Common Grape Vine

Vitis vinifera · Accepted scientific name

Scientific literature: Very Extensive (1756 studies) · ★★★★★

Common Grape Vine, scientifically known as Vitis vinifera, is a versatile medicinal and nutritional powerhouse. Renowned for its antioxidant-rich skins and seeds, it supports cardiovascular health, combats inflammation, and promotes skin vitality. Beyond its culinary fame, this ancient vine offers significant therapeutic benefits through its potent polyphenolic compounds.

Family
Vitaceae
Native range
Europe
Parts used
Seed · Fruit
Common names
Grapevine · Vine · 8 more
Scientific synonyms
Vitis Vinifera Subsp. Sylvestris · Vitis Vinifera Var. Sylvestris · 140 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Vitis vinifera

Synonyms

Regional and Traditional Names

Spanish:

  • Tronchos
  • Pámpano
  • Vid común
  • Parrena
  • Parreña
  • Vid silvestre
  • Viduño
  • Meseguera
  • Pámpanos
  • Viduno
  • Vid cultivada
  • Vid comun
  • Orquillas
  • Vidueno
  • Pampano
  • Parrucha
  • Parriza
  • Valencín duro
  • Parra de uvas
  • Parra bravía
  • Pampana
  • Viña roja
  • Merceguera
  • Uvillas
  • Valencín tierno
  • Pamparas
  • Parra cultivada
  • Vidueño
  • Pámparas
  • Valencin duro
  • Pampanos
  • Pampanas
  • Valencin tierno
  • Parra bravia
  • Pámpana
  • Pámpanas
  • Vina roja
  • vid
  • viña

German:

  • Weinrebe
  • Echte Weinrebe
  • Rebe
  • echter Weinstock
  • Kultur-Weinrebe
  • Weinrebe
  • Europaeische Weinrebe

French:

  • vigne européenne
  • vigne cultivée
  • vigne américaine
  • vigne rouge
  • cépage
  • Lambrusque
  • Vigne Sauvage
  • vigne
  • vigne cultivée
  • Lambrusque
  • Vigne Sauvage
  • Vigne d'Europe

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Vitales and family Vitaceae, it is classified under the genus Vitis. Its specific scientific name is Vitis vinifera.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Vitales
Family Vitaceae
Genus Vitis

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific presence across various regions within Middle Europe. In the western part of this area, its distribution includes Belgium. Moving toward the central territories, it can be found growing in Germany. The plant also extends its reach into Austria and Hungary. Finally, its geographical range covers the combined regions of Czechia and Slovakia.

Region Area
Middle Europe Austria
Middle Europe Belgium
Middle Europe Czechia-Slovakia
Middle Europe Germany
Middle Europe Hungary
Middle Europe Poland
Middle Europe Switzerland
Southwestern Europe Baleares
Southwestern Europe Corse
Southwestern Europe France

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Vitis vinifera is characterized by its adaptability to a wide range of altitudinal gradients, typically thriving from sea level up to a maximum elevation of 2200 m AMSL. Primarily found in habitats that are cultivated by humans, the species also demonstrates a capacity for naturalization, as it is sometimes locally escaped into wilder environments.

Elevational range max:
2200 m AMSL
Elevational range min:
0 m AMSL
Habitat :
cultivated, sometimes locally escaped

Life history

The life history of Vitis vinifera is characterized by its nature as a perennial plant, allowing it to persist through multiple growing seasons. As a phanerophyte, it develops woody stems that elevate its photosynthetic organs above the ground, providing a robust structural framework for climbing or sprawling. This life form is further specified by its phanerophyte classification, which supports its long-term survival and development of complex vascular systems. Additionally, the species exhibits deciduousness, shedding its foliage annually in response to seasonal changes, a process that facilitates dormancy during unfavorable environmental conditions.

Deciduousness :
deciduous
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Vitis vinifera is characterized by its woody structure and its growth habit as an obligatory climbing vine. As a terrestrial plant, it does not function as an epiphyte or a parasite, maintaining an independent existence. The plant exhibits a scandent shoot orientation, allowing it to ascend through various supports. Although categorized under shrub-like growth forms in certain contexts, it primarily functions as a woody climber with a significant vertical reach; its height is highly variable, ranging from a minimum of 2 meters to a maximum of 30 meters, with a mean plant height of approximately 12.5 meters.

