South China ginseng
Panax notoginseng · Accepted scientific name
Scientific literature: Very Extensive (1629 studies) · ★★★★★
South China ginseng, scientifically known as Panax notoginseng, is a highly prized medicinal root celebrated in traditional Chinese medicine. Renowned for its adaptogenic properties, it is used to enhance vitality, improve circulation, and reduce inflammation. This potent botanical serves as a cornerstone for promoting overall wellness and longevity.
- Family
- Araliaceae
- Native range
- Asia-Temperate
- Parts used
- Root · Leaf
- Common names
- South China Ginseng · Notoginseng · 3 more
- Scientific synonyms
- Panax Pseudoginseng Var. Notoginseng · Aralia Quinquefolia Var. Notoginseng
Names and Synonyms
Common Names
- South China ginseng
- notoginseng
- san-qi ginseng
- sanchi ginseng
- tienchi ginseng
Scientific Names
Accepted name
Panax notoginsengSynonyms
- Panax pseudoginseng var. notoginseng
- Aralia quinquefolia var. notoginseng
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it is placed in the order Apiales and the family Araliaceae. Finally, it is categorized under the genus Panax, specifically as the species Panax notoginseng.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Apiales |
| Family | Araliaceae |
| Genus | Panax |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant is primarily distributed across specific regions of East and Southeast Asia. In China, its presence is noted throughout the South-Central territories. It is also found extensively within the Southeast regions of China. Beyond Chinese borders, the species extends into the Indo-China peninsula. Specifically, it can be located within the geographical boundaries of Vietnam.
| Region | Area |
|---|---|
| China | China South-Central |
| China | China Southeast |
| Indo-China | Vietnam |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Panax notoginseng is characterized by its classification as a hemicryptophyte, a life form where the perennating buds are located at or just below the soil surface, protected by the leaf litter or soil layer. This survival strategy allows the plant to endure seasonal fluctuations by maintaining its vital organs at the ground level, facilitating a perennial growth cycle. As a hemicryptophyte, it functions through a developmental pattern that balances underground storage with seasonal aerial emergence, ensuring resilience against environmental stressors. This life history pattern enables the plant to establish a robust presence in its natural habitat, utilizing its specialized physiological structures to navigate through varying climatic conditions over multiple growing seasons.
- Life form :
- hemicryptophyte
Morphology
The morphology of Panax notoginseng is characterized by its growth habit as a non-climbing, terrestrial herb. Unlike climbing species, it is strictly self-supporting and does not exhibit any climber tendencies, whether obligatory or facultative. It functions as an independent organism, showing no parasitic behavior toward other plants. As a terrestrial plant, it lacks epiphyte qualities, growing entirely within the soil substrate rather than on other vegetation. In terms of its structural composition, the plant is categorized as non-woody, consisting of succulent or herbaceous tissues rather than woody stems, which is typical for its perennial herbaceous lifecycle.
