South China ginseng

Panax notoginseng · Accepted scientific name

Scientific literature: Very Extensive (1629 studies) · ★★★★★

South China ginseng, scientifically known as Panax notoginseng, is a highly prized medicinal root celebrated in traditional Chinese medicine. Renowned for its adaptogenic properties, it is used to enhance vitality, improve circulation, and reduce inflammation. This potent botanical serves as a cornerstone for promoting overall wellness and longevity.

Family
Araliaceae
Native range
Asia-Temperate
Parts used
Root · Leaf
Common names
South China Ginseng · Notoginseng · 3 more
Scientific synonyms
Panax Pseudoginseng Var. Notoginseng · Aralia Quinquefolia Var. Notoginseng

Names and Synonyms

Common Names

Scientific Names

Accepted name

Panax notoginseng

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it is placed in the order Apiales and the family Araliaceae. Finally, it is categorized under the genus Panax, specifically as the species Panax notoginseng.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Apiales
Family Araliaceae
Genus Panax

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant is primarily distributed across specific regions of East and Southeast Asia. In China, its presence is noted throughout the South-Central territories. It is also found extensively within the Southeast regions of China. Beyond Chinese borders, the species extends into the Indo-China peninsula. Specifically, it can be located within the geographical boundaries of Vietnam.

Region Area
China China South-Central
China China Southeast
Indo-China Vietnam

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Panax notoginseng is characterized by its classification as a hemicryptophyte, a life form where the perennating buds are located at or just below the soil surface, protected by the leaf litter or soil layer. This survival strategy allows the plant to endure seasonal fluctuations by maintaining its vital organs at the ground level, facilitating a perennial growth cycle. As a hemicryptophyte, it functions through a developmental pattern that balances underground storage with seasonal aerial emergence, ensuring resilience against environmental stressors. This life history pattern enables the plant to establish a robust presence in its natural habitat, utilizing its specialized physiological structures to navigate through varying climatic conditions over multiple growing seasons.

Life form :
hemicryptophyte

Morphology

The morphology of Panax notoginseng is characterized by its growth habit as a non-climbing, terrestrial herb. Unlike climbing species, it is strictly self-supporting and does not exhibit any climber tendencies, whether obligatory or facultative. It functions as an independent organism, showing no parasitic behavior toward other plants. As a terrestrial plant, it lacks epiphyte qualities, growing entirely within the soil substrate rather than on other vegetation. In terms of its structural composition, the plant is categorized as non-woody, consisting of succulent or herbaceous tissues rather than woody stems, which is typical for its perennial herbaceous lifecycle.

Climber :
self-supporting
Epiphyte :
terrestrial
Parasite :
independent
Woodiness :
woody

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Panax notoginseng has 7 reported plant parts identified across 113 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf, flower, stem, rhizome.

Plant parts reported in Panax notoginseng
Plant part Supporting sources Consensus
Root 60 supporting sources ★★★★★
Leaf 20 supporting sources ★★★★★
Flower 13 supporting sources ★★★★★
Stem 11 supporting sources ★★★★★
Rhizome 6 supporting sources ★★★☆☆
Seed 2 supporting sources ★☆☆☆☆
Fruit 1 supporting sources ★☆☆☆☆

