By Leen Randell
Updated: Oct 20, 2024
What to know about Andrographis paniculata before using it medicinally
Andrographis paniculata, commonly known as king of bitters, is a medicinal herb widely used to treat various health conditions, including fever, respiratory infections, and inflammatory diseases such as arthritis and asthma.
Its main health benefits include anti-inflammatory, antioxidant, and immunomodulatory effects, which contribute to its therapeutic properties of reducing inflammation, fighting oxidative stress, and modulating the immune system. The herb's therapeutic properties are attributed to its main bioactive compounds, including andrographolide, neoandrographolide, and 14-deoxyandrographolide, which have been shown to exhibit anti-inflammatory, antioxidant, and antimicrobial activities. In traditional herbal medicine, Andrographis paniculata is commonly prepared as a decoction or a tea by infusing the dried leaves in hot water, which is believed to enhance the bioavailability of its active compounds.
This herbal preparation has been used for centuries in various cultures to treat a range of health conditions, and its medicinal properties have been extensively studied and validated by modern scientific research.
Featured Study:
According to a study published by "Cureus", Andrographis paniculata has been found to possess antibacterial, antioxidative, antidiabetic, anti-inflammatory, and anti-cancer activities, making it a versatile medicinal agent. It has been traditionally used to treat a wide range of diseases, including those affecting the upper gastrointestinal tract, upper respiratory tract, fever, herpes, and diabetes. The potential medicinal effects of Andrographis paniculata are primarily attributed to its active phytoconstituents, which have been extensively studied for their pharmacological uses.
The following article explains in detail what are the medicinal uses of Andrographis paniculata, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.
ARTICLE SUMMARY: The table below summarizes the most crucial information about Andrographis paniculata provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.
| Medicinal Aspect | Summary |
|---|---|
| Uses | Influenza, Fever, Gastroenteritis, Diarrhea, Common cold, Bronchitis, Malaria, Cough, Hepatitis, Sinusitis |
| Benefits | Reduces inflammation, Fights off infections, Suppresses cancer cells, Has anti oxidative, Shows immune boosting, Treats digestive issues, Has anti viral properties, Supports respiratory health, Reduces fever quickly, Has anti bacterial effects |
| Properties | Antimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Immunomodulatory, Analgesic, Antipyretic, Antihistaminic, Antispasmodic, Anti-ulcerative |
| Constituents | Andrographolide, Saponins, Phenolic acids, Neoadrographolide, Flavonoids, Quercetin, Triterpenoids, Kaempferol, Dihydrodehydroandrographolide, Dehydroandrographolide |
| Parts | Leaves, Rhizomes, Roots, Flowers |
| Preparations | Capsule, Tincture, Tea, Decoction, Salve, Suppository |
| Side Effects | Induces, Abnormalities, Increases, Interacts, Enhances, Affects, Aggravates, Triggers, Exacerbates, Worsens |
| Precaution | Consult a healthcare professional before use, Monitor for allergic reactions and interactions, Use under the guidance of a qualified practitioner, Start with a low dose and gradually increase, Avoid during pregnancy and breastfeeding, Be aware of potential interactions with medications, Use with caution in individuals with bleeding disorders, Monitor blood sugar and blood pressure levels, Avoid in individuals with kidney or liver disease, Report any adverse effects to a healthcare professional |
BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Andrographis paniculata. Feel free to download it, print it, and reference it when you need a quick reminder.
- What are the main medicinal uses of Andrographis paniculata?
- Modern Western Medicine
- Traditional Chinese Medicine
- Ayurvedic Medicine
- Unani Medicine
- Homeopathic Medicine
- What are the primary health benefits of Andrographis paniculata?
- Circulatory System
- Digestive System
- Endocrine System
- Integumentary System
- Lymphatic System
- Musculoskeletal System
- Nervous System
- Reproductive System
- Respiratory System
- Urinary System
- What are the dominant therapeutic properties of Andrographis paniculata?
- What are the major healing constituents of Andrographis paniculata?
- What are the most used parts of Andrographis paniculata in medicine?
- What are the most common medicinal preparations of Andrographis paniculata?
- What are the possible side effects of Andrographis paniculata if used improperly?
- What are the precautions to take before using Andrographis paniculata medicinally?
- Are there scientific studies that prove the medical effectiveness of Andrographis paniculata?
- Related herbs to Andrographis paniculata?
What are the main medicinal uses of Andrographis paniculata?
The main medicinal uses of Andrographis paniculata are fever reduction due to its anti-inflammatory and antipyretic properties, attributed to andrographolide and neoandrographolide.
Diarrhea relief is achieved through the plant's ability to inhibit intestinal motility and fluid secretion, thanks to the presence of andrographolide and 14-deoxyandrographolide. Common cold symptoms are alleviated by andrographolide's immunomodulatory effects, which enhance the activity of natural killer cells and macrophages. Andrographis paniculata is also effective in treating gastroenteritis, as its constituents have antimicrobial properties, and in the case of influenza, its anti-inflammatory effects help reduce inflammation and prevent tissue damage.
Additionally, the plant is used to treat cough, inflammation, malaria, hepatitis, and respiratory issues, due to its ability to inhibit the production of pro-inflammatory cytokines and enzymes, as well as its antimicrobial and antioxidant activities.
The following illustration give a summary of the main medicinal uses of Andrographis paniculata.
The list below provide more details on why Andrographis paniculata is used to alleviate the health conditions mentioned in the illustration above.
- Influenza: This plant is used for treating influenza due to its anti-inflammatory and immunomodulatory properties, which help alleviate symptoms such as fever, cough, and body aches.
- Fever: It is used for reducing fever due to its anti-pyretic properties, which help lower body temperature and alleviate symptoms associated with fever.
- Gastroenteritis: This plant is used for treating gastroenteritis due to its anti-inflammatory and anti-bacterial properties, which help alleviate symptoms such as diarrhea, vomiting, and abdominal pain.
- Diarrhea: It is used for treating diarrhea due to its anti-inflammatory and anti-bacterial properties, which help alleviate symptoms such as loose stools and abdominal cramps.
- Common Cold: This plant is used for treating the common cold due to its anti-inflammatory and immunomodulatory properties, which help alleviate symptoms such as cough, runny nose, and sore throat.
- Bronchitis: It is used for treating bronchitis due to its anti-inflammatory and anti-bacterial properties, which help alleviate symptoms such as cough, wheezing, and shortness of breath.
- Malaria: This plant has been traditionally used for treating malaria due to its anti-plasmodial properties, which help reduce the severity of symptoms and shorten the duration of the disease.
