Climbing Orange

Zanthoxylum asiaticum · Accepted scientific name

Scientific literature: Moderate (103 studies) · ★★★☆☆

Climbing Orange, scientifically known as Zanthoxylum asiaticum, is a versatile medicinal climber native to Southeast Asia. Renowned for its aromatic, citrus-like leaves, it is widely used in traditional medicine to treat digestive ailments, respiratory issues, and skin infections. This potent botanical serves as a vital natural remedy worldwide.

Family
Rutaceae
Native range
Africa
Parts used
Root · Fruit
Common names
Climbing Orange · Climbing-Orange · 4 more
Scientific synonyms
Toddalia Willdenowii · Scopolia Angustifolia · 25 more

Names

Common Names

Scientific Names

Accepted name

Zanthoxylum asiaticum

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Sapindales and the family Rutaceae. It is specifically identified by the genus Zanthoxylum.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Sapindales WCVP
Family Rutaceae WCVP
Genus Zanthoxylum WCVP

Distribution

This plant exhibits a specific geographical distribution concentrated within the African continent. In West-Central Tropical Africa, its presence is documented in Burundi, Rwanda, and the Democratic Republic of the Congo. Moving toward the northeast, the species is also found within the tropical regions of Ethiopia. Furthermore, its range extends into the territory of Sudan and South Sudan. Together, these locations define the primary habitat for this medicinal species across Africa.

Region Area Source
West-Central Tropical Africa Burundi WCVP
West-Central Tropical Africa Rwanda WCVP
West-Central Tropical Africa DR Congo WCVP
Northeast Tropical Africa Ethiopia WCVP
Northeast Tropical Africa Sudan-South Sudan WCVP
East Tropical Africa Kenya WCVP
East Tropical Africa Tanzania WCVP
East Tropical Africa Uganda WCVP
South Tropical Africa Malawi WCVP
South Tropical Africa Mozambique WCVP

Plant Parts

This plant, Zanthoxylum asiaticum, possesses various components that are utilized for their medicinal properties. The roots and the specific root bark are often harvested for their bioactive compounds, providing essential therapeutic benefits. In addition to the entire root structure, the leaves are frequently employed in traditional remedies due to their aromatic and healing qualities. Furthermore, the fruits of the plant are also significant, contributing to the diverse range of medicinal applications derived from this species.
Plant Part Sources Consensus
root Phytotherapy research : PTR (and other 6 sources) ★★★☆☆
fruit Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
leaf Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Chemicals

Zanthoxylum asiaticum has 52 reported phytochemicals identified across 8 scientific publications and several other databases. The most consistently reported chemicals include Isopimpinellin, Toddalolactone, Toddanone, Aculeatin, Coumarins.

Chemicals reported in Zanthoxylum asiaticum
Chemical Supporting sources Consensus
Isopimpinellin 4 supporting sources ★★☆☆☆
Toddalolactone 3 supporting sources ★★☆☆☆
Toddanone 3 supporting sources ★★☆☆☆
Aculeatin 2 supporting sources ★☆☆☆☆
Coumarins 2 supporting sources ★☆☆☆☆
Nitidine 2 supporting sources ★☆☆☆☆
Toddaculin 2 supporting sources ★☆☆☆☆
Toddalenone 2 supporting sources ★☆☆☆☆
chelerythrine 2 supporting sources ★☆☆☆☆
(+)-Toddanol 1 supporting sources ★☆☆☆☆

Isopimpinellin

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  3. Analytical biochemistry
  4. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Toddalolactone

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Phytotherapy research : PTR
  3. Analytical biochemistry

Toddanone

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Phytotherapy research : PTR
  3. Pharmacognosy magazine

Aculeatin

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Biochemical and biophysical research communications

Coumarins

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  2. Phytotherapy research : PTR

Nitidine

  1. Pharmacognosy magazine
  2. Antimicrobial agents and chemotherapy

Toddaculin

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. PloS one

Toddalenone

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Pharmacognosy magazine

chelerythrine

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Analytical biochemistry

(+)-Toddanol

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Activities

Zanthoxylum asiaticum has 10 reported activities identified across 8 scientific publications and several other databases. The most consistently reported activities include Antidiabetic, Antifungal, Antimalarial, Antioxidant, Analgesic.

Most Reported Activities

Activity Sources Consensus
Antidiabetic Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
Antifungal Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
Antimalarial Antimicrobial agents and chemotherapy (and other 2 sources) ★☆☆☆☆
Antioxidant Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
Analgesic Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society (and other 1 sources) ★☆☆☆☆
Antibacterial Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Antimicrobial Food chemistry (and other 1 sources) ★☆☆☆☆
Antinociceptive The Pan African medical journal (and other 1 sources) ★☆☆☆☆
Antiplasmodial Fitoterapia (and other 1 sources) ★☆☆☆☆
Cytotoxic Food chemistry (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
ethanol extract Indian journal of pharmaceutical sciences (and other 2 sources) ★☆☆☆☆
Ethyl acetate extract of the fruits Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Ethyl acetate fraction Phytochemistry (and other 1 sources) ★☆☆☆☆
L/RB Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
RB Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Toddalia asiatica extract Analytical biochemistry (and other 1 sources) ★☆☆☆☆
aqueous extract Indian journal of pharmaceutical sciences (and other 1 sources) ★☆☆☆☆
aqueous extracts Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
callus cultures Pharmacognosy magazine (and other 1 sources) ★☆☆☆☆
chloroform fraction Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