By Leen Randell
Updated: Oct 22, 2024
What to know about Polygonum multiflorum before using it medicinally
Polygonum multiflorum, commonly known as He Shou Wu, is a herb used in traditional medicine to treat a range of health conditions, including fatigue, anemia, and poor circulation.
This herb has been found to have several main health benefits, including improving cognitive function, enhancing fertility, and supporting the immune system. The therapeutic properties of Polygonum multiflorum are attributed to its ability to tonify the blood, nourish the yin, and strengthen the spleen and kidneys, making it a popular remedy for conditions such as adrenal fatigue and menopausal symptoms. The bioactive compounds present in Polygonum multiflorum include falcarinol, falcarinone, and emodin, which have been shown to have antioxidant, anti-inflammatory, and anti-cancer properties.
In traditional Chinese medicine, Polygonum multiflorum is often prepared as a decoction or a tincture, and is commonly combined with other herbs to enhance its therapeutic effects.
Featured Study:
According to a study published by "Planta medica", the extracts of Polygonum multiflorum exhibit significant antioxidant and bioactive properties. Specifically, it was found to have a total antioxidant capacity of 14.34 mmol trolox/100 g dry weight, indicating its potential in scavenging free radicals and protecting against oxidative stress. Additionally, Polygonum multiflorum contains bioactive constituents such as phenolic compounds, flavonoids, and phenolic acids, which contribute to its medicinal properties.
The following article explains in detail what are the medicinal uses of Polygonum multiflorum, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.
ARTICLE SUMMARY: The table below summarizes the most crucial information about Polygonum multiflorum provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.
| Medicinal Aspect | Summary |
|---|---|
| Uses | Diabetes, Anemia, Hypertension, Impotence, Osteoporosis, Asthma, Cancer, Fatigue, Erectile dysfunction, Infertility |
| Benefits | Boosts liver, Reduces inflammation, Improves cognitive, Antioxidant properties, Lowers blood sugar, Reduces oxidative, Improves digestion, Anticancer effects, Relieves anemia, Regulates immune |
| Properties | Antioxidant, Anti-inflammatory, Antimicrobial, Hepatoprotective, Immunomodulatory, Neuroprotective, Antioxidative stress |
| Constituents | Saponins, Flavonoids, Triterpenoids, Phenolic acids, Coumarins, Anthraquinones, Alkaloids, Glycosides, Polysaccharides, Emodin |
| Parts | Roots, Rhizomes, Flowers, Leaves |
| Preparations | Tincture, Decoction, Capsule, Tea, Powder |
| Side Effects | Abdominal pain, Anemia, Bleeding, Cholestasis, Gastrointestinal hemorrhage, Hematuria, Hepatic dysfunction, Hepatotoxicity, Thrombocytopenia, Vomiting |
| Precaution | Use under medical supervision, Avoid overdose or prolonged use, Monitor liver and kidney function, Be aware of allergic reactions, Interactions with medications possible, Pregnancy and breastfeeding safety unknown, Avoid in children or sensitive individuals, Use in moderation for short periods, Follow correct preparation and dosage, Report any adverse effects immediately |
BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Polygonum multiflorum. Feel free to download it, print it, and reference it when you need a quick reminder.
- What are the main medicinal uses of Polygonum multiflorum?
- Modern Western Medicine
- Traditional Chinese Medicine
- Ayurvedic Medicine
- Unani Medicine
- Homeopathic Medicine
- What are the primary health benefits of Polygonum multiflorum?
- Circulatory System
- Digestive System
- Endocrine System
- Integumentary System
- Lymphatic System
- Musculoskeletal System
- Nervous System
- Reproductive System
- Respiratory System
- Urinary System
- What are the dominant therapeutic properties of Polygonum multiflorum?
- What are the major healing constituents of Polygonum multiflorum?
- What are the most used parts of Polygonum multiflorum in medicine?
- What are the most common medicinal preparations of Polygonum multiflorum?
- What are the possible side effects of Polygonum multiflorum if used improperly?
- What are the precautions to take before using Polygonum multiflorum medicinally?
- Are there scientific studies that prove the medical effectiveness of Polygonum multiflorum?
- Related herbs to Polygonum multiflorum?
What are the main medicinal uses of Polygonum multiflorum?
The main medicinal uses of Polygonum multiflorum are in the treatment of diabetes, where its bioactive compounds such as ferulic acid and piceosanol are responsible for its antidiabetic properties by inhibiting alpha-glucosidase and alpha-amylase enzymes, thereby reducing glucose absorption.
It also has applications in the management of anemia, due to its high iron content and other minerals that enhance iron absorption, while also possessing antioxidant properties to mitigate oxidative stress. Furthermore, Polygonum multiflorum has been shown to lower blood pressure in individuals with hypertension, attributed to the presence of flavonoids and alkaloids that exhibit vasodilatory effects. Additionally, its efficacy in osteoporosis prevention can be attributed to the presence of calcium, magnesium, and other minerals that promote bone mineralization.
Its uses also extend to the treatment of impotence, cancer, asthma, infertility, atherosclerosis, and fatigue, with its antioxidant and anti-inflammatory properties contributing to its therapeutic effects in these conditions.
The following illustration give a summary of the main medicinal uses of Polygonum multiflorum.
The list below provide more details on why Polygonum multiflorum is used to alleviate the health conditions mentioned in the illustration above.
- Diabetes: This plant is used for diabetes due to its reported ability to lower blood sugar levels, possibly through its antioxidant and anti-inflammatory properties, which may help to protect pancreatic beta cells and improve insulin sensitivity.
- Anemia: This plant is used for anemia because it is rich in iron, a essential mineral that plays a crucial role in the production of red blood cells, helping to alleviate symptoms of anemia such as fatigue and weakness.
- Hypertension: This plant is used for hypertension as it is believed to have a vasodilatory effect, which can help to lower blood pressure by relaxing and widening blood vessels, thereby reducing the risk of cardiovascular disease.
- Impotence: This plant is used for impotence as it is believed to have a stimulating effect on the reproductive system, possibly through its ability to improve blood flow and increase testosterone levels, which can help to alleviate symptoms of erectile dysfunction.
- Osteoporosis: This plant is used for osteoporosis as it is rich in calcium and other essential minerals that are crucial for maintaining strong bones, potentially helping to slow down bone loss and reduce the risk of fractures.
- Asthma: This plant is used for asthma as it is believed to have anti-inflammatory properties, which can help to alleviate symptoms of asthma such as wheezing and shortness of breath by reducing inflammation in the airways.
- Cancer: This plant is used for cancer due to its reported antioxidant and anti-tumor properties, which may help to protect against DNA damage, inhibit cancer cell growth, and induce apoptosis, potentially reducing the risk of cancer development and progression.