- Cough: It is used for treating cough due to its anti-inflammatory and anti-bacterial properties, which help alleviate symptoms such as coughing and wheezing.
- Hepatitis: This plant has been traditionally used for treating hepatitis due to its anti-inflammatory and antioxidant properties, which help reduce liver inflammation and improve liver function.
- Sinusitis: It is used for treating sinusitis due to its anti-inflammatory and anti-bacterial properties, which help alleviate symptoms such as congestion, sinus pressure, and cough.
The table that follows gives an overview of what are the most common health conditions that are treated with Andrographis paniculata, in each of the major medicinal systems.
| Medicinal System | Conditions Treated |
|---|---|
| Modern Western Medicine | Common Cold, Influenza, Gastroenteritis, Bronchitis, Diarrhea, Fever, Sinusitis, Dyspepsia, Cough, Pneumonia, Migraines, Tonsillitis, Malaria, Hepatitis, Respiratory Tract Infections, Urinary Tract Infections, Gastritis, Asthma, Rheumatoid Arthritis, Gastroesophageal Reflux |
| Traditional Chinese Medicine | Influenza, Fever, Gastroenteritis, Diarrhea, Common Cold, Malaria, Bronchitis, Sore Throat, Cold, Hepatitis, Rheumatoid Arthritis, Migraine, Pneumonia, Asthma, Cough, Nausea, Respiratory Infection, Dyspepsia, Sinusitis, Skin Infection |
| Ayurvedic Medicine | Common Cold, Gastroenteritis, Diarrhea, Fever, Malaria, Influenza, Bronchitis, Cough, Typhoid Fever, Hepatitis, Asthma, Pneumonia, Sore Throat, Inflammation, Respiratory Tract Infections, Tonsillitis, Urinary Tract Infection, Sinusitis, Dyspepsia, Arthritis |
| Unani Medicine | Diarrhea, Fever, Influenza, Gastroenteritis, Malaria, Common Cold, Bronchitis, Cough, Sinusitis, Typhoid Fever, Viral Hepatitis, Cold, Respiratory Tract Infections, Gastritis, Asthma, Headache, Sore Throat, Tonsillitis, Dyspepsia, Urinary Tract Infection |
| Homeopathic Medicine | Influenza, Gastroenteritis, Common Cold, Fever, Bronchitis, Diarrhea, Migraines, Colitis, Sinusitis, Hepatitis, Tonsillitis, Pneumonia, Cough, Inflammation, Sore Throat, Urinary Tract Infection, Arthritis, Asthma, Gastritis, Rheumatoid Arthritis |
Modern Western Medicine
In modern western medicine, Andrographis paniculata is used to treat respiratory tract infections, which include common cold, influenza, bronchitis, cough, and pneumonia.
Its efficacy in combating gastrointestinal issues is also recognized, with gastroenteritis, diarrhea, and dyspepsia being addressed through its administration. Furthermore, Andrographis paniculata is employed to alleviate fever, sinusitis, and tonsillitis, showcasing its versatility in treating various health conditions. Additionally, it has been found to be effective in managing asthma, rheumatoid arthritis, and gastritis, while also exhibiting potential benefits for gastritis, hepatitis, and malaria.
Moreover, its immunomodulatory properties have been investigated for the treatment of urinary tract infections, as well as its potential applications in managing migraines, asthma, and gastroesophageal reflux.
Traditional Chinese Medicine
In traditional chinese medicine, Andrographis paniculata is used to treat various health conditions.
It is commonly used to alleviate symptoms of influenza, such as fever and respiratory issues, and also helps to combat gastroenteritis, diarrhea and nausea. The plant is also employed to relieve the discomforts of common cold, bronchitis and sore throat, as well as cold and hepatitis. Additionally, Andrographis paniculata is used to manage the symptoms of rheumatoid arthritis, migraine, pneumonia and asthma, which includes cough and dyspepsia.
Furthermore, it is also used to treat sinusitis, skin infection and respiratory infections, including malaria.
Ayurvedic Medicine
In ayurvedic medicine, Andrographis paniculata is used to treat various health conditions.
It is particularly effective in alleviating symptoms associated with the common cold, such as congestion and cough, which often precede other conditions like bronchitis and pneumonia. Additionally, Andrographis paniculata has been traditionally used to treat gastroenteritis, diarrhea, and fever, which can sometimes progress to more severe conditions like typhoid fever and hepatitis. Furthermore, it has been used to manage malaria, influenza, and dyspepsia, as well as respiratory tract infections, sore throat, inflammation, and tonsillitis.
Its antiviral and anti-inflammatory properties also make it a suitable treatment for urinary tract infections, sinusitis, arthritis, and asthma.
Unani Medicine
In unani medicine, Andrographis paniculata is used to treat various health conditions, including diarrhea, fever, and influenza, as the plant has been found to possess antimicrobial and anti-inflammatory properties that help alleviate symptoms of gastrointestinal infections.
Andrographis paniculata is also used to treat gastroenteritis, malaria, and common cold, which are characterized by inflammation of the gastrointestinal tract and respiratory system. Additionally, it is used to treat bronchitis, cough, sinusitis, and typhoid fever, all of which are associated with respiratory and gastrointestinal issues. Furthermore, it is used to treat viral hepatitis, cold, respiratory tract infections, and gastritis, which are all linked to inflammation and infection.
Moreover, Andrographis paniculata is also used to treat asthma, headache, sore throat, tonsillitis, dyspepsia, urinary tract infection, and other conditions, demonstrating its broad-spectrum therapeutic properties.
Homeopathic Medicine
In homeopathic medicine, Andrographis paniculata is used to treat a variety of health conditions, including influenza, which it has been shown to reduce the severity and duration of.
It is also used to alleviate gastroenteritis symptoms, as well as those associated with the common cold. The herb is effective in reducing fever and alleviating symptoms of bronchitis, and is often used to treat diarrhea, migraines, and colitis. Additionally, it has been used to treat sinusitis, hepatitis, tonsillitis, pneumonia, cough, and inflammation, as well as sore throat and urinary tract infections.
Furthermore, Andrographis paniculata has been studied for its potential in treating a range of other conditions, including arthritis, asthma, gastritis, rheumatoid arthritis.
What are the primary health benefits of Andrographis paniculata?
Andrographis paniculata reduces inflammation by suppressing pro-inflammatory cytokines and enzymes, thereby alleviating symptoms of conditions like arthritis.
