milk bush

Xysmalobium undulatum · Accepted scientific name

Scientific literature: Very Sparse (12 studies) · ★☆☆☆☆

Milk bush, scientifically known as Xysmalobium undulatum, is a versatile medicinal plant prized for its unique healing properties. Often found in tropical regions, this botanical treasure is utilized in traditional medicine to treat various ailments, offering natural therapeutic benefits through its potent bioactive compounds and distinctive wavy-leaved foliage.

Family
Apocynaceae
Native range
Africa
Parts used
Root
Common names
Not available
Scientific synonyms
Not available

Names and Synonyms

Scientific Names

Accepted name

Xysmalobium undulatum

Regional and Traditional Names

German:

  • Uzara

Sources: Wikidata

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Gentianales and the family Apocynaceae. It is specifically identified by the genus Xysmalobium and the species Xysmalobium undulatum.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Gentianales
Family Apocynaceae
Genus Xysmalobium

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a broad geographical distribution across several regions of the African continent. In Northeast Tropical Africa, it can be found growing within the borders of Ethiopia. Its presence extends into East Tropical Africa, where it is documented in Kenya, Tanzania, and Uganda. Furthermore, the species reaches into the southern reaches of the continent. Specifically, it is also located within the territory of Angola in South Tropical Africa.

Region Area
Northeast Tropical Africa Ethiopia
East Tropical Africa Kenya
East Tropical Africa Tanzania
East Tropical Africa Uganda
South Tropical Africa Angola
South Tropical Africa Malawi
South Tropical Africa Mozambique
South Tropical Africa Zambia
South Tropical Africa Zimbabwe
Southern Africa Botswana

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Xysmalobium undulatum is characterized by its broad vertical distribution across diverse topographical gradients, allowing it to occupy a wide variety of montane and lowland niches. This species exhibits significant adaptability to varying altitudinal pressures, thriving within an elevational range that spans from a minimum of 80 m AMSL to a maximum of 2000 m AMSL. This extensive altitudinal breadth suggests that the plant can tolerate a diverse spectrum of environmental conditions, including variations in temperature, atmospheric pressure, and moisture availability associated with different mountain zones. Such a wide distribution indicates that Xysmalobium undulatum is capable of establishing itself in both tropical lowland environments and higher-altitude montane ecosystems.

Elevational range max:
2000 m AMSL
Elevational range min:
80 m AMSL

Life history

The life history of Xysmalobium undulatum is characterized by its status as a perennial species, allowing the plant to persist through multiple growing seasons rather than completing its cycle within a single year. This perennial lifecycle enables the organism to establish a stable presence within its ecological niche, undergoing seasonal developmental phases that support long-term survival and repeated reproductive efforts. Unlike annuals or biennials that face a complete lifecycle completion after one or two years, this plant maintains its vegetative structures over extended periods, contributing to its sustained biological presence in its natural habitat.

Lifecycle :
perennial

Morphology

The morphology of Xysmalobium undulatum is characterized by its growth form as a non-woody herb, presenting a stature that typically ranges from a minimum height of 0.5 m to a maximum of 1.79 m. As a self-supporting plant, it does not function as a climber and maintains an independent life cycle, acting as a non-parasitic organism. Its ecological habitat and positioning are primarily terrestrial, though it exhibits a versatile environmental adaptation across aquatic, semiaquatic, and terrestrial zones.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
herb
Parasite :
independent
Plant height max:
1.79 m
Plant height min:
0.5 m
Woodiness :
non-woody

Reproduction

The reproduction of Xysmalobium undulatum is characterized by a highly consistent seed production profile, exhibiting no variance in individual seed weight. The seed mass is uniform across the sampled population, with a mean mass of 0.0065 g. This stability is reflected in the maximum and minimum recorded values, which both strictly equal 0.0065 g, indicating a precise and standardized reproductive output regarding the physical dimensions of its progeny.

Seed mass mean:
0.0065 g

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Xysmalobium undulatum has 1 reported plant parts identified across 1 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root.

Plant parts reported in Xysmalobium undulatum
Plant part Supporting sources Consensus
Root 1 supporting sources ★☆☆☆☆

Root

  1. International journal of clinical pharmacology and therapeutics

Chemicals

Xysmalobium undulatum has 4 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include Uzarin, Allouzarigenin, Uzarigenin, Xysmalorin.

Chemicals reported in Xysmalobium undulatum
Chemical Supporting sources Consensus
Uzarin 2 supporting sources ★☆☆☆☆
Allouzarigenin 1 supporting sources ★☆☆☆☆
Uzarigenin 1 supporting sources ★☆☆☆☆
Xysmalorin 1 supporting sources ★☆☆☆☆

Uzarin

  1. Pharmaceutical biology
  2. South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges

Allouzarigenin

  1. International journal of clinical pharmacology and therapeutics

Uzarigenin

  1. International journal of clinical pharmacology and therapeutics

Xysmalorin

  1. International journal of clinical pharmacology and therapeutics

Activities

Xysmalobium undulatum has 2 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include Hepatotoxic, Spasmolytic.

Activities reported in Xysmalobium undulatum
Activity Supporting sources Consensus
Hepatotoxic 1 supporting sources ★☆☆☆☆
Spasmolytic 1 supporting sources ★☆☆☆☆

Hepatotoxic

  1. Journal of ethnopharmacology

Spasmolytic

  1. Journal of ethnopharmacology

Conditions

Xysmalobium undulatum has 3 reported investigations on conditions identified across 1 scientific publications and several other databases. The most consistently reported conditions include Alzheimer's disease, colorectal cancer, depression.

Conditions investigated for Xysmalobium undulatum
Condition Supporting sources Consensus
Alzheimer's disease 1 supporting sources ★☆☆☆☆
Colorectal cancer 1 supporting sources ★☆☆☆☆
Depression 1 supporting sources ★☆☆☆☆

Alzheimer's disease

  1. Journal of ethnopharmacology

Colorectal cancer

  1. Molecules (Basel, Switzerland)

Depression

  1. Journal of ethnopharmacology

Preparations

Xysmalobium undulatum has 7 reported preparations identified across 1 scientific publications and several other databases. The most consistently reported preparations include Uzara extract, Uzara product, Uzara® Lösung N, crude X. undulatum aqueous extract, crude aqueous extracts.

Preparations reported for Xysmalobium undulatum
Preparation Supporting sources Consensus
Uzara extract 1 supporting sources ★☆☆☆☆
Uzara product 1 supporting sources ★☆☆☆☆
Uzara® lösung n 1 supporting sources ★☆☆☆☆
Crude x. undulatum aqueous extract 1 supporting sources ★☆☆☆☆
Crude aqueous extracts 1 supporting sources ★☆☆☆☆
Ethanolic extract of the whole plant 1 supporting sources ★☆☆☆☆
Uzara root extract 1 supporting sources ★☆☆☆☆

Uzara extract

  1. International journal of clinical pharmacology and therapeutics

Uzara product

  1. International journal of clinical pharmacology and therapeutics

Uzara® lösung n

  1. International journal of clinical pharmacology and therapeutics

Crude x. undulatum aqueous extract

  1. Journal of ethnopharmacology

Crude aqueous extracts

  1. Molecules (Basel, Switzerland)

Ethanolic extract of the whole plant

  1. Journal of ethnopharmacology

Uzara root extract

  1. International journal of clinical pharmacology and therapeutics