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Parasite :
- independent
- Woodiness :
- woody
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Panax notoginseng has 7 reported plant parts identified across 113 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf, flower, stem, rhizome.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 60 supporting sources | ★★★★★ |
| Leaf | 20 supporting sources | ★★★★★ |
| Flower | 13 supporting sources | ★★★★★ |
| Stem | 11 supporting sources | ★★★★★ |
| Rhizome | 6 supporting sources | ★★★☆☆ |
| Seed | 2 supporting sources | ★☆☆☆☆ |
| Fruit | 1 supporting sources | ★☆☆☆☆ |
Root
- Current microbiology
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Journal of fungi (Basel, Switzerland)
- Current protein & peptide science
- BMC plant biology
View 55 additional sources
- Phytochemistry
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Chinese medicine
- Life sciences
- Frontiers in plant science
- Plant cell reports
- Environmental microbiome
- Journal of environmental quality
- DNA sequence : the journal of DNA sequencing and mapping
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- BMC genomics
- Journal of ginseng research
- Journal of natural products
- Journal of ethnopharmacology
- Life (Basel, Switzerland)
- Ecotoxicology and environmental safety
- iScience
- Cells
- Biological & pharmaceutical bulletin
- Natural product research
- Journal of the science of food and agriculture
- Chinese journal of biotechnology
- PloS one
- Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
- Plant disease
- Frontiers in nutrition
- BMC microbiology
- Functional plant biology : FPB
- Frontiers in microbiology
- Biotechnology and applied biochemistry
- Drug discoveries & therapeutics
- Guang pu xue yu guang pu fen xi = Guang pu
- Journal of plant physiology
- Molecular plant pathology
- Rapid communications in mass spectrometry : RCM
- Journal of pharmaceutical and biomedical analysis
- Biomedical chromatography : BMC
- Plant physiology and biochemistry : PPB
- European journal of pharmacology
- Molecules (Basel, Switzerland)
- Huan jing ke xue= Huanjing kexue
- Plants (Basel, Switzerland)
- Planta medica
- Natural products and bioprospecting
- Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
- Food & function
- Plant, cell & environment
- Drug metabolism and disposition: the biological fate of chemicals
- Phytochemical analysis : PCA
- Chemistry & biodiversity
- Food chemistry: X
- Vaccine
- Organic & biomolecular chemistry
- PeerJ
- Chemosphere
Leaf
- Steroids
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Journal of ginseng research
- Analytical and bioanalytical chemistry
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
View 15 additional sources
- BMC genomics
- Analytica chimica acta
- Chinese journal of biotechnology
- Frontiers in nutrition
- Oxidative medicine and cellular longevity
- Molecules (Basel, Switzerland)
- Journal of chromatography. A
- Organic & biomolecular chemistry
- Huan jing ke xue= Huanjing kexue
- Journal of food science
- Medicinal chemistry (Shariqah (United Arab Emirates))
- Food chemistry: X
- Journal of agricultural and food chemistry
- The American journal of Chinese medicine
- PeerJ
Flower
- Phytochemistry
- BMC genomics
- Journal of natural products
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Molecules (Basel, Switzerland)
View 8 additional sources
- Chinese journal of biotechnology
- Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
- Huan jing ke xue= Huanjing kexue
- The American journal of Chinese medicine
- Food & function
- BMC plant biology
- Journal of agricultural and food chemistry
- Pesticide biochemistry and physiology
Stem
- Journal of ginseng research
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Cells
- Chinese journal of biotechnology
View 6 additional sources
- Frontiers in nutrition
- Oxidative medicine and cellular longevity
- Huan jing ke xue= Huanjing kexue
- Journal of food science
- Food chemistry: X
- PeerJ
Rhizome
- Phytochemistry
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Functional plant biology : FPB
- Guang pu xue yu guang pu fen xi = Guang pu
- Journal of ginseng research
View 1 additional sources