Root

  1. Current microbiology
  2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  3. Journal of fungi (Basel, Switzerland)
  4. Current protein & peptide science
  5. BMC plant biology
View 55 additional sources
  1. Phytochemistry
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Chinese medicine
  4. Life sciences
  5. Frontiers in plant science
  6. Plant cell reports
  7. Environmental microbiome
  8. Journal of environmental quality
  9. DNA sequence : the journal of DNA sequencing and mapping
  10. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  11. BMC genomics
  12. Journal of ginseng research
  13. Journal of natural products
  14. Journal of ethnopharmacology
  15. Life (Basel, Switzerland)
  16. Ecotoxicology and environmental safety
  17. iScience
  18. Cells
  19. Biological & pharmaceutical bulletin
  20. Natural product research
  21. Journal of the science of food and agriculture
  22. Chinese journal of biotechnology
  23. PloS one
  24. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
  25. Plant disease
  26. Frontiers in nutrition
  27. BMC microbiology
  28. Functional plant biology : FPB
  29. Frontiers in microbiology
  30. Biotechnology and applied biochemistry
  31. Drug discoveries & therapeutics
  32. Guang pu xue yu guang pu fen xi = Guang pu
  33. Journal of plant physiology
  34. Molecular plant pathology
  35. Rapid communications in mass spectrometry : RCM
  36. Journal of pharmaceutical and biomedical analysis
  37. Biomedical chromatography : BMC
  38. Plant physiology and biochemistry : PPB
  39. European journal of pharmacology
  40. Molecules (Basel, Switzerland)
  41. Huan jing ke xue= Huanjing kexue
  42. Plants (Basel, Switzerland)
  43. Planta medica
  44. Natural products and bioprospecting
  45. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  46. Food & function
  47. Plant, cell & environment
  48. Drug metabolism and disposition: the biological fate of chemicals
  49. Phytochemical analysis : PCA
  50. Chemistry & biodiversity
  51. Food chemistry: X
  52. Vaccine
  53. Organic & biomolecular chemistry
  54. PeerJ
  55. Chemosphere

Leaf

  1. Steroids
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Journal of ginseng research
  4. Analytical and bioanalytical chemistry
  5. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
View 15 additional sources
  1. BMC genomics
  2. Analytica chimica acta
  3. Chinese journal of biotechnology
  4. Frontiers in nutrition
  5. Oxidative medicine and cellular longevity
  6. Molecules (Basel, Switzerland)
  7. Journal of chromatography. A
  8. Organic & biomolecular chemistry
  9. Huan jing ke xue= Huanjing kexue
  10. Journal of food science
  11. Medicinal chemistry (Shariqah (United Arab Emirates))
  12. Food chemistry: X
  13. Journal of agricultural and food chemistry
  14. The American journal of Chinese medicine
  15. PeerJ

Flower

  1. Phytochemistry
  2. BMC genomics
  3. Journal of natural products
  4. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  5. Molecules (Basel, Switzerland)
View 8 additional sources
  1. Chinese journal of biotechnology
  2. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
  3. Huan jing ke xue= Huanjing kexue
  4. The American journal of Chinese medicine
  5. Food & function
  6. BMC plant biology
  7. Journal of agricultural and food chemistry
  8. Pesticide biochemistry and physiology

Stem

  1. Journal of ginseng research
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  3. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  4. Cells
  5. Chinese journal of biotechnology
View 6 additional sources
  1. Frontiers in nutrition
  2. Oxidative medicine and cellular longevity
  3. Huan jing ke xue= Huanjing kexue
  4. Journal of food science
  5. Food chemistry: X
  6. PeerJ

Rhizome

  1. Phytochemistry
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Functional plant biology : FPB
  4. Guang pu xue yu guang pu fen xi = Guang pu
  5. Journal of ginseng research
View 1 additional sources
  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Seed

  1. Environmental microbiome
  2. Functional plant biology : FPB

Fruit

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Chemicals

Panax notoginseng has 294 reported phytochemicals identified across 113 scientific publications and several other databases. The most consistently reported chemicals include Saponins, Notoginsenoside R1, Ginsenosides, SAPONIN, PANAX NOTOGINSENG SAPONINS.

Chemicals reported in Panax notoginseng
Chemical Supporting sources Consensus
Saponins 34 supporting sources ★★★★★
Notoginsenoside R1 30 supporting sources ★★★★★
Ginsenosides 27 supporting sources ★★★★★
SAPONIN 21 supporting sources ★★★★★
PANAX NOTOGINSENG SAPONINS 19 supporting sources ★★★★★
RB1 19 supporting sources ★★★★★
RG1 19 supporting sources ★★★★★
Ginsenoside RG1 17 supporting sources ★★★★★
Ginsenoside rb1 17 supporting sources ★★★★★
RD 17 supporting sources ★★★★★

