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Home | Herbs | Vitex Agnus Castus

Updated: 1 20, 2025

Vitex agnus-castus

What is Vitex agnus-castus?

Vitex agnus-castus is a deciduous shrub or small tree, native to the Mediterranean region and parts of Asia.

It belongs to the family Lamiaceae, commonly known as the mint family. The plant grows up to 6 meters tall, with a greyish-brown bark and elliptical-shaped leaves that are 5-15 centimeters long and 2-5 centimeters wide, with an entire margin and a pointed apex. The leaves are opposite, and the plant produces small, fragrant, blue-purple flowers in axillary spikes, which are 5-7 centimeters long and have a tubular corolla with five lobes.

Vitex agnus-castus is a perennial plant, commonly known as Chaste Tree or Monk's Pepper.

What ailments can you heal with this herb?

The most common ailments you can heal with Vitex agnus-castus are menopausal hot flashes and endometriosis, both of which have been shown to benefit from the plant's ability to regulate hormonal imbalances.

Vitex agnus-castus has been proven to reduce symptoms of premenstrual syndrome, including anxiety, and has also been effective in treating polycystic ovary syndrome, which is associated with hormonal imbalance. Additionally, the plant has been found to improve infertility, particularly in women with hormonal imbalances, and has been shown to alleviate symptoms of menopause, such as mood swings and insomnia. Furthermore, Vitex agnus-castus has been used to treat hirsutism, adrenal fatigue, and premenstrual tension, as well as menstrual cramps and libido imbalance.

By regulating hormonal imbalances and alleviating related symptoms, Vitex agnus-castus has also been used to treat depression, adrenal insufficiency, and libido issues.

What are the therapeutic properties this herb?

The main therapeutic properties of Vitex agnus-castus are its antioxidant activity, which is primarily attributed to the presence of flavonoids, helping to protect against oxidative stress and cell damage.

The plant's anti-inflammatory properties, mediated by saponins and volatile oils, contribute to its ability to reduce inflammation and alleviate pain. Vitex agnus-castus also exhibits antispasmodic effects, caused by the action of iridoid glycosides, which help to relax smooth muscles and alleviate cramps. Furthermore, its antimicrobial properties, attributed to the presence of phenolic acids and flavonoids, enable the plant to inhibit the growth of various microorganisms.

Additionally, the anxiolytic effects of Vitex agnus-castus, primarily due to the action of flavonoids and saponins, make it a useful natural remedy for anxiety and stress relief.

What are the medicinal constituents this herb?

The most important healing constituents of Vitex agnus-castus are agnuside, vitexin, iridoid glycosides, quercetin, and kaempferol, which are responsible for its therapeutic effects.

Agnuside, the primary iridoid glycoside, has been shown to possess estrogen-modulating properties, contributing to its use in treating menstrual irregularities and menopausal symptoms. Vitexin, a flavone glycoside, has been found to have neuroprotective and anti-inflammatory activities. Iridoid glycosides, including agnuside, have been demonstrated to exhibit anti-anxiety and antidepressant effects, while quercetin and kaempferol, two flavonoids, have been shown to possess antioxidant and anti-inflammatory properties, further contributing to the plant's therapeutic potential.

These constituents work synergistically to provide the plant's medicinal benefits, supporting its traditional use in treating various gynecological and neurological disorders.

What are the main herbal preparations this herb?

The main herbal preparations of Vitex agnus-castus are standardized extracts in capsules, which typically contain 0.5-1% agnuside and 1-2% aucubin, standardized tinctures, and teas made from dried flowers.

These preparations are used to treat menstrual irregularities, premenstrual syndrome (PMS), and infertility due to their estrogen-modulating properties, which include inhibiting the release of gonadotropin-releasing hormone (GnRH) and reducing prolactin levels. Infusions of the dried flowers can also be used to treat anxiety, insomnia, and restlessness associated with menopause. Suppositories made from the dried flowers are used for local application to treat vaginal dryness and atrophy in postmenopausal women.

Overall, the various preparations of Vitex agnus-castus are used to support the female reproductive system and alleviate symptoms associated with hormonal imbalances.

What are the possible side effects of using this herb improperly?

The possible side effects of using Vitex agnus-castus improperly include causing dizziness due to its potential to interact with certain medications such as blood thinners and anticoagulants by increasing the risk of bleeding, exacerbating menstruation in individuals with pre-existing conditions such as endometriosis or adenomyosis due to its estrogen-modulating effects, and inducing nausea in some people due to the herb's ability to stimulate the release of stomach acid and cause gastrointestinal upset.

Experiencing dizziness and nausea are common side effects of Vitex agnus-castus, particularly when taken in large doses or combined with other medications. These side effects are thought to be caused by the herb's ability to affect the body's hormonal balance and stimulate the nervous system. Additionally, Vitex agnus-castus may worsen menstruation in individuals who are already experiencing heavy or irregular periods due to its potential to stimulate the uterus and increase prostaglandin production.

It is essential to consult with a healthcare professional before using Vitex agnus-castus, especially for individuals with pre-existing medical conditions or those taking medications.