Aquatic :
terrestrial
Climber :
vine
Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
shrub
Parasite :
independent
Plant height max:
30 m
Plant height mean:
12.5 m
Plant height min:
2 m
Shoot orientation :
scandent
Woodiness :
woody

Physiology

The physiology of Vitis vinifera is characterized by a C3 photosynthetic pathway, which dictates its carbon fixation processes and metabolic efficiency. As a non-carnivorous species, it relies on traditional nutrient uptake through its root system and does not possess the ability to fix nitrogen. The plant's foliar morphology is defined by lobed leaf forms that exhibit significant dimensional variation; the leaves typically maintain a mean length of 12.5 cm (ranging from a minimum of 5 cm to a maximum of 18 cm) and a mean width of 11 cm (ranging from a minimum of 5 cm to a maximum of 18 cm), resulting in a mean leaf size of approximately 143.90 cm². These morphological traits are further reflected in its specific leaf area (SLA), which maintains a mean value of 247.1 cm²/g, indicating the structural relationship between the leaf's biomass and its surface area for gas exchange and light interception.

Carnivory :
non-carnivorous
Leaf form :
lobed
Leaf length max:
18 cm
Leaf length mean:
12.5 cm
Leaf length min:
5 cm
Leaf size mean:
143.90125 cm²
Leaf width max:
18 cm
Leaf width mean:
11 cm
Leaf width min:
5 cm
Nitrogen fixer :
no
Photosynthetic pathway :
C3
Specific Leaf Area (SLA) mean:
247.1 cm²/g

Reproduction

The reproduction of Vitis vinifera is characterized by a biotic pollination process primarily driven by insects. The flowering period typically commences in April and extends through June, featuring small green flowers that range in length from 0.5 cm to 0.55 cm. These flowers are arranged in paniculate inflorescences, which vary in length from a minimum of 0.1 m to a maximum of 0.2 m. While self-fertilization is present, the plant relies on insect-mediated pollination to facilitate its reproductive cycle. Following successful fertilization, the plant develops fleshy, indehiscent fruit categorized as a berry, which exhibits a blue coloration. These berries typically possess a mean length of 1.38 cm (ranging from 0.6 cm to 2.5 cm) and a mean width of approximately 1.14 cm (ranging from 1.5 cm to 2 cm). Each fruit contains between 1 and 10 seeds, with an average seed mass of 0.0255 g (ranging from 0.018 g to 0.043 g) and a consistent seed volume of 24 mm³. The dispersal of the species is achieved through a zoochorous syndrome, specifically endozoochory, where seeds are dispersed via the digestive tracts of animals. Asexual reproduction is absent in this species.

Dehiscence :
indehiscent
Dispersal syndrome :
zoochorous
Dispersal syndrome :
endozoochorous
Flower colour :
green
Flower length max:
0.55 cm
Flower length min:
0.5 cm
Flowering time :
Apr
Flowering time :
Jun
Fruit colour :
blue
Fruit dryness :
fleshy
Fruit length max:
2.5 cm
Fruit length mean:
1.38 cm
Fruit length min:
0.6 cm
Fruit type :
berry
Fruit width max:
2 cm
Fruit width mean:
1.14333333333333 cm
Fruit width min:
1.5 cm
Inflorescence :
panicle
Inflorescence length max:
0.2 m
Inflorescence length min:
0.1 m
Pollination syndrome :
insect
Pollination syndrome :
biotic
Reproduction asexual :
absent
Seed mass max:
0.043 g
Seed mass mean:
0.0255 g
Seed mass min:
0.018 g
Seed volume max:
24 mm³
Seeds_per_fruit :
1-10
Self fertilization :
present

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Vitis vinifera has 3 reported plant parts identified across 14 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include seed, fruit, leaf.