Saponins

  1. Zhongguo yao li xue bao = Acta pharmacologica Sinica
  2. Current protein & peptide science
  3. BMC complementary and alternative medicine
  4. Yao xue xue bao = Acta pharmaceutica Sinica
  5. Phytochemistry
View 29 additional sources
  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Analytical and bioanalytical chemistry
  3. Environmental microbiome
  4. Vaccine
  5. Life (Basel, Switzerland)
  6. Journal of the science of food and agriculture
  7. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  8. Chinese journal of biotechnology
  9. Plant cell reports
  10. BMC plant biology
  11. Acta pharmacologica Sinica
  12. Biotechnology and applied biochemistry
  13. Guang pu xue yu guang pu fen xi = Guang pu
  14. Journal of ginseng research
  15. Journal of pharmaceutical and biomedical analysis
  16. Chemistry & biodiversity
  17. Journal of ethnopharmacology
  18. Journal of plant physiology
  19. Virology
  20. Frontiers in plant science
  21. Phytomedicine : international journal of phytotherapy and phytopharmacology
  22. Food & function
  23. Natural product research
  24. Frontiers in nutrition
  25. Plant physiology and biochemistry : PPB
  26. Plant, cell & environment
  27. Frontiers in microbiology
  28. PeerJ
  29. Microbial biotechnology

Notoginsenoside R1

  1. PloS one
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  4. Genes
  5. Gene
View 25 additional sources
  1. Journal of ginseng research
  2. Yao xue xue bao = Acta pharmaceutica Sinica
  3. Journal of agricultural and food chemistry
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  5. Journal of medicinal food
  6. Frontiers in pharmacology
  7. Scientific reports
  8. Biotechnology, biotechnological equipment
  9. Chinese journal of traumatology = Zhonghua chuang shang za zhi
  10. International archives of medicine
  11. Molecules (Basel, Switzerland)
  12. Acta cirurgica brasileira
  13. Frontiers in nutrition
  14. International immunopharmacology
  15. Chinese medicine
  16. Drug metabolism and disposition: the biological fate of chemicals
  17. Metabolic engineering
  18. Journal of separation science
  19. Phytomedicine : international journal of phytotherapy and phytopharmacology
  20. Oncotarget
  21. Free radical research
  22. European journal of pharmacology
  23. British journal of pharmacology
  24. Phytochemical analysis : PCA
  25. Cells

Ginsenosides

  1. Dr. Duke
  2. Current protein & peptide science
  3. BMC genomics
  4. Oncology letters
  5. European journal of medicinal chemistry
View 22 additional sources
  1. Life (Basel, Switzerland)
  2. Analytica chimica acta
  3. Yao xue xue bao = Acta pharmaceutica Sinica
  4. Frontiers in pharmacology
  5. Journal of the science of food and agriculture
  6. Journal of advanced research
  7. Medicinal research reviews
  8. Journal of chromatography. A
  9. Regulatory toxicology and pharmacology : RTP
  10. Phytomedicine : international journal of phytotherapy and phytopharmacology
  11. Plants (Basel, Switzerland)
  12. Cells
  13. Journal of ginseng research
  14. Journal of food science
  15. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  16. Molecular and cellular probes
  17. Drug metabolism and disposition: the biological fate of chemicals
  18. Phytochemical analysis : PCA
  19. Horticulture research
  20. BMC plant biology
  21. Food chemistry: X
  22. Microbial biotechnology

SAPONIN

  1. Current microbiology
  2. BMC plant biology
  3. Chinese medicine
  4. Environmental microbiome
  5. Journal of the American Heart Association
View 16 additional sources
  1. Journal of medicinal food
  2. Ecotoxicology and environmental safety
  3. Chinese journal of biotechnology
  4. British journal of pharmacology
  5. Plant cell reports
  6. Phytochemistry
  7. Frontiers in plant science
  8. Biotechnology and applied biochemistry
  9. Plant physiology and biochemistry : PPB
  10. Plants (Basel, Switzerland)
  11. Plant communications
  12. Journal of ginseng research
  13. Phytochemical analysis : PCA
  14. Food chemistry: X
  15. The American journal of Chinese medicine
  16. Pesticide biochemistry and physiology

PANAX NOTOGINSENG SAPONINS

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Frontiers in plant science
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Zhongguo yao li xue bao = Acta pharmacologica Sinica
  5. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
View 14 additional sources
  1. Acta pharmacologica Sinica
  2. Journal of ethnopharmacology
  3. Journal of plant physiology
  4. Journal of chromatography. A
  5. Chinese journal of natural medicines
  6. Food & function
  7. Yao xue xue bao = Acta pharmaceutica Sinica
  8. Drug design, development and therapy
  9. Journal of ginseng research
  10. Molecules (Basel, Switzerland)
  11. Annals of vascular surgery
  12. Plant cell reports
  13. Phytotherapy research : PTR
  14. Nan fang yi ke da xue xue bao = Journal of Southern Medical University

