13 Best Polygonum Multiflorum Benefits

Polygonum multiflorum, commonly known as the Chinese knotweed, is a versatile plant with numerous health benefits.
It is rich in antioxidants, which help combat oxidative stress and reduce the risk of chronic diseases such as heart disease and cancer.
The plant has been traditionally used to improve liver function, enhance immune response, and support digestive health, making it beneficial for overall wellness.
Incorporating Polygonum multiflorum into one's diet or routine can lead to increased energy levels, better skin health, and improved mental clarity, thus enhancing everyday life quality.
Below there's a list of the 13 best health benefits of polygonum multiflorum.
- 1. Heals liver damage
- 2. Reduces inflammation
- 3. Boosts immune system
- 4. Fights bacterial infections
- 5. Fights fungal infections
- 6. Improves digestion
- 7. Reduces anxiety
- 8. Fights viral infections
- 9. Fights cancer cells
- 10. Helps weight loss
- 11. Lowers cholesterol levels
- 12. Lowers blood pressure
- 13. Soothes skin issues
1. Heals liver damage
Liver damage refers to the impairment of liver function, often resulting from toxic exposure, chronic disease, or excessive alcohol consumption.
This condition can manifest as hepatic injury, liver dysfunction, or hepatic impairment, and it commonly affects individuals with long-term alcohol use, viral hepatitis, or those exposed to environmental toxins.
Polygonum multiflorum, also known as Fo-ti, has been traditionally used in herbal medicine to support liver health and aid in the repair of damaged liver tissue.
Its bioactive compounds may help reduce inflammation and oxidative stress, which are key factors in liver damage.
This plant is particularly beneficial for those suffering from chronic liver conditions or seeking to detoxify and restore liver function.

How this herb helps with heals liver damage?
Polygonum multiflorum heals liver damage because it contains bioactive constituents such as alkaloids and flavonoids, which exhibit potent antioxidant and anti-inflammatory properties.
These compounds help neutralize free radicals and reduce oxidative stress, which are key factors in liver injury. The alkaloids in Polygonum multiflorum have been shown to support liver cell regeneration and improve detoxification processes. Flavonoids contribute to the plant's hepatoprotective effects by enhancing the liver's ability to metabolize toxins.
Together, these bioactive components make Polygonum multiflorum a valuable natural remedy for liver health.
Scientific Research
According to "Mini reviews in medicinal chemistry", Polygonum multiflorum does have the potential to heal liver damage, specifically in the context of nonalcoholic fatty liver disease (NAFLD), as mentioned in the study.
2. Reduces inflammation
Inflammation is a defensive response of the body to injury or infection, characterized by redness, swelling, and pain.
Chronic inflammation, a prolonged and often subtle form of this reaction, can lead to tissue damage and contribute to various diseases.
It is commonly caused by persistent exposure to irritants, autoimmune responses, or metabolic stress.
Individuals with conditions like arthritis, diabetes, or obesity are more likely to experience chronic inflammation.
Polygonum multiflorum has been shown to reduce inflammation by modulating immune responses and inhibiting inflammatory pathways.

How this herb helps with reduces inflammation?
Polygonum multiflorum reduces inflammation because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds possess anti-inflammatory properties that inhibit the production of pro-inflammatory cytokines. Alkaloids like emodin have been shown to suppress inflammatory pathways in the body. Flavonoids contribute by scavenging free radicals and modulating immune responses.
Together, these compounds support the plant's traditional use in reducing inflammation and promoting overall health.
Scientific Research
According to "Oxidative medicine and cellular longevity", Polygonum multiflorum, as a source of the active component THSG, has been shown to reduce inflammation, among other beneficial biological effects, indicating its potential positive impact on inflammation.
3. Boosts immune system
Immune system deficiency refers to a weakened ability of the body to defend against pathogens and diseases.
This condition can result from various factors such as poor nutrition, chronic stress, or underlying illnesses.
It commonly affects individuals with weakened immune systems, including the elderly, children, and those with chronic conditions.
Polygonum multiflorum has been found to enhance immune function by stimulating the production of white blood cells.
Its bioactive compounds help regulate immune responses and reduce susceptibility to infections.

