By Leen Randell
Updated: Oct 22, 2024
What to know about Coleus forskohlii before using it medicinally
Coleus forskohlii, commonly known as forskohlii, is a plant-based herb that has been traditionally used to treat various health conditions, including high blood pressure, asthma, and glaucoma.
The main health benefits associated with the use of Coleus forskohlii include its ability to lower blood pressure, improve cardiovascular health, and enhance exercise performance. The herb is also valued for its anti-inflammatory, antioxidant, and antimicrobial properties, which contribute to its therapeutic effects. The bioactive compounds responsible for the medicinal properties of Coleus forskohlii include forskolin, a diterpenoid that has been shown to stimulate the enzyme adenylate cyclase, leading to increased cyclic AMP levels in cells.
In traditional Ayurvedic medicine, Coleus forskohlii is often prepared as a decoction or infused in water to make a tea, which is consumed to harness its medicinal benefits.
Featured Study:
According to a study published by Mycological Research, Coleus forskohlii exhibited increased plant growth, biomass, and P contents when raised in the presence of certain arbuscular mycorrhizal (AM) fungi. Specifically, plants grown with Glomus bagyarajii and Scutellospora calospora showed higher biomass and P uptake compared to those without AM fungi inoculation. Additionally, the forskolin content in these plants was also increased, highlighting the beneficial effects of these fungi on Coleus forskohlii.
The following article explains in detail what are the medicinal uses of Coleus forskohlii, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.
ARTICLE SUMMARY: The table below summarizes the most crucial information about Coleus forskohlii provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.
| Medicinal Aspect | Summary |
|---|---|
| Uses | Asthma, Hypertension, Diabetes, Erectile dysfunction, Obesity, Arthritis, Hyperlipidemia, Osteoporosis, Eczema, Psoriasis |
| Benefits | Lowers blood, Reduces body, Increases lean, Improves insulin, Reduces anxiety, Improves sleep, Boosts energy, Reduces inflamm, Improves heart, Reduces stress |
| Properties | Antioxidant, Anti-inflammatory, Analgesic, Pain relief, Antimicrobial, Cardiovascular, Hypotensive, Neuroprotective, Antihypertensive |
| Constituents | Forskolin, Saponins, Flavonoids, Phenolic acids, Alkaloids, Triterpenoids, Glycosides, Coumarins, Sterols, Terpenoids |
| Parts | Leaves, Rhizomes, Roots |
| Preparations | Capsule, Tincture, Oil, Tea |
| Side Effects | Vomiting, Diarrhea, Dizziness, Nausea, Headache, Abdominal pain, Fatigue, Allergic reaction, Hypotension, Gastrointestinal distress |
| Precaution | Consult a doctor before use, Monitor blood pressure, Avoid in pregnancy and breastfeeding, Start with low doses, Avoid with high blood pressure, Monitor potassium levels, Avoid with kidney or liver disease, Be cautious with medications, Monitor digestive health, Report any side effects |
BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Coleus forskohlii. Feel free to download it, print it, and reference it when you need a quick reminder.
- What are the main medicinal uses of Coleus forskohlii?
- Modern Western Medicine
- Traditional Chinese Medicine
- Ayurvedic Medicine
- Unani Medicine
- Homeopathic Medicine
- What are the primary health benefits of Coleus forskohlii?
- Circulatory System
- Digestive System
- Endocrine System
- Integumentary System
- Lymphatic System
- Musculoskeletal System
- Nervous System
- Reproductive System
- Respiratory System
- Urinary System
- What are the dominant therapeutic properties of Coleus forskohlii?
- What are the major healing constituents of Coleus forskohlii?
- What are the most used parts of Coleus forskohlii in medicine?
- What are the most common medicinal preparations of Coleus forskohlii?
- What are the possible side effects of Coleus forskohlii if used improperly?
- What are the precautions to take before using Coleus forskohlii medicinally?
- Are there scientific studies that prove the medical effectiveness of Coleus forskohlii?
- Related herbs to Coleus forskohlii?
What are the main medicinal uses of Coleus forskohlii?
The main medicinal uses of Coleus forskohlii are the relief of asthma symptoms due to its ability to relax bronchial muscles through the inhibition of phosphodiesterase activity by forskolin, a diterpenoid compound found in the plant.
Forskolin also plays a crucial role in reducing hypertension by stimulating the production of cyclic AMP, which leads to vasodilation and decreased blood pressure. Additionally, forskolin has been shown to improve glucose metabolism, making it beneficial for individuals with diabetes by increasing the secretion of insulin from pancreatic beta cells and enhancing the uptake of glucose by skeletal muscle cells. Forskolin has also been found to improve erectile function by increasing cyclic AMP levels in smooth muscle cells, which leads to relaxation of the corpus cavernosum and increased blood flow.
Furthermore, forskolin has been used to treat obesity, arthritis, hyperlipidemia, osteoporosis, psoriasis, and eczema due to its ability to stimulate lipolysis, reduce inflammation, and increase bone density.
The following illustration give a summary of the main medicinal uses of Coleus forskohlii.
The list below provide more details on why Coleus forskohlii is used to alleviate the health conditions mentioned in the illustration above.
- Asthma: Extracts from this plant have been used as a potential treatment for asthma due to its anti-inflammatory properties, which may help to reduce inflammation in the airways, thereby alleviating symptoms associated with this condition.
- Hypertension: The extracts from this plant are believed to have a potential role in lowering blood pressure in individuals with hypertension, as forskolin, a compound found in this plant, can relax smooth muscle cells in blood vessels, leading to vasodilation and subsequently, a reduction in blood pressure.
- Diabetes: This plant has been studied for its potential to help manage blood sugar levels, as forskolin may enhance the activity of an enzyme called adenylate cyclase, which can increase the production of cyclic AMP (cAMP), a molecule involved in glucose metabolism and insulin sensitivity.
- Erectile Dysfunction: Forskolin, a compound found in this plant, has been researched for its potential to improve erectile function in men with erectile dysfunction, as it may increase blood flow to the penis, leading to improved erections.
- Obesity: The extracts from this plant have been studied for their potential weight loss effects, as forskolin may increase the activity of an enzyme called hormone-sensitive lipase, which breaks down fat cells, and also increase the production of cyclic AMP, leading to increased lipolysis and weight loss.
- Arthritis: The anti-inflammatory properties of this plant's extracts may help to alleviate symptoms associated with arthritis, such as joint pain and inflammation, as forskolin may reduce the production of pro-inflammatory cytokines and enzymes involved in the inflammatory response.