The plant fights off infections due to its antimicrobial properties, which inhibit the growth of pathogenic microorganisms and prevent their adherence to host cells. Andrographis paniculata suppresses cancer cells by inducing apoptosis and inhibiting cell proliferation, while its anti-oxidative properties have been shown to scavenge free radicals and reduce oxidative stress. Furthermore, the plant shows immune-boosting effects through the activation of immune cells and the production of cytokines, which also enables it to treat digestive issues by regulating gut motility and secretion.
Andrographis paniculata has anti-viral properties, supports respiratory health by reducing airway inflammation, reduces fever quickly by inducing the production of heat-shock proteins, and exhibits anti-bacterial effects by disrupting bacterial cell membranes, ultimately leading to its efficacy against various diseases.
The following illustration give a summary of the primary health benefits of Andrographis paniculata.
The list below provides more details on why Andrographis paniculata offers the health benefits mentioned in the illustration above.
- Reduces Inflammation: This benefit is due to the presence of andrographolide, a sesquiterpene lactone with anti-inflammatory properties, which inhibits the production of pro-inflammatory cytokines and enzymes, thereby reducing inflammation and alleviating conditions such as arthritis and other inflammatory diseases.
- Fights Off Infections: The plant's antimicrobial properties, particularly its ability to inhibit the growth of bacteria and viruses, contribute to its benefit in fighting off infections by targeting the pathogen and preventing its replication, thereby reducing the severity and duration of illnesses such as the common cold and flu.
- Suppresses Cancer Cells: Studies have shown that the plant's active compounds, including andrographolide, have the ability to induce apoptosis and inhibit the proliferation of cancer cells, making it a potential agent in the treatment and prevention of certain types of cancer, such as lung and breast cancer.
- Has Anti Oxidative: The plant's antioxidant properties, attributed to its polyphenolic compounds, help neutralize free radicals and reduce oxidative stress, thereby protecting cells from damage and preventing conditions such as atherosclerosis and neurodegenerative diseases.
- Shows Immune Boosting: The plant's ability to stimulate the immune system, particularly its effect on macrophages and natural killer cells, enhances the body's defense against pathogens and promotes immune function, thereby reducing the risk of infections and autoimmune diseases.
- Treats Digestive Issues: The plant's anti-inflammatory and antimicrobial properties contribute to its benefit in treating digestive issues, such as irritable bowel syndrome and gastroenteritis, by reducing inflammation and eliminating pathogens in the gastrointestinal tract.
- Has Anti Viral Properties: The plant's ability to inhibit the replication of viruses, particularly its effect on the herpes simplex virus, makes it a potential agent in the treatment and prevention of viral infections, such as herpes and HIV.
- Supports Respiratory Health: The plant's expectorant properties, attributed to its glycosides and terpenoids, help loosen and clear mucus from the respiratory tract, thereby alleviating conditions such as bronchitis and asthma.
- Reduces Fever Quickly: The plant's ability to reduce fever is attributed to its antipyretic properties, which inhibit the production of pro-inflammatory cytokines and enzymes, thereby alleviating the symptoms of fever and reducing body temperature.
- Has Anti Bacterial Effects: The plant's antibacterial properties, particularly its effect on gram-positive bacteria, contribute to its benefit in treating bacterial infections, such as urinary tract infections and skin infections.
The table that follows gives an overview of what are the primary health benefits of Andrographis paniculata for each of the major body system.
| Body System | Health Benefits |
|---|---|
| Circulatory System | Reduces Blood Pressure, Improves Circulation Flow, Enhances Vascular Health, Prevents Blood Clotting, Lowers Ldl Levels, Increases Red Blood Cells, Boosts Oxygen Supply, Improves Cardiac Function, Reduces Inflammation Risk, Improves Endothelial Health |
| Digestive System | Reduces Inflammation, Soothes Digestive, Improves Gut Health, Enhances Digestive Enzyme, Relieves Gastrointestinal, Protects Gut Lining, Reduces Bloating Pains, Cures Ulcerative Colitis, Prevents Irritable Bowel, Fights Intestinal Parasites |
| Endocrine System | Regulates Adrenal Hormones, Balances Thyroid Function, Supports Pancreatic Health, Stimulates Insulin Sensitivity, Boosts Cortisol Levels, Reduces Inflammation Hormones, Maintains Gonadal Balance, Improves Metabolic Rate, Enhances Androgen Production, Promotes Adrenal Adaptation |
| Integumentary System | Fights Skin Inflammation, Reduces Acne Formation, Soothes Irritated Skin, Prevents Sun Damage, Cures Skin Infections, Heals Wound Tissues, Safeguards Skin Integrity, Relaxes Muscle Tension, Protects Skin Barrier, Removes Dead Skin |
| Lymphatic System | Boosts Lymph Flow, Reduces Inflammation, Stimulates Detoxification, Improves Immune Function, Enhances Filtration, Activates Cell Cleaning, Increases White Blood Cell Count, Reduces Swelling, Improves Waste Removal, Regulates Lymph Node Activity |
| Musculoskeletal System | Reduces Inflammation, Relieves Pain, Soothes Joints, Prevents Arthritis, Heals Tendons, Strengthen Bones, Lowers Oxidation, Improves Mobility, Eases Stiffness, Promotes Recovery |
| Nervous System | Reduces Anxiety, Stabilizes Mood, Soothes Nerves, Relaxes Muscles, Eases Tension, Calms Brain, Prevents Fatigue, Improves Sleep, Boosts Energy, Enhances Focus |
| Reproductive System | Reduce Inflammation, Improve Fertility, Regulate Hormones, Strengthen Immune, Increase Libido, Enhance Reproductive, Treat Endometriosis, Prevent Miscarriage, Support Menstruation, Promote Ovulation |
| Respiratory System | Reduce Inflammation, Prevent Congestion, Combat Bacterial, Relieve Allergy, Soothe Bronchitis, Clear Mucus, Fight Infections, Mitigate Asthma, Treat Coughs, Alleviate Wheezing |
| Urinary System | Prevents Kidney Damage, Reduces Urine Infections, Treats Urinary Tract Infections, Relieves Bladder Strains, Enhances Urine Flow, Prevents Urine Retention, Cures Kidney Stones, Treats Prostate Enlargement, Reduces Bladder Inflammation, Prevents Urine Leaks |
Circulatory System
Andrographis paniculata reduces blood pressure through its anti-inflammatory and antioxidant properties, which help to mitigate the negative effects of high blood pressure on the cardiovascular system.