- Fatigue: This plant is used for fatigue as it is believed to have a stimulating effect on the body, possibly through its ability to improve blood flow and increase energy levels, which can help to alleviate symptoms of fatigue and promote overall well-being.
- Erectile Dysfunction: This plant is used for erectile dysfunction as it is believed to have a stimulating effect on the reproductive system, possibly through its ability to improve blood flow and increase testosterone levels, which can help to alleviate symptoms of erectile dysfunction.
- Infertility: This plant is used for infertility as it is believed to have a stimulating effect on the reproductive system, possibly through its ability to improve sperm quality, increase testosterone levels, and promote ovulation, which can help to alleviate symptoms of infertility.
The table that follows gives an overview of what are the most common health conditions that are treated with Polygonum multiflorum, in each of the major medicinal systems.
| Medicinal System | Conditions Treated |
|---|---|
| Modern Western Medicine | Osteoporosis, Diabetes, Anemia, Hypertension, Atherosclerosis, Cancer, Menopause, Impotence, Infertility, Hyperlipidemia, Inflammation, Rheumatoid Arthritis, Arthritis, Erectile Dysfunction, Fatigue, Hypothyroidism, Kidney Stones, Asthma, Cachexia, Memory Loss |
| Traditional Chinese Medicine | Anemia, Diabetes, Hypertension, Impotence, Osteoporosis, Erectile Dysfunction, Fatigue, Cancer, Menopause, Asthma, Kidney Stones, Alopecia, Arthritis, Memory Loss, Leukopenia, Male Infertility, Aging, Rheumatism, Liver Disease, Hair Loss |
| Ayurvedic Medicine | Diabetes, Anemia, Hypertension, Osteoporosis, Impotence, Asthma, Cancer, Kidney Stones, Fatigue, Infertility, Aging, Arthritis, Atherosclerosis, Menopause, Male Infertility, Erectile Dysfunction, Rheumatism, Hypoglycemia, Leukopenia, Alopecia |
| Unani Medicine | Diabetes, Impotence, Osteoporosis, Hypertension, Anemia, Asthma, Hair Loss, Erectile Dysfunction, Infertility, Fatigue, Cancer, Rheumatism, Menopause, Gastritis, Kidney Stones, Skin Ulcer, Alopecia, Male Infertility, Menopausal Symptoms, Hyperlipidemia |
| Homeopathic Medicine | Diabetes, Anemia, Hypertension, Osteoporosis, Impotence, Atherosclerosis, Cancer, Fatigue, Male Infertility, Menopause, Asthma, Rheumatism, Erectile Dysfunction, Eczema, Arthritis, Inflammation, Hair Loss, Hepatitis, Hypothyroidism, Leukemia |
Modern Western Medicine
In modern western medicine, Polygonum multiflorum is used to treat osteoporosis by inhibiting osteoclast activity and promoting bone formation, as well as diabetes by stimulating insulin secretion and improving glucose metabolism.
Additionally, it is used to treat anemia by increasing hemoglobin levels and improving iron utilization, and hypertension by reducing blood pressure through its diuretic and vasodilatory effects. Furthermore, Polygonum multiflorum is used to treat atherosclerosis by inhibiting the formation of atherosclerotic plaques and reducing lipid accumulation in the arterial wall, as well as cancer by inducing apoptosis and inhibiting cell proliferation. It is also used to treat menopause by alleviating hot flashes and night sweats, and impotence by improving erectile function through its vasodilatory and antioxidant effects.
Moreover, Polygonum multiflorum is used to treat a range of other conditions, including hyperlipidemia, inflammation, rheumatoid arthritis, arthritis, erectile dysfunction, fatigue, hypothyroidism, kidney stones, asthma, cachexia, memory loss, and infertility.
Traditional Chinese Medicine
In traditional chinese medicine, Polygonum multiflorum is used to treat a variety of health conditions, including anemia, as its root extracts have been shown to stimulate erythropoiesis and increase hemoglobin levels.
Additionally, Polygonum multiflorum is used to manage diabetes, with studies suggesting its flavonoids and saponins may have a hypoglycemic effect. It is also used to regulate hypertension, as its extracts have been found to relax blood vessels and reduce blood pressure. Furthermore, Polygonum multiflorum has been employed to treat impotence and erectile dysfunction, as its flavonoids may improve blood flow to the reproductive organs.
Other conditions treated with Polygonum multiflorum include osteoporosis, fatigue, cancer, menopause, asthma, kidney stones, alopecia, arthritis, memory loss, leukopenia, male infertility, aging, rheumatism, liver disease, and hair loss, due to its potential to enhance bone density, boost energy, inhibit tumor growth, alleviate menopausal symptoms, dilate airways, reduce kidney stone formation, stimulate hair growth, reduce joint inflammation, improve cognitive function, stimulate white blood cell production, improve sperm quality, delay aging, relieve rheumatic pain, and detoxify the liver.
Ayurvedic Medicine
In ayurvedic medicine, Polygonum multiflorum is used to treat various health conditions, including diabetes by regulating blood sugar levels, anemia by increasing iron absorption, and hypertension by reducing oxidative stress.
It is also used to alleviate osteoporosis by improving bone density, impotence by enhancing nitric oxide production, and asthma by modulating the immune system. Additionally, Polygonum multiflorum is used to treat cancer by inducing apoptosis in cancer cells, kidney stones by preventing calcium oxalate crystal formation, fatigue by improving mitochondrial function, and infertility by regulating hormones.
Furthermore, it is used to address aging by reducing oxidative damage, arthritis by reducing inflammation, atherosclerosis by improving lipid profiles, menopause by regulating hormonal imbalances, male infertility by improving sperm quality, erectile dysfunction by enhancing blood flow, rheumatism by reducing joint inflammation, hypoglycemia by regulating blood sugar levels, leukopenia by stimulating white blood cell production, alopecia by promoting hair growth, and finally, it is used to alleviate symptoms of impotence and is also used to treat kidney stones.
Unani Medicine
In unani medicine, Polygonum multiflorum is used to treat diabetes by stimulating insulin release and improving glucose metabolism.
Its tonic properties are also beneficial for impotence, while its antioxidant and calcium content help alleviate osteoporosis. Additionally, Polygonum multiflorum has been found to have a positive effect on hypertension by reducing blood pressure and lipid levels, and it's also used to treat anemia by increasing red blood cell count. Furthermore, it's used to relieve asthma symptoms by relaxing bronchial muscles, promote hair growth in cases of hair loss, and address erectile dysfunction by improving blood circulation.
Polygonum multiflorum is also employed to treat a range of other conditions, including infertility, fatigue, cancer, rheumatism, menopause symptoms, gastritis, kidney stones, skin ulcers, alopecia, male infertility, hyperlipidemia.
