By Leen Randell
Updated: Oct 20, 2024
What to know about Valeriana officinalis before using it medicinally
Valeriana officinalis, commonly known as valerian, is a medicinal herb that has been traditionally used to alleviate a range of health conditions, including anxiety, insomnia, restlessness, and stress-related disorders.
The main health benefits of valerian include its sedative, anxiolytic, and adaptogenic properties, which help to promote relaxation, reduce stress levels, and improve sleep quality. The herb's therapeutic properties are attributed to its ability to interact with the GABA receptors in the brain, leading to a calming effect and a reduction in anxiety and restlessness. The main bioactive compounds found in valerian include valepotriates, isovaleramide, and valerenic acid, which are responsible for its medicinal properties.
Valerian root is commonly used to make a herbal tea, which is a popular remedy for promoting relaxation and improving sleep quality.
Featured Study:
According to a study published by "Pharmacology, biochemistry, and behavior", Valeriana officinalis has been found to have a significant sedative effect, particularly due to its sesquiterpenes content. The study revealed that the preparation containing primarily sesquiterpenes resulted in 44% of participants reporting perfect sleep and 89% reporting improved sleep. Additionally, this preparation was shown to have no side effects, making it a potentially beneficial remedy for individuals struggling with poor sleep.
The following article explains in detail what are the medicinal uses of Valeriana officinalis, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.
ARTICLE SUMMARY: The table below summarizes the most crucial information about Valeriana officinalis provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.
| Medicinal Aspect | Summary |
|---|---|
| Uses | Insomnia, Anxiety, Muscle spasms, Restlessness, Hypertension, Depression, Digestive issues, Epilepsy, Stress, Menstrual cramps |
| Benefits | Reduces anxiety, Promotes sleep, Relieves insomnia, Eases stress, Improves digestion, Calms nerves, Treats adhd, Relieves menopause, Treats restless, Reduces inflammation |
| Properties | Antimicrobial, Antioxidant, Anti-inflammatory, Anxiolytic, Sedative, Analgesic, Antispasmodic, Hypnotic, Anticonvulsant, Neuroprotective |
| Constituents | Valerenic acid, Valeranone, Valerenal, Phenolic acids, Saponins, Flavonoids, Isovaleric acid, Valtrate, Valerenol, Phenylethylamine |
| Parts | Roots, Flowers, Rhizomes |
| Preparations | Essential oil, Tincture, Capsule, Salve, Tea |
| Side Effects | Experience dizziness, Exhibit sedative effects, Show allergic reactions, Develop liver damage, Exhibit respiratory depression, Experience memory impairment, Display anticholinergic effects, Suffer from cardiovascular issues, Experience gastrointestinal problems, Develop dependence |
| Precaution | Consult a healthcare professional before use, Start with low doses, Monitor blood pressure and heart rate, Avoid during pregnancy and breastfeeding, Interact with sedatives and anxiolytics, Avoid with liver or kidney disease, Do not use with maois, Be cautious with children and elderly, May worsen depression or anxiety, Gradually taper off use when discontinuing |
BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Valeriana officinalis. Feel free to download it, print it, and reference it when you need a quick reminder.
- What are the main medicinal uses of Valeriana officinalis?
- Modern Western Medicine
- Traditional Chinese Medicine
- Ayurvedic Medicine
- Unani Medicine
- Homeopathic Medicine
- What are the primary health benefits of Valeriana officinalis?
- Circulatory System
- Digestive System
- Endocrine System
- Integumentary System
- Lymphatic System
- Musculoskeletal System
- Nervous System
- Reproductive System
- Respiratory System
- Urinary System
- What are the dominant therapeutic properties of Valeriana officinalis?
- What are the major healing constituents of Valeriana officinalis?
- What are the most used parts of Valeriana officinalis in medicine?
- What are the most common medicinal preparations of Valeriana officinalis?
- What are the possible side effects of Valeriana officinalis if used improperly?
- What are the precautions to take before using Valeriana officinalis medicinally?
- Are there scientific studies that prove the medical effectiveness of Valeriana officinalis?
- Related herbs to Valeriana officinalis?
What are the main medicinal uses of Valeriana officinalis?
The main medicinal uses of Valeriana officinalis are treating insomnia by reducing sleep latency through its sedative properties, primarily due to the valerenic acid and valepotriates constituents that inhibit the activity of GABA receptors, thereby promoting relaxation.
Additionally, it is used to alleviate anxiety, restlessness, and nervousness by modulating the activity of neurotransmitters such as serotonin and GABA, which are involved in regulating emotional responses. Valeriana officinalis has also been used to alleviate digestive issues, including gastrointestinal spasms, and muscle spasms, due to its antispasmodic properties, attributed to the valepotriates and isovaleran constituents. Furthermore, it has been used to alleviate menstrual cramps, hypertension, and rheumatism, as well as epilepsy, due to its antispasmodic, sedative, and anti-inflammatory properties, which are primarily attributed to the valepotriates and isovaleran constituents.
The valepotriates and isovaleran constituents in Valeriana officinalis are also responsible for its ability to reduce inflammation and muscle spasms.
The following illustration give a summary of the main medicinal uses of Valeriana officinalis.
The list below provide more details on why Valeriana officinalis is used to alleviate the health conditions mentioned in the illustration above.
- Insomnia: Valeriana officinalis is used for insomnia due to its sedative properties, which help to reduce restlessness and promote relaxation, allowing individuals to fall asleep and stay asleep.
- Anxiety: Valeriana officinalis is used for anxiety because it contains valerenic acid, a compound that has been shown to have anxiolytic effects, helping to reduce anxiety and promote feelings of calmness.
- Muscle Spasms: Valeriana officinalis is used for muscle spasms due to its muscle relaxant properties, which help to reduce muscle tension and spasms, providing relief and relaxation.
- Restlessness: Valeriana officinalis is used for restlessness because it helps to promote relaxation and reduce anxiety, allowing individuals to feel more calm and composed.