Its ability to improve circulation flow is also attributed to its vasodilatory effects, which help to relax blood vessels and increase blood flow. Furthermore, Andrographis paniculata enhances vascular health by reducing oxidative stress and improving the function of endothelial cells, the inner lining of blood vessels. Additionally, the plant prevents blood clotting by inhibiting the activity of platelets and reducing the production of thromboxane, a key player in blood clot formation, thereby lowering the risk of cardiovascular events.
By increasing red blood cells and boosting oxygen supply to the body's tissues, Andrographis paniculata improves cardiac function and reduces inflammation risk, ultimately improving endothelial health.
The medicinal benefits of Andrographis paniculata on the circulatory system help relieving the health conditions listed below.
- High blood pressure
- Cardiac arrhythmia
- Atherosclerosis
- Varicose veins
- Deep vein thrombosis
- Raynaud's disease
- Cardiac failure
- Pulmonary embolism
Digestive System
Andrographis paniculata reduces inflammation by inhibiting the production of pro-inflammatory cytokines through its anti-inflammatory properties.
Soothing digestive issues is another key benefit, attributed to its antimicrobial properties that combat pathogens in the gut. Improving gut health is facilitated by its antioxidant properties, which protect the gut from oxidative stress and damage caused by free radicals. Enhancing digestive enzyme production is a result of its anti-oxidative properties, which support the optimal functioning of digestive enzymes.
The plant's anti-inflammatory and antimicrobial properties also relieve gastrointestinal issues, protect the gut lining from damage, reduce bloating pains, cure ulcerative colitis, prevent irritable bowel syndrome, and fight intestinal parasites by eliminating pathogens and promoting a healthy gut microbiome.
The medicinal benefits of Andrographis paniculata on the digestive system help relieving the health conditions listed below.
- Nausea
- Vomiting
- Diarrhea
- Gastroenteritis
- Ulcerative colitis
Endocrine System
Andrographis paniculata regulates adrenal hormones by modulating the production of cortisol and other glucocorticoids, which helps to mitigate the effects of chronic stress on the endocrine system.
This plant balances thyroid function by stimulating the release of thyroid-stimulating hormone, thereby maintaining optimal levels of thyroxine and triiodothyronine. Andrographis paniculata supports pancreatic health by protecting the islet cells from oxidative damage and inflammation, thereby preserving insulin production and glucose homeostasis. Additionally, it stimulates insulin sensitivity by improving the translocation of glucose transporter 4 and enhancing the activity of AMP-activated protein kinase, which helps to lower blood glucose levels.
By reducing inflammation hormones such as prostaglandins and leukotrienes, Andrographis paniculata maintains gonadal balance, improves metabolic rate, boosts cortisol levels, enhances androgen production, and promotes adrenal adaptation.
The medicinal benefits of Andrographis paniculata on the endocrine system help relieving the health conditions listed below.
- Polycystic ovary syndrome
- Hirsutism
- Hyperglycemia
- Hypothyroidism
- Menopause
- Erectile dysfunction
Integumentary System
Andrographis paniculata fights skin inflammation due to its anti-inflammatory property, which inhibits the production of pro-inflammatory mediators.
Reducing acne formation is also a benefit of this plant, attributed to its antimicrobial properties that suppress the growth of Propionibacterium acnes. Soothing irritated skin is a result of Andrographis paniculata's antioxidant activity, which neutralizes free radicals and reduces oxidative stress. Preventing sun damage and curing skin infections are linked to the plant's antioxidant and antimicrobial properties, respectively.
The combination of its antioxidant, anti-inflammatory, and antimicrobial properties also enables Andrographis paniculata to heal wound tissues, relax muscle tension, protect skin barrier, safeguard skin integrity, and remove dead skin.
The medicinal benefits of Andrographis paniculata on the integumentary system help relieving the health conditions listed below.
- Acne
- Psoriasis
- Eczema
- Wound healing
- Skin infections
- Dandruff
Lymphatic System
Andrographis paniculata boosts lymph flow by inducing the contraction of lymphatic smooth muscle cells, which increases the movement of lymph fluid through the body.
The anti-inflammatory properties of this plant reduce inflammation in the lymphatic system, thereby alleviating lymphedema and promoting the efficient removal of waste. Additionally, its antimicrobial properties stimulate detoxification by eliminating pathogens from the lymphatic system, which helps to maintain immune function and prevent the spread of disease. Furthermore, Andrographis paniculata enhances filtration by increasing the expression of lymphatic transporters, which improves the removal of waste products and toxins from the body.
The antioxidant and anti-inflammatory properties of this plant also activate cell cleaning, increase white blood cell count, reduce swelling, improve waste removal, and regulate lymph node activity, thereby supporting the optimal functioning of the lymphatic system.
The medicinal benefits of Andrographis paniculata on the lymphatic system help relieving the health conditions listed below.
- Lymphadenitis
- Lymphedema
- Edema
- Lymphangitis
- Fibromyalgia
- Tonsillitis
- Lymphoma
- Gingivitis
- Sinusitis
- Thyroiditis
Musculoskeletal System
Andrographis paniculata reduces inflammation through its anti-inflammatory and antioxidant properties, which are responsible for its ability to suppress the production of pro-inflammatory cytokines and enzymes.
This reduction in inflammation in turn relieves pain by modulating the activity of nociceptors and inhibiting the release of pain mediators. Andrographis paniculata soothes joints by reducing the production of pro-inflammatory cytokines and enzymes, thereby alleviating joint inflammation and damage. The anti-arthritic properties of Andrographis paniculata prevent arthritis by inhibiting the production of pro-inflammatory cytokines and enzymes, and by promoting the production of anti-inflammatory cytokines.
Andrographis paniculata heals tendons by promoting collagen synthesis and reducing inflammation, and also strengthens bones by inhibiting the activity of osteoclasts and promoting the activity of osteoblasts, which lowers oxidation and improves mobility.
The medicinal benefits of Andrographis paniculata on the musculoskeletal system help relieving the health conditions listed below.
- Osteoarthritis
- Rheumatoid arthritis
- Tendinitis
- Fibromyalgia
- Muscle spasm
- Injury recovery
- Gout
- Ligament sprain
Nervous System
Andrographis paniculata reduces anxiety by exerting a sedative effect on the nervous system due to its flavonoids and andrographolide content, which have a tranquilizing effect on the brain.
Stabilizing mood is achieved through the andrographolide's ability to modulate the neurotransmitter serotonin, thereby regulating emotional responses. Soothing nerves is facilitated by the antioxidant properties of Andrographis paniculata, which protect neurons from oxidative stress and damage. The anti-inflammatory properties of andrographolide also contribute to relaxing muscles and easing tension by reducing inflammation in the body's musculature.
