Indian rennet
Withania coagulans · Accepted scientific name
Scientific literature: Extensive (151 studies) · ★★★★☆
Indian rennet, scientifically known as Withania coagulans, is a versatile medicinal plant native to the Indian subcontinent. Renowned for its unique coagulating properties, it is traditionally used in Ayurvedic medicine to treat various ailments. This potent herb offers significant therapeutic potential, particularly in managing inflammation and supporting overall wellness.
- Family
- Solanaceae
- Native range
- Asia-Temperate
- Parts used
- Fruit · Leaf
- Common names
- Indian Rennet · Panirband · 1 more
- Scientific synonyms
- Puneeria Coagulans
Names
Common Names
- Indian rennet
- panirband
- vegetable rennet
Scientific Names
Accepted name
Withania coagulansSynonyms
- Puneeria coagulans
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and class Equisetopsida. Following the subclass Magnoliidae, it is placed under the order Solanales and the family Solanaceae. Finally, it is categorized under the genus Withania, specifically as the species Withania coagulans.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Solanales | WCVP |
| Family | Solanaceae | WCVP |
| Genus | Withania | WCVP |
Distribution
This plant exhibits a wide geographical distribution spanning several key regions across Asia. In Western Asia, its presence is noted within the territories of Afghanistan and Iran. It can also be found extending into the Arabian Peninsula, specifically in Oman. Moving towards the Indian Subcontinent, the species is widely distributed throughout India. Furthermore, its range extends northward into the neighboring country of Nepal.
| Region | Area | Source |
|---|---|---|
| Western Asia | Afghanistan | WCVP |
| Western Asia | Iran | WCVP |
| Arabian Peninsula | Oman | WCVP |
| Indian Subcontinent | India | WCVP |
| Indian Subcontinent | Nepal | WCVP |
| Indian Subcontinent | Pakistan | WCVP |
Plant Parts
This plant, Withania coagulans, is a versatile medicinal herb where various components are utilized for their therapeutic properties. The whole plant is often processed to extract its bioactive compounds, though specific parts are frequently singled out for concentrated use. The leaves are highly valued for their pharmacological potential, while the stems provide the structural support necessary for the plant's growth. Additionally, the reproductive structures are significant, as the fruit serves as a key part of the plant's life cycle, with both the individual fruit and the collective fruits being studied for their unique chemical constituents.| Plant Part | Sources | Consensus |
|---|---|---|
| fruit | Pakistan journal of pharmaceutical sciences (and other 6 sources) | ★★★☆☆ |
| leaf | Gene (and other 3 sources) | ★★☆☆☆ |
| root | Avicenna journal of phytomedicine (and other 2 sources) | ★☆☆☆☆ |
| stem | Applied biochemistry and biotechnology (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Withania coagulans has 39 reported phytochemicals identified across 12 scientific publications and several other databases. The most consistently reported chemicals include Withanolides, Withaferin A, withanolide, (17S,20S,22R)-14alpha,15alpha,17beta,20beta-tetrahydroxy-1-oxowitha-2,5,24-trienolide, 5-hydroxy tryptophan.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Withanolides | 8 supporting sources | ★★★★☆ |
| Withaferin A | 2 supporting sources | ★☆☆☆☆ |
| withanolide | 2 supporting sources | ★☆☆☆☆ |
| (17S,20S,22R)-14alpha,15alpha,17beta,20beta-tetrahydroxy-1-oxowitha-2,5,24-trienolide | 1 supporting sources | ★☆☆☆☆ |
| 5-hydroxy tryptophan | 1 supporting sources | ★☆☆☆☆ |
| 6-Benzyladenine | 1 supporting sources | ★☆☆☆☆ |
| Ajugin E | 1 supporting sources | ★☆☆☆☆ |
| Caryophyllene oxide | 1 supporting sources | ★☆☆☆☆ |
| Coagulin E | 1 supporting sources | ★☆☆☆☆ |
| Coagulin L | 1 supporting sources | ★☆☆☆☆ |
Withanolides
- BMC plant biology
- Methods in molecular biology (Clifton, N.J.)
