10 Possible Side Effects Of Andrographis Paniculata (King Of Bitters)

This article explains in details the 10 most common side effects of Andrographis paniculata if used imporperly.

1. Lowers blood sugar

Andrographis paniculata causes allergic reactions in some individuals.

This is due to its high content of andrografin, a compound that can stimulate the immune system, leading to an overactive response in people with sensitive skin or allergies.

The allergic reaction may manifest as hives, itching, redness, swelling, or even difficulty breathing in severe cases.

2. Lowers blood sugar

Andrographis paniculata triggers stomach upset due to its bitter and warming properties that can irritate the digestive system.

The herb's ability to stimulate digestion and increase gut motility can cause discomfort, bloating, and nausea in some individuals.

Additionally, Andrographis paniculata contains alkaloids that may also contribute to stomach upset by altering the natural balance of gut bacteria and increasing inflammation in the digestive tract.

3. Lowers blood sugar

Andrographis paniculata produces nausea due to its bitter and pungent properties.

The herb contains andrographolide, a compound that can cause gastrointestinal irritation, leading to symptoms such as nausea, vomiting, and stomach discomfort.

As the body adjusts to the presence of this potent herb, some individuals may experience mild nausea, which is typically a temporary and reversible side effect.

4. Lowers blood sugar

Andrographis paniculata increases heart rate due to its ability to stimulate the autonomic nervous system.

This herb's bioactive compounds, particularly andrographolide, can cause a direct effect on the cardiovascular system, leading to increased cardiac output and heart rate.

Additionally, Andrographis paniculata has been shown to enhance sympathetic nerve activity, which further contributes to the increase in heart rate.

5. Lowers blood sugar

Andrographis paniculata raises blood pressure due to its ability to stimulate the cardiovascular system and increase heart rate.

This is attributed to the presence of bioactive compounds such as flavonoids and alkaloids that have a direct effect on the body's vascular tone, causing vessels to constrict and blood pressure to rise.

As a result, individuals may experience increased systolic pressure, contributing to an elevated risk for cardiovascular-related complications.

6. Lowers blood sugar

Andrographis paniculata induces diarrhea due to its ability to stimulate digestive activity and increase bowel movements.

The plant's bitter compounds, such as andrographolide, can irritate the stomach lining, leading to increased motility and frequency of bowel movements. This side effect is often accompanied by abdominal cramps, bloating, and nausea.

The severity of diarrhea may vary depending on individual tolerance to Andrographis paniculata's bioactive compounds.

7. Lowers blood sugar

Andrographis paniculata worsens bleeding disorders due to its ability to inhibit platelet aggregation and increase prothrombin time.

This herb has been shown to prolong clotting times, which can exacerbate bleeding tendencies in individuals with pre-existing coagulation disorders. Furthermore, Andrographis paniculata's effect on blood vessel constriction may also contribute to the worsening of bleeding disorders.

As a result, caution is advised when using this herb in individuals with bleeding disorders.

8. Lowers blood sugar

Andrographis paniculata enhances sedation due to its ability to increase GABA levels in the brain.

GABA is a neurotransmitter that promotes relaxation and reduces anxiety. As Andrographis paniculata interacts with the body's natural chemistry, it can cause drowsiness or sleepiness, potentially leading to enhanced sedation.

This side effect may be more pronounced when taking high doses or combining the herb with other sedative substances.

9. Lowers blood sugar

Andrographis paniculata decreases appetite.

This side effect is likely due to the herb's ability to increase digestive heat and stimulate the release of stomach acids, which can lead to feelings of nausea and decreased hunger. Additionally, Andrographis' bitter taste may also contribute to a decrease in appetite, as the bitterness can suppress the appetite-stimulating hormones in the body.

As a result, individuals taking Andrographis paniculata may experience a temporary reduction in their desire for food.

10. Lowers blood sugar

Andrographis paniculata affects liver function.

The compound andrographolide present in Andrographis paniculata may cause liver damage or inflammation due to its ability to increase the production of certain enzymes that help break down toxins.

Additionally, Andrographis paniculata may interfere with liver detoxification processes, leading to an accumulation of toxic compounds and potential harm to liver cells.