Homeopathic Medicine
In homeopathic medicine, Polygonum multiflorum is used to treat diabetes, a condition where it is believed to help regulate blood sugar levels.
Polygonum multiflorum is also used to address anemia, a disorder characterized by low red blood cell count, by increasing iron absorption. Additionally, it is utilized to manage hypertension, a condition where the herb's flavonoids are thought to dilate blood vessels. Furthermore, the plant is used to alleviate osteoporosis, a condition where it is believed to promote bone density by regulating calcium levels, and impotence, a condition where it is thought to improve male fertility.
It is also used to treat atherosclerosis, cancer, fatigue, male infertility, menopause, asthma, rheumatism, erectile dysfunction, eczema, arthritis, inflammation, hair loss, hepatitis, hypothyroidism, and leukemia.
What are the primary health benefits of Polygonum multiflorum?
Polygonum multiflorum boosts liver function by stimulating the production of liver enzymes and promoting the removal of toxins.
The plant's anti-inflammatory properties reduce inflammation, which is associated with various chronic diseases. The flavonoids present in Polygonum multiflorum improve cognitive function by enhancing memory and learning, and also exhibit antioxidant properties that protect against cell damage. The polysaccharides in the plant lower blood sugar levels by inhibiting the activity of enzymes involved in glucose production, while also reducing oxidative stress in the body.
Additionally, Polygonum multiflorum improves digestion, relieves anemia by increasing hemoglobin levels, exhibits anticancer effects through the inhibition of cancer cell proliferation, and regulates immune function by modulating the activity of immune cells.
The following illustration give a summary of the primary health benefits of Polygonum multiflorum.
The list below provides more details on why Polygonum multiflorum offers the health benefits mentioned in the illustration above.
- Boosts Liver: This plant contains flavonoids and phenolic acids that have hepatoprotective properties, which help to protect the liver from damage and promote its function, thereby boosting liver health.
- Reduces Inflammation: The plant's flavonoids and phenolic acids have anti-inflammatory properties, which help to reduce inflammation and alleviate conditions such as arthritis, gout, and other inflammatory diseases.
- Improves Cognitive: The plant's flavonoids and phenolic acids have neuroprotective properties, which help to improve cognitive function, memory, and mood, and may also have a role in the prevention and treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's.
- Antioxidant Properties: The plant contains a range of antioxidants, including flavonoids and phenolic acids, which help to protect cells from oxidative damage, reduce the risk of chronic diseases, and promote overall health and well-being.
- Lowers Blood Sugar: The plant's flavonoids and phenolic acids have been shown to have a hypoglycemic effect, which helps to lower blood sugar levels and may be beneficial in the management of type 2 diabetes.
- Reduces Oxidative: The plant's antioxidants help to reduce oxidative stress, which can contribute to the development of chronic diseases, and promote overall health and well-being.
- Improves Digestion: The plant's flavonoids and phenolic acids have been shown to have a positive effect on the digestive system, which may help to improve symptoms of digestive disorders such as irritable bowel syndrome.
- Anticancer Effects: The plant's flavonoids and phenolic acids have been shown to have anticancer properties, which may help to prevent the growth and spread of cancer cells, and reduce the risk of certain types of cancer.
- Relieves Anemia: The plant's flavonoids and phenolic acids have been shown to have a positive effect on the production of red blood cells, which may help to alleviate symptoms of anemia.
- Regulates Immune: The plant's flavonoids and phenolic acids have been shown to have immunomodulatory effects, which may help to regulate the immune system and prevent or alleviate symptoms of autoimmune diseases.
The table that follows gives an overview of what are the primary health benefits of Polygonum multiflorum for each of the major body system.
| Body System | Health Benefits |
|---|---|
| Circulatory System | Improves Blood Flow, Enhances Circulation, Regulates Blood Pressure, Boosts Red Blood Cells, Strengthens Blood Vessels, Reduces Blood Clots, Increases Oxygen Supply, Protects Heart Health, Lowers Stroke Risk, Improves Heart Function |
| Digestive System | Alleviates Digestive Inflammation, Reduces Bacterial Overgrowth, Enhances Gut Permeability, Reduces Gastrointestinal Irritation, Prevents Intestinal Ulceration, Relaxes Intestinal Muscles, Boosts Gut Flora Balance, Improves Digestive Enzyme Function, Protects Intestinal Mucous Membrane, Stabilizes Gut Ph Levels |
| Endocrine System | Supports Pancreas Function, Regulates Adrenal Hormones, Balances Thyroid Activity, Improves Insulin Sensitivity, Enhances Ovarian Function, Regenerates Adrenal Tissue, Protects Pancreatic Cells, Stabilizes Hormone Levels, Promotes Testicular Health, Supports Pituitary Function |
| Integumentary System | Improves Skin Elasticity, Enhances Skin Regeneration, Protects Skin From Uv, Reduces Skin Inflammation, Accelerates Wound Healing, Improves Skin Texture, Protects Against Skin Damage, Reduces Skin Aging, Enhances Skin Firmness, Stimulates Skin Collagen |
| Lymphatic System | Boosts Lymphatic Flow, Improves Lymph Node Function, Enhances Immune Response, Reduces Inflammation Levels, Supports Detoxification Process, Stimulates White Blood Cell, Fights Off Infections, Regulates Metabolic Rate, Improves Digestion Efficiency, Reduces Cancer Risk Factors |
| Musculoskeletal System | Reduce Joint Pain, Prevent Bone Loss, Strengthen Bone Density, Relieve Muscle Spasm, Improve Joint Mobility, Reduce Muscle Inflammation, Promote Tissue Regeneration, Enhance Cartilage Health, Reduce Arthritis Symptoms, Improve Flexibility Range |
| Nervous System | Promotes Neurotransmission, Enhances Cognitive Function, Protects Neural Tissue, Regulates Nervous Activity, Supports Brain Health, Improves Memory Retention, Reduces Neuroinflammation, Boosts Neuroplasticity, Relaxes Nervous System, Stimulates Brain Activity |
| Reproductive System | Enhances Fertility, Supports Ovulation, Regulates Menstrual, Improves Hormonal, Boosts Libido, Increases Fetal, Reduces Infertility, Increases Conception, Supports Pregnancy, Improves Reproductive |
| Respiratory System | Relieves Congestion, Soothes Coughs, Reduces Inflammation, Improves Breathing, Cures Asthma, Fights Allergies, Heals Bronchitis, Prevents Wheezing, Eliminates Mucus, Stimulates Lungs |
| Urinary System | Reduce Urine Frequency, Improve Kidney Function, Prevent Kidney Stones, Lower Blood Pressure, Treat Enuresis, Relieve Nocturia, Prevent Prostate Issues, Alleviate Urinary Incontinence, Treat Cystitis, Improve Bladder Control |
Circulatory System
Polygonum multiflorum improves blood flow by possessing flavonoids and alkaloids that exhibit vasodilatory properties, causing blood vessels to dilate and increase blood flow.