RB1

  1. Chinese medicine
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  3. Journal of ginseng research
  4. Journal of medicinal food
  5. Journal of chromatography. A
View 14 additional sources
  1. Journal of agricultural and food chemistry
  2. Yao xue xue bao = Acta pharmaceutica Sinica
  3. Zhongguo yao li xue bao = Acta pharmacologica Sinica
  4. Talanta
  5. Journal of separation science
  6. Hypertension research : official journal of the Japanese Society of Hypertension
  7. Journal of ethnopharmacology
  8. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  9. Phytomedicine : international journal of phytotherapy and phytopharmacology
  10. Natural product research
  11. Drug metabolism and disposition: the biological fate of chemicals
  12. Phytochemical analysis : PCA
  13. Pesticide biochemistry and physiology
  14. Microbial biotechnology

RG1

  1. Journal of fungi (Basel, Switzerland)
  2. Chinese medicine
  3. Frontiers in plant science
  4. Journal of AOAC International
  5. Gene
View 14 additional sources
  1. Pharmacological research
  2. Yao xue xue bao = Acta pharmaceutica Sinica
  3. Molecules (Basel, Switzerland)
  4. Chinese journal of biotechnology
  5. Journal of chromatography. A
  6. Journal of agricultural and food chemistry
  7. Zhongguo yao li xue bao = Acta pharmacologica Sinica
  8. Talanta
  9. Hypertension research : official journal of the Japanese Society of Hypertension
  10. Journal of ethnopharmacology
  11. Phytomedicine : international journal of phytotherapy and phytopharmacology
  12. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  13. Drug metabolism and disposition: the biological fate of chemicals
  14. Microbial biotechnology

Ginsenoside RG1

  1. PloS one
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. Genes
  5. Frontiers in plant science
View 12 additional sources
  1. Yao xue xue bao = Acta pharmaceutica Sinica
  2. Cells
  3. Acta pharmacologica Sinica
  4. Biotechnology, biotechnological equipment
  5. International archives of medicine
  6. Chinese medicine
  7. Journal of ginseng research
  8. Natural products and bioprospecting
  9. Metabolic engineering
  10. Journal of ethnopharmacology
  11. Phytochemical analysis : PCA
  12. Microbial biotechnology

Ginsenoside rb1

  1. PloS one
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. Genes
  5. Yao xue xue bao = Acta pharmaceutica Sinica
View 12 additional sources
  1. Biotechnology, biotechnological equipment
  2. Journal of the science of food and agriculture
  3. International archives of medicine
  4. Chinese medicine
  5. Journal of ginseng research
  6. Frontiers in pharmacology
  7. Folia microbiologica
  8. Cells
  9. Journal of ethnopharmacology
  10. Molecular and cellular probes
  11. Molecules (Basel, Switzerland)
  12. Microbial biotechnology

RD

  1. Journal of fungi (Basel, Switzerland)
  2. Chinese medicine
  3. Gene
  4. Journal of ginseng research
  5. Journal of medicinal food
View 12 additional sources
  1. Molecules (Basel, Switzerland)
  2. Journal of chromatography. A
  3. Journal of agricultural and food chemistry
  4. Talanta
  5. Journal of separation science
  6. Folia microbiologica
  7. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  8. Phytomedicine : international journal of phytotherapy and phytopharmacology
  9. Natural product research
  10. Drug metabolism and disposition: the biological fate of chemicals
  11. Frontiers in microbiology
  12. Microbial biotechnology

Activities

Panax notoginseng has 227 reported activities identified across 113 scientific publications and several other databases. The most consistently reported activities include Neuroprotective, Antioxidant, Antifungal, Antitumor, Cardioprotective.