How this herb helps with boosts immune system?
Polygonum multiflorum boosts immune system because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds help enhance the body's defense mechanisms by stimulating the production of immune cells. Alkaloids like emodin and berberine have antimicrobial and anti-inflammatory properties. Flavonoids contribute to the plant's antioxidant capacity, which supports overall immune function.
Together, these compounds promote a stronger and more resilient immune response.
Scientific Research
According to the study, Polygonum multiflorum (specifically Polygonatum cyrtonema Hua) has been found to boost the immune system by enhancing the immune capacity of the body, regulating the metabolism of blood glucose and lipids, and increasing the expression of immune-related factors such as IL-2, IFN-γ, IgA, and IgM.
4. Fights bacterial infections
Bacterial Infections are harmful conditions caused by the growth of bacteria in the body, leading to inflammation and tissue damage.
Also known as bacterial illnesses or bacterial contagions, these infections can affect various parts of the body, including the respiratory, urinary, and skin systems.
They often result from weakened immune systems, poor hygiene, or exposure to contaminated environments.
People with chronic illnesses, the elderly, and young children are more susceptible to bacterial infections.
Polygonum multiflorum has been traditionally used to support the body's natural defenses against such infections.

How this herb helps with fights bacterial infections?
Polygonum multiflorum fights bacterial infections because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds exhibit antimicrobial properties that inhibit the growth of harmful bacteria. Alkaloids like emodin and berberine have been shown to disrupt bacterial cell walls and interfere with their metabolic processes. Flavonoids contribute by reducing inflammation and enhancing the immune response against pathogens.
Together, these natural compounds make Polygonum multiflorum a valuable herb in traditional and modern medicine for combating bacterial infections.
5. Fights fungal infections
Fungal Infections are a common health issue caused by the overgrowth of fungi on the skin, nails, or mucous membranes.
These infections can be triggered by damp environments, weakened immune systems, or poor hygiene.
They often affect individuals with diabetes, athletes, or those with frequent exposure to moisture.
Polygonum multiflorum, also known as He Shou Wu, has been traditionally used to combat fungal infections due to its antimicrobial properties.
Its active compounds may inhibit the growth of fungi, offering a natural remedy for conditions like athlete's foot or nail fungus.

How this herb helps with fights fungal infections?
Polygonum multiflorum fights fungal infections because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds exhibit antifungal properties by disrupting the fungal cell membrane and inhibiting the growth of pathogenic fungi. Alkaloids like emodin and berberine contribute to its antimicrobial effects. Flavonoids help reduce oxidative stress and enhance the immune response against fungal invaders.
Together, these constituents make Polygonum multiflorum a valuable natural remedy for combating fungal infections.
6. Improves digestion
Digestive discomfort.
Functional gastrointestinal disorders, such as irritable bowel syndrome or sluggish digestion, often manifest as bloating, constipation, or irregular bowel movements.
These issues can arise from imbalanced gut flora, poor dietary habits, or stress, and are commonly experienced by individuals with a sedentary lifestyle or those suffering from chronic stress.
Polygonum multiflorum supports digestion by promoting healthy gut motility and reducing inflammation in the digestive tract.
Its traditional use in herbal medicine highlights its potential to enhance digestive efficiency and alleviate common digestive ailments.