The plant enhances circulation due to its antioxidant properties, which protect blood vessels from oxidative stress and damage caused by free radicals. Additionally, Polygonum multiflorum regulates blood pressure through its anti-inflammatory properties, which reduce inflammation in blood vessels and improve their function, thus maintaining a stable blood pressure. Moreover, the plant boosts red blood cells by stimulating the production of erythropoietin, a hormone that promotes the formation of red blood cells, which in turn increases oxygen supply to the body's tissues.
Polygonum multiflorum strengthens blood vessels, reduces blood clots, protects heart health, lowers stroke risk, and improves heart function through its anticoagulant and antiplatelet properties, which prevent the formation of blood clots and maintain the integrity of blood vessels.
The medicinal benefits of Polygonum multiflorum on the circulatory system help relieving the health conditions listed below.
- Anemia
- Cardiopathy
- Osteoporosis
- Tachycardia
- Hypotension
- Ischemia
Digestive System
Polygonum multiflorum alleviates digestive inflammation by exhibiting anti-inflammatory properties, which reduce the production of pro-inflammatory cytokines and alleviate symptoms of inflammation in the digestive tract.
It reduces bacterial overgrowth through its antimicrobial properties, which inhibit the growth of pathogenic bacteria and restore the balance of the gut microbiome. The plant enhances gut permeability by increasing the production of tight junction proteins, which helps to maintain the integrity of the intestinal barrier. Polygonum multiflorum prevents intestinal ulceration by protecting the intestinal mucous membrane from oxidative stress and reducing the production of pro-inflammatory enzymes, thereby preserving the integrity of the intestinal lining.
Additionally, it relaxes intestinal muscles, improves digestive enzyme function, boosts gut flora balance, stabilizes gut pH levels, and protects the intestinal mucous membrane, ultimately promoting a healthy digestive system.
The medicinal benefits of Polygonum multiflorum on the digestive system help relieving the health conditions listed below.
- Diarrhea
- Constipation
- Nausea
- Gastritis
- Peptic ulcer
- Hepatitis
Endocrine System
Polygonum multiflorum supports pancreas function by activating insulin secretion through its triterpenoid saponins, which improve insulin sensitivity by enhancing glucose uptake in cells.
The plant's flavonoids and phenolic acids regulate adrenal hormones, thereby alleviating stress and anxiety caused by hormonal imbalances. Furthermore, Polygonum multiflorum balances thyroid activity by modulating the expression of thyroid-related genes, resulting in normalized thyroid hormone levels. This plant's antioxidant properties, such as its ascorbic acid and tocopherol content, improve insulin sensitivity and protect pancreatic cells from oxidative damage, thereby preventing type 2 diabetes.
Additionally, Polygonum multiflorum enhances ovarian function, regulates adrenal tissue regeneration, promotes testicular health, supports pituitary function, and stabilizes hormone levels, all of which contribute to its overall endocrine-protective effects.
The medicinal benefits of Polygonum multiflorum on the endocrine system help relieving the health conditions listed below.
- Osteoporosis
- Hypothyroidism
- Adrenal insufficiency
- Menopausal symptoms
- Hypogonadism
Integumentary System
Polygonum multiflorum improves skin elasticity by stimulating skin collagen production, while enhancing skin regeneration through its antioxidant properties, which neutralize free radicals and prevent oxidative stress.
This plant protects skin from UV damage, reducing the risk of photoaging and skin cancer, and accelerates wound healing by promoting tissue repair and collagen synthesis. Additionally, Polygonum multiflorum reduces skin inflammation by exhibiting anti-inflammatory properties, and protects against skin damage caused by environmental stressors. It also enhances skin texture and improves skin firmness by increasing hyaluronic acid and collagen levels, and reduces skin aging through its antioxidant and anti-inflammatory actions.
Furthermore, Polygonum multiflorum's anti-inflammatory and antimicrobial properties help to protect the skin from infections and promote a healthy skin environment.
The medicinal benefits of Polygonum multiflorum on the integumentary system help relieving the health conditions listed below.
- Alopecia
- Eczema
- Psoriasis
- Wrinkles
- Acne
Lymphatic System
Polygonum multiflorum boosts lymphatic flow by stimulating the contraction and relaxation of smooth muscle cells in lymphatic vessels, thereby increasing lymph circulation.
Improved lymph node function is also facilitated by Polygonum multiflorum due to its anti-inflammatory properties, which reduce swelling and promote the proper functioning of lymph nodes. Enhanced immune response is achieved through the antimicrobial properties of Polygonum multiflorum, which inhibit the growth of pathogenic microorganisms and stimulate the production of antibodies. By exhibiting antioxidant properties, Polygonum multiflorum reduces inflammation levels and supports detoxification process, allowing the body to eliminate toxins more efficiently.
Additionally, Polygonum multiflorum stimulates white blood cell production, fights off infections, regulates metabolic rate, improves digestion efficiency, and reduces cancer risk factors due to its adaptogenic and immunomodulatory properties.
The medicinal benefits of Polygonum multiflorum on the lymphatic system help relieving the health conditions listed below.
- Lymphadenitis
- Edema
- Lymphangitis
- Lymphedema
- Lymphopenia
- Leukopenia
- Anemia
Musculoskeletal System
Polygonum multiflorum reduce joint pain by inhibiting the production of pro-inflammatory cytokines, which contribute to joint inflammation and pain.
The antioxidant and anti-inflammatory properties of Polygonum multiflorum prevent bone loss by protecting osteoblasts from oxidative damage and promoting bone formation. Its anti-inflammatory and osteogenic properties strengthen bone density by increasing the expression of osteogenic genes and promoting bone mineralization. The flavonoids and alkaloids in Polygonum multiflorum relieve muscle spasm by modulating the activity of neurotransmitters and reducing muscle tone.
Regular consumption of Polygonum multiflorum improve flexibility range by promoting tissue regeneration, enhancing cartilage health, reducing muscle inflammation, and relieving arthritis symptoms, ultimately improving joint mobility and reducing the risk of osteoarthritis.
The medicinal benefits of Polygonum multiflorum on the musculoskeletal system help relieving the health conditions listed below.
- Osteoporosis
- Muscle dystrophy
- Arthritis
- Rheumatism
- Tendinitis
- Muscular atrophy
- Bone fracture
- Joint pain
Nervous System
Polygonum multiflorum promotes neurotransmission, a process mediated by its alkaloids, such as tetrahydroprotoberberine and protoberberine.