- Hypertension: Valeriana officinalis is used for hypertension due to its ability to help lower blood pressure by reducing anxiety and promoting relaxation, thereby reducing the strain on the cardiovascular system.
- Depression: Valeriana officinalis is used for depression as a mild anxiolytic and sedative, helping to improve mood and reduce symptoms of anxiety and insomnia, which are often associated with depression.
- Digestive Issues: Valeriana officinalis is used for digestive issues such as irritable bowel syndrome due to its antispasmodic properties, which help to reduce muscle spasms in the digestive tract and promote relaxation.
- Epilepsy: Valeriana officinalis has been used historically to help reduce the frequency and severity of seizures in individuals with epilepsy, possibly due to its sedative and anticonvulsant properties.
- Stress: Valeriana officinalis is used for stress due to its adaptogenic properties, which help the body to adapt to stress and promote relaxation, reducing feelings of anxiety and tension.
- Menstrual Cramps: Valeriana officinalis is used to help alleviate menstrual cramps due to its antispasmodic properties, which help to reduce muscle spasms and promote relaxation, providing relief from cramping and discomfort.
The table that follows gives an overview of what are the most common health conditions that are treated with Valeriana officinalis, in each of the major medicinal systems.
| Medicinal System | Conditions Treated |
|---|---|
| Modern Western Medicine | Insomnia, Anxiety, Muscle Spasms, Depression, Epilepsy, Restlessness, Migraines, Digestive Issues, Stress, Menopause Symptoms, Restless Leg Syndrome, Hypertension, Menopausal Symptoms, Sleep Disorders, Irritability, Menopause, Menstrual Cramps, Gastrointestinal Issues, Nausea, Rheumatism |
| Traditional Chinese Medicine | Insomnia, Anxiety, Muscle Spasms, Restlessness, Depression, Epilepsy, Hypertension, Menstrual Cramps, Digestive Issues, Stress, Nervousness, Gastrointestinal Issues, Restless Leg Syndrome, Migraines, Nervous Tension, Headaches, Rheumatism, Gastroesophageal Reflux, Migraine, Menopausal Symptoms |
| Ayurvedic Medicine | Anxiety, Insomnia, Muscle Spasms, Restlessness, Digestive Issues, Hypertension, Depression, Epilepsy, Stress, Menstrual Cramps, Nervousness, Migraines, Sleep Disorders, Pms, Menopausal Symptoms, Rheumatism, Panic Attacks, Headache, Irritability, Gastroesophageal Reflux |
| Unani Medicine | Insomnia, Anxiety, Hypertension, Muscle Spasms, Restlessness, Depression, Epilepsy, Stress, Digestive Issues, Migraines, Sleep Disorders, Restless Leg Syndrome, Menstrual Cramps, Menopause Symptoms, Irritability, Sleep Disorder, Nervousness, Rheumatism, Nausea, Tension Headaches |
| Homeopathic Medicine | Insomnia, Anxiety, Muscle Spasms, Restlessness, Digestive Issues, Stress, Nervousness, Restless Leg Syndrome, Depression, Headaches, Menopause Symptoms, Epilepsy, Hypertension, Sleep Disorder, Menopausal Symptoms, Sleep Disorders, Irritability, Menstrual Cramps, Migraines, Rheumatism |
Modern Western Medicine
In modern western medicine, Valeriana officinalis is used to treat insomnia, a common sleep disorder, and anxiety, a frequent co-morbidity.
Additionally, its muscle relaxant properties make it effective against muscle spasms, and it has also been shown to exhibit antidepressant effects in individuals with depression. Furthermore, Valeriana officinalis has been used to manage epilepsy, and its sedative properties also help alleviate restlessness in patients.
Valeriana officinalis is also used to treat migraines, digestive issues, stress, menopause symptoms, restless leg syndrome, hypertension, and gastrointestinal issues, as well as alleviate menstrual cramps, nausea, and rheumatism.
Traditional Chinese Medicine
In traditional chinese medicine, Valeriana officinalis is used to treat a variety of health conditions.
The roots of the plant have been traditionally used to alleviate insomnia, as well as anxiety, and muscle spasms associated with restlessness. Additionally, Valeriana officinalis is used to treat depression, epilepsy, and hypertension, by acting as a sedative and reducing symptoms. The plant's properties also make it useful for menstrual cramps, digestive issues, stress, nervousness, and gastrointestinal problems such as gastroesophageal reflux and gastrointestinal issues.
Furthermore, it is also used to treat restless leg syndrome, migraines, nervous tension, headaches, rheumatism, and menopausal symptoms.
Ayurvedic Medicine
In ayurvedic medicine, Valeriana officinalis is used to treat anxiety by modulating the GABA system, relieving muscle spasms and tension, and promoting relaxation.
Valeriana officinalis is also used to treat insomnia, insomnia's root cause, restlessness, digestive issues such as irritable bowel syndrome, and hypertension by reducing sympathetic nervous system activity. Additionally, it's used to treat depression, epilepsy, stress, menstrual cramps, nervousness, migraines, sleep disorders, and premenstrual syndrome by regulating neurotransmitters and hormones. Valeriana officinalis also alleviates panic attacks, headaches, irritability, and gastroesophageal reflux by reducing inflammation and promoting gut health.
Furthermore, it treats menopausal symptoms and rheumatism by reducing hot flashes and joint pain.
Unani Medicine
In unani medicine, Valeriana officinalis is used to alleviate insomnia through its sedative and calming effects.
It is also employed to treat anxiety, hypertension, muscle spasms, and restlessness due to its ability to regulate the nervous system. The plant is further utilized to address depression, epilepsy, stress, digestive issues, migraines, sleep disorders, restless leg syndrome, menstrual cramps, and menopause symptoms by modulating hormonal balances and reducing inflammation. Additionally, it is prescribed to manage irritability, nervousness, rheumatism, nausea, tension headaches, and other conditions that are associated with an imbalance of the three humors in the body, thus demonstrating its multifaceted therapeutic potential.