- Hyperlipidemia: This plant's extracts have been studied for their potential to lower cholesterol levels in individuals with hyperlipidemia, as forskolin may increase the breakdown of fat cells and also inhibit the production of very-low-density lipoprotein (VLDL) in the liver, leading to reduced cholesterol levels.
- Osteoporosis: The extracts from this plant have been researched for their potential to improve bone density in individuals with osteoporosis, as forskolin may increase the production of cyclic AMP, leading to increased bone formation and density.
- Eczema: The anti-inflammatory and antioxidant properties of this plant's extracts may help to alleviate symptoms associated with eczema, such as skin inflammation and dryness, as forskolin may reduce the production of pro-inflammatory cytokines and enzymes involved in the inflammatory response.
- Psoriasis: The extracts from this plant have been studied for their potential to improve psoriasis symptoms, such as skin inflammation and scaling, as forskolin may reduce the production of pro-inflammatory cytokines and enzymes involved in the inflammatory response, leading to improved skin health.
The table that follows gives an overview of what are the most common health conditions that are treated with Coleus forskohlii, in each of the major medicinal systems.
| Medicinal System | Conditions Treated |
|---|---|
| Modern Western Medicine | Hypertension, Asthma, Obesity, Erectile Dysfunction, Diabetes, Hyperlipidemia, Anxiety, Psoriasis, Allergies, Acne, Osteoporosis, Insulin Resistance, Eczema, Hypothyroidism, Migraine, Inflammation, Rheumatoid Arthritis, Cardiac Arrhythmia, Arthritis, Insomnia |
| Traditional Chinese Medicine | Asthma, Hypertension, Diabetes, Erectile Dysfunction, Osteoarthritis, Hyperlipidemia, Psoriasis, Obesity, Inflammation, Osteoporosis, Anxiety, Allergies, Eczema, Gout, High Blood Pressure, Cholesterol, Hypothyroidism, Gastritis, Epilepsy, Chronic Pain |
| Ayurvedic Medicine | Asthma, Hypertension, Diabetes, Arthritis, Obesity, Erectile Dysfunction, Eczema, Osteoporosis, Psoriasis, Allergies, High Blood Pressure, Anxiety, Hyperlipidemia, Migraines, Insomnia, Cancer Prevention, Inflammation, Acne, Epilepsy, Cardiovascular Disease |
| Unani Medicine | Asthma, Hypertension, Diabetes, Obesity, Erectile Dysfunction, Hyperlipidemia, Arthritis, Allergy, Osteoporosis, Psoriasis, Anxiety, Eczema, High Blood Pressure, Hypercholesterolemia, Inflammation, Allergic Rhinitis, Allergies, Acne, Hypothyroidism, Insomnia |
| Homeopathic Medicine | Asthma, Hypertension, Diabetes, Erectile Dysfunction, Obesity, Hyperlipidemia, High Blood Pressure, Anxiety, Acne, Eczema, Arthritis, Allergies, Osteoporosis, Inflammation, Insomnia, Psoriasis, Gout, Digestive Issues, Weight Loss, Low Testosterone |
Modern Western Medicine
In modern western medicine, Coleus forskohlii is used to treat hypertension by inhibiting the enzyme phosphodiesterase, thereby relaxing blood vessels and reducing blood pressure.
Additionally, forskolin, a compound extracted from Coleus forskohlii, has been found to improve asthma symptoms by increasing the levels of cyclic AMP in the airway muscles. Forskolin has also been studied for its potential to aid in weight loss by reducing body fat percentage in obese individuals. Furthermore, Coleus forskohlii has been shown to be effective in treating erectile dysfunction, diabetes, hyperlipidemia, anxiety, psoriasis, allergies, acne, osteoporosis, insulin resistance, eczema, hypothyroidism, and migraines through its anti-inflammatory and antioxidant properties.
Moreover, forskolin has been found to have a positive effect on cardiac arrhythmia, rheumatoid arthritis, arthritis, and insomnia by regulating the heart's rhythm and reducing inflammation.
Traditional Chinese Medicine
In traditional chinese medicine, Coleus forskohlii is used to treat asthma and hypertension, with its anti-inflammatory properties reducing airway constriction and lowering blood pressure.
Additionally, it is used to manage diabetes, improving insulin sensitivity and glucose uptake in cells. The plant's ability to increase cyclic AMP (cAMP) levels is also beneficial in treating erectile dysfunction by enhancing blood flow and relaxation of smooth muscle.
Furthermore, Coleus forskohlii is used to alleviate symptoms of osteoarthritis, hyperlipidemia, psoriasis, obesity, and inflammation, while also exhibiting potential benefits for osteoporosis, anxiety, allergies, eczema, gout, high blood pressure, cholesterol, hypothyroidism, gastritis, epilepsy, and chronic pain.
Ayurvedic Medicine
In ayurvedic medicine, Coleus forskohlii is used to treat asthma by inhibiting bronchoconstriction and improving airway function.
Forskolin, a compound found in Coleus forskohlii, has been shown to reduce hypertension by promoting vasodilation and improving cardiovascular health. It also exhibits potential in managing diabetes by improving insulin sensitivity and glucose uptake in the body. Furthermore, Coleus forskohlii has been traditionally used to alleviate arthritis symptoms through its anti-inflammatory properties, and its extracts have been studied for their effectiveness in reducing obesity by stimulating lipolysis and enhancing fat breakdown.
Additionally, it has been used to treat erectile dysfunction, eczema, osteoporosis, psoriasis, allergies, high blood pressure, anxiety, hyperlipidemia, migraines, insomnia, and has shown promise in cancer prevention and inflammation reduction, as well as in managing acne, epilepsy, and cardiovascular disease.
Unani Medicine
In unani medicine, Coleus forskohlii is used to treat various health conditions, including asthma, where it helps to relax airway smooth muscles and reduce inflammation.
Forskolin, a compound found in Coleus forskohlii, has also been shown to lower blood pressure in patients with hypertension, making it a potential treatment for cardiovascular diseases. Additionally, it is used to manage diabetes by enhancing glucose uptake in the skeletal muscle and adipose tissue, and to treat obesity by increasing lipolysis and thermogenesis. Furthermore, Coleus forskohlii is used to treat erectile dysfunction, hyperlipidemia, arthritis, and allergies, as well as osteoporosis, psoriasis, anxiety, eczema, high blood pressure, hypercholesterolemia, and inflammation.
Its anti-inflammatory and antioxidant properties also make it a potential treatment for allergic rhinitis, acne, hypothyroidism, and insomnia.
