Polygonum Multiflorum Uses, Benefits, And Remedies

Polygonum multiflorum, commonly known as the Chinese knotweed, is a perennial herb native to East Asia, widely used in traditional Chinese medicine.
It is valued for its potential to support liver health, enhance immunity, and promote longevity.
The herb contains bioactive constituents such as anthraquinones, polysaccharides, and stilbenes, which contribute to its therapeutic properties.
It can be prepared as an infusion, decoction, or tincture, and is often used in herbal formulations for its purported health benefits.
This page analize the most important medicinal aspects of Polygonum multiflorum.
- Health Benefits
- Bioactive Constituents
- Medicinal Parts
- Herbal Preparations
- Side Effects of polygonum multiflorum
Health Benefits
Polygonum multiflorum heals liver damage by promoting detoxification and regeneration of liver cells, making it a valuable herbal remedy for those suffering from liver disorders.
This herb also reduces inflammation through its rich content of antioxidants and anti-inflammatory compounds, which help alleviate symptoms associated with chronic inflammatory conditions. Additionally, Polygonum multiflorum boosts the immune system by enhancing the production of immune cells and modulating immune responses, thereby improving the body's ability to fight off infections. Its ability to fight bacterial infections is attributed to its antimicrobial properties, which inhibit the growth of harmful bacteria and support overall immune health.
Overall, Polygonum multiflorum offers a range of health benefits that make it a promising natural supplement for improving liver function, reducing inflammation, and strengthening the immune system.
The 13 best health benefits of Polygonum multiflorum are shown in the image below.

The list below give a brief description of the 13 best health benefits of Polygonum multiflorum.
- Heals Liver Damage: Polygonum multiflorum contains antioxidants and anti-inflammatory compounds that support liver function and aid in the repair of damaged liver tissue.
- Reduces Inflammation: The herb contains polyphenols and other bioactive compounds that help reduce inflammation in the body, alleviating symptoms of inflammatory conditions.
- Boosts Immune System: Polygonum multiflorum enhances immune function by stimulating the production of immune cells and improving the body's defense against pathogens.
- Fights Bacterial Infections: The herb exhibits antimicrobial properties that help combat bacterial infections by inhibiting the growth of harmful bacteria.
- Fights Fungal Infections: Polygonum multiflorum contains compounds that inhibit the growth of fungi, making it effective against fungal infections such as candidiasis.
- Improves Digestion: It aids in digestion by promoting the secretion of digestive enzymes and reducing gastrointestinal discomfort.
- Reduces Anxiety: The herb has calming effects on the nervous system, helping to reduce stress and anxiety levels.
- Fights Viral Infections: Polygonum multiflorum possesses antiviral properties that can help the body combat viral infections more effectively.
- Fights Cancer Cells: Studies suggest that the herb contains compounds that may inhibit the growth of cancer cells and induce apoptosis in malignant cells.
- Helps Weight Loss: It may support weight loss by enhancing metabolism and reducing appetite, aiding in calorie control and fat loss.
- Lowers Cholesterol Levels: Polygonum multiflorum helps reduce LDL cholesterol levels, promoting heart health and reducing the risk of cardiovascular diseases.
- Lowers Blood Pressure: The herb has been shown to help regulate blood pressure by improving vascular function and reducing oxidative stress.
- Soothes Skin Issues: It can be used topically to treat skin conditions such as acne, eczema, and wounds due to its anti-inflammatory and antimicrobial properties.
Bioactive Constituents
Polygonum multiflorum triterpenoids have been identified as key medicinal constituents of the herb, contributing to its traditional use in Chinese medicine for their anti-inflammatory and antioxidant properties.
These compounds, such as polyhydroxy triterpenoids, are known to inhibit inflammatory pathways and reduce oxidative stress, making them beneficial for conditions like arthritis and skin disorders. In addition to triterpenoids, saponins present in Polygonum multiflorum also play a significant role, exhibiting antimicrobial and immunomodulatory effects that support the herb's use in treating infections and enhancing immune function.
Polysaccharides from the herb are valued for their ability to boost immune response and exhibit antitumor activities, further enhancing its therapeutic potential. Lastly, flavonoids, another group of bioactive compounds found in Polygonum multiflorum, contribute to its antioxidant and neuroprotective properties, supporting its traditional applications in promoting longevity and cognitive health.
Together, these constituents make Polygonum multiflorum a versatile herb with a wide range of medicinal benefits.
The 9 best bioactive constituents of Polygonum multiflorum are shown in the image below.