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Seed
- Environmental microbiome
- Functional plant biology : FPB
Fruit
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Chemicals
Panax notoginseng has 294 reported phytochemicals identified across 113 scientific publications and several other databases. The most consistently reported chemicals include Saponins, Notoginsenoside R1, Ginsenosides, SAPONIN, PANAX NOTOGINSENG SAPONINS.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Saponins | 34 supporting sources | ★★★★★ |
| Notoginsenoside R1 | 30 supporting sources | ★★★★★ |
| Ginsenosides | 27 supporting sources | ★★★★★ |
| SAPONIN | 21 supporting sources | ★★★★★ |
| PANAX NOTOGINSENG SAPONINS | 19 supporting sources | ★★★★★ |
| RB1 | 19 supporting sources | ★★★★★ |
| RG1 | 19 supporting sources | ★★★★★ |
| Ginsenoside RG1 | 17 supporting sources | ★★★★★ |
| Ginsenoside rb1 | 17 supporting sources | ★★★★★ |
| RD | 17 supporting sources | ★★★★★ |
Saponins
- Zhongguo yao li xue bao = Acta pharmacologica Sinica
- Current protein & peptide science
- BMC complementary and alternative medicine
- Yao xue xue bao = Acta pharmaceutica Sinica
- Phytochemistry
View 29 additional sources
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Analytical and bioanalytical chemistry
- Environmental microbiome
- Vaccine
- Life (Basel, Switzerland)
- Journal of the science of food and agriculture
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Chinese journal of biotechnology
- Plant cell reports
- BMC plant biology
- Acta pharmacologica Sinica
- Biotechnology and applied biochemistry
- Guang pu xue yu guang pu fen xi = Guang pu
- Journal of ginseng research
- Journal of pharmaceutical and biomedical analysis
- Chemistry & biodiversity
- Journal of ethnopharmacology
- Journal of plant physiology
- Virology
- Frontiers in plant science
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Food & function
- Natural product research
- Frontiers in nutrition
- Plant physiology and biochemistry : PPB
- Plant, cell & environment
- Frontiers in microbiology
- PeerJ
- Microbial biotechnology
Notoginsenoside R1
- PloS one
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Genes
- Gene
View 25 additional sources
- Journal of ginseng research
- Yao xue xue bao = Acta pharmaceutica Sinica
- Journal of agricultural and food chemistry
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of medicinal food
- Frontiers in pharmacology
- Scientific reports
- Biotechnology, biotechnological equipment
- Chinese journal of traumatology = Zhonghua chuang shang za zhi
- International archives of medicine
- Molecules (Basel, Switzerland)
- Acta cirurgica brasileira
- Frontiers in nutrition
- International immunopharmacology
- Chinese medicine
- Drug metabolism and disposition: the biological fate of chemicals
- Metabolic engineering
- Journal of separation science
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Oncotarget
- Free radical research
- European journal of pharmacology
- British journal of pharmacology
- Phytochemical analysis : PCA
- Cells
Ginsenosides
- Dr. Duke
- Current protein & peptide science
- BMC genomics
- Oncology letters
- European journal of medicinal chemistry
View 22 additional sources
- Life (Basel, Switzerland)
- Analytica chimica acta
- Yao xue xue bao = Acta pharmaceutica Sinica
- Frontiers in pharmacology
- Journal of the science of food and agriculture
- Journal of advanced research
- Medicinal research reviews
- Journal of chromatography. A
- Regulatory toxicology and pharmacology : RTP
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Plants (Basel, Switzerland)
- Cells
- Journal of ginseng research
- Journal of food science
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Molecular and cellular probes
- Drug metabolism and disposition: the biological fate of chemicals
- Phytochemical analysis : PCA
- Horticulture research
- BMC plant biology
- Food chemistry: X
- Microbial biotechnology
SAPONIN
- Current microbiology
- BMC plant biology
- Chinese medicine
- Environmental microbiome
- Journal of the American Heart Association
View 16 additional sources
- Journal of medicinal food
- Ecotoxicology and environmental safety
- Chinese journal of biotechnology
- British journal of pharmacology