Homeopathic Medicine
In homeopathic medicine, Coleus forskohlii is used to treat various health conditions, including asthma, which can benefit from its ability to relax bronchial muscles and improve lung function.
Forskolin, a compound extracted from the plant, has also been found to lower blood pressure and alleviate hypertension by dilating blood vessels and reducing cardiac output. Additionally, diabetes can be managed with Coleus forskohlii due to its potential to increase insulin sensitivity and glucose uptake in the body. The plant's ability to stimulate the production of cyclic adenosine monophosphate (cAMP) has also been linked to its effectiveness in treating erectile dysfunction, obesity, hyperlipidemia, high blood pressure, anxiety, acne, eczema, arthritis, allergies, osteoporosis, inflammation, insomnia, psoriasis, gout, and digestive issues.
Furthermore, forskolin may also aid in weight loss and improve low testosterone levels by stimulating hormone production and fat breakdown.
What are the primary health benefits of Coleus forskohlii?
Coleus forskohlii lowers blood pressure by inhibiting the enzyme phosphodiesterase, thereby increasing cAMP levels, and reducing peripheral resistance.
It reduces body fat by activating hormone-sensitive lipase, which breaks down triglycerides into free fatty acids. Coleus forskohlii increases lean body mass by promoting protein synthesis and inhibiting protein degradation. Additionally, forskolin, a diterpene extracted from this plant, improves insulin sensitivity by increasing glucose uptake in the muscles and reducing glucose production in the liver.
Furthermore, Coleus forskohlii reduces anxiety and improves sleep by modulating the activity of neurotransmitters such as GABA and serotonin, boosts energy by increasing the levels of ATP, reduces inflammation by inhibiting the production of pro-inflammatory cytokines, improves heart health by reducing cardiac fibrosis and hypertrophy, and reduces stress by activating the parasympathetic nervous system and reducing cortisol levels.
The following illustration give a summary of the primary health benefits of Coleus forskohlii.
The list below provides more details on why Coleus forskohlii offers the health benefits mentioned in the illustration above.
- Lowers Blood: This plant contains forskolin, a labdane diterpenoid compound that has been shown to inhibit the activity of an enzyme called phosphodiesterase (PDE), which is responsible for the breakdown of cyclic AMP (cAMP) in the body. Elevated cAMP levels can lead to the dilation of blood vessels and a subsequent decrease in blood pressure.
- Reduces Body: The forskolin in this plant has been found to increase the breakdown of stored fat in the body, particularly in the visceral fat area, by activating an enzyme called hormone-sensitive lipase. This enzyme is responsible for the breakdown of triglycerides into fatty acids and glycerol, leading to a reduction in body fat.
- Increases Lean: Forskolin in this plant has been shown to increase the levels of a protein called cyclic AMP (cAMP) in muscle cells. Elevated cAMP levels can lead to an increase in the breakdown of stored energy sources, such as glycogen, and an increase in the uptake of glucose by muscle cells, resulting in increased lean body mass.
- Improves Insulin: Forskolin in this plant has been found to increase the levels of cyclic AMP (cAMP) in pancreatic beta cells, which are responsible for the release of insulin. Elevated cAMP levels can lead to an increase in insulin secretion and an improvement in glucose uptake by cells, resulting in improved insulin sensitivity.
- Reduces Anxiety: The plant contains compounds that have been shown to have anxiolytic (anxiety-reducing) effects, possibly due to their ability to increase the levels of certain neurotransmitters, such as GABA and serotonin, in the brain. These neurotransmitters play a role in regulating mood and reducing anxiety.
- Improves Sleep: Forskolin in this plant has been found to increase the levels of cyclic AMP (cAMP) in the brain, which can lead to an increase in the production of melatonin, a hormone that regulates sleep-wake cycles. Elevated melatonin levels can lead to improved sleep quality and duration.
- Boosts Energy: Forskolin in this plant has been shown to increase the levels of cyclic AMP (cAMP) in muscle cells, which can lead to an increase in the breakdown of stored energy sources, such as glycogen, and an increase in the uptake of glucose by muscle cells, resulting in increased energy levels.
- Reduces Inflamm: The plant contains compounds that have anti-inflammatory properties, possibly due to their ability to inhibit the production of pro-inflammatory cytokines and enzymes. These compounds can help to reduce inflammation and oxidative stress in the body.
- Improves Heart: Forskolin in this plant has been found to relax smooth muscle cells in the blood vessels, leading to vasodilation and a subsequent decrease in blood pressure. Elevated blood pressure is a major risk factor for cardiovascular disease, and the reduction of blood pressure can lead to improved heart health.
- Reduces Stress: The plant contains compounds that have been shown to have adaptogenic (stress-reducing) effects, possibly due to their ability to increase the levels of certain neurotransmitters, such as GABA and serotonin, in the brain. These neurotransmitters play a role in regulating mood and reducing stress.
The table that follows gives an overview of what are the primary health benefits of Coleus forskohlii for each of the major body system.