Activities reported in Panax notoginseng
Activity Supporting sources Consensus
Neuroprotective 10 supporting sources ★★★★★
Antioxidant 9 supporting sources ★★★★☆
Antifungal 4 supporting sources ★★☆☆☆
Antitumor 4 supporting sources ★★☆☆☆
Cardioprotective 4 supporting sources ★★☆☆☆
Anticancer 3 supporting sources ★★☆☆☆
Antidepressant 3 supporting sources ★★☆☆☆
Antidiabetic 3 supporting sources ★★☆☆☆
Antihypertensive 3 supporting sources ★★☆☆☆
Cytotoxic 3 supporting sources ★★☆☆☆

Neuroprotective

  1. Dr. Duke
  2. Journal of ginseng research
  3. Heliyon
  4. European journal of medicinal chemistry
  5. Frontiers in pharmacology
View 5 additional sources
  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Cells
  3. Oncotarget
  4. Phytotherapy research : PTR
  5. Molecules (Basel, Switzerland)

Antioxidant

  1. Dr. Duke
  2. Journal of medicinal food
  3. Journal of ethnopharmacology
  4. Free radical research
  5. Plants (Basel, Switzerland)
View 4 additional sources
  1. Acta pharmacologica Sinica
  2. Chemistry & biodiversity
  3. Food chemistry: X
  4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Antifungal

  1. Biochemical and biophysical research communications
  2. The international journal of biochemistry & cell biology
  3. Planta medica
  4. Journal of ginseng research

Antitumor

  1. Dr. Duke
  2. Journal of agricultural and food chemistry
  3. Molecules (Basel, Switzerland)
  4. Journal of ethnopharmacology

Cardioprotective

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. European journal of medicinal chemistry
  3. Frontiers in pharmacology
  4. Molecules (Basel, Switzerland)

Anticancer

  1. Dr. Duke
  2. European journal of medicinal chemistry
  3. Current medicinal chemistry

Antidepressant

  1. Dr. Duke
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology
  3. Plants (Basel, Switzerland)

Antidiabetic

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Journal of ethnopharmacology

Antihypertensive

  1. Dr. Duke
  2. Clinical and experimental pharmacology & physiology. Supplement
  3. Food chemistry: X

Cytotoxic

  1. Dr. Duke
  2. Journal of ginseng research
  3. Natural products and bioprospecting

Medicinal Uses

Panax notoginseng has 119 reported medicinal uses identified across 113 scientific publications and several other databases. The most consistently reported uses include cardiovascular diseases, apoptosis, cancer, inflammation, obesity.

Most Reported Uses

Use Sources Consensus
cardiovascular diseases Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 10 sources) ★★★★★
apoptosis Biomolecules (and other 9 sources) ★★★★☆
cancer Journal of medicinal food (and other 9 sources) ★★★★☆
inflammation Frontiers in pharmacology (and other 9 sources) ★★★★☆
obesity Journal of the American Heart Association (and other 7 sources) ★★★★☆
oxidative stress Oxidative medicine and cellular longevity (and other 7 sources) ★★★★☆
ischemic stroke Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 6 sources) ★★★☆☆
atherosclerosis Chinese medicine (and other 4 sources) ★★☆☆☆
myocardial infarction Chinese journal of traumatology = Zhonghua chuang shang za zhi (and other 4 sources) ★★☆☆☆
platelet aggregation Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 4 sources) ★★☆☆☆

Preparations

Preparations Sources Consensus
Notoginsenoside R1 Frontiers in pharmacology (and other 4 sources) ★★☆☆☆
roots Life sciences (and other 4 sources) ★★☆☆☆
total saponins Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 4 sources) ★★☆☆☆
Panax notoginseng saponins Acta pharmacologica Sinica (and other 3 sources) ★★☆☆☆
Panax notoginseng saponins (PNS) Acta pharmacologica Sinica (and other 3 sources) ★★☆☆☆
Radix Notoginseng Frontiers in nutrition (and other 2 sources) ★☆☆☆☆
Rg1 Zhongguo yao li xue bao = Acta pharmacologica Sinica (and other 2 sources) ★☆☆☆☆
extracellular vesicles Journal of nanobiotechnology (and other 2 sources) ★☆☆☆☆
extracts Frontiers in pharmacology (and other 2 sources) ★☆☆☆☆
4 kinds of acid polysaccharide BMC cancer (and other 1 sources) ★☆☆☆☆