Plant parts reported in Vitis vinifera
Plant part Supporting sources Consensus
Seed 7 supporting sources ★★★★☆
Fruit 4 supporting sources ★★☆☆☆
Leaf 3 supporting sources ★★☆☆☆

Seed

  1. Antioxidants (Basel, Switzerland)
  2. African journal of traditional, complementary, and alternative medicines : AJTCAM
  3. Journal of natural products
  4. The American journal of Chinese medicine
  5. Molecules (Basel, Switzerland)
View 2 additional sources
  1. The Korean journal of internal medicine
  2. Arzneimittel-Forschung

Fruit

  1. Antioxidants (Basel, Switzerland)
  2. Journal of ethnopharmacology
  3. Journal of photochemistry and photobiology. B, Biology
  4. Phytotherapy research : PTR

Leaf

  1. Antioxidants (Basel, Switzerland)
  2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  3. Frontiers in pharmacology

Chemicals

Vitis vinifera has 398 reported phytochemicals identified across 14 scientific publications and several other databases. The most consistently reported chemicals include resveratrol, Proanthocyanidins, Gallic acid, polyphenols, CATECHIN.

Chemicals reported in Vitis vinifera
Chemical Supporting sources Consensus
resveratrol 36 supporting sources ★★★★★
Proanthocyanidins 8 supporting sources ★★★★☆
Gallic acid 7 supporting sources ★★★★☆
polyphenols 7 supporting sources ★★★★☆
CATECHIN 6 supporting sources ★★★☆☆
trans-resveratrol 6 supporting sources ★★★☆☆
Epicatechin 5 supporting sources ★★★☆☆
p-coumaric acid 5 supporting sources ★★★☆☆
quercetin 5 supporting sources ★★★☆☆
Piceid 4 supporting sources ★★☆☆☆

resveratrol

  1. Dr. Duke
  2. Phytotherapy research : PTR
  3. Current pharmaceutical biotechnology
  4. Mutation research
  5. Pakistan journal of biological sciences : PJBS
View 31 additional sources
  1. Cardiovascular & hematological agents in medicinal chemistry
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Journal of separation science
  4. BMC complementary medicine and therapies
  5. Food chemistry
  6. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  7. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
  8. Molecules (Basel, Switzerland)
  9. CNS neuroscience & therapeutics
  10. International journal of medicinal mushrooms
  11. Biochemical pharmacology
  12. Plants (Basel, Switzerland)
  13. PloS one
  14. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  15. Chemico-biological interactions
  16. Cytotechnology
  17. Cancer metastasis reviews
  18. Frontiers in nutrition
  19. Journal of photochemistry and photobiology. B, Biology
  20. Annals of the New York Academy of Sciences
  21. Avicenna journal of phytomedicine
  22. Pharmaceuticals (Basel, Switzerland)
  23. Seminars in oncology
  24. BMC plant biology
  25. Toxicology and applied pharmacology
  26. Archives of dermatological research
  27. Journal of cellular physiology
  28. Carcinogenesis
  29. Planta medica
  30. Current medicinal chemistry
  31. Biomedicines

Proanthocyanidins

  1. Biomedicines
  2. Molecules (Basel, Switzerland)
  3. Brain research
  4. Dental materials : official publication of the Academy of Dental Materials
  5. Journal of chromatography. A
View 3 additional sources
  1. Research communications in molecular pathology and pharmacology
  2. Chemistry & biodiversity
  3. Nutrients

Gallic acid

  1. Dr. Duke
  2. Frontiers in nutrition
  3. Pakistan journal of biological sciences : PJBS
  4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  5. Frontiers in pharmacology
View 2 additional sources
  1. BMC plant biology
  2. Medical oncology (Northwood, London, England)

polyphenols

  1. Current pharmaceutical design
  2. Frontiers in nutrition
  3. Fish physiology and biochemistry
  4. Environmental toxicology and pharmacology
  5. Food & function
View 2 additional sources
  1. Foods (Basel, Switzerland)
  2. Antioxidants (Basel, Switzerland)