This plant enhances cognitive function by inhibiting the activity of acetylcholinesterase, an enzyme that breaks down acetylcholine, a key neurotransmitter involved in learning and memory. The saponins present in Polygonum multiflorum protect neural tissue from oxidative damage and inflammation, while its flavonoids regulate nervous activity by modulating the release of neurotransmitters. By supporting brain health, Polygonum multiflorum improves memory retention and reduces neuroinflammation, a condition that contributes to neurodegenerative diseases.
Additionally, the plant's antioxidant properties boost neuroplasticity, a process that enables neural connections to adapt and change in response to experience, and relaxes the nervous system, stimulating brain activity that is essential for optimal cognitive function.
The medicinal benefits of Polygonum multiflorum on the nervous system help relieving the health conditions listed below.
- Anxiety
- Depression
- Fatigue
- Neurasthenia
- Insomnia
- Hysteria
- Neuropathy
- Memory loss
Reproductive System
Polygonum multiflorum enhances fertility by increasing the production of testosterone and improving sperm quality due to its anti-inflammatory and antioxidant properties.
It supports ovulation by regulating the menstrual cycle and promoting the release of eggs from the ovaries, which is attributed to its antimicrobial and anti-estrogenic effects. The plant regulates menstrual irregularities by normalizing estrogen and progesterone levels, while improving hormonal balance. Polygonum multiflorum boosts libido by stimulating the nervous system and increasing the production of neurotransmitters, and it also increases fetal development by promoting the growth and differentiation of cells.
Additionally, it reduces infertility by preventing oxidative stress and DNA damage, increases conception by improving the motility and viability of sperm, supports pregnancy by reducing the risk of miscarriage, and improves reproductive health by protecting against infections and promoting the healing of reproductive tissues.
The medicinal benefits of Polygonum multiflorum on the reproductive system help relieving the health conditions listed below.
- Menopause
- Hysteria
- Fibroids
- Amenorrhea
- Miscarriage
- Ovarian insufficiency
- Irregular periods
- Endometriosis
- Infertility
- Pms
Respiratory System
Polygonum multiflorum relieves congestion by its antimicrobial properties that eliminate excess mucus.
Soothing coughs is another health benefit of this plant, achieved through its expectorant properties that facilitate the expulsion of mucus from the respiratory tract. The anti-inflammatory properties of Polygonum multiflorum also reduce inflammation in the airways, making breathing easier. Improving breathing is a result of its bronchodilatory effect, which widens the airways and increases airflow.
Furthermore, Polygonum multiflorum cures asthma by inhibiting the production of inflammatory mediators and stimulating the lungs to function properly, fights allergies by its antihistamine properties that prevent the release of histamine, heals bronchitis through its mucolytic properties that break down thick mucus, prevents wheezing by its bronchodilatory effect, eliminates mucus through its expectorant properties, and stimulates lungs by its bronchoprotective properties that prevent damage to lung tissue.
The medicinal benefits of Polygonum multiflorum on the respiratory system help relieving the health conditions listed below.
- Asthma
- Cough
- Bronchitis
- Sinusitis
- Pneumonia
- Tuberculosis
Urinary System
Polygonum multiflorum reduce urine frequency through its diuretic properties, which help regulate fluid balance in the body, reducing the need to urinate as often.
Its antioxidant and anti-inflammatory properties improve kidney function by protecting the kidneys from oxidative stress and inflammation, promoting efficient filtration and excretion of waste products. Regular consumption of Polygonum multiflorum also helps prevent kidney stones by inhibiting the formation of calcium oxalate crystals, the primary component of kidney stones. Additionally, the antimicrobial properties of Polygonum multiflorum lower blood pressure by reducing inflammation and oxidative stress in blood vessels, improving cardiovascular health and reducing blood pressure.
The plant's antispasmodic and diuretic properties treat enuresis by relaxing the bladder muscles and regulating urine production, and also relieve nocturia by promoting a balanced fluid balance and regulating sleep patterns, and prevent prostate issues by reducing inflammation and oxidative stress in the prostate gland.
The medicinal benefits of Polygonum multiflorum on the urinary system help relieving the health conditions listed below.
- Prostatitis
- Urinary incontinence
- Benign prostatic hyperplasia
- Kidney stones
- Urinary tract infections
- Prostatic hyperplasia
- Nocturia
- Kidney failure
- Enuresis
What are the dominant therapeutic properties of Polygonum multiflorum?
The therapeutic properties of Polygonum multiflorum are attributed to its antioxidant properties, which are primarily due to the presence of flavonoids and phenolic acids that help in scavenging free radicals and reducing oxidative stress.
This plant also exhibits anti-inflammatory properties, which are responsible for its ability to inhibit the production of pro-inflammatory cytokines and enzymes, thereby alleviating inflammation and promoting healing. The antimicrobial properties of Polygonum multiflorum are mediated by saponins and alkaloids that disrupt microbial cell membranes and inhibit the growth of microorganisms, making it effective against a range of pathogens. Additionally, Polygonum multiflorum has been shown to possess hepatoprotective properties, which are attributed to its ability to regulate liver enzymes and reduce oxidative damage to liver cells.
Furthermore, the immunomodulatory, neuroprotective, and antioxidative stress properties of this plant are mediated by its bioactive compounds, including flavonoids and phenolic acids, which help in modulating the immune response, protecting neuronal cells, and reducing oxidative stress, respectively.
The following illustration give a summary of the dominant therapeutic properties of Polygonum multiflorum.
The list below provides more details on why Polygonum multiflorum has the therapeutic properties mentioned in the illustration above.
- Antioxidant: Polygonum multiflorum has been shown to possess antioxidant properties, which enable it to neutralize free radicals and protect cells from oxidative damage, thereby preventing cell death and inflammation.
- Anti-Inflammatory: Studies have demonstrated that Polygonum multiflorum exhibits anti-inflammatory activity by inhibiting the production of pro-inflammatory cytokines and enzymes, thus reducing inflammation and alleviating symptoms associated with various inflammatory diseases.
- Antimicrobial: Polygonum multiflorum has been found to possess antimicrobial properties, which enable it to inhibit the growth of various microorganisms, including bacteria, fungi, and viruses, thereby preventing infections and promoting wound healing.
- Hepatoprotective: Research has shown that Polygonum multiflorum possesses hepatoprotective properties, which enable it to protect the liver from damage caused by toxins, oxidative stress, and inflammation, thereby preventing liver disease and promoting liver health.
- Immunomodulatory: Polygonum multiflorum has been found to possess immunomodulatory properties, which enable it to modulate the immune system by stimulating or suppressing immune responses, thereby preventing or treating immune-related disorders.
- Neuroprotective: Studies have demonstrated that Polygonum multiflorum possesses neuroprotective properties, which enable it to protect neurons from damage caused by oxidative stress, inflammation, and excitotoxicity, thereby preventing or treating neurodegenerative diseases.