- Plant cell reports
- Phytochemistry
- Frontiers in plant science
- Biotechnology and applied biochemistry
- Plant physiology and biochemistry : PPB
- Plants (Basel, Switzerland)
- Plant communications
- Journal of ginseng research
- Phytochemical analysis : PCA
- Food chemistry: X
- The American journal of Chinese medicine
- Pesticide biochemistry and physiology
PANAX NOTOGINSENG SAPONINS
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Frontiers in plant science
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Zhongguo yao li xue bao = Acta pharmacologica Sinica
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
View 14 additional sources
- Acta pharmacologica Sinica
- Journal of ethnopharmacology
- Journal of plant physiology
- Journal of chromatography. A
- Chinese journal of natural medicines
- Food & function
- Yao xue xue bao = Acta pharmaceutica Sinica
- Drug design, development and therapy
- Journal of ginseng research
- Molecules (Basel, Switzerland)
- Annals of vascular surgery
- Plant cell reports
- Phytotherapy research : PTR
- Nan fang yi ke da xue xue bao = Journal of Southern Medical University
RB1
- Chinese medicine
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of ginseng research
- Journal of medicinal food
- Journal of chromatography. A
View 14 additional sources
- Journal of agricultural and food chemistry
- Yao xue xue bao = Acta pharmaceutica Sinica
- Zhongguo yao li xue bao = Acta pharmacologica Sinica
- Talanta
- Journal of separation science
- Hypertension research : official journal of the Japanese Society of Hypertension
- Journal of ethnopharmacology
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Natural product research
- Drug metabolism and disposition: the biological fate of chemicals
- Phytochemical analysis : PCA
- Pesticide biochemistry and physiology
- Microbial biotechnology
RG1
- Journal of fungi (Basel, Switzerland)
- Chinese medicine
- Frontiers in plant science
- Journal of AOAC International
- Gene
View 14 additional sources
- Pharmacological research
- Yao xue xue bao = Acta pharmaceutica Sinica
- Molecules (Basel, Switzerland)
- Chinese journal of biotechnology
- Journal of chromatography. A
- Journal of agricultural and food chemistry
- Zhongguo yao li xue bao = Acta pharmacologica Sinica
- Talanta
- Hypertension research : official journal of the Japanese Society of Hypertension
- Journal of ethnopharmacology
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Drug metabolism and disposition: the biological fate of chemicals
- Microbial biotechnology
Ginsenoside RG1
- PloS one
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Genes
- Frontiers in plant science
View 12 additional sources
- Yao xue xue bao = Acta pharmaceutica Sinica
- Cells
- Acta pharmacologica Sinica
- Biotechnology, biotechnological equipment
- International archives of medicine
- Chinese medicine
- Journal of ginseng research
- Natural products and bioprospecting
- Metabolic engineering
- Journal of ethnopharmacology
- Phytochemical analysis : PCA
- Microbial biotechnology
Ginsenoside rb1
- PloS one
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Genes
- Yao xue xue bao = Acta pharmaceutica Sinica
View 12 additional sources
- Biotechnology, biotechnological equipment
- Journal of the science of food and agriculture
- International archives of medicine
- Chinese medicine
- Journal of ginseng research
- Frontiers in pharmacology
- Folia microbiologica
- Cells
- Journal of ethnopharmacology
- Molecular and cellular probes
- Molecules (Basel, Switzerland)
- Microbial biotechnology
RD
- Journal of fungi (Basel, Switzerland)
- Chinese medicine
- Gene
- Journal of ginseng research
- Journal of medicinal food
View 12 additional sources
- Molecules (Basel, Switzerland)
- Journal of chromatography. A
- Journal of agricultural and food chemistry
- Talanta
- Journal of separation science
- Folia microbiologica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Natural product research
- Drug metabolism and disposition: the biological fate of chemicals
- Frontiers in microbiology
- Microbial biotechnology
Activities
