10 Possible Side Effects Of Verbascum Thapsus (Mullein)

Verbascum thapsus has some side effects when used improperly, such as skin irritation, allergic reactions, and interactions with medications like diuretics, ACE inhibitors, and beta blockers.

These effects are caused by the herb's glycosides and saponins, which can be toxic in high concentrations.

For example, if taken internally, these side effects can worsen people's lives by causing kidney damage, increased blood pressure, and heart problems, making it challenging to manage chronic conditions.

This article explains in details the 10 most common side effects of Verbascum thapsus if used imporperly.

1. Provokes anaphylactic shock

Verbascum thapsus causes allergic reactions due to its ability to stimulate an immune response.

The plant's pollen and other allergenic particles can trigger the release of histamine in some individuals, leading to symptoms such as itching, sneezing, runny nose, and watery eyes.

Additionally, the latex sap present in the leaves and stems may cause skin irritation or contact dermatitis in susceptible people, further contributing to the risk of allergic reactions when using Verbascum thapsus.

2. Provokes anaphylactic shock

Verbascum thapsus triggers bronchial constriction due to its ability to release histamine and other chemical mediators from mast cells.

This can lead to the contraction of airway smooth muscle, reducing airflow and increasing wheezing and shortness of breath. Additionally, Verbascum thapsus contains saponins that can stimulate the production of mucus, further exacerbating respiratory symptoms.

As a result, individuals with pre-existing respiratory conditions such as asthma may experience worsening of their symptoms when using Verbascum thapsus.

3. Provokes anaphylactic shock

Verbascum thapsus induces respiratory distress due to the presence of saponins and mucilages in its leaves.

These compounds can cause bronchospasm and constriction of the airways, leading to symptoms such as coughing, wheezing, and shortness of breath. The irritation caused by these chemicals can also stimulate the production of excess mucus, further exacerbating respiratory issues.

As a result, individuals may experience difficulty breathing, especially in cases where they have pre-existing respiratory conditions or are sensitive to the plant's compounds.

4. Provokes anaphylactic shock

Verbascum thapsus aggravates asthma attacks due to its potential to trigger allergic reactions and exacerbate respiratory issues.

The plant's sap contains allergenic compounds that can cause bronchospasm and increased mucus production, leading to wheezing and difficulty breathing in individuals with pre-existing asthmas.

Additionally, Verbascum thapsus may also increase inflammation in the airways, further compromising lung function.

5. Provokes anaphylactic shock

Verbascum thapsus increases heart rate due to its stimulating effects on the cardiovascular system.

The plant contains compounds such as isorhapontigenin and verbascosaponins, which have been shown to increase cardiac output and systolic blood pressure. This can lead to a rapid heartbeat, palpitations, or even arrhythmias in some individuals.

As a result, Verbascum thapsus may not be suitable for people with pre-existing heart conditions or those taking medications that affect the cardiovascular system.

6. Provokes anaphylactic shock

Verbascum thapsus provokes cardiac arrhythmia due to its high concentration of rosmarinic acid and flavonoids.

These compounds can cause a disturbance in the normal rhythm of the heart, leading to abnormal heartbeats and palpitations. The exact mechanism is not fully understood, but it's believed that the phytochemicals interact with ion channels in the heart cells, disrupting the normal electrical conduction.

This potentially serious side effect requires close monitoring to prevent complications.

7. Provokes anaphylactic shock

Verbascum thapsus inhibits platelet aggregation, which can lead to bleeding tendencies.

This side effect occurs due to the plant's ability to interfere with the production of thromboxane A2, a potent aggregator of platelets in the blood.

As a result, the platelets are unable to form clots, increasing the risk of bruising, petechiae, or even hemorrhage.

8. Provokes anaphylactic shock

Verbascum thapsus enhances bleeding risk due to its ability to increase blood flow and thin the blood.

The plant's saponins, flavonoids, and terpenes have a direct effect on platelet aggregation and vasodilation, which can lead to increased bleeding propensity.

Additionally, the herb's antiplatelet activity may interact with anticoagulant medications, further exacerbating this side effect.

9. Provokes anaphylactic shock

Verbascum thapsus suppresses immune system due to its ability to inhibit the production of white blood cells and reduce the activity of natural killer cells.

This is attributed to the presence of flavonoids and terpenoids in the plant, which can interact with immune system components and disrupt their function.

As a result, individuals using Verbascum thapsus may experience weakened immune responses, making them more susceptible to infections.

10. Provokes anaphylactic shock

Verbascum thapsus produces gastrointestinal upset due to its ability to stimulate the digestive system and increase bowel movements.

The saponins present in mullein can cause an irritant effect on the mucous membranes of the stomach and intestines, leading to nausea, diarrhea, or abdominal cramps.

Additionally, the plant's expectorant properties may also contribute to gastrointestinal upset by loosening stool and exacerbating irritable bowel syndrome symptoms.