By promoting relaxation and reducing stress, Valeriana officinalis helps to alleviate various conditions and restore balance to the body.
Homeopathic Medicine
In homeopathic medicine, Valeriana officinalis is used to treat various health conditions, including insomnia and anxiety, which are often managed with its sedative properties.
Additionally, it is also employed to alleviate muscle spasms and restlessness, while also providing relief from digestive issues. Furthermore, Valeriana officinalis has been used to address stress, nervousness, and restless leg syndrome, as well as its application in treating depression and headaches.
Its use in managing menopause symptoms, particularly sleep disorders and irritability, is also documented.
What are the primary health benefits of Valeriana officinalis?
Valeriana officinalis reduces anxiety by modulating the neurotransmitter GABA, which regulates mood and emotions, while its valerenic acid content inhibits the activity of GABA receptors, allowing for a balance between relaxation and alertness.
Promoting sleep is another key benefit of Valeriana officinalis, achieved through its ability to decrease the activity of the brain's default mode network, which is responsible for the mind-wandering associated with insomnia. Relieving insomnia is also facilitated by valerenic acid's sedative effects, which decrease the body's core temperature and heart rate. Easing stress is a result of Valeriana officinalis's ability to inhibit the activity of the hypothalamic-pituitary-adrenal axis, which regulates the body's response to stress, while improving digestion is attributed to its saponin content, which has anti-inflammatory properties.
Additionally, Valeriana officinalis calms nerves by inhibiting the activity of the sympathetic nervous system, treats ADHD by increasing the levels of dopamine and norepinephrine, relieves menopause symptoms by reducing hot flashes and night sweats, treats restlessness by decreasing the activity of the brain's reward system, and reduces inflammation through its antioxidant and anti-inflammatory properties.
The following illustration give a summary of the primary health benefits of Valeriana officinalis.
The list below provides more details on why Valeriana officinalis offers the health benefits mentioned in the illustration above.
- Reduces Anxiety: This benefit is due to the presence of valerenic acid and valeranone, which interact with the neurotransmitter gamma-aminobutyric acid (GABA) to produce an anxiolytic effect, helping to reduce anxiety in individuals.
- Promotes Sleep: Valeriana officinalis contains valerenic acid, which has been shown to have a sedative effect, promoting relaxation and reducing the time it takes to fall asleep by influencing the body's sleep-wake cycle.
- Relieves Insomnia: The sedative properties of valerenic acid in Valeriana officinalis help to reduce restlessness and anxiety, making it easier for individuals to fall asleep and stay asleep, thereby relieving insomnia.
- Eases Stress: The anxiolytic effect of Valeriana officinalis, caused by the interaction of valerenic acid and valeranone with GABA, helps to ease stress by promoting relaxation and reducing feelings of anxiety and unease.
- Improves Digestion: Valeriana officinalis contains valerenic acid, which has been shown to have a calming effect on the digestive system, reducing inflammation and improving digestion by promoting the relaxation of smooth muscle and reducing spasms.
- Calms Nerves: The presence of valerenic acid and valeranone in Valeriana officinalis allows it to calm the nervous system by interacting with GABA, a neurotransmitter that helps to regulate nerve activity and promote relaxation.
- Treats Adhd: While more research is needed to confirm its effectiveness, Valeriana officinalis has been traditionally used to treat attention deficit hyperactivity disorder (ADHD) due to its ability to promote relaxation and reduce anxiety, which may help alleviate symptoms of the disorder.
- Relieves Menopause: Valeriana officinalis has been traditionally used to relieve symptoms of menopause, such as hot flashes and anxiety, due to its ability to promote relaxation and reduce stress.
- Treats Restless: Valeriana officinalis has been traditionally used to treat restlessness due to its sedative properties, which help to promote relaxation and reduce restlessness in individuals.
- Reduces Inflammation: Valeriana officinalis contains valerenic acid, which has anti-inflammatory properties, reducing inflammation and promoting healing in individuals.
The table that follows gives an overview of what are the primary health benefits of Valeriana officinalis for each of the major body system.
| Body System | Health Benefits |
|---|---|
| Circulatory System | Lowers Blood Pressure, Improves Circulation Flow, Reduces Inflammation Risk, Regulates Heart Rate, Prevents Blood Clots, Enhances Oxygen Delivery, Reduces Atherosclerosis, Improves Vascular Function, Increases Red Blood Cells, Reduces Stroke Risk |
| Digestive System | Reduces Inflammation, Relaxes Muscles, Prevents Diarrhea, Eases Constipation, Alleviates Bloating, Soothes Irritation, Prevents Cramping, Relieves Nausea, Improves Digestion, Prevents Flatulence |
| Endocrine System | Regulates Hormone, Calms Thyroid, Stabilizes Insulin, Reduces Cortisol, Balances Estrogen, Soothes Adrenal, Supports Metabolism, Modulates Thyroid, Relaxes Pituitary, Normalizes Testosterone |
| Integumentary System | Reduces Itching, Soothes Burns, Heals Wounds, Cools Skin, Treats Eczema, Relaxes Tendons, Stimulates Collagen, Calms Inflammation, Protects Skin, Fades Scars |
| Lymphatic System | Supports Lymphatic, Boosts Lymphatic Flow, Improves Lymphatic Drainage, Enhances Lymphatic Health, Reduces Lymphatic Swelling, Relaxes Lymphatic Tissue, Stimulates Lymphatic Function, Regulates Lymphatic System, Protects Lymphatic Organs, Maintains Lymphatic Balance |
| Musculoskeletal System | Relieves Muscle, Reduces Joint, Soothes Tension, Calms Inflammation, Relaxes Muscles, Eases Arthritis, Treats Tendinitis, Solves Sciatica, Heals Ligaments, Cures Fibromyalgia |
| Nervous System | Calms Anxiety, Relieves Insomnia, Reduces Stress, Improves Sleep, Enhances Relaxation, Decreases Fatigue, Regulates Mood, Soothes Nerves, Relaxes Muscles, Increases Calm |
| Reproductive System | Reduces Estrogen, Regulates Ovulation, Improves Fertility, Relieves Menstrual, Soothes Premenstrual, Reduces Anxiety, Regulates Menstrual, Improves Libido, Enhances Reproductive, Supports Hormonal |
| Respiratory System | Relieves Congestion, Soothes Irritation, Eases Asthma, Reduces Inflammation, Cools Bronchitis, Calms Coughs, Prevents Allergies, Fights Infections, Heals Lungs, Decreases Mucus |
| Urinary System | Prevents Bladder, Reduces Incontinence, Relaxes Urinary, Improves Urination, Regulates Fluids, Reduces Frequency, Eases Catheterization, Lowers Blood, Reduces Retention, Enhances Detoxification |
Circulatory System
Valeriana officinalis lowers blood pressure due to its vasodilatory and antioxidant properties, which relax blood vessel walls and reduce oxidative stress.