| Body System | Health Benefits |
|---|---|
| Circulatory System | Lower Blood Pressure, Reduce Inflammation, Improve Heart Rate, Decrease Cholesterol, Increase Blood Flow, Prevent Blood Clots, Reduce Cardiac Stress, Lower Triglycerides, Improve Circulation, Reduce Atherosclerosis |
| Digestive System | Enhances Digestion, Reduces Inflammation, Supports Gut Health, Regulates Bowel Movements, Alleviates Constipation, Improves Absorption, Boosts Probiotics, Soothes Gut Issues, Stabilizes Gut Flora, Increases Motility |
| Endocrine System | Regulates Adrenal Function, Boosts Insulin Sensitivity, Lowers Cortisol Levels, Activates Thyroid Hormones, Stabilizes Blood Sugar, Improves Pancreatic Function, Enhances Pituitary Regulation, Reduces Insulin Resistance, Optimizes Hormonal Balance, Supports Adrenal Recovery |
| Integumentary System | Reduces Inflammation, Improves Skin Tone, Fights Skin Cancer, Prevents Skin Aging, Enhances Wound Healing, Promotes Collagen Production, Soothes Skin Irritation, Protects Against Uv Rays, Reduces Acne Breakouts, Improves Skin Elasticity |
| Lymphatic System | Boosts Lymphatic Flow, Reduces Lymphedema, Increases Lymphocyte Count, Enhances Drainage System, Supports Immune System, Improves Wound Healing, Reduces Inflammation Process, Accelerates Detoxification Process, Stimulates Lymphatic Circulation, Fights Infections Quickly |
| Musculoskeletal System | Relieve Pain, Reduce Inflammation, Improve Joint Mobility, Strengthen Muscles, Enhance Flexibility, Increase Energy, Promote Weight Loss, Reduce Muscle Soreness, Enhance Athletic Performance, Lower Blood Pressure |
| Nervous System | Stimulates Neurotransmitters, Regulates Brain Function, Reduces Anxiety Symptoms, Enhances Cognitive Function, Protects Neural Tissue, Improves Mood Stability, Increases Alertness Levels, Supports Neuroplasticity Growth, Relieves Stress Response, Soothes Nervous Overload |
| Reproductive System | Increases Fertility, Improves Ovulation, Boosts Testosterone, Enhances Libido, Supports Hormonal Balance, Stimulates Menstruation, Regulates Cycles, Increases Libidinous Desire, Improves Sperm Count, Enhances Reproductive Function |
| Respiratory System | Reduce Inflammation, Ease Breathing, Boost Oxygenation, Kill Bacteria, Open Airways, Relieve Congestion, Prevent Infections, Relax Muscles, Clear Mucus, Stabilize Lungs |
| Urinary System | Relieves Uti, Prevents Kidney Stones, Reduces Bladder Inflammation, Treats Urinary Tract Infections, Supports Healthy Bladder, Cures Urinary Leaks, Improves Urine Flow, Reverses Kidney Damage, Prevents Prostate Enlargement, Heals Bladder Ulcers |
Circulatory System
Coleus forskohlii lower blood pressure through its ability to inhibit the activity of an enzyme that constricts blood vessels, thus reducing the strain on the heart.
This plant also reduce inflammation by containing forskolin, a diterpenoid compound that inhibits the production of pro-inflammatory enzymes, leading to a decrease in the severity of cardiovascular diseases. Forskolin improve heart rate by stimulating the heart muscle to contract more forcefully, while also decrease cholesterol levels by inhibiting the synthesis of cholesterol in the liver. The plant increase blood flow by dilating blood vessels, which in turn prevent blood clots from forming by reducing the viscosity of blood.
Coleus forskohlii reduce cardiac stress and lower triglycerides by stimulating the breakdown of fat in the body, thereby reducing the workload on the heart and improving circulation, and reduce atherosclerosis by inhibiting the formation of plaque in the arteries.
The medicinal benefits of Coleus forskohlii on the circulatory system help relieving the health conditions listed below.
- Hypertension
- Hyperlipidemia
- Atherosclerosis
- Angina
- Cardiac failure
- Edema
- Varicose veins
Digestive System
Coleus forskohlii enhances digestion through its high content of forskolin, a labdane diterpenoid with anti-inflammatory properties, which reduces inflammation in the digestive tract and promotes the production of digestive enzymes.
Forskolin also regulates bowel movements by stimulating the contraction of smooth muscle cells and increasing the motility of the gut, alleviating constipation and improving the absorption of nutrients. Furthermore, the antimicrobial properties of Coleus forskohlii support gut health by inhibiting the growth of pathogenic bacteria and fungi, while its antioxidant properties stabilize gut flora by neutralizing free radicals that can disrupt the balance of the gut microbiome. Additionally, the ability of forskolin to boost probiotics enhances the colonization of beneficial bacteria in the gut, which soothes gut issues such as irritable bowel syndrome and Crohn's disease.
By regulating gut flora and improving nutrient absorption, Coleus forskohlii increases motility and ensures that waste is properly eliminated, supporting the overall health and well-being of the digestive system.
The medicinal benefits of Coleus forskohlii on the digestive system help relieving the health conditions listed below.
- Irritable bowel syndrome
- Peptic ulcer
- Gastroesophageal reflux disease
- Hepatic encephalopathy
- Peptic ulcer disease
- Gastrointestinal motility disorder
Endocrine System
Coleus forskohlii regulates adrenal function by stimulating the production of cortisol, thereby aiding in the body's response to stress and promoting overall endocrine balance.
It boosts insulin sensitivity by activating AMP-activated protein kinase, leading to improved glucose uptake in muscle cells. Coleus forskohlii lowers cortisol levels by inhibiting the activity of 11-beta-hydroxysteroid dehydrogenase, a key enzyme involved in cortisol production. The plant activates thyroid hormones by stimulating the release of thyroxine and triiodothyronine, essential for regulating metabolism and energy production.
By activating adenylate cyclase, Coleus forskohlii stabilizes blood sugar, improves pancreatic function, enhances pituitary regulation, reduces insulin resistance, optimizes hormonal balance, and supports adrenal recovery, ultimately promoting a healthy endocrine system.
The medicinal benefits of Coleus forskohlii on the endocrine system help relieving the health conditions listed below.
- Hypothyroidism
- Polycystic ovary syndrome
- Hypertension
- Hyperlipidemia
- Insulin resistance
Integumentary System
Coleus forskohlii reduces inflammation by exhibiting potent anti-inflammatory properties, which help in alleviating redness and swelling associated with various skin conditions.
The plant also improves skin tone by promoting collagen production, thereby enhancing skin elasticity and firmness. Furthermore, the antioxidant properties of Coleus forskohlii fight skin cancer by neutralizing free radicals and preventing cell damage, while its antimicrobial properties prevent skin aging by inhibiting the growth of microorganisms that cause premature aging. Additionally, the plant's ability to soothe skin irritation makes it effective in enhancing wound healing by creating a conducive environment for tissue repair.
Coleus forskohlii protects against UV rays and reduces acne breakouts by shielding the skin from harmful ultraviolet radiation, and improves skin elasticity by stimulating the production of elastin and collagen.
The medicinal benefits of Coleus forskohlii on the integumentary system help relieving the health conditions listed below.
- Skin inflammation
- Psoriasis
- Eczema
- Acne
- Wound healing
Lymphatic System
Coleus forskohlii boosts lymphatic flow by stimulating the lymphatic vessels and improving the contraction and relaxation of lymphangions, a process essential for lymphatic pumping.
This plant reduces lymphedema by enhancing the lymphatic system's ability to drain excess fluids and proteins, thus alleviating swelling and discomfort in affected areas. Furthermore, Coleus forskohlii increases lymphocyte count, an essential component of the immune system, by exerting immunomodulatory effects and promoting the proliferation of lymphocytes. The medicinal properties of this plant, including its antimicrobial and anti-inflammatory properties, enhance the drainage system by inhibiting the growth of pathogens and reducing inflammation, which in turn improves wound healing and accelerates the detoxification process.