Calming the brain, preventing fatigue, improving sleep, boosting energy, and enhancing focus are all linked to the plant's ability to modulate the body's stress response and increase the production of neurotransmitters such as dopamine and acetylcholine.
The medicinal benefits of Andrographis paniculata on the nervous system help relieving the health conditions listed below.
- Anxiety
- Stress
- Depression
- Insomnia
- Panic disorder
- Addiction
- Chronic fatigue
- Gastrointestinal disorders
Reproductive System
Andrographis paniculata reduce inflammation through its anti-inflammatory properties, which help alleviate the symptoms of endometriosis, a condition characterized by the growth of endometrial tissue outside the uterus.
This plant also improve fertility by enhancing reproductive health, thanks to its antioxidant properties, which protect the reproductive cells from oxidative stress and damage. Regulate hormones is another benefit of Andrographis paniculata, as it contains compounds that modulate the hormonal balance in the body, supporting menstruation and promoting ovulation. Strengthen immune function is essential for preventing miscarriage, and Andrographis paniculata's immunomodulatory properties help boost the immune system's ability to fight off infections and support a healthy pregnancy.
Additionally, the plant's anti-microbial and anti-estrogenic properties increase libido, treat endometriosis, and support reproductive health, allowing couples to conceive naturally.
The medicinal benefits of Andrographis paniculata on the reproductive system help relieving the health conditions listed below.
- Polycystic ovary syndrome
- Endometriosis
- Premenstrual syndrome
- Mittelschmerz
- Male infertility
- Erectile dysfunction
- Menstrual cramps
- Menopausal symptoms
Respiratory System
Andrographis paniculata reduce inflammation by exerting anti-inflammatory properties, which in turn prevent congestion by relaxing bronchial muscles and improving airflow.
Its antimicrobial properties combat bacterial infections, while also relieving allergy symptoms by inhibiting the release of histamine and other allergenic compounds. Andrographis paniculata soothe bronchitis by reducing the production of pro-inflammatory cytokines and promoting the clearance of mucus, a process that also helps clear mucus from the airways. Furthermore, its immunomodulatory properties fight infections by enhancing the activity of natural killer cells and activating the immune system, thereby mitigating asthma symptoms and alleviating wheezing.
By possessing anti-oxidant properties, Andrographis paniculata also treat coughs by reducing oxidative stress and inflammation in the respiratory tract.
The medicinal benefits of Andrographis paniculata on the respiratory system help relieving the health conditions listed below.
- Bronchitis
- Asthma
- Sinusitis
- Cough
- Pneumonia
- Influenza
- Tonsillitis
Urinary System
Andrographis paniculata prevents kidney damage by its antioxidant properties, which neutralize free radicals that cause oxidative stress to renal cells.
This herb reduces urine infections through its antimicrobial properties, inhibiting the growth of pathogenic bacteria in the urinary tract. It treats urinary tract infections by its anti-inflammatory properties, reducing inflammation and promoting healing in the infected tissues. Andrographis paniculata relieves bladder strains due to its adaptogenic properties, which help the body adapt to stress and promote balance in the urinary system.
Its diuretic properties also enhance urine flow, prevent urine retention, cure kidney stones, treat prostate enlargement, reduce bladder inflammation, and prevent urine leaks.
The medicinal benefits of Andrographis paniculata on the urinary system help relieving the health conditions listed below.
- Urinary tract infections
- Kidney stones
- Prostatitis
- Polycystic kidney disease
- Kidney failure
- Benign prostatic hyperplasia
What are the dominant therapeutic properties of Andrographis paniculata?
The therapeutic properties of Andrographis paniculata are attributed to its broad spectrum of bioactive compounds, including andrographolide, a diterpenoid lactone responsible for its antimicrobial properties, allowing it to inhibit the growth of various pathogens.
This plant also exhibits antioxidant properties, scavenging free radicals and protecting against oxidative stress-induced damage, which is attributed to the presence of flavonoids and phenolic acids. Furthermore, the anti-inflammatory activity of Andrographis paniculata is associated with the inhibition of pro-inflammatory enzymes and cytokines, demonstrating its potential in treating inflammatory conditions. Additionally, it possesses antiviral properties, as andrographolide has been shown to inhibit viral replication and prevent the development of viral infections.
The immunomodulatory, analgesic, antipyretic, antihistaminic, antispasmodic, and anti-ulcerative properties of Andrographis paniculata are also attributed to its bioactive compounds, which work synergistically to provide therapeutic benefits in various diseases.
The following illustration give a summary of the dominant therapeutic properties of Andrographis paniculata.
The list below provides more details on why Andrographis paniculata has the therapeutic properties mentioned in the illustration above.
- Antimicrobial: Andrographis paniculata has been found to exhibit antimicrobial properties, inhibiting the growth of various bacteria, including Staphylococcus aureus and Escherichia coli, by interfering with their cell membrane integrity.
- Antioxidant: Andrographis paniculata contains antioxidants such as flavonoids and phenolic acids, which have been shown to scavenge free radicals and protect against oxidative stress, potentially reducing the risk of chronic diseases like cancer and neurodegeneration.
- Anti-Inflammatory: Andrographis paniculata has anti-inflammatory properties, which are attributed to the presence of andrographolide, a diterpenoid lactone that inhibits the production of pro-inflammatory cytokines and enzymes, thereby reducing inflammation and tissue damage.
- Antiviral: Andrographis paniculata has been found to exhibit antiviral activity against certain viruses, including herpes simplex virus and HIV, by inhibiting viral replication and reducing the production of viral proteins.
- Immunomodulatory: Andrographis paniculata has immunomodulatory effects, enhancing the activity of immune cells such as macrophages and natural killer cells, and increasing the production of cytokines, which helps to boost the immune system and protect against infections.
- Analgesic: Andrographis paniculata has been found to exhibit analgesic properties, reducing pain by inhibiting the production of pro-inflammatory cytokines and enzymes, and modulating the activity of pain-sensing neurons.
- Antipyretic: Andrographis paniculata has antipyretic properties, reducing fever by inhibiting the production of pro-inflammatory cytokines and enzymes, and modulating the activity of hypothalamic neurons involved in temperature regulation.
- Antihistaminic: Andrographis paniculata has been found to exhibit antihistaminic properties, inhibiting the release of histamine from mast cells and reducing allergic responses.
