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Updated: Jul 21, 2024

10 Possible Side Effects Of Achillea Millefolium (Yarrow)

achillea millefolium

Achillea millefolium has some side effects when used improperly, such as allergic reactions, gastrointestinal issues, and increased bleeding risk.

The causes of these side effects include overdose, interactions with medications, and sensitivity to the herb's constituents.

For example, excessive use can worsen conditions like ulcers, gastritis, and even lead to anemia in individuals with bleeding disorders.

This article explains in details the 10 most common side effects of Achillea millefolium if used imporperly.

1. Causes kidney damage

Achillea millefolium causes allergic reactions due to its ability to stimulate the body's immune system and release histamine.

The plant contains a compound called chamazulene, which is responsible for triggering an allergic response in some individuals.

Additionally, the plant's leaves, flowers, and seeds contain allergenic proteins that can cause skin irritation, itching, and other symptoms of an allergic reaction when they come into contact with the skin or are ingested.

2. Causes kidney damage

Achillea millefolium induces digestive issues in some individuals.

This is due to its ability to alter the natural balance of gut bacteria and increase stomach acid production. The herb's bitter compounds can irritate the stomach lining, leading to symptoms such as bloating, cramps, and diarrhea.

Additionally, Achillea millefolium's antispasmodic properties can slow down digestion, causing discomfort and pain in the abdominal area.

3. Causes kidney damage

Achillea millefolium triggers dizziness spells due to its ability to affect blood pressure and heart rate.

The herb's bioactive compounds, such as sesquiterpenes and flavonoids, may cause a sudden drop in blood pressure, leading to lightheadedness and dizziness.

Additionally, yarrow's stimulatory effects on the nervous system can increase heart rate and cardiac output, further exacerbating these symptoms.

4. Causes kidney damage

Achillea millefolium increases bleeding risk due to its ability to thin the blood and reduce platelet aggregation.

The herb's flavonoids and polyacetylenes, such as achillin and santonin, are responsible for this effect.

These compounds can prolong bleeding time, potentially leading to increased risk of bleeding in individuals taking anticoagulant medications or undergoing surgery.

5. Causes kidney damage

Achillea millefolium interferes with blood clotting due to its ability to thin the blood and reduce platelet aggregation.

This is attributed to the presence of flavonoids, coumarins, and other bioactive compounds that inhibit the production of thromboxane A2, a potent vasoconstrictor involved in blood coagulation.

Additionally, yarrow's anticoagulant properties may be enhanced by its ability to reduce fibrinogen levels, further contributing to its inhibitory effects on blood clotting.

6. Causes kidney damage

Achillea millefolium enhances sedative effects.

The plant's flavonoids and sesquiterpenes compounds have been shown to interact with the brain's neurotransmitters, such as GABA, which can lead to a decrease in anxiety and stress levels. Additionally, Achillea millefolium contains coumarins, which are known to exhibit sedative properties, contributing to its potential for enhancing the effects of sedatives.

As a result, individuals using Achillea millefolium may experience increased drowsiness or relaxation.

7. Causes kidney damage

Achillea millefolium amplifies antidepressant properties by enhancing serotonin levels in the brain.

This is due to its ability to increase GABA (gamma-aminobutyric acid) production, a neurotransmitter that helps regulate mood and emotional response.

Additionally, Achillea millefolium has been found to possess anxiolytic and sedative effects, further contributing to its antidepressant properties by promoting relaxation and reducing anxiety.

8. Causes kidney damage

Achillea millefolium interacts with anticoagulants.

The herb's ability to thin blood and promote bleeding can exacerbate the effects of anticoagulant medications, increasing the risk of bleeding complications.

This is due to the presence of bioactive compounds such as flavonoids and phenolic acids in Achillea millefolium, which have antiplatelet and vasodilatory properties that can further reduce blood clotting.

9. Causes kidney damage

Achillea millefolium reduces blood pressure by its ability to relax and dilate blood vessels.

This is due to the presence of flavonoids and volatile oils in the plant, which have a calming effect on the cardiovascular system.

As a result, Achillea millefolium may decrease blood pressure in individuals with hypertension or hypotension, potentially leading to symptoms such as dizziness, lightheadedness, and fainting.

10. Causes kidney damage

Achillea millefolium affects liver function tests.

The flavonoids and volatile oils present in Achillea millefolium may cause changes in liver enzyme levels, potentially leading to elevated transaminase levels. This is due to the herb's ability to stimulate liver metabolism and increase the production of enzymes involved in detoxification processes.

As a result, individuals taking Achillea millefolium may experience abnormal liver function test results.