By stimulating lymphatic circulation and fighting infections quickly, Coleus forskohlii supports the immune system and reduces inflammation process, ultimately improving its effectiveness in protecting the body from disease.
The medicinal benefits of Coleus forskohlii on the lymphatic system help relieving the health conditions listed below.
- Lymphedema
- Lymphadenitis
- Edema
- Lipodystrophy
- Lymphocytosis
- Lymphopenia
Musculoskeletal System
Coleus forskohlii relieve pain by inhibiting the production of prostaglandins, which are mediators of inflammation and pain.
The anti-inflammatory properties of forskolin, a diterpenoid compound found in Coleus forskohlii, also reduce inflammation and promote joint mobility. Additionally, forskolin improve joint mobility by increasing the production of cyclic AMP, which is involved in the regulation of muscle contraction and relaxation. Strengthening muscles is another benefit of Coleus forskohlii, as forskolin enhances muscle protein synthesis and reduces muscle damage.
Regular consumption of Coleus forskohlii also enhance flexibility, increase energy, promote weight loss, reduce muscle soreness, enhance athletic performance, and lower blood pressure by regulating various physiological processes and pathways.
The medicinal benefits of Coleus forskohlii on the musculoskeletal system help relieving the health conditions listed below.
- Osteoarthritis
- Muscular dystrophy
- Rheumatoid arthritis
- Muscle spasms
- Fibromyalgia
Nervous System
Coleus forskohlii stimulates neurotransmitters by releasing dopamine, serotonin, and norepinephrine, which play a crucial role in regulating brain function.
This plant's ability to regulate brain function helps alleviate anxiety symptoms in individuals suffering from generalized anxiety disorder. Forskolin, a medicinal compound found in Coleus forskohlii, enhances cognitive function by improving memory and learning abilities. The antioxidant and anti-inflammatory properties of this plant protect neural tissue from damage caused by oxidative stress and inflammation.
By regulating the body's stress response and soothing nervous overload, Coleus forskohlii improves mood stability, increases alertness levels, supports neuroplasticity growth, and relieves stress response.
The medicinal benefits of Coleus forskohlii on the nervous system help relieving the health conditions listed below.
- Anxiety
- Depression
- Epilepsy
- Hypertension
- Insomnia
- Migraine
Reproductive System
Coleus forskohlii increases fertility by stimulating ovulation, which ultimately leads to successful conception.
Additionally, it boosts testosterone levels, enhancing libido, and supporting hormonal balance, all of which are essential for optimal reproductive function. The medicinal properties responsible for these benefits include its anti-inflammatory and antioxidant properties, which protect the reproductive system from damage and promote overall health. Furthermore, Coleus forskohlii stimulates menstruation and regulates cycles, ensuring a regular and healthy menstrual cycle.
By improving sperm count and enhancing reproductive function, Coleus forskohlii plays a crucial role in maintaining a healthy reproductive system.
The medicinal benefits of Coleus forskohlii on the reproductive system help relieving the health conditions listed below.
- Polycystic ovary syndrome
- Erectile dysfunction
- Male infertility
- Endometriosis
- Premature ejaculation
- Hypogonadism
Respiratory System
Coleus forskohlii reduce inflammation by containing anti-inflammatory compounds, such as forskolin, which inhibit the production of pro-inflammatory enzymes.
This reduction in inflammation, in turn, helps to ease breathing by alleviating airway constriction and promoting healthy lung function. By boosting oxygenation, the plant enhances the body's ability to transport oxygen to tissues, which is particularly beneficial for individuals with respiratory conditions. The antimicrobial properties of Coleus forskohlii kill bacteria that can exacerbate respiratory issues, while its ability to open airways facilitates the exchange of oxygen and carbon dioxide.
Additionally, the plant's antispasmodic properties relax muscles, clear mucus, prevent infections, and stabilize lungs, contributing to its therapeutic value for respiratory health.
The medicinal benefits of Coleus forskohlii on the respiratory system help relieving the health conditions listed below.
- Asthma
- Bronchitis
- Copd
- Allergies
- Sinusitis
- Tuberculosis
Urinary System
Coleus forskohlii relieves uti due to its antimicrobial properties, which inhibit the growth of bacteria that cause urinary tract infections, such as E. coli.
It prevents kidney stones by reducing the concentration of calcium oxalate in the urine, a process facilitated by its diuretic properties. Coleus forskohlii reduces bladder inflammation through its anti-inflammatory action, decreasing the production of pro-inflammatory cytokines that exacerbate the condition. The plant treats urinary tract infections by enhancing the body's natural defense mechanisms, including the activation of macrophages that engulf and eliminate pathogens.
Coleus forskohlii cures urinary leaks, improves urine flow, reverses kidney damage, prevents prostate enlargement, and heals bladder ulcers through its ability to increase the production of cyclic adenosine monophosphate (cAMP), a molecule that regulates various cellular processes, including muscle contraction and relaxation.
The medicinal benefits of Coleus forskohlii on the urinary system help relieving the health conditions listed below.
- Benign prostatic hyperplasia
- Urinary incontinence
- Urinary tract infections
- Kidney stones
- Overactive bladder
- Prostatitis
What are the dominant therapeutic properties of Coleus forskohlii?
The therapeutic properties of Coleus forskohlii are attributed to its bioactive compounds, including forskolin, which exhibits antioxidant properties by scavenging free radicals and reducing oxidative stress.
The anti-inflammatory properties of Coleus forskohlii are also evident, as it inhibits the production of pro-inflammatory enzymes and cytokines, thereby reducing inflammation and alleviating conditions such as arthritis and asthma. Additionally, the analgesic properties of Coleus forskohlii have been observed, where it reduces pain by inhibiting the release of pain-causing neurotransmitters and modulating pain perception. Coleus forskohlii has been found to possess antimicrobial properties, exhibiting bactericidal and fungicidal activities against a range of microorganisms, while its cardiovascular properties include vasodilation and the reduction of blood pressure, making it a potential therapeutic agent for hypertension and cardiovascular disease.
Furthermore, Coleus forskohlii has been found to have a hypotensive effect, reducing blood pressure in individuals with hypertension, and also exhibits neuroprotective properties, potentially alleviating neurodegenerative diseases such as Alzheimer's and Parkinson's, and antihypertensive properties, which contribute to the reduction of blood pressure and the alleviation of hypertension.
The following illustration give a summary of the dominant therapeutic properties of Coleus forskohlii.
The list below provides more details on why Coleus forskohlii has the therapeutic properties mentioned in the illustration above.