CATECHIN

  1. Dr. Duke
  2. Frontiers in nutrition
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  4. Food & function
  5. BMC plant biology
View 1 additional sources
  1. Chemistry & biodiversity

trans-resveratrol

  1. Dr. Duke
  2. Archives of biochemistry and biophysics
  3. Frontiers in nutrition
  4. Acta biologica Hungarica
  5. Journal of pharmacological sciences
View 1 additional sources
  1. Nutrition and cancer

Epicatechin

  1. Dr. Duke
  2. Frontiers in nutrition
  3. Pakistan journal of biological sciences : PJBS
  4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  5. Chemistry & biodiversity

p-coumaric acid

  1. Dr. Duke
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Food chemistry
  4. Frontiers in pharmacology
  5. BMC plant biology

quercetin

  1. Dr. Duke
  2. Pakistan journal of biological sciences : PJBS
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  4. Food & function
  5. BMC plant biology

Piceid

  1. Dr. Duke
  2. Food chemistry
  3. The Journal of pharmacy and pharmacology
  4. Journal of photochemistry and photobiology. B, Biology

Activities

Vitis vinifera has 889 reported activities identified across 14 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antibacterial, Antitumor, Antidiabetic.

Activities reported in Vitis vinifera
Activity Supporting sources Consensus
Antioxidant 16 supporting sources ★★★★★
Anticancer 6 supporting sources ★★★☆☆
Antibacterial 5 supporting sources ★★★☆☆
Antitumor 5 supporting sources ★★★☆☆
Antidiabetic 3 supporting sources ★★☆☆☆
Cardioprotective 3 supporting sources ★★☆☆☆
Hepatoprotective 3 supporting sources ★★☆☆☆
Analgesic 2 supporting sources ★☆☆☆☆
Anticarcinogenic 2 supporting sources ★☆☆☆☆
Antihypertensive 2 supporting sources ★☆☆☆☆

Antioxidant

  1. Dr. Duke
  2. Antioxidants (Basel, Switzerland)
  3. International journal of molecular sciences
  4. Journal of food science
  5. Molecules (Basel, Switzerland)
View 11 additional sources
  1. Current topics in medicinal chemistry
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Journal of dietary supplements
  4. Recent patents on drug delivery & formulation
  5. Scientific reports
  6. Molecular and cellular biochemistry
  7. Foods (Basel, Switzerland)
  8. BMC plant biology
  9. The Medical journal of Malaysia
  10. Journal of cellular physiology
  11. The Korean journal of internal medicine

Anticancer

  1. Dr. Duke
  2. Food science & nutrition
  3. BMC complementary medicine and therapies
  4. Translational oncology
  5. Molecules (Basel, Switzerland)
View 1 additional sources
  1. Current topics in medicinal chemistry

Antibacterial

  1. Dr. Duke
  2. Food science & nutrition
  3. Scientific reports
  4. The Medical journal of Malaysia
  5. Evidence-based complementary and alternative medicine : eCAM

Antitumor

  1. Dr. Duke
  2. Foods (Basel, Switzerland)
  3. Journal of cellular physiology
  4. Planta medica
  5. Biomedicines

Antidiabetic

  1. Dr. Duke
  2. Cytotechnology
  3. Journal of cellular physiology

Cardioprotective

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Journal of cellular physiology

Hepatoprotective

  1. Dr. Duke
  2. Molecular and cellular biochemistry
  3. Journal of cellular physiology

Analgesic

  1. Dr. Duke
  2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Anticarcinogenic

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)

Antihypertensive

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)

Conditions

Vitis vinifera has 100 reported investigations on conditions identified across 14 scientific publications and several other databases. The most consistently reported conditions include cancer, oxidative stress, inflammation, Alzheimer's disease, breast cancer.