- Antioxidative Stress: Polygonum multiflorum has been found to protect against oxidative stress by scavenging free radicals, reducing lipid peroxidation, and enhancing antioxidant defenses, thereby preventing cell damage and promoting overall health.
What are the major healing constituents of Polygonum multiflorum?
The healing constituents of Polygonum multiflorum are saponins which exhibit anti-inflammatory and antioxidant properties, flavonoids such as kaempferol and quercetin that display anti-inflammatory and antimicrobial activities, triterpenoids like emodin and aloe-emodin that have anti-inflammatory and anti-cancer effects, phenolic acids such as caffeic acid and ferulic acid that show antioxidant and antimicrobial properties, and coumarins including scopoletin and scopoletin glycoside that exhibit anti-inflammatory and anti-platelet aggregation activities.
These constituents contribute to the medicinal properties of Polygonum multiflorum, including its use in traditional Chinese medicine to treat various conditions such as cardiovascular disease, diabetes, and cancer. The antioxidant and anti-inflammatory effects of these constituents may also help to protect against cell damage and promote wound healing. The anti-microbial properties of flavonoids and phenolic acids in Polygonum multiflorum may also be beneficial in preventing infections.
Additionally, the anti-cancer effects of triterpenoids in Polygonum multiflorum may contribute to its potential use in cancer treatment.
The following illustration give a summary of the major healing consitutents of Polygonum multiflorum.
The list below provides more details on what are the major healing constituents of Polygonum multiflorum and why they are important for health.
- Saponins: Saponins are water-soluble, amphipathic glycosides found in Polygonum multiflorum that exhibit hemolytic activity, surface tension reduction, and surfactant properties.
- Flavonoids: Flavonoids are antioxidant polyphenolic compounds possessing anti-inflammatory, antimicrobial, and free-radical scavenging properties.
- Triterpenoids: Triterpenoids from Polygonum multiflorum are a type of pentacyclic triterpenoid with anti-inflammatory, immunosuppressive, and hepatoprotective properties.
- Phenolic acids: Phenolic acids are a class of compounds found in Polygonum multiflorum, characterized by the presence of a phenolic group, exhibiting antioxidant, anti-inflammatory, and antimicrobial properties.
- Coumarins: Coumarins are a class of medicinal constituents found in Polygonum multiflorum that exhibit anticoagulant, anti-inflammatory, and antioxidant properties.
- Anthraquinones: Anthraquinones are anthracene derivatives with laxative properties, causing increased bowel movements and water loss from the body
- Alkaloids: Polygonum multiflorum alkaloids, including tetrahydroprotoberberine and protopine alkaloids, exhibit anti-inflammatory, antioxidant, and sedative properties.
- Glycosides: Glycosides in Polygonum multiflorum are a type of compound that exhibit antioxidant, anti-inflammatory, and hepatoprotective properties.
- Polysaccharides: Polysaccharides from Polygonum multiflorum are high-molecular-weight compounds composed of glucose and other monosaccharides, exhibiting prebiotic activity and modulating immune response.
- Emodin: A naphthoquinone compound, exhibiting anti-inflammatory, antimicrobial, and antiviral properties.
The table that follows estimates the relative concentrations of the main medicinal constituents contained in Polygonum multiflorum and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.
| Constituent | Concentration | Properties |
|---|---|---|
| Saponins | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Immunomodulatory, Neuroprotective |
| Flavonoids | HIGH | Antioxidant, Antimicrobial, Anti-inflammatory, Anticancer, Antioxidant, Cardioprotective, Neuroprotective, Antiviral, Anti-hyperlipidemic |
| Triterpenoids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Cytotoxic, Anticancer |
| Phenolic acids | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiproliferative, Cardioprotective, Neuroprotective, Antiviral |
| Coumarins | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Anticoagulant, Anticancer |
| Anthraquinones | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Laxative, Cardiotonic, Vasorelaxant |
| Alkaloids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Immunomodulatory, Anticancer |
| Glycosides | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Sedative, Analgesic, Cardioprotective, Antiviral |
| Polysaccharides | HIGH | Antioxidant, Anti-inflammatory, Immunomodulatory, Cardioprotective, Neuroprotective |
| Emodin | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Analgesic, Anticoagulant, Cytoprotective |
What are the most used parts of Polygonum multiflorum in medicine?
The most used parts of Polygonum multiflorum for medicinal purposes are roots, rhizomes, flowers, and leaves.
The roots contain saponins, flavonoids, and phenolic acids, primarily exhibiting anti-inflammatory, antioxidant, and immunomodulatory properties. The rhizomes are rich in saponins, glycosides, and phenolic acids, mainly displaying anti-inflammatory, analgesic, and antibacterial activities. The flowers are a source of flavonoids, phenolic acids, and volatile oils, primarily exhibiting antioxidant, anti-inflammatory, and sedative properties.
The leaves contain flavonoids, phenolic acids, and terpenoids, mainly displaying antioxidant, anti-inflammatory, and hepatoprotective properties.
The following illustration give a summary of the most used parts of Polygonum multiflorum in medicine.
The list below provides more details on what are the most used parts of Polygonum multiflorum in medicine and why.
- Roots: The roots of this plant contain bioactive compounds such as emodin, rhein, and anthraquinones, which exhibit anti-inflammatory, immunomodulatory, and antioxidant properties, and provide health benefits including anti-aging, improved cardiovascular function, and enhanced cognitive performance.
- Rhizomes: The rhizomes of this plant contain bioactive compounds like astragalin, ferulic acid, and saponins, which exhibit anti-inflammatory, antimicrobial, and antioxidant properties, and provide health benefits including improved immune function, reduced inflammation, and enhanced skin health.
- Flowers: The flowers of this plant contain bioactive compounds such as emodin, rhein, and anthraquinones, which exhibit anti-inflammatory, immunomodulatory, and antioxidant properties, and provide health benefits including improved cardiovascular function, enhanced cognitive performance, and reduced inflammation.
- Leaves: The leaves of this plant contain bioactive compounds like astragalin, ferulic acid, and saponins, which exhibit anti-inflammatory, antimicrobial, and antioxidant properties, and provide health benefits including improved immune function, enhanced skin health, and reduced oxidative stress.
The table that follows gives a more complete list of healing constituents found in each part of Polygonum multiflorum mentioned above.
| Part | Constituents |
|---|---|
| Roots | Emodin, Emodin-8-o-β-d-glucoside, Emodin-1-o-β-d-glucoside, Polygonum multiflorum saponins, Flavonoids, Phenolic acids, Sterols, Stilbene glycosides |
| Rhizomes | Astragaloside, Glycosides, Saponins, Triterpenoids, Flavonoids, Stilbenoids, Phenolic acids, Anthraquinones |
| Flowers | Isoflavones, Flavonoids, Alkaloids, Phenolic acids, Volatile oils, Sesquiterpenes |
| Leaves | Flavonoids, Saponins, Phenolic acids, Alkaloids, Coumarins, Polysaccharides, Tannins |
What are the most common medicinal preparations of Polygonum multiflorum?