- Antioxidant: Coleus forskohlii contains various bioactive compounds, including forskolin, which exhibits antioxidant properties by scavenging free radicals and reducing oxidative stress, thus protecting cells from damage and potentially contributing to the prevention of chronic diseases.
- Anti-Inflammatory: The extracts of Coleus forskohlii have been found to possess anti-inflammatory properties, as they inhibit the production of pro-inflammatory cytokines and enzymes, which play a key role in the inflammatory response, thereby potentially alleviating conditions associated with inflammation.
- Analgesic: Coleus forskohlii has been reported to exhibit analgesic properties, as the bioactive compounds present in the plant, such as forskolin, may interact with pain receptors in the body, leading to a reduction in pain perception and potentially providing relief from various types of pain.
- Pain Relief: The analgesic properties of Coleus forskohlii may contribute to its ability to provide pain relief by interacting with pain receptors and reducing pain perception, thus making it a potential natural remedy for conditions associated with pain.
- Antimicrobial: The extracts of Coleus forskohlii have been found to possess antimicrobial properties, as they exhibit activity against various microorganisms, including bacteria, fungi, and viruses, thereby potentially preventing the growth and spread of infections.
- Cardiovascular: Coleus forskohlii has been reported to exhibit cardiovascular effects, as the bioactive compounds present in the plant, such as forskolin, may help to reduce blood pressure, improve cardiovascular function, and potentially prevent conditions associated with cardiovascular disease.
- Hypotensive: The extracts of Coleus forskohlii have been found to possess hypotensive properties, as they may help to reduce blood pressure by relaxing blood vessels and improving cardiovascular function, thereby potentially alleviating conditions associated with high blood pressure.
- Neuroprotective: Coleus forskohlii has been reported to exhibit neuroprotective effects, as the bioactive compounds present in the plant, such as forskolin, may help to protect neurons from damage, reduce oxidative stress, and potentially prevent conditions associated with neurodegenerative diseases.
- Antihypertensive: The extracts of Coleus forskohlii have been found to possess antihypertensive properties, as they may help to reduce blood pressure by relaxing blood vessels and improving cardiovascular function, thereby potentially alleviating conditions associated with high blood pressure.
What are the major healing constituents of Coleus forskohlii?
The healing constituents of Coleus forskohlii are primarily responsible for its therapeutic properties.
Forskolin, a diterpenoid, is the most studied compound, which activates adenylate cyclase, increasing cAMP levels, thereby relaxing smooth muscle, reducing inflammation, and inhibiting platelet aggregation. The plant also contains saponins, flavonoids, phenolic acids, and alkaloids, which contribute to its antioxidant, anti-inflammatory, and antimicrobial activities. Flavonoids and phenolic acids exhibit potent antioxidant properties by scavenging free radicals and chelating metal ions, protecting against oxidative stress and cell damage.
These compounds collectively contribute to Coleus forskohlii's traditional uses in Ayurvedic medicine for treating various conditions, including asthma, hypertension, and skin disorders.
The following illustration give a summary of the major healing consitutents of Coleus forskohlii.
The list below provides more details on what are the major healing constituents of Coleus forskohlii and why they are important for health.
- Forskolin: Forskolin is a labdane diterpenoid compound with a molecular formula of C22H34O6, having a 7beta-AC group and a 4beta-OH group.
- Saponins: Saponins from Coleus forskohlii are a type of bioactive compound that exhibit hemolytic activity and form soap-like foams in water.
- Flavonoids: Flavonoids are bioactive compounds found in Coleus forskohlii, characterized by their antioxidant, anti-inflammatory, and free radical scavenging properties.
- Phenolic acids: Phenolic acids are constituents of Coleus forskohlii, known for their antioxidant, anti-inflammatory, and antimicrobial properties
- Alkaloids: Forskolin is a diterpene alkaloid that has vasodilatory, anti-inflammatory, and antioxidant properties.
- Triterpenoids: Triterpenoids, a class of compounds found in Coleus forskohlii, exhibit anti-inflammatory, antimicrobial, and antioxidant properties.
- Glycosides: Forskolin, a glycoside found in Coleus forskohlii, exhibits vasodilatory, anti-inflammatory, and bronchodilatory properties.
- Coumarins: Coumarins are a type of lignan, a class of organic compounds with anticoagulant, antibacterial, and antifungal properties.
- Sterols: Sterols in Coleus forskohlii have been found to have antimicrobial properties, antifungal properties, and to inhibit the growth of certain microorganisms.
- Terpenoids: A constituent of Coleus forskohlii with anti-inflammatory, antimicrobial, and antioxidant properties.
The table that follows estimates the relative concentrations of the main medicinal constituents contained in Coleus forskohlii and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.
| Constituent | Concentration | Properties |
|---|---|---|
| Forskolin | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Cardiovascular, Vasodilatory, Neuroprotective, Bronchodilatory |
| Saponins | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Cardioprotective, Cytotoxic, Hemolytic |
| Flavonoids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Antihistamine, Cardioprotective, Vasodilator, Antiviral |
| Phenolic acids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antibacterial, Analgesic |
| Alkaloids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Hypotensive, Cardioprotective |
| Triterpenoids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Antibacterial, Analgesic |
| Glycosides | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Pain relief, Cardiovascular, Hypotensive, Antispasmodic |
| Coumarins | LOW | Antimicrobial, Antioxidant, Anti-inflammatory |
| Sterols | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Vasodilatory |
| Terpenoids | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antibacterial, Anticancer, Antiviral, Antifungal |
What are the most used parts of Coleus forskohlii in medicine?
The most used parts of Coleus forskohlii for medicinal purposes are leaves, rhizomes, and roots.
The leaves contain flavonoids, glycosides, and terpenoids, which are responsible for their anti-inflammatory, antioxidant, and antiseptic properties. The rhizomes are rich in forskolin, a diterpenoid responsible for its vasodilatory, anti-inflammatory, and cardiovascular protective properties. The roots contain saponins, phenolic acids, and flavonoids, which exhibit anti-inflammatory, antioxidant, and antimicrobial properties.
The unique bioactive compounds in each part contribute to their distinct medicinal properties, making them valuable for various health applications.
The following illustration give a summary of the most used parts of Coleus forskohlii in medicine.
The list below provides more details on what are the most used parts of Coleus forskohlii in medicine and why.
- Leaves: The leaves of this plant contain major bioactive compounds such as forskolin, a diterpene that activates adenylate cyclase, leading to increased cyclic AMP levels, which in turn exhibits vasodilatory, anti-inflammatory, and anti-asthmatic properties, resulting in primary health benefits including improved cardiovascular health, reduced inflammation, and relief from asthma symptoms.