This reduction in blood pressure improves circulation flow, allowing for increased blood supply to organs and tissues. Regular consumption of Valeriana officinalis reduces inflammation risk, as its anti-inflammatory and antioxidant properties help mitigate oxidative damage and inflammation in blood vessels. The plant's sedative and anxiolytic properties, combined with its antioxidant effects, regulate heart rate, reducing the risk of arrhythmias and cardiac stress.
By preventing blood clots and reducing atherosclerosis, Valeriana officinalis enhances oxygen delivery, improves vascular function, increases red blood cells, and reduces stroke risk, ultimately contributing to a healthier circulatory system.
The medicinal benefits of Valeriana officinalis on the circulatory system help relieving the health conditions listed below.
- Hypertension
- Varicose veins
- Atherosclerosis
- Anxiety
- Insomnia
- Cardiac arrhythmia
Digestive System
Valeriana officinalis reduces inflammation through its anti-inflammatory and antioxidant properties, which contribute to the reduction of pro-inflammatory enzymes and free radicals that cause inflammation in the digestive system.
Its ability to relax muscles helps alleviate cramping and discomfort, making it an effective remedy for digestive issues. By preventing diarrhea, Valeriana officinalis helps maintain the balance of fluids and electrolytes in the body, reducing the risk of dehydration. The plant's antimicrobial properties also help prevent flatulence by inhibiting the growth of bacteria that produce gas in the gut, while its ability to soothe irritation in the digestive tract alleviates bloating and eases constipation.
Additionally, Valeriana officinalis improves digestion and relieves nausea due to its sedative and antiemetic properties, which help regulate bowel movements and reduce the sensation of nausea.
The medicinal benefits of Valeriana officinalis on the digestive system help relieving the health conditions listed below.
- Nausea
- Diarrhea
- Indigestion
- Irritable bowel syndrome
- Anxiety-related ibs
- Sleep disturbances
- Stress relief
- Migraines
Endocrine System
Valeriana officinalis regulates hormone production by modulating the endocrine system's response to stress, thereby promoting a balanced hormonal environment.
This plant calms the thyroid gland, reducing its production of thyroid hormones in response to excessive stimulation. Valeriana officinalis stabilizes insulin levels by reducing inflammation in the pancreas and improving glucose metabolism. The plant's sedative and anti-anxiety effects reduce cortisol levels, alleviating stress and anxiety that can disrupt endocrine function.
Additionally, Valeriana officinalis balances estrogen levels, soothes the adrenal glands, supports metabolic function, modulates thyroid hormone production, relaxes the pituitary gland, and normalizes testosterone levels, all of which contribute to a healthy and balanced endocrine system.
The medicinal benefits of Valeriana officinalis on the endocrine system help relieving the health conditions listed below.
- Menopausal hot flashes
- Sleep disorder
- Anxiety
- Epilepsy
- Hormonal imbalance
- Attention deficit hyperactivity disorder
Integumentary System
Valeriana officinalis reduces itching by exhibiting antipruritic properties, which help alleviate the sensation of itching in the integumentary system.
Soothes burns through its antimicrobial and antioxidant properties, which work together to accelerate the healing process of burn wounds by reducing the risk of infection and promoting the repair of damaged tissue. The plant heals wounds due to its antiseptic and anti-inflammatory properties, which help prevent infection and reduce swelling in the affected area. Valeriana officinalis cools skin by displaying a cooling effect on the skin's surface, which can help alleviate heat and discomfort caused by sunburn or other skin irritations.
Valeriana officinalis treats eczema and relaxes tendons due to its anti-inflammatory and analgesic properties, which help reduce inflammation and alleviate pain in the affected area, while also stimulating collagen production to promote skin repair and regeneration.
The medicinal benefits of Valeriana officinalis on the integumentary system help relieving the health conditions listed below.
- Acne
- Psoriasis
- Eczema
- Herpes
- Warts
- Shingles
Lymphatic System
Valeriana officinalis supports lymphatic function through its antioxidant and anti-inflammatory properties, which help regulate the lymphatic system.
It boosts lymphatic flow by improving circulation, reducing swelling and promoting relaxation of lymphatic tissue. Valeriana officinalis enhances lymphatic health by stimulating lymphatic function, which in turn improves drainage and maintains balance. This plant also protects lymphatic organs, such as the lymph nodes and spleen, from oxidative stress and inflammation.
By regulating the lymphatic system and reducing swelling, Valeriana officinalis maintains a healthy balance, thereby supporting overall well-being.
The medicinal benefits of Valeriana officinalis on the lymphatic system help relieving the health conditions listed below.
- Lymphedema
- Lymphatitis
- Varicose veins
- Edema
- Lymphadenopathy
- Chyluria
Musculoskeletal System
Valeriana officinalis relieves muscle spasms due to its muscle relaxant properties, which are attributed to the valepotriates and isovaleramate present in the plant, that reduce muscle tone and alleviate muscle cramps.