- Antispasmodic: Andrographis paniculata has been found to exhibit antispasmodic properties, relaxing smooth muscle and reducing muscle spasms by inhibiting the release of acetylcholine and other neurotransmitters involved in muscle contraction.
- Anti-Ulcerative: Andrographis paniculata has anti-ulcerative properties, protecting against stomach ulcers by inhibiting the production of gastric acid and reducing inflammation in the gastric mucosa.
What are the major healing constituents of Andrographis paniculata?
The following illustration give a summary of the major healing consitutents of Andrographis paniculata.
The list below provides more details on what are the major healing constituents of Andrographis paniculata and why they are important for health.
- Andrographolide: A diterpenoid lactone with anti-inflammatory, antioxidant, and immunomodulatory properties.
- Saponins: Saponins are a type of compound found in Andrographis paniculata with surfactant and emulsifying properties.
- Phenolic acids: Phenolic acids are a class of bioactive compounds found in Andrographis paniculata, characterized by their antioxidant, anti-inflammatory, and free radical-scavenging properties.
- Neoadrographolide: Neoadrographolide is a diterpenoid lactone with anti-inflammatory and immunomodulatory properties.
- Flavonoids: Flavonoids are a class of plant compounds that include kaempferol and quercetin, exhibiting antioxidant and anti-inflammatory properties.
- Quercetin: Quercetin is a flavonoid antioxidant with anti-inflammatory, anti-viral, and anti-bacterial properties, and is also an anti-oxidant and a scavenger of reactive oxygen species.
- Triterpenoids: Triterpenoids from Andrographis paniculata are known for their antioxidant, anti-inflammatory, and immunomodulatory properties.
- Kaempferol: Kaempferol is a flavonoid with antioxidant, anti-inflammatory and anti-cancer properties.
- Dihydrodehydroandrographolide: A lactone constituent of Andrographis paniculata, exhibiting anti-inflammatory and immunomodulatory properties.
- Dehydroandrographolide: A bioactive constituent of Andrographis paniculata, known to possess anti-inflammatory and immunomodulatory properties.
The table that follows estimates the relative concentrations of the main medicinal constituents contained in Andrographis paniculata and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.
| Constituent | Concentration | Properties |
|---|---|---|
| Andrographolide | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Antipyretic, Immunomodulatory, Anticancer |
| Saponins | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antibacterial, Antifungal, Anti-diabetic |
| Phenolic acids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Anticancer, Cardioprotective, Antihypertensive |
| Neoadrographolide | LOW | Anti-inflammatory, Antioxidant, Antimicrobial |
| Flavonoids | LOW | Antioxidant, Anti-inflammatory, Antimicrobial, Antiviral, Antibacterial, Analgesic, Pain relief, Antioxidant, Anticancer, Cardioprotective, Vasodilator |
| Quercetin | LOW | Antioxidant, Anti-inflammatory, Antimicrobial, Anticancer, Antiviral, Anti-allergic, Anti-histamine, Cardioprotective, Vasodilator, Anti-diabetic |
| Triterpenoids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Immunomodulatory, Antiviral |
| Kaempferol | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antihistamine, Cardioprotective, Vasodilator, Neuroprotective |
| Dihydrodehydroandrographolide | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Anticancer |
| Dehydroandrographolide | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Antipyretic, Analgesic, Immunomodulatory |
What are the most used parts of Andrographis paniculata in medicine?
The most used parts of Andrographis paniculata for medicinal purposes are leaves, rhizomes, and roots.
The leaves contain flavonoids, andrographolides, and phenolic acids, which exhibit anti-inflammatory, antioxidant, and antimicrobial properties. The rhizomes contain andrographolides, flavonoids, and phenolic acids, with anti-inflammatory, antioxidant, and immunomodulatory properties. The roots contain lignans, flavonoids, and phenolic acids, which have anti-inflammatory, antioxidant, and antiviral properties.
These bioactive compounds contribute to the medicinal properties of Andrographis paniculata, including anti-inflammatory, antioxidant, and antimicrobial effects.
The following illustration give a summary of the most used parts of Andrographis paniculata in medicine.
The list below provides more details on what are the most used parts of Andrographis paniculata in medicine and why.
- Leaves: The leaves of this plant are rich in bioactive compounds, including andrographolide, andrographisne, and neoadrographolide, which exhibit anti-inflammatory, antioxidant, and immunomodulatory properties, providing primary health benefits such as reducing fever, alleviating respiratory tract infections, and protecting against liver damage.
- Rhizomes: The rhizomes of this plant contain andrographolide, andrographisne, and 14-deoxyandrographolide, which possess anti-inflammatory, antipyretic, and immunomodulatory properties, offering primary health benefits including reducing inflammation, alleviating fever, and enhancing immune function.
- Roots: The roots of this plant are rich in bioactive compounds, including andrographolide, andrographisne, and 14-deoxyandrographolide, which exhibit anti-inflammatory, antioxidant, and immunomodulatory properties, providing primary health benefits such as reducing inflammation, protecting against oxidative stress, and modulating immune responses.
The table that follows gives a more complete list of healing constituents found in each part of Andrographis paniculata mentioned above.
| Part | Constituents |
|---|---|
| Leaves | Andrographolide, Neoandrographolide, Dehydroandrographolide, Vasak, Palmitic acid, Stearic acid, Oleanolic acid, Ursolic acid, Luteolin, Apigenin, Quercetin |
| Rhizomes | Andrographolide, Andrographisne, Neoadrographolide, Dehydroandrographolide, Palmaric acid, Sesquiterpenoids, Phenolic acids, Volatile oil |
| Roots | Andrographolide, Neoadrographolide, Andrographis neoadjuvant, Palmitic acid, Oleic acid, Stigmasterol, Beta-sitosterol, Ursolic acid, Triterpene acids |
What are the most common medicinal preparations of Andrographis paniculata?
The most common herbal preparation of Andrographis paniculata for medicinal purposes are capsules, which contain a standardized extract of the plant's bioactive compounds, such as andrographolide, and are used to treat various conditions, including fever and respiratory infections.
The tincture, a concentrated liquid extract, is often used for its anti-inflammatory properties and is applied topically to relieve pain and swelling. Andrographis tea, made by infusing the dried leaves in hot water, is commonly consumed to alleviate symptoms of gastrointestinal disorders, such as nausea and diarrhea, and to boost the immune system. A decoction, a type of tea made by boiling the dried roots in water, is traditionally used in Ayurvedic medicine to treat conditions like arthritis and gout.