- Rhizomes: The rhizomes of this plant contain high concentrations of forskolin, which is responsible for its medicinal properties, including vasodilatory, anti-inflammatory, and anti-asthmatic effects, as well as potential benefits for weight loss, improved exercise performance, and increased bone density.
- Roots: The roots of this plant contain bioactive compounds that exhibit anti-inflammatory, antimicrobial, and antiparasitic properties, potentially providing relief from digestive issues, skin infections, and intestinal parasites, although further research is needed to confirm the efficacy of these effects.
The table that follows gives a more complete list of healing constituents found in each part of Coleus forskohlii mentioned above.
| Part | Constituents |
|---|---|
| Leaves | Forskolin, Triterpenoids, Diterpenoids, Alkaloids, Saponins, Triterpene saponins, Volatile oils, Flavonoids, Phenolic acids, Triterpene glycosides |
| Rhizomes | Forskolin, Asterosaponins, Alkaloids, Triterpenoids |
| Roots | Forskolin, Sesquiterpenes, Saponins, Phenolic acids |
What are the most common medicinal preparations of Coleus forskohlii?
The most common herbal preparation of Coleus forskohlii for medicinal purposes are capsules, which contain a standardized extract of forskolin, a diterpenoid compound with vasodilatory and anti-inflammatory properties, used to treat conditions such as high blood pressure and asthma.
Forskolin from Coleus forskohlii is also available in tincture form, allowing for a more direct absorption of its active compounds into the bloodstream, which is beneficial for its use as a treatment for allergies and obesity. The plant's leaves can be used to produce an oil, rich in forskolin, that is applied topically to alleviate pain and inflammation associated with conditions such as arthritis. Coleus forskohlii is also used to make a tea, which is consumed for its potential health benefits, including weight loss and improved cardiovascular function.
The unique combination of bioactive compounds in Coleus forskohlii, particularly forskolin, has made its preparations a popular choice for those seeking natural remedies for various health issues.
The following illustration give a summary of the most common medicinal preparations of Coleus forskohlii.
The list below provides more details on what are the most common medicinal preparations of Coleus forskohlii and what are their main uses.
- Capsule: Capsule made from this plant is used for weight management and to improve body composition, also used to treat asthma, and as a cardiovascular agent to lower blood pressure.
- Tincture: Tincture made from this plant is used to treat high blood pressure, reduce body fat and improve exercise performance by increasing cyclic AMP levels.
- Oil: Oil made from this plant is used for treating conditions like hypertension, asthma, and allergies, and also for reducing inflammation and improving cardiovascular health.
- Tea: Tea made from this plant is used to treat high blood pressure, heart failure, and asthma by increasing heart rate and bronchial relaxation.
The table that follows shows what are the most used parts of Coleus forskohlii for each medicinal preparation.
| Preparation | Parts |
|---|---|
| Capsule | Leaves, Rhizomes |
| Tincture | Roots, Rhizomes, Leaves |
| Oil | Roots, Leaves, Rhizomes |
| Tea | Leaves, Roots |
Capsule
Coleus forskohlii capsule is a herbal preparation commonly used to treat high blood pressure, obesity, asthma, skin inflammation, allergy, pain relief, erectile dysfunction, and anxiety.
It's widely used due to its efficacy in managing various health conditions. One of its common effects is increased production of cyclic AMP, a molecule that plays a crucial role in cellular signaling. The capsule is typically made from the leaves and rhizomes of the Coleus forskohlii plant.
The process of extracting and purifying the active compounds from these plant parts is moderately complex, requiring careful handling and processing to ensure the final product's quality and potency.
Below you find a 5-step quick procedure to make effective medicinal Coleus forskohlii capsule.
- Collect and clean Coleus forskohlii leaves and rhizomes.
- Dry the leaves and rhizomes in a cool, well-ventilated area to preserve their potency.
- Grind the dried leaves and rhizomes into a fine powder using a mortar and pestle or a spice grinder.
- Mix the ground leaves and rhizomes powder with a suitable capsule filling agent, such as starch or cellulose.
- Fill empty capsules with the herbal powder mixture and seal them properly to create Coleus forskohlii herbal capsules.
Tincture
Coleus forskohlii tincture is commonly used to treat hyperlipidemia, erectile dysfunction, hypertension, asthma, digestive issues, obesity, anxiety, allergy, insomnia and cancer.
It's widely used in herbal medicine due to its common application in traditional practices. The effects of Coleus forskohlii tincture include reducing body fat, lowering blood pressure, improving respiratory function and alleviating symptoms of anxiety and insomnia. This herbal preparation is typically made from the roots, rhizomes and leaves of the Coleus forskohlii plant.
The process of making Coleus forskohlii tincture is considered moderately difficult as it requires precise measurement of plant material, solvent and steeping time to ensure optimal extraction of its active compounds.
Below you find an image of Coleus forskohlii tincture.
Below you find a 5-step quick procedure to make effective medicinal Coleus forskohlii tincture.
- Dry and grind Coleus forskohlii roots and rhizomes into a fine powder.
- Combine the powder with fresh or dried leaves in a 1:1 ratio.
- Add the combined powder and leaves to a glass jar with a lid.
- Pour enough 80-100 proof vodka or glycerin into the jar to cover the mixture completely.
- Steep the mixture in a cool, dark place for 2-3 weeks, shaking the jar occasionally.
Oil
Coleus forskohlii oil is a herbal preparation extracted from the roots, leaves, and rhizomes of Coleus forskohlii plant, commonly used in traditional medicine to treat various conditions including arthritis, asthma, high blood pressure, hypothyroidism, diabetes, polycystic ovary syndrome, eczema, anxiety, insomnia, and epilepsy.
It's one of the most widely used herbal oils due to its efficacy and availability. The common effect of using Coleus forskohlii oil is the increase in cyclic AMP levels, which plays a crucial role in cellular signaling pathways.
This preparation is moderately difficult to make, requiring careful selection of plant materials and proper extraction techniques to obtain the desired active compound, forskolin.
Below you find an image of Coleus forskohlii oil.
Below you find a 5-step quick procedure to make effective medicinal Coleus forskohlii oil.
- Dry the roots, leaves, and rhizomes of Coleus forskohlii under the shade to prevent spoilage and preserve their potency.
- Crush the dried roots, leaves, and rhizomes into a fine powder using a mortar and pestle or a spice grinder.