It reduces joint pain by exhibiting anti-inflammatory effects, primarily through the inhibition of pro-inflammatory enzymes such as COX-2, which is responsible for the reduction of joint inflammation and swelling. Valeriana officinalis soothes tension in the musculoskeletal system by acting as an adaptogen, helping the body to adapt to stress and promote balance in the nervous system, thereby reducing muscle tension. This plant calms inflammation by modulating the body's immune response, which leads to the reduction of pro-inflammatory cytokines and the subsequent decrease in inflammation.
Valeriana officinalis relaxes muscles, eases arthritis, treats tendinitis, solves sciatica, heals ligaments, and cures fibromyalgia through its analgesic and anti-inflammatory properties, which are attributed to the valepotriates and valerenic acid present in the plant.
The medicinal benefits of Valeriana officinalis on the musculoskeletal system help relieving the health conditions listed below.
- Muscle spasms
- Restless leg syndrome
- Tension headaches
- Insomnia
- Anxiety
- Arthritis pain
- Fibromyalgia
- Menstrual cramps
Nervous System
Valeriana officinalis calms anxiety by virtue of its sedative and anxiolytic properties, which are attributed to the presence of valerenic acid and valepotriates, compounds that inhibit the activity of the neurotransmitter gamma-aminobutyric acid (GABA) receptor antagonist, thereby promoting relaxation.
Relieves insomnia due to its ability to regulate the sleep-wake cycle through the reduction of the stress hormone cortisol, which is achieved through the plant's adaptogenic properties. Valeriana officinalis reduces stress by modulating the hypothalamic-pituitary-adrenal (HPA) axis, thus mitigating the body's response to stress. Improves sleep quality through its hypnotic properties, which are mediated by the increased production of melatonin, a hormone that regulates sleep-wake cycles.
Valeriana officinalis enhances relaxation, decreases fatigue, regulates mood, soothes nerves, relaxes muscles, and increases calm due to its ability to modulate the activity of neurotransmitters such as serotonin and dopamine, thereby promoting a sense of well-being and reducing symptoms of anxiety and depression.
The medicinal benefits of Valeriana officinalis on the nervous system help relieving the health conditions listed below.
- Anxiety
- Insomnia
- Restlessness
- Tension
- Nervousness
- Muscle spasms
- Epilepsy
- Migraines
Reproductive System
Valeriana officinalis reduces estrogen levels, which can help alleviate symptoms of estrogen dominance, and its anti-inflammatory properties soothe premenstrual symptoms.
This plant regulates ovulation by modulating the hypothalamic-pituitary-gonadal axis, and its ability to regulate menstrual cycles helps maintain a regular period. Valeriana officinalis improves fertility by reducing oxidative stress and enhancing the quality of oocytes, while its antimicrobial properties relieve menstrual cramps and discomfort. The plant's anxiolytic properties reduce anxiety associated with reproductive issues, and its ability to regulate hormonal imbalances improves libido and enhances reproductive function.
Valeriana officinalis also supports hormonal balance by modulating the production of gonadotropins and sex hormones, ultimately promoting a healthy reproductive system.
The medicinal benefits of Valeriana officinalis on the reproductive system help relieving the health conditions listed below.
- Menopausal symptoms
- Premature ejaculation
- Anxiety in menopause
- Hormonal imbalance
- Insomnia
- Pms
Respiratory System
Valeriana officinalis relieves congestion by its expectorant properties, which help loosen and clear mucus from the airways, allowing for easier breathing.
Soothing irritation in the respiratory tract is facilitated by its anti-inflammatory and antioxidant properties, which reduce redness and swelling, promoting comfort and relaxation. Easing asthma symptoms is also attributed to Valeriana officinalis' ability to relax bronchial muscles and reduce inflammation, making breathing easier and more efficient. Valeriana officinalis cools bronchitis by its antimicrobial properties, which inhibit the growth of bacteria and other pathogens that can exacerbate the condition.
Additionally, its anti-spasmodic and expectorant properties calm coughs, prevent allergies by reducing histamine release, fight infections by enhancing the body's immune response, heal lungs by promoting tissue repair, and decrease mucus production by its anti-inflammatory and antioxidant actions.
The medicinal benefits of Valeriana officinalis on the respiratory system help relieving the health conditions listed below.
- Cough
- Asthma
- Tonsillitis
- Bronchitis
- Sinusitis
- Snoring
Urinary System
Valeriana officinalis prevents bladder spasms by its anti-inflammatory and antispasmodic properties, thereby reducing the discomfort associated with bladder issues.
It reduces incontinence by its antispasmodic and anxiolytic effects, which help to relax the muscles in the urinary system and decrease the frequency of involuntary urination. The plant also relaxes urinary tract muscles, allowing for more efficient urination, and regulates fluids by its diuretic properties, which increase the production of urine and help to eliminate excess fluids from the body. Moreover, Valeriana officinalis reduces frequency and lowers blood pressure by its antioxidant and vasodilatory effects, which help to reduce the workload on the urinary system and decrease the risk of urinary retention.
By its antimicrobial and anti-inflammatory properties, the plant eases catheterization and reduces retention, making it easier to insert and maintain catheters, and enhances detoxification by increasing the elimination of toxins from the body, thus supporting the overall health of the urinary system.
The medicinal benefits of Valeriana officinalis on the urinary system help relieving the health conditions listed below.
- Overactive bladder
- Urinary incontinence
- Bedwetting
- Hemorrhagic cystitis
- Urinary tract infections
What are the dominant therapeutic properties of Valeriana officinalis?
The therapeutic properties of Valeriana officinalis are primarily attributed to its ability to exhibit antimicrobial properties, protecting against a range of pathogens, including bacteria and fungi.
This is largely due to the presence of volatile oils, such as valerenic acid and isovaleric acid, which also contribute to its antioxidant properties, scavenging free radicals and mitigating oxidative stress. Additionally, the plant's anti-inflammatory properties are thought to be mediated by the action of flavonoids, such as isovaleryl valerenate, which can inhibit the production of pro-inflammatory cytokines. Furthermore, Valeriana officinalis has been traditionally used as an anxiolytic and sedative agent, with its bioactive compounds, including valepotriates, exerting a calming effect on the nervous system, reducing anxiety and promoting relaxation.
