Climbing Orange
Zanthoxylum asiaticum · Accepted scientific name
Scientific literature: Moderate (103 studies) · ★★★☆☆
Climbing Orange, scientifically known as Zanthoxylum asiaticum, is a versatile medicinal climber native to Southeast Asia. Renowned for its aromatic, citrus-like leaves, it is widely used in traditional medicine to treat digestive ailments, respiratory issues, and skin infections. This potent botanical serves as a vital natural remedy worldwide.
Names
Common Names
- Climbing Orange
- Climbing-Orange
- Cockspur Orange
- Cockspur-Orange
- Walking-Stick Climber
- orange climber
Scientific Names
Accepted name
Zanthoxylum asiaticumSynonyms
- Toddalia willdenowii
- Scopolia angustifolia
- Toddalia micrantha
- Toddalia nitida
- Aralia labordei
- Toddalia ambigua
- Toddalia asiatica var. obtusifolia
- Toddalia asiatica
- Cranzia schmidelioides
- Cranzia micrantha
- Cranzia asiatica
- Toddalia asiatica var. floribunda
- Scopolia rubicaulis
- Toddalia asiatica var. gracilis
- Cranzia nitida
- Cranzia willdenowii
- Paullinia asiatica
- Rubentia angustifolia
- Limonia oligandra
- Toddalia tonkinensis
- Toddalia angustifolia
- Toddalia effusa
- Toddalia rubicaulis
- Toddalia schmidelioides
- Toddalia floribunda
- Scopolia micracantha
- Scopolia nitida
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Sapindales and the family Rutaceae. It is specifically identified by the genus Zanthoxylum.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Sapindales | WCVP |
| Family | Rutaceae | WCVP |
| Genus | Zanthoxylum | WCVP |
Distribution
This plant exhibits a specific geographical distribution concentrated within the African continent. In West-Central Tropical Africa, its presence is documented in Burundi, Rwanda, and the Democratic Republic of the Congo. Moving toward the northeast, the species is also found within the tropical regions of Ethiopia. Furthermore, its range extends into the territory of Sudan and South Sudan. Together, these locations define the primary habitat for this medicinal species across Africa.
| Region | Area | Source |
|---|---|---|
| West-Central Tropical Africa | Burundi | WCVP |
| West-Central Tropical Africa | Rwanda | WCVP |
| West-Central Tropical Africa | DR Congo | WCVP |
| Northeast Tropical Africa | Ethiopia | WCVP |
| Northeast Tropical Africa | Sudan-South Sudan | WCVP |
| East Tropical Africa | Kenya | WCVP |
| East Tropical Africa | Tanzania | WCVP |
| East Tropical Africa | Uganda | WCVP |
| South Tropical Africa | Malawi | WCVP |
| South Tropical Africa | Mozambique | WCVP |
Plant Parts
This plant, Zanthoxylum asiaticum, possesses various components that are utilized for their medicinal properties. The roots and the specific root bark are often harvested for their bioactive compounds, providing essential therapeutic benefits. In addition to the entire root structure, the leaves are frequently employed in traditional remedies due to their aromatic and healing qualities. Furthermore, the fruits of the plant are also significant, contributing to the diverse range of medicinal applications derived from this species.| Plant Part | Sources | Consensus |
|---|---|---|
| root | Phytotherapy research : PTR (and other 6 sources) | ★★★☆☆ |
| fruit | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| leaf | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Zanthoxylum asiaticum has 52 reported phytochemicals identified across 8 scientific publications and several other databases. The most consistently reported chemicals include Isopimpinellin, Toddalolactone, Toddanone, Aculeatin, Coumarins.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Isopimpinellin | 4 supporting sources | ★★☆☆☆ |
| Toddalolactone | 3 supporting sources | ★★☆☆☆ |
| Toddanone | 3 supporting sources | ★★☆☆☆ |
| Aculeatin | 2 supporting sources | ★☆☆☆☆ |
| Coumarins | 2 supporting sources | ★☆☆☆☆ |
| Nitidine | 2 supporting sources | ★☆☆☆☆ |
| Toddaculin | 2 supporting sources | ★☆☆☆☆ |
| Toddalenone | 2 supporting sources | ★☆☆☆☆ |
| chelerythrine | 2 supporting sources | ★☆☆☆☆ |
| (+)-Toddanol | 1 supporting sources | ★☆☆☆☆ |
Isopimpinellin
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Analytical biochemistry
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Toddalolactone
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Phytotherapy research : PTR
- Analytical biochemistry
Toddanone
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Phytotherapy research : PTR
- Pharmacognosy magazine
Aculeatin
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Biochemical and biophysical research communications
Coumarins
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
- Phytotherapy research : PTR
Nitidine
- Pharmacognosy magazine
- Antimicrobial agents and chemotherapy
Toddaculin
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- PloS one
Toddalenone
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Pharmacognosy magazine
chelerythrine
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Analytical biochemistry
(+)-Toddanol
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Activities
Zanthoxylum asiaticum has 10 reported activities identified across 8 scientific publications and several other databases. The most consistently reported activities include Antidiabetic, Antifungal, Antimalarial, Antioxidant, Analgesic.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antidiabetic | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| Antifungal | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| Antimalarial | Antimicrobial agents and chemotherapy (and other 2 sources) | ★☆☆☆☆ |
| Antioxidant | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| Analgesic | Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society (and other 1 sources) | ★☆☆☆☆ |
| Antibacterial | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Antimicrobial | Food chemistry (and other 1 sources) | ★☆☆☆☆ |
| Antinociceptive | The Pan African medical journal (and other 1 sources) | ★☆☆☆☆ |
| Antiplasmodial | Fitoterapia (and other 1 sources) | ★☆☆☆☆ |
| Cytotoxic | Food chemistry (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| ethanol extract | Indian journal of pharmaceutical sciences (and other 2 sources) | ★☆☆☆☆ |
| Ethyl acetate extract of the fruits | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Ethyl acetate fraction | Phytochemistry (and other 1 sources) | ★☆☆☆☆ |
| L/RB | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| RB | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Toddalia asiatica extract | Analytical biochemistry (and other 1 sources) | ★☆☆☆☆ |
| aqueous extract | Indian journal of pharmaceutical sciences (and other 1 sources) | ★☆☆☆☆ |
| aqueous extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| callus cultures | Pharmacognosy magazine (and other 1 sources) | ★☆☆☆☆ |
| chloroform fraction | Phytotherapy research : PTR (and other 1 sources) | ★☆☆☆☆ |