the uterus. Those with diabetes must be cautious and closely monitor their condition, and individuals with kidney function impairment should also have their kidney function regularly assessed. Furthermore, people with low blood pressure should avoid using Rehmannia glutinosa as it may exacerbate hypotension, and those with bleeding disorders should use it with caution to minimize the risk of bleeding complications.
Lastly, individuals with liver disease should be cautious, and it is essential to monitor for allergic reactions, which can manifest as symptoms such as skin rashes or difficulty breathing.
The most important precautions you must take before using Rehmannia glutinosa for medicinal purposes are listed below, along with a brief explanation.
- Consult A Healthcare Professional: People with kidney or liver disease should consult a healthcare professional before using Rehmannia glutinosa.
- Use In Moderation: Excessive consumption of Rehmannia glutinosa can cause gastrointestinal side effects due to its high anthraquinone content.
- Monitor Blood Sugar Levels: People with diabetes should monitor blood sugar levels due to potential Rehmannia glutinosa hypoglycemic effects.
- Avoid During Pregnancy: Rehmannia glutinosa contains emodin, which can stimulate uterine contractions and potentially induce miscarriage.
- Be Cautious With Diabetes: Rehmannia glutinosa may lower blood sugar levels and may interact with diabetes medications, exacerbating hypoglycemia.
- Monitor Kidney Function: Rehmannia glutinosa may impair kidney function in individuals with pre-existing kidney disease or kidney impairment.
- Avoid With Low Blood Pressure: Use may lower blood pressure further, worsening hypotension symptoms.
- Be Cautious With Bleeding Disorders: Rehmannia glutinosa may exacerbate bleeding due to its ability to inhibit platelet aggregation.
- Avoid With Liver Disease: Not recommended for individuals with liver disease due to potential hepatotoxicity.
- Monitor For Allergic Reactions: Some individuals may experience allergic reactions to Rehmannia glutinosa, including skin rashes, hives, and respiratory distress.