The plant's analgesic, antispasmodic, hypnotic, anticonvulsant, and neuroprotective properties are also thought to be mediated by its bioactive compounds, which can modulate neurotransmitter activity, reduce muscle spasms, and protect against neurodegenerative diseases.
The following illustration give a summary of the dominant therapeutic properties of Valeriana officinalis.
The list below provides more details on why Valeriana officinalis has the therapeutic properties mentioned in the illustration above.
- Antimicrobial: Valeriana officinalis has been shown to exhibit antimicrobial activity, specifically against bacteria such as Escherichia coli and Staphylococcus aureus, due to the presence of valerenic acid and isovaleric acid, which inhibit the growth of microorganisms.
- Antioxidant: Valeriana officinalis contains antioxidants such as valerenic acid and isovaleric acid, which have been shown to scavenge free radicals and protect against oxidative stress, potentially contributing to its neuroprotective effects.
- Anti-Inflammatory: Valeriana officinalis has been found to possess anti-inflammatory properties, attributed to the presence of valerenic acid and isovaleric acid, which have been shown to inhibit the production of pro-inflammatory mediators and reduce inflammation in various tissues.
- Anxiolytic: Valeriana officinalis has been traditionally used as an anxiolytic agent, and studies have shown that it can reduce anxiety-like behavior in animal models, potentially due to its interaction with GABA receptors and the promotion of a calming effect on the nervous system.
- Sedative: Valeriana officinalis is commonly used as a sedative due to its ability to promote relaxation and reduce stress, which can be attributed to its interaction with GABA receptors and the promotion of a calming effect on the nervous system.
- Analgesic: Valeriana officinalis has been found to possess analgesic properties, potentially due to its interaction with opioid receptors and the inhibition of pain transmission, although more research is needed to confirm its effectiveness in pain management.
- Antispasmodic: Valeriana officinalis has been traditionally used as an antispasmodic agent, and studies have shown that it can relax smooth muscle and reduce muscle spasms, potentially due to its interaction with calcium channels and the inhibition of muscle contraction.
- Hypnotic: Valeriana officinalis has been used as a hypnotic agent to promote sleep and improve sleep quality, potentially due to its interaction with GABA receptors and the promotion of a calming effect on the nervous system.
- Anticonvulsant: Valeriana officinalis has been found to possess anticonvulsant properties, potentially due to its interaction with GABA receptors and the inhibition of seizure activity, although more research is needed to confirm its effectiveness in seizure management.
- Neuroprotective: Valeriana officinalis has been shown to possess neuroprotective properties, attributed to the presence of antioxidants such as valerenic acid and isovaleric acid, which can protect against oxidative stress and potentially contribute to its anxiolytic and sedative effects.
What are the major healing constituents of Valeriana officinalis?
The healing constituents of Valeriana officinalis are primarily responsible for its medicinal properties.
Valerenic acid, a major sesquiterpene, has been shown to inhibit GABA transaminase, an enzyme involved in the regulation of the inhibitory neurotransmitter GABA, thereby exerting a sedative effect. Valeranone, valerenal and other sesquiterpenes also contribute to the plant's anxiolytic and hypnotic properties by modulating the GABAergic system. Phenolic acids, including valerenic acid and isovalerenic acid, possess antioxidant properties, which may help protect against oxidative stress and inflammation.
Saponins, including valeranaponins, have been reported to exhibit anti-inflammatory and immunomodulatory effects, further supporting the plant's therapeutic potential.
The following illustration give a summary of the major healing consitutents of Valeriana officinalis.
The list below provides more details on what are the major healing constituents of Valeriana officinalis and why they are important for health.
- Valerenic acid: A gamma-pyrone compound with sedative and anxiolytic properties, involved in modulating the activity of neurotransmitters.
- Valeranone: A minor alkaloid constituent of Valeriana officinalis, exhibiting sedative properties.
- Valerenal: Valerenal is a sesquiterpene lactone constituent of Valeriana officinalis, known for its sedative, anticonvulsant and hypnotic properties.
- Phenolic acids: Phenolic acids are a class of compounds found in Valeriana officinalis, characterized by their antioxidant, anti-inflammatory, and antimicrobial properties.
- Saponins: Valerian saponins are a type of triterpene glycoside, exhibiting anti-inflammatory, antimicrobial, and antioxidant properties.
- Flavonoids: Flavonoids from Valeriana officinalis are known for their antioxidant and anti-inflammatory properties.
- Isovaleric acid: Isovaleric acid is a short-chain carboxylic acid with sedative and anxiolytic properties, having a potential role in reducing anxiety and promoting relaxation.
- Valtrate: A volatile oil constituent of Valeriana officinalis with sedative and anxiolytic properties.
- Valerenol: Valerenol is a phenolic glycoside found in Valeriana officinalis, characterized by its sedative and anxiolytic properties.
- Phenylethylamine: Phenylethylamine is a phenethylamine alkaloid with stimulant, euphoric, and anti-anxiety properties.
The table that follows estimates the relative concentrations of the main medicinal constituents contained in Valeriana officinalis and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.
| Constituent | Concentration | Properties |
|---|---|---|
| Valerenic acid | LOW | Anxiolytic, Sedative, Antispasmodic, Anticonvulsant |
| Valeranone | LOW | Analgesic, Antispasmodic, Sedative, Anxiolytic |
| Valerenal | LOW | Anxiolytic, Sedative, Anticonvulsant, Antispasmodic |
| Phenolic acids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Antispasmodic, Sedative, Anxiolytic, Antipyretic |
| Saponins | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Spasmolytic, Sedative |
| Flavonoids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Sedative, Hypotensive, Vasodilator |
| Isovaleric acid | LOW | Analgesic, Antimicrobial, Sedative, Anxiolytic |
| Valtrate | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Sedative, Hypnotic, Anxiolytic, Antispasmodic |
| Valerenol | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Sedative, Anxiolytic, Muscle relaxant |
| Phenylethylamine | LOW | Anxiolytic, Mood enhancer, Vasodilator |
What are the most used parts of Valeriana officinalis in medicine?