Panax notoginseng has 227 reported activities identified across 113 scientific publications and several other databases. The most consistently reported activities include Neuroprotective, Antioxidant, Antifungal, Antitumor, Cardioprotective.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Neuroprotective | 10 supporting sources | ★★★★★ |
| Antioxidant | 9 supporting sources | ★★★★☆ |
| Antifungal | 4 supporting sources | ★★☆☆☆ |
| Antitumor | 4 supporting sources | ★★☆☆☆ |
| Cardioprotective | 4 supporting sources | ★★☆☆☆ |
| Anticancer | 3 supporting sources | ★★☆☆☆ |
| Antidepressant | 3 supporting sources | ★★☆☆☆ |
| Antidiabetic | 3 supporting sources | ★★☆☆☆ |
| Antihypertensive | 3 supporting sources | ★★☆☆☆ |
| Cytotoxic | 3 supporting sources | ★★☆☆☆ |
Neuroprotective
- Dr. Duke
- Journal of ginseng research
- Heliyon
- European journal of medicinal chemistry
- Frontiers in pharmacology
View 5 additional sources
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Cells
- Oncotarget
- Phytotherapy research : PTR
- Molecules (Basel, Switzerland)
Antioxidant
- Dr. Duke
- Journal of medicinal food
- Journal of ethnopharmacology
- Free radical research
- Plants (Basel, Switzerland)
View 4 additional sources
- Acta pharmacologica Sinica
- Chemistry & biodiversity
- Food chemistry: X
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Antifungal
- Biochemical and biophysical research communications
- The international journal of biochemistry & cell biology
- Planta medica
- Journal of ginseng research
Antitumor
- Dr. Duke
- Journal of agricultural and food chemistry
- Molecules (Basel, Switzerland)
- Journal of ethnopharmacology
Cardioprotective
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- European journal of medicinal chemistry
- Frontiers in pharmacology
- Molecules (Basel, Switzerland)
Anticancer
- Dr. Duke
- European journal of medicinal chemistry
- Current medicinal chemistry
Antidepressant
- Dr. Duke
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Plants (Basel, Switzerland)
Antidiabetic
- Dr. Duke
- Molecules (Basel, Switzerland)
- Journal of ethnopharmacology
Antihypertensive
- Dr. Duke
- Clinical and experimental pharmacology & physiology. Supplement
- Food chemistry: X
Cytotoxic
- Dr. Duke
- Journal of ginseng research
- Natural products and bioprospecting
Medicinal Uses
Panax notoginseng has 119 reported medicinal uses identified across 113 scientific publications and several other databases. The most consistently reported uses include cardiovascular diseases, apoptosis, cancer, inflammation, obesity.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cardiovascular diseases | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 10 sources) | ★★★★★ |
| apoptosis | Biomolecules (and other 9 sources) | ★★★★☆ |
| cancer | Journal of medicinal food (and other 9 sources) | ★★★★☆ |
| inflammation | Frontiers in pharmacology (and other 9 sources) | ★★★★☆ |
| obesity | Journal of the American Heart Association (and other 7 sources) | ★★★★☆ |
| oxidative stress | Oxidative medicine and cellular longevity (and other 7 sources) | ★★★★☆ |
| ischemic stroke | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 6 sources) | ★★★☆☆ |
| atherosclerosis | Chinese medicine (and other 4 sources) | ★★☆☆☆ |
| myocardial infarction | Chinese journal of traumatology = Zhonghua chuang shang za zhi (and other 4 sources) | ★★☆☆☆ |
| platelet aggregation | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 4 sources) | ★★☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Notoginsenoside R1 | Frontiers in pharmacology (and other 4 sources) | ★★☆☆☆ |
| roots | Life sciences (and other 4 sources) | ★★☆☆☆ |
| total saponins | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 4 sources) | ★★☆☆☆ |
| Panax notoginseng saponins | Acta pharmacologica Sinica (and other 3 sources) | ★★☆☆☆ |
| Panax notoginseng saponins (PNS) | Acta pharmacologica Sinica (and other 3 sources) | ★★☆☆☆ |
| Radix Notoginseng | Frontiers in nutrition (and other 2 sources) | ★☆☆☆☆ |
| Rg1 | Zhongguo yao li xue bao = Acta pharmacologica Sinica (and other 2 sources) | ★☆☆☆☆ |
| extracellular vesicles | Journal of nanobiotechnology (and other 2 sources) | ★☆☆☆☆ |
| extracts | Frontiers in pharmacology (and other 2 sources) | ★☆☆☆☆ |
| 4 kinds of acid polysaccharide | BMC cancer (and other 1 sources) | ★☆☆☆☆ |