10 Possible Side Effects Of Pueraria Mirifica (Kwao Krua)

Pueraria mirifica has some side effects when used improperly, such as allergic reactions, digestive issues, and hormonal imbalances.

These side effects can occur due to overconsumption or interactions with other medications. For instance, excessive use of Pueraria mirifica can lead to estrogen dominance, causing symptoms like bloating, mood swings, and breast tenderness.

This can worsen lives by disrupting daily routines and straining relationships.

This article explains in details the 10 most common side effects of Pueraria mirifica if used imporperly.

1. Triggers anxiety attacks

Pueraria mirifica causes allergic reactions.

This is due to the plant's high concentration of isoflavones and saponins, which can trigger an immune response in some individuals. The allergenic compounds can bind to immunoglobulin E (IgE) antibodies, leading to the release of histamine and other chemicals that cause symptoms such as hives, itching, and swelling.

In severe cases, allergic reactions can progress to anaphylaxis, a life-threatening condition requiring immediate medical attention.

2. Triggers anxiety attacks

Pueraria mirifica triggers estrogen dominance when used, likely due to its high content of isoflavones and other plant compounds that mimic the effects of estrogen in the body.

This can lead to an imbalance of estrogen levels, causing a range of side effects including breast tenderness, mood swings, and changes in menstrual cycles.

The exact mechanisms behind this effect are not fully understood, but it is thought to be related to the way Pueraria mirifica interacts with estrogen receptors in the body.

3. Triggers anxiety attacks

Pueraria mirifica increases blood pressure due to its unique phytochemical composition.

The plant's isoflavones and saponins can stimulate the body's production of adrenaline, leading to increased cardiac output and elevated blood pressure. Additionally, Pueraria mirifica has been found to cause vasoconstriction, which further contributes to hypertension.

These effects are thought to be responsible for the blood pressure increase experienced by some individuals using the herb.

4. Triggers anxiety attacks

Pueraria mirifica lowers blood sugar levels by stimulating insulin production and improving glucose uptake in the body.

This is due to its ability to activate certain enzymes involved in glucose metabolism, such as AMP-activated protein kinase (AMPK). Additionally, Pueraria mirifica has been shown to decrease gluconeogenesis, a process that generates new glucose molecules from non-carbohydrate sources.

These mechanisms contribute to reduced blood sugar levels, potentially affecting individuals with diabetes or those taking medications for blood sugar control.

5. Triggers anxiety attacks

Pueraria mirifica affects liver function due to its ability to stimulate estrogen receptors and alter hormone levels.

The phytoestrogens present in the plant can cause an increase in estrogen production, which may lead to changes in liver enzyme activity and potentially interfere with liver function.

Additionally, Pueraria mirifica's potential to enhance the metabolism of certain medications may also contribute to liver function abnormalities.

6. Triggers anxiety attacks

Pueraria mirifica stimulates uterine contractions due to its ability to mimic the effects of estrogen in the body.

The plant contains phytoestrogens, which are natural compounds that can bind to estrogen receptors and trigger a response similar to that of endogenous estrogen.

This can lead to increased muscle tone and contraction in the uterus, potentially causing side effects such as cramping, spotting, or even premature labor.

7. Triggers anxiety attacks

Pueraria mirifica interferes with thyroid function due to its ability to stimulate the production of thyroid hormones.

This can lead to an imbalance in thyroid levels, causing symptoms such as rapid or irregular heartbeat, weight loss or gain, and fatigue.

Additionally, Pueraria mirifica's estrogen-like properties may also disrupt thyroid hormone regulation, exacerbating this side effect.

8. Triggers anxiety attacks

Pueraria mirifica disrupts menstrual cycles due to its phytoestrogenic properties, which can mimic the effects of estrogen in the body.

The plant's isoflavones and saponins can bind to estrogen receptors, leading to an imbalance of estrogen levels and irregular menstrual patterns.

This disruption can cause changes in the duration, frequency, or even complete cessation of menstruation, potentially affecting fertility and overall reproductive health.

9. Triggers anxiety attacks

Pueraria mirifica causes breast tenderness due to its high content of isoflavones and other phytochemicals.

These compounds mimic the effects of estrogen in the body, leading to an increase in estrogen receptors in breast tissue. This can cause breast swelling, tenderness, and discomfort, particularly during the first few weeks of using the herb.

As a result, some women may experience breast soreness or pain while taking Pueraria mirifica supplements.

10. Triggers anxiety attacks

Pueraria mirifica induces uterine bleeding due to its high content of phytoestrogens, which mimic the effects of estrogen in the body.

When taken in large doses or for extended periods, these phytoestrogens can stimulate the growth of endometrial tissue and cause it to thicken, leading to an excessive buildup that eventually leads to uterine bleeding.

This side effect is often seen in women who are taking Pueraria mirifica supplements to alleviate menopausal symptoms.