The salve, a topical ointment, and the suppository, a rectal medication, are less common preparations of Andrographis paniculata, but are used to deliver the plant's anti-inflammatory and antiviral compounds directly to the affected area.
The following illustration give a summary of the most common medicinal preparations of Andrographis paniculata.
The list below provides more details on what are the most common medicinal preparations of Andrographis paniculata and what are their main uses.
- Capsule: Capsule made from this plant is used to treat fever, upper respiratory tract infections, and gastrointestinal issues, and also as an anti-inflammatory and antioxidant agent.
- Tincture: Tincture made from this plant is used to treat upper respiratory tract infections, reduce inflammation, and alleviate symptoms associated with the common cold and flu.
- Tea: Tea made from this plant is used for fever reduction, anti-inflammatory and immune system support, and for the treatment of respiratory tract infections, such as the common cold and flu.
- Decoction: Decoction made from this plant is used to treat fever, respiratory tract infections, and as an anti-inflammatory agent.
- Salve: Salve made from this plant is used topically to treat fever, sore throat, and respiratory infections, and also for its anti-inflammatory and antimicrobial properties.
The table that follows shows what are the most used parts of Andrographis paniculata for each medicinal preparation.
| Preparation | Parts |
|---|---|
| Capsule | Leaves, Roots |
| Tincture | Rhizomes, Roots, Leaves |
| Tea | Roots, Leaves |
| Decoction | Roots, Leaves, Rhizomes |
| Salve | Roots, Rhizomes, Leaves |
Capsule
Andrographis paniculata capsule is widely used to treat various conditions such as common cold, flu, sinusitis, gastroenteritis, bronchitis, urinary tract infection, diarrhea, malaria, and hepatitis.
It's a very common herbal preparation, often used in traditional medicine. Its anti-inflammatory effect is a very common outcome of taking Andrographis paniculata capsule. The preparation is made from the leaves and roots of the Andrographis paniculata plant.
Making Andrographis paniculata capsule is moderately difficult as it requires careful processing of the plant material to extract its active compounds.
Below you find a 5-step quick procedure to make effective medicinal Andrographis paniculata capsule.
- Harvest fresh Andrographis paniculata leaves and roots, and clean them thoroughly.
- Dry the leaves and roots in a shaded area or using a food dehydrator to preserve their potency.
- Grind the dried leaves and roots into a fine powder using a mortar and pestle or a spice grinder.
- Mix the ground leaves and roots powder with a binding agent such as gelatin or starch to create a uniform blend.
- Fill empty capsules with the herbal blend and seal them tightly to preserve the medicinal properties.
Tincture
Andrographis paniculata tincture is a herbal remedy used to treat a range of illnesses including flu, common cold, dengue fever, gastroenteritis, malaria, bronchitis, hepatitis, and pneumonia.
It is a widely used preparation in traditional medicine, often in combination with other herbs, and is commonly found in health food stores and online. One of the most notable effects of andrographis paniculata tincture is its ability to reduce inflammation and alleviate symptoms of respiratory tract infections. The preparation is typically made from the rhizomes, roots, and leaves of the Andrographis paniculata plant, which are extracted and mixed with a solvent to create the tincture.
The process of making andrographis paniculata tincture is moderately difficult, requiring careful selection and preparation of the plant materials, as well as precise control over the extraction and solvent ratios.
Below you find an image of Andrographis paniculata tincture.
Below you find a 5-step quick procedure to make effective medicinal Andrographis paniculata tincture.
- Harvest and clean the rhizomes, roots, and leaves of Andrographis paniculata.
- Dry the harvested plant material in a well-ventilated area or using a food dehydrator.
- Combine the dried rhizomes, roots, and leaves in a ratio suitable for tincture production.
- Steep the combined plant material in a solvent such as ethanol or glycerin for an extended period, usually several weeks.
- Strain and filter the tincture to remove the plant material, then bottle and store the final product in a cool, dark place.
Tea
Andrographis paniculata tea is a widely used herbal remedy for various health issues, including the common cold, influenza, migraine, diarrhea, fatigue, gastroenteritis, sinusitis, and bronchitis.
It's one of the most common herbal teas consumed globally due to its effectiveness and easy accessibility. A common effect of consuming this tea is the reduction of inflammation, which contributes to its therapeutic benefits. The tea is typically made from the roots and leaves of the Andrographis paniculata plant, which are mixed with hot water to create a soothing and medicinal brew.
This preparation is also relatively easy to make at home, as it requires minimal ingredients and equipment.
Below you find an image of Andrographis paniculata tea.
Below you find a 5-step quick procedure to make effective medicinal Andrographis paniculata tea.
- Gather 1 ounce of Andrographis paniculata roots and 2 ounces of leaves from a reputable source.
- Rinse the roots and leaves with filtered water to remove any dirt or debris.
- Combine the roots and leaves in a large pot and add 4 cups of filtered water.
- Bring the mixture to a boil, then reduce the heat and let it simmer for 10-15 minutes.
- Strain the liquid and discard the solids, then let the tea cool before serving.
Decoction
Andrographis paniculata decoction is a traditional herbal remedy used to treat various health conditions, including malaria, fever, cough, chikungunya, inflammation, diarrhea, common cold, stomachache and sore throat.
It is a widely used preparation in many parts of the world. The decoction has a common effect of reducing inflammation and fever. The preparation is made from the roots, leaves and rhizomes of the Andrographis paniculata plant.
The decoction is moderately difficult to make, requiring careful measurement of the plant parts and a specific brewing process to extract the active compounds.
Below you find a 5-step quick procedure to make effective medicinal Andrographis paniculata decoction.
- Gather fresh roots, leaves, and rhizomes of Andrographis paniculata plant.
- Wash the roots, leaves, and rhizomes thoroughly with clean water to remove any dirt or debris.
- Combine the roots, leaves, and rhizomes in a large pot and add enough water to cover them completely.
- Bring the mixture to a boil, then reduce the heat and simmer for about 30 minutes to allow the flavors to infuse.
- Strain the decoction through a fine-mesh sieve or cheesecloth into a clean container, discarding the solids.
Salve
Andrographis paniculata salve is a herbal preparation used to treat various health issues, including inflammation, pain, digestive problems, respiratory issues, fatigue, skin conditions, immune system imbalances, and stress.
This preparation is less commonly used compared to other herbal remedies. It has been found to have a unique effect on the body's ability to fight off pathogens and reduce inflammation. The salve is typically made from the roots, rhizomes, and leaves of the Andrographis paniculata plant.
The process of creating this salve can be moderately difficult, requiring precise extraction and combination of the plant's components to achieve the desired potency.