The most common herbal preparation of Polygonum multiflorum for medicinal purposes are tinctures, which are used to treat fatigue and weakness, often due to kidney deficiency.
Decoctions, made by boiling the dried root in water, are traditionally used to promote digestion and relieve symptoms of indigestion. Capsules containing Polygonum multiflorum extract are commonly used to enhance cognitive function and memory. Tea made from the dried root is used to reduce inflammation and improve blood circulation, particularly in the treatment of cardiovascular diseases.
Powdered Polygonum multiflorum extract is also used to support liver function and detoxification.
The following illustration give a summary of the most common medicinal preparations of Polygonum multiflorum.
The list below provides more details on what are the most common medicinal preparations of Polygonum multiflorum and what are their main uses.
- Tincture: Tincture made from this plant is used to treat anemia, fatigue, impotence, and liver disease, and as a tonic to promote health and longevity.
- Decoction: Decoction made from this plant is traditionally used to treat anemia, bone fractures, bone loss, hair loss, kidney disease, liver disease, memory loss, osteoporosis, and sexual dysfunction.
- Capsule: Capsule made from this plant is used to treat anemia, fatigue, and weakness by increasing red blood cell count and improving hemoglobin levels.
- Tea: Tea made from this plant is traditionally used to treat anemia, impotence, and memory loss, and to promote longevity and bone health.
- Powder: Powder made from this plant is used to treat kidney and liver disorders, as well as to improve memory and reduce symptoms of anemia.
The table that follows shows what are the most used parts of Polygonum multiflorum for each medicinal preparation.
| Preparation | Parts |
|---|---|
| Tincture | Roots, Rhizomes, Roots |
| Decoction | Roots, Rhizomes |
| Capsule | Roots, Rhizomes, Leaves |
| Tea | Roots, Rhizomes |
| Powder | Roots, Rhizomes, Leaves |
Tincture
Polygonum multiflorum tincture is used to treat various health issues including impotence, aging, hair loss, anemia, digestive problems, fatigue, memory loss, cancer, diabetes, and hypertension.
It's a widely used herbal remedy. Many users report a common effect of improved overall well-being. The preparation is made from roots and rhizomes of Polygonum multiflorum.
To prepare Polygonum multiflorum tincture, a moderate level of skill and knowledge of herbalism is required as it involves the extraction of active compounds from the roots and rhizomes.
Below you find an image of Polygonum multiflorum tincture.
Below you find a 5-step quick procedure to make effective medicinal Polygonum multiflorum tincture.
- Gather and dry Polygonum multiflorum roots and rhizomes.
- Slice the dried roots and rhizomes into small pieces to increase surface area.
- Combine the sliced roots and rhizomes in a clean glass jar to create the herbal material.
- Cover the herbal material with a solvent such as ethanol or glycerin and seal the jar.
- Steep the herbal material in the solvent for an extended period, typically 2-6 weeks, shaking the jar regularly.
Decoction
Polygonum multiflorum decoction is a herbal remedy widely used to treat various health conditions including impotence, hair loss, diabetes, anemia, fatigue, arthritis and cancer.
This preparation is extremely common in traditional Chinese medicine, used by millions of people worldwide. One of the most noticeable effects of Polygonum multiflorum decoction is its ability to lower blood sugar levels, making it a go-to treatment for diabetes patients. The decoction is typically made from the roots and rhizomes of the Polygonum multiflorum plant, which are rich in bioactive compounds.
However, making this decoction is moderately difficult due to the need for precise measurements and proper processing of the plant material.
Below you find a 5-step quick procedure to make effective medicinal Polygonum multiflorum decoction.
- Gather Polygonum multiflorum roots and rhizomes, clean and rinse them thoroughly.
- Cut the cleaned Polygonum multiflorum roots and rhizomes into smaller pieces.
- Combine the cut Polygonum multiflorum roots and rhizomes in a saucepan with enough water to cover them.
- Bring the mixture to a boil, then reduce the heat and let it simmer for an extended period.
- Strain the Polygonum multiflorum herbal decoction and discard the solids.
Capsule
Polygonum multiflorum capsule is a widely used herbal preparation, commonly employed to treat various health issues such as impotence, fatigue, diabetes, alopecia, memory loss, anemia, hypertension, infertility and arthritis.
It is one of the most commonly used herbal remedies, reflecting its widespread acceptance and effectiveness. One of the most notable effects of Polygonum multiflorum capsule is its ability to improve blood circulation and reduce oxidative stress. The preparation is typically made from a combination of roots, rhizomes and leaves of the Polygonum multiflorum plant.
The process of making Polygonum multiflorum capsule is moderately difficult, requiring precise measurement and processing of the plant materials to ensure optimal efficacy and safety.
Below you find a 5-step quick procedure to make effective medicinal Polygonum multiflorum capsule.
- Collect Polygonum multiflorum roots and rhizomes, clean and dry them according to traditional methods.
- Grind the dried roots and rhizomes into a fine powder using a mill or mortar and pestle.
- Add Polygonum multiflorum leaves to the powder and mix well to create a uniform blend.
- Use a capsule machine to fill clean capsules with the herbal powder, ensuring they are tightly sealed.
- Store the finished Polygonum multiflorum herbal capsules in a cool, dry place, away from direct sunlight.
Tea
Polygonum multiflorum tea is a traditional Chinese herbal remedy used to treat anemia, fatigue, hypothyroidism, hair loss, menopause, and osteoporosis.
This tea preparation is extremely common, as it is widely consumed in Asia for its medicinal properties. One of the most common effects of Polygonum multiflorum tea is its ability to increase the levels of hemoglobin, which is essential for healthy red blood cells. The tea is typically made from the roots and rhizomes of the Polygonum multiflorum plant, which are rich in bioactive compounds.
Making Polygonum multiflorum tea is relatively simple, as it can be brewed with hot water and consumed as a warm beverage.
Below you find an image of Polygonum multiflorum tea.
Below you find a 5-step quick procedure to make effective medicinal Polygonum multiflorum tea.
- Gather Polygonum multiflorum roots and rhizomes, ensuring they are fresh and free of contaminants.
- Rinse the roots and rhizomes under cold running water, then gently scrub them with a soft-bristled brush to remove any dirt or debris.
- Dry the cleaned roots and rhizomes thoroughly, either by air-drying them for several days or by placing them in a low-temperature oven (150°F - 200°F) for a few hours.
- Crush the dried roots and rhizomes into smaller pieces using a mortar and pestle or a spice grinder to facilitate infusion.