The list below give a brief description of the 13 best bioactive constituents of Polygonum multiflorum.
- Triterpenoids: Triterpenoids are a class of organic compounds found in Polygonum multiflorum, known for their anti-inflammatory and antioxidant properties, contributing to the herb's medicinal effects.
- Saponins: Saponins are natural compounds that exhibit antimicrobial, anti-inflammatory, and immune-modulating properties, commonly found in Polygonum multiflorum.
- Polysaccharides: Polysaccharides are complex carbohydrates that have immunostimulatory and antioxidant effects, enhancing the body's immune response and promoting health.
- Flavonoids: Flavonoids are plant-derived compounds with antioxidant, anti-inflammatory, and neuroprotective properties, contributing to the therapeutic value of Polygonum multiflorum.
- Glycosides: Glycosides are compounds composed of a sugar molecule attached to a non-sugar component, often exhibiting cardiovascular and anti-inflammatory benefits in Polygonum multiflorum.
- Phytosterols: Phytosterols are plant sterols that may help lower cholesterol levels and have anti-inflammatory and immune-modulating effects.
- Phenolic Acids: Phenolic acids are a group of antioxidants that help neutralize free radicals, reduce inflammation, and support overall health in Polygonum multiflorum.
- Sterols: Sterols are organic compounds that may help regulate cholesterol levels and have anti-inflammatory and antioxidant properties.
- Amino Acids: Amino acids are the building blocks of proteins and are essential for various physiological functions, contributing to the nutritional value of Polygonum multiflorum.
Medicinal Parts
Polygonum multiflorum root, also known as He Shou Wu, is a key medicinal part of the Polygonum multiflorum herb, widely used in traditional Chinese medicine.
This root is renowned for its rich content of anthraquinone derivatives, which contribute to its various therapeutic properties. It is commonly employed to nourish the liver and kidneys, improve circulation, and promote hair growth, making it a popular remedy for aging-related conditions. In addition to its traditional uses, modern research suggests that the root may have antioxidant, anti-inflammatory, and neuroprotective effects.
The root is typically processed through methods such as wine-steaming or vinegar-steaming to enhance its medicinal properties and reduce potential toxicity, ensuring its safe and effective use in herbal formulations.
The 1 best medicinal parts of Polygonum multiflorum are shown in the image below.

The list below give a brief description of the 1 best medicinal parts of Polygonum multiflorum.
Herbal Preparations
Polygonum multiflorum decoctions are one of the most traditional and widely used preparations of this herb, often made by simmering the dried root in water for an extended period to extract its active compounds.
These decoctions are commonly consumed as a tonic to support liver function, detoxification, and overall vitality, and are a staple in traditional Chinese medicine. In addition to decoctions, Polygonum multiflorum is also used to make teas, which are typically brewed from the dried root and consumed for their mild, earthy flavor and purported health benefits. Tinctures and capsules offer more concentrated forms of the herb, allowing for easier dosing and portability, while creams and ointments are applied topically to treat skin conditions and promote wound healing.
Other preparations such as oils, syrups, and poultices are also utilized, each tailored to specific therapeutic applications, highlighting the versatility of Polygonum multiflorum in herbal medicine.
The 12 best herbal preparations of Polygonum multiflorum are shown in the image below.

The list below give a brief description of the 12 best herbal preparations of Polygonum multiflorum.
- Decoctions: Polygonum multiflorum decoctions are used to nourish the liver and kidneys, improve circulation, and support overall vitality.
- Teas: Polygonum multiflorum teas are traditionally used to enhance vitality, support digestive health, and promote longevity.
- Tinctures: Polygonum multiflorum tinctures are used to strengthen the body, support liver function, and enhance immunity.
- Creams: Polygonum multiflorum creams are applied topically to treat skin conditions, reduce inflammation, and promote skin health.
- Capsules: Polygonum multiflorum capsules are used to support liver and kidney health, improve circulation, and enhance overall vitality.
- Oinments: Polygonum multiflorum ointments are used externally to relieve skin irritations, reduce inflammation, and promote healing.
- Oils: Polygonum multiflorum oils are used to nourish the skin, improve circulation, and support overall health.
- Syrups: Polygonum multiflorum syrups are used to support respiratory health, enhance vitality, and promote longevity.
- Mucillages: Polygonum multiflorum mucillages are used to soothe the digestive tract, reduce inflammation, and support gut health.
- Lozenges: Polygonum multiflorum lozenges are used to relieve sore throats, support respiratory health, and enhance vitality.
- Liniments: Polygonum multiflorum liniments are used to reduce muscle pain, improve circulation, and alleviate joint discomfort.
- Poultices: Polygonum multiflorum poultices are applied externally to treat wounds, reduce inflammation, and promote healing.
Side Effects of polygonum multiflorum
Polygonum multiflorum may cause diarrhea due to its high content of anthraquinone compounds, which can stimulate intestinal motility and lead to loose stools.
The herb can cause stomach upset because it contains irritant compounds that may inflame the gastrointestinal tract, leading to discomfort and nausea. Polygonum multiflorum triggers skin rash as it contains allergenic substances that can provoke an immune response, resulting in itching and redness.
The herb results in headache possibly due to its effect on blood circulation and the potential for dehydration, which can contribute to migraines or tension headaches.
The 7 most common side effects of Polygonum multiflorum are shown in the image below.

The list below give a brief description of the 7 most common side effects of Polygonum multiflorum.
- May Cause Diarrhea: Polygonum multiflorum may lead to diarrhea due to its laxative properties or irritation of the digestive tract.
- Causes Stomach Upset: Consuming Polygonum multiflorum can cause stomach discomfort, nausea, or bloating in some individuals.
- Triggers Skin Rash: Some people may develop skin rashes or itching as an allergic response to Polygonum multiflorum.
- Results In Headache: Polygonum multiflorum may cause headaches, possibly due to its impact on the body's internal balance or blood pressure.
- May Cause Dry Mouth: The herb may lead to dry mouth due to its potential dehydrating effects or influence on saliva production.
- Triggers Allergic Reaction: Polygonum multiflorum can trigger allergic reactions in sensitive individuals, including hives or swelling.
- Causes Gastrointestinal Issues: The herb may cause various gastrointestinal issues such as indigestion or stomach pain in some users.