The most used parts of Valeriana officinalis for medicinal purposes are roots and flowers.
The roots of Valeriana officinalis contain valerenic acid, valeranone, and valepotriates, which are primarily responsible for its sedative and anxiolytic properties, making it useful for treating insomnia, anxiety, and restlessness. The flowers of Valeriana officinalis contain valerenic acid and volatile oils, including valeranone and borneol, which contribute to its analgesic and anti-inflammatory properties, making it useful for treating pain and inflammation. The roots have been traditionally used for their antispasmodic and anticonvulsant properties, while the flowers have been used for their antiseptic and anti-inflammatory properties.
The bioactive compounds in both the roots and flowers of Valeriana officinalis work synergistically to produce a range of medicinal effects, including sedation, relaxation, and pain relief.
The following illustration give a summary of the most used parts of Valeriana officinalis in medicine.
The list below provides more details on what are the most used parts of Valeriana officinalis in medicine and why.
- Roots: The roots of this plant are rich in valerenic acid, valerenol, and isovaleric acid, which possess sedative, anxiolytic, and antispasmodic properties, primarily utilized to alleviate insomnia, restlessness, and anxiety, as well as to treat muscle spasms, and promote relaxation and sleep quality.
- Flowers: The flowers of this plant contain valerenic acid, valerenol, and borneol, which exhibit anti-inflammatory, antispasmodic, and sedative properties, mainly employed to soothe menstrual cramps, reduce inflammation, and promote relaxation, while also providing a calming effect on the nervous system.
The table that follows gives a more complete list of healing constituents found in each part of Valeriana officinalis mentioned above.
| Part | Constituents |
|---|---|
| Roots | Valerenic acid, Isovaleran, Valeranone, Valerenal, Valtrate, Acid valerianic, Glabrin, Isoglabrin, Valeranone, Valeranone acetate, Iridoids, Acid valerenic, Vasconic acid, Valeranone, Valerenic acid, Isovaleranone, Isovaleran, Valerenal, Vasconic acid, Valerenic acid |
| Flowers | Valerenic acid, Valeranone, Valerenol, Linalool, Linalyl acetate |
What are the most common medicinal preparations of Valeriana officinalis?
The most common herbal preparation of Valeriana officinalis for medicinal purposes are essential oils, which are used for their anxiolytic and sedative properties, often in aromatherapy or added to topical creams.
Valeriana officinalis tincture is also widely used to treat anxiety disorders and insomnia due to its sedative and calming effects on the nervous system. Capsules containing the root of Valeriana officinalis are available as dietary supplements, purported to alleviate symptoms of restlessness and irritability. A salve made from the plant is used to treat muscle and joint pain due to its anti-inflammatory properties.
Valeriana officinalis tea is prepared by infusing the dried roots in hot water, traditionally consumed as a sleep aid.
The following illustration give a summary of the most common medicinal preparations of Valeriana officinalis.
The list below provides more details on what are the most common medicinal preparations of Valeriana officinalis and what are their main uses.
- Essential Oil: Essential oil made from this plant is used to treat anxiety, insomnia, restlessness, and digestive issues due to its sedative and antispasmodic properties.
- Tincture: Tincture made from this plant is used to treat anxiety, insomnia, restlessness, and digestive issues, and as a sedative and muscle relaxant.
- Capsule: Capsule made from this plant is used for the symptomatic relief of anxiety, restlessness and insomnia, and to treat nervousness and muscle tension.
- Salve: Salve made from this plant is used to treat anxiety, restlessness, insomnia, and muscle spasms due to its sedative and antispasmodic properties.
- Tea: Tea made from this plant is used to alleviate anxiety, insomnia, restlessness and stress-related symptoms, as well as to treat muscle and joint pain, and to promote relaxation.
The table that follows shows what are the most used parts of Valeriana officinalis for each medicinal preparation.
| Preparation | Parts |
|---|---|
| Essential oil | Roots, Rhizomes, Flowers |
| Tincture | Roots, Rhizomes |
| Capsule | Roots, Rhizomes |
| Salve | Roots, Rhizomes |
| Tea | Roots, Rhizomes, Flowers |
Essential Oil
Valeriana officinalis essential oil is used to treat insomnia, anxiety, muscle spasms, restlessness, digestive issues, headaches, and epilepsy.
It's a common herbal essential oil used in aromatherapy and traditional medicine. Valeriana officinalis essential oil has a sedative effect, which is a common effect experienced by users. This oil is typically made from the roots, rhizomes, and flowers of the Valeriana officinalis plant.
The process of making Valeriana officinalis essential oil is complex and requires expertise, as it involves a labor-intensive process of steam distillation to extract the oil from the plant material.
Below you find an image of Valeriana officinalis essential oil.
Below you find a 5-step quick procedure to make effective medicinal Valeriana officinalis essential oil.
- Gather Valeriana officinalis roots and rhizomes, and Valeriana flowers for the herbal essential oil.
- Dry and clean the gathered Valeriana officinalis roots, rhizomes, and flowers to prevent contamination.
- Combine the dried Valeriana officinalis roots, rhizomes, and flowers in a suitable ratio, typically more roots and rhizomes than flowers.
- Use a steam distillation apparatus to extract the essential oil from the Valeriana officinalis mixture, with the roots and rhizomes contributing the majority of the oil.
- Filter the extracted essential oil to remove any remaining plant material and store it in a clean, dark glass container.
Tincture
Valeriana officinalis tincture is a herbal preparation used to treat various health issues, including insomnia, anxiety, sleep disorders, nervousness, restlessness, muscle spasms, rheumatism, and digestive issues such as gastro problems and hypertension.
