10 Possible Side Effects Of Prunus Africana (African Plum)

Prunus africana, also known as African plum, has some side effects when used improperly, such as stomach cramps, diarrhea, and dizziness.

These side effects are often caused by taking excessive doses or combining the herb with other medications.

For example, stomach cramps and diarrhea can lead to dehydration, forcing individuals to miss work or school, while dizziness can cause accidents and injuries, compromising daily life and well-being.

This article explains in details the 10 most common side effects of Prunus africana if used imporperly.

1. Triggers respiratory issues

Prunus africana, also known as African plum, causes allergic reactions in some individuals.

This is due to the presence of allergenic compounds such as polyphenols and flavonoids in its extracts. These compounds can trigger an immune response, leading to symptoms like hives, itching, and swelling.

The allergenic potential is increased when Prunus africana is combined with other substances or taken in high doses, making it essential for users to be aware of the risk of allergic reactions.

2. Triggers respiratory issues

Prunus africana, also known as African plum, increases blood pressure due to its high concentration of epicatechin and other flavonoids.

These compounds can stimulate the sympathetic nervous system, leading to an increase in heart rate and blood pressure. Additionally, Prunus africana contains tyramine, a naturally occurring amino acid that can cause blood vessels to constrict, further contributing to elevated blood pressure levels.

As a result, individuals may experience increased blood pressure when using Prunus africana for therapeutic purposes.

3. Triggers respiratory issues

Prunus africana, also known as African Plum, lowers testosterone levels due to its ability to suppress the production of testosterone in the body.

This is because the herb contains compounds that can bind to androgen receptors, mimicking the effects of dihydrotestosterone (DHT), a potent form of testosterone.

As a result, natural testosterone production may decrease, leading to lower than normal testosterone levels.

4. Triggers respiratory issues

Prunus africana, also known as African plum, causes stomach upset in some individuals.

This is likely due to its tannin content, which can irritate the digestive tract and lead to nausea, vomiting, and abdominal pain. The high fiber content of Prunus africana may also contribute to stomach upset, potentially causing bloating and discomfort.

Additionally, the plant's ability to alter gut bacteria may further exacerbate gastrointestinal issues.

5. Triggers respiratory issues

Prunus africana, also known as African plum, triggers headaches due to its high concentration of flavonoids and phenolic acids.

These bioactive compounds can cause vasodilation and increased blood flow, leading to a constriction of the cerebral vessels and subsequent headache symptoms.

Additionally, the alkaloid content in Prunus africana may contribute to the development of headaches by stimulating the release of serotonin and other neurotransmitters that affect pain perception.

6. Triggers respiratory issues

Prunus africana, also known as African plum, raises liver enzymes due to its high concentration of iridoids and flavonoids.

These compounds can stimulate liver detoxification pathways, causing an increase in liver enzyme activity. This reaction is a normal response to the herb's phytochemicals and usually resolves once the body adjusts to their presence.

The liver's increased activity may lead to temporary changes in liver function tests, such as elevated alkaline phosphatase or transaminases.

7. Triggers respiratory issues

Prunus africana, also known as African plum, interacts with warfarin by increasing its effects.

This is due to the plant's ability to inhibit CYP2C9, an enzyme responsible for metabolizing warfarin in the liver.

As a result, the levels of warfarin in the blood may increase, leading to enhanced anticoagulant effects and potentially causing bleeding complications.

8. Triggers respiratory issues

Prunus africana, also known as African Plum, affects thyroid function by disrupting the body's ability to regulate thyroid hormones.

This is due to the presence of compounds like terpenoids and flavonoids, which can interfere with thyroid hormone production and metabolism.

As a result, some individuals may experience changes in their thyroid function, such as an underactive or overactive thyroid gland.

9. Triggers respiratory issues

Prunus africana, also known as African plum, decreases sperm count by inhibiting the activity of certain enzymes in the testes.

This herb contains a compound called quassinoid, which can affect the production and function of sperm, leading to reduced fertility in men who use it for extended periods.

Additionally, P. africana may interfere with hormone regulation, particularly testosterone levels, further contributing to decreased sperm count.

10. Triggers respiratory issues

Prunus africana, also known as African plum, causes dizziness in some individuals due to its ability to interact with certain medications and affect blood pressure.

The bark of the plant contains a compound called ursolic acid, which can cause a drop in blood pressure, leading to lightheadedness or dizziness. Additionally, Prunus africana may also stimulate the nervous system, causing a rapid heart rate, palpitations, and dizziness.

These effects are more likely to occur when taken in large doses or combined with other substances that affect blood pressure.