- Protoplasma
- Pakistan journal of pharmaceutical sciences
- Molecules (Basel, Switzerland)
View 3 additional sources
- Biology
- Applied biochemistry and biotechnology
- Materials science & engineering. C, Materials for biological applications
Withaferin A
- Steroids
- Natural product communications
withanolide
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- Applied biochemistry and biotechnology
(17S,20S,22R)-14alpha,15alpha,17beta,20beta-tetrahydroxy-1-oxowitha-2,5,24-trienolide
- Bioorganic & medicinal chemistry letters
5-hydroxy tryptophan
- Protoplasma
6-Benzyladenine
- Pakistan journal of biological sciences : PJBS
Ajugin E
- Biology
Caryophyllene oxide
- PloS one
Coagulin E
- Biology
Coagulin L
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Activities
Withania coagulans has 18 reported activities identified across 12 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antihyperglycemic, Antimicrobial, Hepatoprotective, Antibacterial.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antioxidant | Nephro-urology monthly (and other 4 sources) | ★★☆☆☆ |
| Antihyperglycemic | Nephro-urology monthly (and other 3 sources) | ★★☆☆☆ |
| Antimicrobial | PloS one (and other 3 sources) | ★★☆☆☆ |
| Hepatoprotective | Pakistan journal of pharmaceutical sciences (and other 3 sources) | ★★☆☆☆ |
| Antibacterial | PloS one (and other 2 sources) | ★☆☆☆☆ |
| Cardiovascular | The Journal of pharmacy and pharmacology (and other 2 sources) | ★☆☆☆☆ |
| Diuretic | Molecules (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
| Hypoglycemic | Journal of pharmacy & bioallied sciences (and other 2 sources) | ★☆☆☆☆ |
| Anticancer | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
| Antidepressant | Evidence-based complementary and alternative medicine : eCAM (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Withania coagulans has 44 reported medicinal uses identified across 12 scientific publications and several other databases. The most consistently reported uses include asthma, diabetes mellitus, insomnia, Antidiabetic, Benign Prostatic Hyperplasia.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| asthma | Acta poloniae pharmaceutica (and other 2 sources) | ★☆☆☆☆ |
| diabetes mellitus | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| insomnia | Molecules (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
| Antidiabetic | ACS omega (and other 1 sources) | ★☆☆☆☆ |
| Benign Prostatic Hyperplasia | Nephro-urology monthly (and other 1 sources) | ★☆☆☆☆ |
| Diabetes mellitus | Journal of pharmacy & bioallied sciences (and other 1 sources) | ★☆☆☆☆ |
| Escherichia coli | PloS one (and other 1 sources) | ★☆☆☆☆ |
| Hypercholesterolemia | Pakistan journal of pharmaceutical sciences (and other 1 sources) | ★☆☆☆☆ |
| Leishmania major | Chemical & pharmaceutical bulletin (and other 1 sources) | ★☆☆☆☆ |
| Parkinson's disease | Metabolic brain disease (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| crude extracts | Evidence-based complementary and alternative medicine : eCAM (and other 2 sources) | ★☆☆☆☆ |
| extract | Nephro-urology monthly (and other 2 sources) | ★☆☆☆☆ |
| Methanolic extract | Journal of pharmacy & bioallied sciences (and other 1 sources) | ★☆☆☆☆ |
| Methanolic extract of plant material | Steroids (and other 1 sources) | ★☆☆☆☆ |
| Withania Coagulans Extract (WCE) | Avicenna journal of phytomedicine (and other 1 sources) | ★☆☆☆☆ |
| Withania coagulans extract | Steroids (and other 1 sources) | ★☆☆☆☆ |
| aqueous extract | ACS omega (and other 1 sources) | ★☆☆☆☆ |
| aqueous extracts | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
| aqueous methanolic fruits (AqMFEt) extracts | Pakistan journal of pharmaceutical sciences (and other 1 sources) | ★☆☆☆☆ |
| aqueous stem extract | PloS one (and other 1 sources) | ★☆☆☆☆ |