Below you find an image of Andrographis paniculata salve.
Below you find a 5-step quick procedure to make effective medicinal Andrographis paniculata salve.
- Harvest Andrographis paniculata roots and rhizomes, then dry them in a warm, well-ventilated area.
- Combine 1 part dried roots and rhizomes with 2 parts dried leaves in a large bowl.
- Infuse the mixture in a carrier oil, such as coconut or olive oil, in a double boiler for 2-3 hours.
- Strain the oil mixture through a cheesecloth into a clean bowl, discarding the solids.
- Mix in a thickening agent, such as beeswax, and pour the salve mixture into small containers to cool and solidify.
What are the possible side effects of Andrographis paniculata if used improperly?
The possible side effects of improperly using Andrographis paniculata are inducing liver damage due to its hepatotoxic properties, and abnormalities in liver function tests have been reported in some individuals.
Improper use can also increase the risk of bleeding in people taking anticoagulant medications or experiencing bleeding disorders, which may lead to serious complications. Additionally, Andrographis paniculata may interact with certain medications, such as blood thinners and diabetes medications, causing adverse effects or reducing their efficacy. Its immunomodulatory properties can enhance the body's immune response, but excessive consumption may affect kidney function, particularly in individuals with pre-existing kidney disease.
Furthermore, improperly using Andrographis paniculata may aggravate existing conditions, such as gastroesophageal reflux disease (GERD), and trigger allergic reactions in sensitive individuals, exacerbating symptoms and worsening the quality of life.
The most common side effects Andrographis paniculata gives people when used improperly are listed below, along with a brief explanation.
- Induces: Andrographis paniculata induces nausea in some individuals.
- Abnormalities: Andrographis paniculata use has been associated with various abnormalities in pregnant women including birth defects.
- Increases: Levels in serum.
- Interacts: Andrographis paniculata interacts with warfarin, resulting in increased anticoagulant effect.
- Enhances: Andrographis paniculata enhances immune system function.
- Affects: Increases risk of bleeding in patients taking anticoagulant medications.
- Aggravates: Hepatic encephalopathy in patients with liver disease is aggravated.
- Triggers: Hemorrhage in patients taking warfarin and andrographis paniculata
- Exacerbates: Gastrointestinal symptoms are worsened
- Worsens: Andrographis paniculata exacerbates peptic ulcers in susceptible individuals.
What are the precautions to take before using Andrographis paniculata medicinally?
The precautions to take before using Andrographis paniculata medicinally are to consult a healthcare professional before use, especially for individuals with underlying medical conditions.
Additionally, it is crucial to monitor for allergic reactions and interactions with other medications, as this plant may exacerbate conditions such as bleeding disorders, which requires cautious use in these individuals. Moreover, using Andrographis paniculata under the guidance of a qualified practitioner is essential to ensure proper dosing and to avoid potential adverse effects, including changes in blood sugar and blood pressure levels, which necessitates close monitoring of these levels. Furthermore, individuals with kidney or liver disease should avoid using this plant, and those who are pregnant or breastfeeding are also advised to refrain from using it, due to the potential risks to the fetus or baby.
Finally, it is vital to report any adverse effects to a healthcare professional, and to start with a low dose and gradually increase as needed, under the guidance of a qualified practitioner.
The most important precautions you must take before using Andrographis paniculata for medicinal purposes are listed below, along with a brief explanation.
- Consult A Healthcare Professional Before Use: Interactions with medications for diabetes, blood thinners, and certain immunosuppressants may occur.
- Monitor For Allergic Reactions And Interactions: Allergic reactions and interactions with medications such as blood thinners, diabetes medications, and immunosuppressants can occur.
- Use Under The Guidance Of A Qualified Practitioner: Administered only by a healthcare professional due to potential hepatotoxicity and interactions with medications.
- Start With A Low Dose And Gradually Increase: Begin with a dose of 300 mg of Andrographis paniculata extract standardized to 30% andrographolide, and incrementally increase as tolerated and under medical supervision.
- Avoid During Pregnancy And Breastfeeding: Andrographis paniculata may cause uterine stimulation and induce labor, posing a risk to both mother and fetus.
- Be Aware Of Potential Interactions With Medications: Andrographis paniculata may interact with blood thinners, diabetes medications, and other drugs, affecting their efficacy or increasing the risk of adverse effects.
- Use With Caution In Individuals With Bleeding Disorders: Andrographis paniculata may exacerbate bleeding disorders due to its effect on platelet aggregation.
- Monitor Blood Sugar And Blood Pressure Levels: Patients with diabetes or hypertension should monitor their blood sugar and blood pressure levels due to Andrographis paniculata's potential hypoglycemic and hypotensive effects.
- Avoid In Individuals With Kidney Or Liver Disease: Use is contraindicated in individuals with pre-existing kidney or liver disease due to increased risk of toxicity and exacerbation of existing conditions.
- Report Any Adverse Effects To A Healthcare Professional: Inform a healthcare professional about any adverse effects experienced when using Andrographis paniculata.
Are there scientific studies that prove the medical effectiveness of Andrographis paniculata?
Yes, there are several scientific studies that prove the medicianl effectiveness of Andrographis paniculata. Here are some studies that are worthy of notice.
According to a study published by Phytotherapy Research: PTR, the extract of Andrographis paniculata exhibited a significant alteration in behaviour pattern, indicating a potential positive effect on mood regulation. Additionally, it reduced spontaneous motility, suggesting a possible calming effect on the body. Furthermore, the extract prolonged the sleep duration in experimental models, which may contribute to improved sleep quality.
In another study published by Phytomedicine: international journal of phytotherapy and phytopharmacology, the standardized extract of Andrographis paniculata (SHA-10) showed a highly significant improvement in symptoms of upper-respiratory tract infections, particularly throat symptoms and signs, in patients who took the extract for a few days. This improvement was evident in both the total symptom score and total diagnosis score, as compared to the placebo group. Overall, the study suggests that Andrographis paniculata can be an effective treatment for uncomplicated upper-respiratory tract infections, with notable benefits for throat health.
A different research published by Phytotherapy Research: PTR, Andrographis paniculata has been found to possess numerous therapeutic actions, including anti-inflammatory, antioxidant, anticancer, antimicrobial, and antihyperglycemic properties. These properties suggest that it may be effective in treating various health conditions, such as cold and fever, sore throat, and sore tongue. Additionally, the major ingredient andrographolide in this herb reveals significant therapeutic actions that may contribute to its efficacy.
