Zanthoxylum riedelianum
Zanthoxylum riedelianum · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Zanthoxylum riedelianum is a botanical species that has become a subject of significant interest in pharmacological research. Recent investigations have focused on its complex chemical constituents to uncover potential therapeutic applications. Among these findings, the specific preparation known as orbitide[1-8-NαC]-zanriorb A1 has been identified as a notable derivative. Scientific studies have specifically highlighted the cytotoxic activities associated with this compound. Understanding these biological mechanisms provides critical insights into the plant's medicinal potential.
- Synonyms
- Fagara Riedeliana
- Common names
- Not available
- Family
- Rutaceae
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Common Names
Zanthoxylum riedelianum is a plant known by a diverse array of regional names that reflect its cultural significance. It is frequently referred to by the common names Mamica-de-cadela and Mamica-de-porca in various local dialects. Additionally, the species is widely recognized under the name Tembetari, which is often spelled as Tembetarí depending on the linguistic context. Another common variation used to identify this plant is Tembetaíba. This variety of nomenclature highlights the rich botanical heritage associated with the species.
Sources: Catalogue of Life (COL)
Synonyms
Zanthoxylum riedelianum is a botanical species that is frequently identified by its taxonomic synonym, Fagara riedeliana. While these two names may appear different to the casual observer, they refer to the exact same plant within the scientific community. This nomenclatural overlap often occurs as botanical classifications are updated to reflect new genetic understandings. Understanding these relationships is essential for researchers and gardeners who wish to ensure they are studying the correct organism. Consequently, recognizing both names allows for clearer communication across diverse botanical databases.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Zanthoxylum riedelianum is a distinctive species belonging to the vast kingdom Plantae. Within this biological realm, it is specifically classified under the class Equisetopsida. This plant falls into the order Sapindales, showcasing its evolutionary connection to other diverse woody species. It is further organized into the family Rutaceae, a group often known for its aromatic qualities. Ultimately, its precise identity is defined by its membership in the genus Zanthoxylum.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Sapindales |
| Family | Rutaceae |
| Genus | Zanthoxylum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Zanthoxylum riedelianum exhibits a broad and diverse geographical range that spans across multiple continents. In North America, the species is widely distributed throughout various regions of Mexico, including the Central, Gulf, Southeast, and Southwest territories. This extensive presence in Mexico highlights the plant's adaptability to different environmental conditions within the country. Beyond the northern continent, the species also establishes itself in Southern America. Specifically, it can be found growing within the northern reaches of Brazil, marking a significant leap in its natural habitat.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Zanthoxylum riedelianum is a robust, self-supporting species characterized by its distinct tree growth form. This plant can reach impressive proportions within its natural habitat, typically scaling between 20 and 30 meters in height. Its sturdy structure allows it to stand firmly as a prominent feature of the forest canopy. Understanding these physical dimensions is essential for identifying the species in the wild.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Zanthoxylum riedelianum is a medicinal plant from which the unique orbitide [1-8-NαC]-zanriorb A1 was originally isolated. Research indicates that the natural product extracted from this species exhibits significant cytotoxic activity, specifically against Jurkat leukemia T cells. To further explore these properties, scientists synthesized various alanine-containing analogues to test their biological effects. While these specific synthetic derivatives did not demonstrate the same cytotoxicity as the natural isolate, they showed promising anti-inflammatory potential. This investigation highlights the complex chemical profile of the plant and its potential for developing new therapeutic agents.
Compounds
Conditions
Zanthoxylum riedelianum produces the medicinal compound zanriorb A1, which has demonstrated significant cytotoxic properties. This natural product is specifically noted for its ability to treat Jurkat leukemia T cells through its cytotoxic activity. While researchers successfully synthesized various alanine-containing analogues of this orbitide, these synthetic versions lacked the same cytotoxic efficacy. The inactivity of the synthetic peptides suggests that the original plant material contains specific rotamers or impurities essential for its anti-leukemic effects. Consequently, the relationship between the plant extract and its ability to target Jurkat leukemia T cells remains tied to the unique structure of its naturally isolated components.
Preparations
Zanthoxylum riedelianum serves as the source of the medicinal orbitide[1-8-NαC]-zanriorb A1. This specific compound is isolated from the plant to be studied for its unique chemical structure and biological properties. Researchers investigated its synthesis through both solution-phase macrocyclization and on-resin solid-phase macrocyclization methods. While the natural product isolated from the plant shows significant cytotoxicity, synthetic versions were explored to develop more effective alanine-containing analogues. These derivatives aim to harness the plant's potential by focusing on anti-inflammatory activities such as inhibiting nitric oxide production.