Conditions investigated for Vitis vinifera
Condition Supporting sources Consensus
Cancer 16 supporting sources ★★★★★
Oxidative stress 8 supporting sources ★★★★☆
Inflammation 6 supporting sources ★★★☆☆
Alzheimer's disease 5 supporting sources ★★★☆☆
Breast cancer 5 supporting sources ★★★☆☆
Cardiovascular disease 4 supporting sources ★★☆☆☆
Stroke 3 supporting sources ★★☆☆☆
Wound 3 supporting sources ★★☆☆☆
Anxiety 2 supporting sources ★☆☆☆☆
Atherosclerosis 2 supporting sources ★☆☆☆☆

Cancer

  1. Food science & nutrition
  2. Archives of biochemistry and biophysics
  3. Cardiovascular & hematological agents in medicinal chemistry
  4. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
  5. Acta biologica Hungarica
View 11 additional sources
  1. PloS one
  2. Cancer metastasis reviews
  3. Frontiers in nutrition
  4. Journal of photochemistry and photobiology. B, Biology
  5. Experimental gerontology
  6. Avicenna journal of phytomedicine
  7. Seminars in oncology
  8. Nutrition and cancer
  9. Medical oncology (Northwood, London, England)
  10. BMC pharmacology & toxicology
  11. Journal of Asian natural products research

Oxidative stress

  1. Iranian Red Crescent medical journal
  2. Antioxidants (Basel, Switzerland)
  3. International journal of molecular sciences
  4. Journal of food science
  5. Pakistan journal of pharmaceutical sciences
View 3 additional sources
  1. Neuroscience letters
  2. Aging
  3. BioFactors (Oxford, England)

Inflammation

  1. International journal of molecular sciences
  2. Journal of food science
  3. Plants (Basel, Switzerland)
  4. Phytotherapy research : PTR
  5. Journal of cardiovascular pharmacology
View 1 additional sources
  1. Biomedicines

Alzheimer's disease

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Pharmacological research
  3. Nutritional neuroscience
  4. Medicina (Kaunas, Lithuania)
  5. Aging

Breast cancer

  1. Food science & nutrition
  2. Planta medica
  3. Mini reviews in medicinal chemistry
  4. Anti-cancer agents in medicinal chemistry
  5. BioFactors (Oxford, England)

Cardiovascular disease

  1. PloS one
  2. Current atherosclerosis reports
  3. Journal of photochemistry and photobiology. B, Biology
  4. Carcinogenesis

Stroke

  1. PloS one
  2. Molecules (Basel, Switzerland)
  3. Journal of medicinal food

Wound

  1. Antioxidants (Basel, Switzerland)
  2. Phytotherapy research : PTR
  3. Archives of dermatological research

Anxiety

  1. Frontiers in nutrition
  2. Biomedicines

Atherosclerosis

  1. Current pharmaceutical biotechnology
  2. Recent patents on cardiovascular drug discovery

Preparations

Vitis vinifera has 34 reported preparations identified across 14 scientific publications and several other databases. The most consistently reported preparations include crude extracts, Ankafeerd Blood Stopper, Ankaferd Blood Stopper, Plant extracts, SFE extracts.

Preparations reported for Vitis vinifera
Preparation Supporting sources Consensus
Crude extracts 2 supporting sources ★☆☆☆☆
Ankafeerd blood stopper 1 supporting sources ★☆☆☆☆
Ankaferd blood stopper 1 supporting sources ★☆☆☆☆
Plant extracts 1 supporting sources ★☆☆☆☆
Sfe extracts 1 supporting sources ★☆☆☆☆
Uae extracts 1 supporting sources ★☆☆☆☆
Vitis vinifera (v. vinifera) oil nanoemulgel 1 supporting sources ★☆☆☆☆
Vitis vinifera grape seed extract 1 supporting sources ★☆☆☆☆
Vitis vinifera seed extract 1 supporting sources ★☆☆☆☆
Alcohol fractions 1 supporting sources ★☆☆☆☆

Crude extracts

  1. Journal of separation science
  2. Planta medica

Ankafeerd blood stopper

  1. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

Ankaferd blood stopper

  1. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Plant extracts

  1. Discover oncology

Sfe extracts

  1. Molecules (Basel, Switzerland)

Uae extracts

  1. Molecules (Basel, Switzerland)

Vitis vinifera (v. vinifera) oil nanoemulgel

  1. BMC complementary medicine and therapies

Vitis vinifera grape seed extract

  1. The Korean journal of internal medicine

Vitis vinifera seed extract

  1. Antioxidants (Basel, Switzerland)

Alcohol fractions

  1. Phytotherapy research : PTR