10 Possible Side Effects Of Prunella Vulgaris (Selfheal)

Prunella vulgaris has some side effects when used improperly, such as allergic reactions, digestive issues, and interact with medications.

These side effects can be caused by excessive consumption, individual sensitivities, or interactions with other substances.

For instance, allergic reactions can cause respiratory problems, digestive issues can lead to stomach pain and diarrhea, and interactions with medications can result in adverse effects on the cardiovascular system or exacerbate underlying health conditions, affecting one's overall well-being.

This article explains in details the 10 most common side effects of Prunella vulgaris if used imporperly.

1. Leads to seizures

Prunella vulgaris causes allergic reactions in some individuals due to its potential to stimulate an overactive immune response.

This may occur when the body perceives certain compounds within Prunella vulgaris as foreign or threatening, triggering an immune-mediated reaction characterized by symptoms such as hives, itching, and difficulty breathing.

The exact mechanisms underlying this hypersensitivity are not fully understood, but it is thought that the plant's bioactive compounds, including flavonoids and phenolic acids, play a role in eliciting these adverse responses.

2. Leads to seizures

Prunella vulgaris triggers skin rash due to its high concentration of allergenic compounds such as flavonoids and phenolic acids.

These substances can cause an immune response in some individuals, leading to the development of a skin rash characterized by redness, itching, and swelling.

Additionally, Prunella vulgaris may also contain latex-like proteins that can trigger allergic reactions, exacerbating the symptoms of the rash.

3. Leads to seizures

Prunella vulgaris induces vomiting due to its saponin content, which can irritate the stomach lining and cause nausea and vomiting.

The herb's bitter taste and astringent properties may also contribute to this side effect by irritating the digestive tract and altering gut motility.

In some individuals, the saponins may interact with other compounds in the body, leading to an upset stomach and subsequent vomiting.

4. Leads to seizures

Prunella vulgaris increases heart rate due to its ability to stimulate the nervous system and enhance circulation.

The herb's bioactive compounds, such as rosmarinic acid and flavonoids, can act as beta-adrenergic agonists, mimicking the effects of adrenaline on the heart.

This leads to an increase in heart rate and blood pressure, which may be beneficial for certain conditions but potentially problematic for individuals with pre-existing cardiovascular issues.

5. Leads to seizures

Prunella vulgaris lowers blood pressure by inhibiting the angiotensin-converting enzyme (ACE) activity, which is responsible for converting angiotensin I to angiotensin II, a potent vasoconstrictor.

This inhibition leads to a decrease in peripheral vascular resistance and systolic blood pressure, resulting in hypotension.

Additionally, Prunella vulgaris may also interact with the renin-angiotensin system, further contributing to its hypotensive effects.

6. Leads to seizures

Prunella vulgaris causes stomach upset due to its bitter and astringent properties.

The plant's high concentration of iridoid glycosides, such as aucubin and cinnamic acid, can irritate the mucous membranes in the digestive tract, leading to stomach cramps, bloating, and discomfort.

Additionally, the plant's tannins may also contribute to this side effect by reducing the secretion of digestive enzymes and altering gut motility, causing nausea and stomach pain.

7. Leads to seizures

Prunella vulgaris activates asthma attacks due to its potential allergenic properties.

The plant contains a number of bioactive compounds, including flavonoids and phenolic acids, which can trigger an allergic response in susceptible individuals.

In people with pre-existing asthma, these substances may cause an intense inflammatory reaction, leading to bronchospasm and airway constriction, further exacerbating symptoms of asthma attacks.

8. Leads to seizures

Prunella vulgaris weakens immune system by suppressing the activity of white blood cells, which play a crucial role in fighting off infections and diseases.

The herb's immunosuppressive properties can lead to decreased resistance to infections, making individuals more susceptible to illnesses such as the common cold, flu, and other viral infections.

This side effect may occur due to the presence of certain compounds like flavonoids, terpenes, and phenolic acids in Prunella vulgaris, which can inhibit the production of cytokines and other immune cells.

9. Leads to seizures

10. Leads to seizures

Prunella vulgaris disrupts menstrual cycle.

This side effect is attributed to its estrogen-like properties, which can alter the normal balance of hormones in the body. The herb's ability to stimulate the production of prolactin, a hormone that regulates milk production, may also contribute to this disruption. Additionally, Prunella's influence on the endometrium, the lining of the uterus, may affect menstruation by altering its thickness and shedding patterns.

As a result, individuals using Prunella vulgaris may experience irregular or absent menstrual periods.