How this herb helps with improves digestion?
Polygonum multiflorum improves digestion because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds help stimulate digestive enzymes and enhance gastrointestinal motility. Alkaloids like emodin contribute to the plant’s ability to regulate bowel movements. Flavonoids support the health of the digestive tract by reducing inflammation.
Together, these constituents promote efficient nutrient absorption and overall digestive wellness.
7. Reduces anxiety
Anxiety is a mental health condition characterized by excessive worry, restlessness, and a heightened sense of unease.
It often manifests as persistent feelings of tension, fear, or apprehension that interfere with daily life.
Anxiety can be triggered by stress, trauma, genetic factors, or imbalances in brain chemistry.
It commonly affects individuals experiencing high-pressure lifestyles, those with a family history of mental health disorders, or people facing significant life changes.
Polygonum multiflorum, also known as He Shou Wu, has been studied for its potential to alleviate anxiety by modulating neurotransmitter activity and promoting emotional stability.

How this herb helps with reduces anxiety?
Polygonum multiflorum reduces anxiety because it contains bioactive constituents such as alkaloids and flavonoids, which have been shown to modulate neurotransmitter activity in the brain.
These compounds may enhance the activity of GABA, a neurotransmitter that promotes relaxation and reduces stress. Alkaloids like emodin and polydatin contribute to the plant's anxiolytic effects by influencing inflammatory pathways and oxidative stress. Flavonoids in Polygonum multiflorum also support neuroprotection and improve mood regulation.
Overall, the synergistic action of these compounds makes Polygonum multiflorum a valuable natural remedy for reducing anxiety.
8. Fights viral infections
Viral Infections.
Viral infections are contagious illnesses caused by the rapid replication of viruses within the body, often leading to symptoms like fever, cough, and fatigue.
These infections can affect various organs and systems, depending on the type of virus involved.
They are commonly experienced by individuals with weakened immune systems, such as the elderly, young children, and those with chronic illnesses.
The polygonum multiflorum plant is believed to support the immune system, helping to combat viral infections by enhancing the body's natural defenses.

How this herb helps with fights viral infections?
Polygonum multiflorum fights viral infections because it contains bioactive constituents such as alkaloids and flavonoids, which exhibit antiviral properties.
These compounds interfere with viral replication by inhibiting the entry of viruses into host cells. Alkaloids like berberine and emodin have been shown to reduce viral load and enhance immune response. Flavonoids contribute to the plant's ability to modulate inflammatory responses and support antiviral defense mechanisms.
Overall, these natural compounds make Polygonum multiflorum a valuable herbal remedy in combating various viral infections.
9. Fights cancer cells
Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells.
This condition, also known as malignancy or neoplasia, occurs when genetic mutations disrupt normal cell regulation, leading to tumor formation.
It can affect various organs and tissues, and is commonly experienced by individuals across all age groups, though it is more prevalent in older adults.
Polygonum multiflorum, also known as He Shou Wu, has been studied for its potential to combat cancer cells by inducing apoptosis and inhibiting tumor growth.
Its bioactive compounds may help reduce the proliferation of malignant cells and enhance the body's immune response against cancer.

How this herb helps with fights cancer cells?
Polygonum multiflorum fights cancer cells because it contains bioactive constituents such as alkaloids and flavonoids, which exhibit potent anti-cancer properties.
These compounds inhibit the proliferation of cancer cells by inducing apoptosis and suppressing angiogenesis. Alkaloids like emodin have been shown to disrupt the cell cycle and trigger programmed cell death in malignant cells. Flavonoids contribute to the plant's antioxidant and anti-inflammatory effects, which support its cancer-fighting capabilities.
Overall, the synergistic action of these bioactive compounds makes Polygonum multiflorum a promising natural agent in cancer prevention and treatment.
10. Helps weight loss
Obesity is a medical condition characterized by excessive body fat that can lead to serious health complications.
Another term for this condition is overweight, which often results from an imbalance between calorie intake and expenditure.
Obesity is commonly caused by poor dietary habits, lack of physical activity, and genetic predispositions.
It is prevalent among adults and adolescents, particularly in urban areas with sedentary lifestyles.
Polygonum multiflorum, also known as Ho Shou Wu, has been studied for its potential to support weight loss by improving metabolic function and reducing fat accumulation.