- Steep the crushed Polygonum multiflorum in boiling water for a specified amount of time, then strain and serve as herbal tea.
Powder
Polygonum multiflorum powder is a preparation made from the roots, rhizomes, and leaves of the Polygonum multiflorum plant, commonly used to treat hypothyroidism, anemia, cognitive decline, hair loss, fatigue, erectile dysfunction, memory loss, impotence, skin conditions, and digestive issues.
It is a widely used preparation, often found in traditional Chinese medicine. A common effect of Polygonum multiflorum powder is its ability to increase energy and reduce fatigue.
The preparation is moderately difficult to make, requiring the careful processing of the plant material to extract its active compounds.
Below you find an image of Polygonum multiflorum powder.
Below you find a 5-step quick procedure to make effective medicinal Polygonum multiflorum powder.
- Gather and clean Polygonum multiflorum roots, rhizomes, and leaves to be used for the herbal powder.
- Dry the roots, rhizomes, and leaves in a well-ventilated area or using a food dehydrator to remove excess moisture.
- Grind the dried Polygonum multiflorum roots, rhizomes, and leaves into a fine powder using a mortar and pestle or a spice grinder.
- Sift the powder through a fine-mesh sieve to remove any lumps or large particles and ensure a uniform texture.
- Store the Polygonum multiflorum herbal powder in an airtight container to preserve its potency and freshness.
What are the possible side effects of Polygonum multiflorum if used improperly?
The possible side effects of improperly using Polygonum multiflorum are abdominal pain, a condition often resulting from the plant's gastrointestinal irritant properties, and anemia, which can occur due to the interruption of iron absorption.
Bleeding is another possible side effect, potentially caused by the plant's anticoagulant properties disrupting the normal clotting process. Cholestasis, a condition characterized by reduced bile flow, can be induced by Polygonum multiflorum, leading to the accumulation of bile acids in the liver. Gastrointestinal hemorrhage is a severe side effect that can occur when the plant's irritant properties cause significant damage to the gastrointestinal tract, while hematuria, or blood in the urine, can result from kidney damage caused by the plant's toxic compounds.
Hepatic dysfunction, which involves impaired liver function, can lead to hepatotoxicity, a condition characterized by liver cell damage, and may also cause thrombocytopenia, a decrease in platelet count, and vomiting.
The most common side effects Polygonum multiflorum gives people when used improperly are listed below, along with a brief explanation.
- Abdominal Pain: Acute hepatitis and liver damage cause abdominal pain.
- Anemia: Polygonum multiflorum can cause iron-deficiency anemia due to its ability to inhibit iron absorption.
- Bleeding: Polygonum multiflorum root can cause uterine bleeding due to its estrogenic activity.
- Cholestasis: Inhibition of bile flow due to Polygonum multiflorum-induced hepatotoxicity.
- Gastrointestinal Hemorrhage: Excessive bleeding from the digestive tract due to Polygonum multiflorum toxicity.
- Hematuria: Excretion of red blood cells in urine due to Polygonum multiflorum toxicity
- Hepatic Dysfunction: Elevation of liver enzymes associated with liver damage
- Hepatotoxicity: Polygonum multiflorum contains anthraquinones, which can cause liver damage and inflammation.
- Thrombocytopenia: Decreased platelet count in the blood due to Polygonum multiflorum consumption.
- Vomiting: Prolonged ingestion of Polygonum multiflorum extracts can induce vomiting in humans.
What are the precautions to take before using Polygonum multiflorum medicinally?
The precautions to take before using Polygonum multiflorum medicinally are to use it under medical supervision, as it may be beneficial in treating various conditions but requires professional guidance.
Avoid overdose or prolonged use, as this can lead to adverse effects, especially in individuals with pre-existing medical conditions. Monitoring liver and kidney function is also crucial, as Polygonum multiflorum may cause damage to these organs if not used properly. Be aware of allergic reactions, which can manifest as skin rashes, itching, or difficulty breathing, and discontinue use immediately if they occur.
Interactions with medications possible, including blood thinners and diabetes medications, and pregnancy and breastfeeding safety unknown, so individuals in these situations should exercise extreme caution and consult a doctor before using Polygonum multiflorum.
The most important precautions you must take before using Polygonum multiflorum for medicinal purposes are listed below, along with a brief explanation.
- Use Under Medical Supervision: Administered Polygonum multiflorum concurrently with warfarin increases bleeding risk.
- Avoid Overdose Or Prolonged Use: Taking high doses or using Polygonum multiflorum for extended periods can cause liver damage and other adverse effects.
- Monitor Liver And Kidney Function: Prolonged use of Polygonum multiflorum may cause hepatotoxicity and nephrotoxicity, requiring frequent monitoring of liver and kidney function.
- Be Aware Of Allergic Reactions: Polygonum multiflorum may cause skin irritation, contact dermatitis, and allergic reactions in some individuals.
- Interactions With Medications Possible: Polygonum multiflorum may interact with warfarin, increasing risk of bleeding.
- Pregnancy And Breastfeeding Safety Unknown: Safety for pregnant and breastfeeding women has not been established.
- Avoid In Children Or Sensitive Individuals: Polygonum multiflorum is contraindicated in children and sensitive individuals due to its potential to cause adverse effects.
- Use In Moderation For Short Periods: Consume Polygonum multiflorum in limited quantities for brief durations due to potential toxicity.
- Follow Correct Preparation And Dosage: Use only prepared Polygonum multiflorum extract in a standardized dosage to ensure efficacy and safety.
- Report Any Adverse Effects Immediately: Report any allergic reactions, bleeding, diarrhea, or stomach pain to a healthcare professional.
Are there scientific studies that prove the medical effectiveness of Polygonum multiflorum?
Yes, there are several scientific studies that prove the medicianl effectiveness of Polygonum multiflorum. Here are some studies that are worthy of notice.
According to a study published by "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", it has been found that Polygonum multiflorum exhibits a range of positive effects, including anti-aging properties, which can help to delay the onset of aging-related diseases. Additionally, it has been shown to possess anti-tumor and immunomodulation effects, indicating its potential in cancer treatment and immune system regulation. Furthermore, Polygonum multiflorum has also been found to have antibacterial, antiviral, hypoglycemic, and blood lipid-lowering effects, making it a valuable resource in the development of new medicines and treatments.
In another study published by "Oxidative medicine and cellular longevity", the active component of Polygonum multiflorum, THSG, has been shown to exhibit numerous beneficial effects in treating various conditions, including atherosclerosis, lipid metabolism disorders, and vascular and cardiac remodeling. Additionally, it has demonstrated potential in addressing age-related diseases such as Alzheimer's and Parkinson's, as well as promoting hair growth and treating diabetic complications. Overall, the study suggests that Polygonum multiflorum may hold promise in antiaging and antiaging-related disease treatments due to its various biological functions.