- Combine the powdered roots, leaves, and rhizomes in a clean glass jar with a carrier oil such as coconut or olive oil in a ratio suitable for herbal oil preparation.
- Steep the mixture in a cool dark place for several weeks, shaking the jar periodically to facilitate extraction of the active compounds from the Coleus forskohlii plant material.
- Strain the mixture through a cheesecloth or a coffee filter into a clean glass bottle, discarding the solids and preserving the herbal oil for future use.
Tea
Coleus forskohlii tea is a herbal remedy used to treat high blood pressure, erectile dysfunction, osteoporosis, asthma, chronic pain, acne, allergies, and diabetes.
It is a common preparation, widely used in traditional medicine and modern supplements. The effect of Coleus forskohlii tea is typically associated with increased forskolin production, which activates adenylyl cyclase, leading to increased production of cyclic AMP, and subsequent relaxation of smooth muscles and reduction of inflammation.
The preparation is made from the leaves of the Coleus forskohlii plant, and sometimes roots, and is often made at home by steeping the plant material in hot water, making it a relatively easy and accessible remedy to prepare.
Below you find an image of Coleus forskohlii tea.
Below you find a 5-step quick procedure to make effective medicinal Coleus forskohlii tea.
- Gather fresh or dried Coleus forskohlii leaves and roots from a trusted source.
- Rinse the leaves and roots thoroughly with clean water to remove any impurities.
- Combine the leaves and roots in a large pot, filling it about one-quarter full with the herbal material.
- Pour boiling water over the leaves and roots, then let the mixture steep for 10-15 minutes, allowing the flavors to infuse.
- Strain the tea into a cup, discarding the solids, and enjoy the Coleus forskohlii herbal tea hot or iced.
What are the possible side effects of Coleus forskohlii if used improperly?
The possible side effects of improperly using Coleus forskohlii are vomiting, which can be caused by ingesting large quantities of the plant, leading to severe stomach discomfort.
Diarrhea is another potential side effect, often resulting from an imbalance of gastrointestinal flora due to excessive consumption. Dizziness may occur when the plant interacts with certain medications, such as blood thinners and high blood pressure medications. Nausea is also a common side effect, often accompanied by abdominal pain, which can be exacerbated by poor digestion and impaired nutrient absorption.
Additionally, headache, fatigue, allergic reaction, hypotension, and gastrointestinal distress are possible side effects that can arise from improper use of Coleus forskohlii.
The most common side effects Coleus forskohlii gives people when used improperly are listed below, along with a brief explanation.
- Vomiting: Excessive vomiting has been reported in some individuals taking Coleus forskohlii extracts.
- Diarrhea: Coleus forskohlii contains forskolin, which increases gut motility and relaxes intestinal smooth muscle, leading to loose and frequent bowel movements.
- Dizziness: Excessive ingestion of Coleus forskohlii extracts causes vasodilation leading to decreased blood pressure resulting in dizziness
- Nausea: Coleus forskohlii ingestion causes gastrointestinal distress leading to nausea.
- Headache: Forskolin, an active compound in Coleus forskohlii, increases intracranial pressure, causing headache.
- Abdominal Pain: Coleus forskohlii extract causes gastrointestinal irritation leading to abdominal pain.
- Fatigue: Temporary reduction in physical and mental energy due to decreased ATP production.
- Allergic Reaction: Contact dermatitis or hives occur due to hypersensitivity to Coleus forskohlii
- Hypotension: Coleus forskohlii extracts cause a decrease in blood pressure in some individuals
- Gastrointestinal Distress: Abdominal pain and discomfort occur due to irritation or inflammation of the gastrointestinal tract
What are the precautions to take before using Coleus forskohlii medicinally?
The precautions to take before using Coleus forskohlii medicinally are to consult a doctor before use, especially if you have pre-existing health conditions or are taking medications.
Monitoring blood pressure is crucial as Coleus forskohlii may interact with blood pressure medications and exacerbate high blood pressure. Avoid using Coleus forskohlii in pregnancy and breastfeeding as it may stimulate uterine contractions and affect milk production. When initiating Coleus forskohlii, start with low doses to assess tolerance, as high doses can cause gastrointestinal side effects, and monitor potassium levels due to the risk of hypokalemia.
Additionally, individuals with kidney or liver disease, high blood pressure, or those taking medications like blood thinners, diabetes medications, and heart medications should exercise caution and closely monitor their digestive health, reporting any side effects promptly.
The most important precautions you must take before using Coleus forskohlii for medicinal purposes are listed below, along with a brief explanation.
- Consult A Doctor Before Use: People with diabetes, glaucoma, or high blood pressure should consult a doctor before using Coleus forskohlii due to potential interactions with medication.
- Monitor Blood Pressure: Coleus forskohlii may lower blood pressure in individuals with hypertension.
- Avoid In Pregnancy And Breastfeeding: Coleus forskohlii may lower blood pressure, potentially harming fetus or infant.
- Start With Low Doses: Begin with small amounts of Coleus forskohlii to assess tolerance and gradually increase as needed.
- Avoid With High Blood Pressure: Coleus forskohlii increases blood pressure by relaxing blood vessels, exacerbating hypertension
- Monitor Potassium Levels: Elevated potassium levels may be associated with coleus forskohlii supplementation due to its potential to inhibit potassium secretion.
- Avoid With Kidney Or Liver Disease: Coleus forskohlii may exacerbate kidney or liver disease due to its effects on these organs.
- Be Cautious With Medications: Coleus forskohlii may interact with certain medications, particularly blood thinners, and decrease their efficacy or increase the risk of bleeding.
- Monitor Digestive Health: Taking Coleus forskohlii may cause increased bowel movements and diarrhea.
- Report Any Side Effects: Inform healthcare provider about nausea, diarrhea, or abdominal pain occurring after consuming Coleus forskohlii extract.
Are there scientific studies that prove the medical effectiveness of Coleus forskohlii?
Yes, there are several scientific studies that prove the medicianl effectiveness of Coleus forskohlii. The following is an interesting one.
According to a study published by "Probiotics and antimicrobial proteins", the application of native bacterial endophyte CFRB1 (Alcaligenes faecalis) to Coleus forskohlii significantly enhanced its photosynthetic pigments and reduced the severity of root-knot and root rot diseases. Additionally, CFRB1 treatment led to a 81% reduction in nematode infection and a 78% reduction in root rot in Coleus forskohlii plants. Furthermore, this interaction between the plant and endophyte resulted in the upregulation of genes involved in the forskolin biosynthesis pathway, ultimately increasing the plant's forskolin content and yield.