How this herb helps with helps weight loss?
Polygonum multiflorum helps weight loss because it contains bioactive constituents such as alkaloids and flavonoids, which have been shown to regulate metabolism and enhance fat oxidation.
These compounds may also suppress appetite and reduce the absorption of dietary fats in the gastrointestinal tract. Alkaloids like emodin and berberine contribute to its thermogenic effects, promoting calorie expenditure. Flavonoids in the plant exhibit antioxidant and anti-inflammatory properties that support metabolic health.
Overall, the synergistic action of these bioactive compounds makes Polygonum multiflorum a promising natural aid for weight management.
Scientific Research
According to "Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie", Polygonum multiflorum (PME) was found to help with weight loss by suppressing the differentiation of pre-adipocytes into adipocytes and reducing visceral fat mass, size, and body weight in high-fat diet-induced obese mice.
11. Lowers cholesterol levels
Hypercholesterolemia, a condition marked by elevated levels of cholesterol in the bloodstream, poses significant risks to cardiovascular health.
This metabolic disorder arises from an imbalance between the body's production and elimination of cholesterol, often exacerbated by poor dietary habits, sedentary lifestyles, and genetic predispositions.
It predominantly affects middle-aged adults and individuals with a family history of heart disease.
Polygonum multiflorum, also known as Fo-ti, has been studied for its potential to reduce cholesterol levels by enhancing liver function and promoting the excretion of lipids.
Incorporating this plant into a balanced diet may support cholesterol management, though it should complement, not replace, conventional medical advice.

How this herb helps with lowers cholesterol levels?
Polygonum multiflorum lowers cholesterol levels because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds help reduce low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol. Alkaloids in the plant may inhibit the synthesis of cholesterol in the liver. Flavonoids act as antioxidants, preventing oxidative stress that contributes to cholesterol buildup.
Together, these components support cardiovascular health by improving lipid profiles.
Scientific Research
According to "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", Polygonum multiflorum reduces serum cholesterol levels, specifically lowering LDL-C levels.
12. Lowers blood pressure
Hypertension, also known as high blood pressure, is a chronic condition characterized by elevated pressure in the arteries.
This condition can lead to serious health complications if left untreated.
It is often caused by a combination of genetic, lifestyle, and environmental factors.
Individuals with a family history of hypertension, those who lead sedentary lifestyles, and people with poor dietary habits are more likely to experience it.
Polygonum multiflorum has been studied for its potential to lower blood pressure by improving vascular function and reducing oxidative stress.

How this herb helps with lowers blood pressure?
Polygonum multiflorum lowers blood pressure because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds help relax blood vessels and improve circulation. Alkaloids like emodin have been shown to reduce vascular resistance. Flavonoids contribute to the plant's antioxidant and anti-inflammatory properties.
Together, these components support cardiovascular health and aid in maintaining healthy blood pressure levels.
13. Soothes skin issues
Skin irritation.
Skin irritation refers to a range of inflammatory conditions that cause redness, itching, and discomfort on the skin.
It can be triggered by allergens, irritants, or environmental factors, and is commonly experienced by individuals with sensitive skin, eczema, or those exposed to harsh chemicals.
Polygonum multiflorum, also known as Fo-Ti, is believed to possess soothing properties that may help alleviate these symptoms.
Its anti-inflammatory and antioxidant compounds are thought to reduce redness and promote skin healing, making it a potential natural remedy for those suffering from persistent skin discomfort.

How this herb helps with soothes skin issues?
Polygonum multiflorum soothes skin issues because it contains bioactive constituents such as alkaloids and flavonoids.
These compounds possess anti-inflammatory and antioxidant properties that help reduce redness and irritation. The alkaloids in the plant may inhibit the production of inflammatory cytokines. Flavonoids contribute to the plant's ability to protect skin cells from oxidative stress.
Together, these components support the healing and regeneration of damaged skin tissue.