Updated: 1 20, 2025
Rehmannia glutinosa
Table of Contents
What is Rehmannia glutinosa?
Rehmannia glutinosa is a perennial herbaceous plant that belongs to the family Plantaginaceae.
It has a thick, fleshy rootstock and a taproot, which grows up to 5 cm in diameter, with a fibrous and reticulated rhizome. The stem is erect, 30-100 cm tall, with a simple or branched inflorescence and a green, lanceolate or ovate leaf. The flowers are purple, in a raceme or a spike, 5-20 cm long, with a tubular corolla and 5 lobes, and are fertile.
The plant produces small, brown seeds, 3-5 mm long, in a capsule.
What ailments can you heal with this herb?
The most common ailments you can heal with Rehmannia glutinosa are anemia due to its high iron content, hypertension through its ability to lower blood pressure, and digestive issues such as diarrhea and eczema due to its anti-inflammatory properties.
Additionally, Rehmannia glutinosa is used to treat kidney disease and kidney stones by reducing the formation of oxalate stones, menstrual irregularity by balancing the menstrual cycle, and osteoporosis through its ability to increase bone density. It is also used to alleviate arthritis and rheumatoid arthritis symptoms, as well as to treat asthma and inflammation by reducing the production of pro-inflammatory cytokines. Furthermore, Rehmannia glutinosa is used to treat menopause symptoms, menstrual disorder, and urinary incontinence by regulating hormone levels and improving bladder control.
It also has antiseptic properties that help to treat hemorrhoids, reduce fatigue by increasing energy levels, and alleviate migraine symptoms through its ability to relax blood vessels.
What are the therapeutic properties this herb?
The main therapeutic properties of Rehmannia glutinosa are antioxidant, which is attributed to its content of flavonoids, helping to neutralize free radicals and protect cells from oxidative damage.
As an anti-inflammatory, this plant has been shown to inhibit the production of pro-inflammatory cytokines, thereby reducing inflammation and alleviating symptoms associated with various diseases. The cardioprotective effects of Rehmannia glutinosa have been linked to its ability to scavenge free radicals and modulate the cardiovascular system, contributing to the prevention of atherosclerosis and cardiac arrhythmias. Additionally, this plant exhibits neuroprotective properties, with saponins and other bioactive compounds displaying neurotrophic and anti-apoptotic activities that may help in the treatment of neurodegenerative diseases.
Its antimicrobial properties are also noteworthy, with volatile oils and other compounds exhibiting antimicrobial activities against a range of pathogens, including bacteria, fungi, and viruses.
What are the medicinal constituents this herb?
The most important healing constituents of Rehmannia glutinosa are a group of iridoid glycosides known as rehmanniosides, which include rehmannioside A, rehmannioside B, rehmannioside C, rehmannioside D, and rehmannioside E. These compounds have been shown to possess anti-inflammatory, antioxidant, and immunomodulatory activities, contributing to the herb's traditional use in treating various diseases.
Rehmannioside A has been found to inhibit the production of pro-inflammatory cytokines, while rehmannioside B has been reported to exhibit antioxidant and free radical scavenging activities. Rehmannioside C has been shown to possess immunomodulatory effects by regulating the activity of immune cells, and rehmannioside D has been found to inhibit the expression of inflammatory genes.
Rehmannioside E has been reported to exhibit anti-inflammatory and antioxidant activities, and to possess a protective effect on the liver.
What are the main herbal preparations this herb?
The main herbal preparations of Rehmannia glutinosa are used to nourish the kidneys and tonify the blood, particularly in the treatment of deficiency patterns such as blood deficiency, kidney deficiency and yin deficiency.
Liu wei dihuang wan is a classic formulation that combines Rehmannia glutinosa with other herbs to nourish the kidney and tonify the blood, while dang gui si ni tang is used to treat blood deficiency with amenorrhea or irregular menstruation by combining Rehmannia glutinosa with angelica and other herbs. Liu jun zi tang is another formulation that combines Rehmannia glutinosa with other herbs to tonify the kidney and promote urination, while sheng di huang tang is used to treat deficiency patterns with excessive sweating and night sweating. Si wu tang is a classic formulation that combines Rehmannia glutinosa with four other herbs to tonify the blood and nourish the liver and kidneys.
These preparations are commonly used in traditional Chinese medicine to treat various deficiency patterns and promote overall health and well-being.
What are the possible side effects of using this herb improperly?
The possible side effects of using Rehmannia glutinosa are numerous and potentially severe when used improperly.
Nausea is a common side effect due to its high content of iridoid glycosides and anthraquinones, which can cause gastrointestinal irritation and vomiting. Repeated use of Rehmannia glutinosa can exacerbate kidney damage in individuals with pre-existing kidney issues, as its saponins and glycosides can increase the risk of nephrotoxicity. Additionally, Rehmannia glutinosa can increase blood pressure and worsen anemia in individuals with hypertension or anemia, due to its ability to stimulate the sympathetic nervous system and reduce iron absorption.
Furthermore, Rehmannia glutinosa can cause diarrhea in some individuals, potentially due to its laxative properties and irritation of the intestinal mucosa.