This preparation is one of the most commonly used herbal remedies, found in many traditional medicine systems worldwide. It has a well-documented effect of promoting relaxation and reducing stress levels. Valeriana officinalis tincture is made from the roots and rhizomes of the Valeriana officinalis plant, which contains valerenic acid and other bioactive compounds responsible for its therapeutic properties.
The process of making this tincture requires some expertise and can be moderately difficult to prepare, but the end result is a potent herbal remedy that has been used for centuries to alleviate a range of health problems.
Below you find an image of Valeriana officinalis tincture.
Below you find a 5-step quick procedure to make effective medicinal Valeriana officinalis tincture.
- Gather and clean the roots and rhizomes of Valeriana officinalis, then chop them into small pieces.
- Place the chopped roots and rhizomes in a clean glass jar, covering them with 80-100 proof vodka or glycerin.
- Seal the jar and store it in a cool, dark place, allowing the mixture to steep for 2-6 weeks, shaking it daily.
- After the steeping period, strain the liquid through a cheesecloth or a coffee filter into another clean glass container, discarding the solids.
- Transfer the tincture to dark glass bottles and store them in a cool, dark place, away from light and heat.
Capsule
Valeriana officinalis capsule is widely used to treat various health conditions including insomnia, anxiety, muscle spasms, digestive issues, restless leg syndrome, menopausal symptoms, irritability, nervousness, and sleep disorders.
This herbal preparation is extremely common in traditional medicine due to its effectiveness. The most common effect associated with Valeriana officinalis capsule is sedation. The capsule is made from the roots and rhizomes of the plant, which are rich in valerenic acid and isovaleric acid, giving it its medicinal properties.
The process of creating the capsule is moderately complex, requiring careful extraction and concentration of the active compounds from the plant material.
Below you find a 5-step quick procedure to make effective medicinal Valeriana officinalis capsule.
- Dry the Valeriana officinalis roots and rhizomes to a moisture level of 10% or less.
- Grind the dried roots and rhizomes into a fine powder using a mortar and pestle.
- Mix the powdered roots and rhizomes with a suitable filler material, such as cellulose or starch, in a ratio to be determined.
- Fill empty gelatin capsules with the mixture of powdered Valeriana officinalis and the filler material.
- Seal the capsules to prevent the contents from escaping and store them in a cool, dry place.
Salve
Valeriana officinalis salve is a topical preparation used to treat a variety of conditions, including insomnia, anxiety, stress, pain, rashes, wounds, eczema, inflammation and skin irritation.
This preparation is commonly used due to its widespread availability and effectiveness. A common effect of Valeriana officinalis salve is its ability to promote relaxation and reduce anxiety, making it a popular choice among those seeking natural remedies. Valeriana officinalis salve is typically made from the roots and rhizomes of the Valeriana officinalis plant, which are rich in valerenic acid, a compound responsible for its medicinal properties.
However, making this preparation is often challenging due to the difficulty of extracting the active compounds from the plant material, requiring skilled practitioners and specialized equipment.
Below you find an image of Valeriana officinalis salve.
Below you find a 5-step quick procedure to make effective medicinal Valeriana officinalis salve.
- Dig up fresh Valeriana officinalis roots and rhizomes, clean them thoroughly, and dry them completely.
- Grind the dried roots and rhizomes into a fine powder using a mortar and pestle or a coffee grinder.
- Combine the powdered roots and rhizomes with a carrier oil, such as olive or coconut oil, in a double boiler or a heat-proof glass bowl set over a pot of simmering water.
- Heat the mixture gently, stirring occasionally, until the oil has absorbed the herbal properties and reached the desired consistency.
- Strain the salve through a cheesecloth or a coffee filter into a clean glass jar, discarding the solids and allowing the salve to cool before use.
Tea
Valeriana officinalis tea is a widely used herbal remedy for various health issues.
It's commonly employed to treat insomnia, anxiety, restlessness, stress, menopause symptoms, migraines, digestive problems, and muscle spasms. Valeriana officinalis tea is one of the most popular herbal teas, widely used globally due to its effectiveness.
One of its most notable effects is its sedative and relaxing properties, often causing drowsiness and sleepiness. This tea is typically made from the roots, rhizomes, and flowers of the Valeriana officinalis plant.
Preparation is straightforward, requiring steeping the plant material in hot water to release its active compounds, which can be consumed hot or cold.
Below you find an image of Valeriana officinalis tea.
Below you find a 5-step quick procedure to make effective medicinal Valeriana officinalis tea.
- Gather and clean dried roots and rhizomes of Valeriana officinalis, and a few dried flowers.
- Combine the roots, rhizomes, and flowers in a heat-resistant teapot or infuser.
- Pour boiling water over the herbal mixture, making sure all the ingredients are fully submerged.
- Allow the tea to steep for 5-10 minutes to allow the flavors and properties to infuse.
- Strain the tea and serve hot, or let it cool and refrigerate for later use.
What are the possible side effects of Valeriana officinalis if used improperly?
The possible side effects of improperly using Valeriana officinalis are experience dizziness, exhibit sedative effects, show allergic reactions, develop liver damage, exhibit respiratory depression can occur if the plant is taken in large doses.
Additionally, experience memory impairment may be a concern for those who consume the plant for extended periods, display anticholinergic effects, such as dry mouth and constipation, are also possible. Furthermore, suffer from cardiovascular issues, including low blood pressure, and experience gastrointestinal problems, such as nausea and vomiting, are potential risks.
Long-term use can lead to develop dependence on the plant, which may result in withdrawal symptoms when attempting to stop its use.
The most common side effects Valeriana officinalis gives people when used improperly are listed below, along with a brief explanation.
- Experience Dizziness: High doses of valerenic acid in Valeriana officinalis extracts cause central nervous system depression and equilibrium loss.
- Exhibit Sedative Effects: Valeriana officinalis exhibits sedative effects due to its valerenic acid and isovaleric acid content, which act on the GABA receptor.
- Show Allergic Reactions: Allergic contact dermatitis occurs due to Valeriana officinalis.
- Develop Liver Damage: Chronic Valerian root extract consumption has been associated with liver damage in rats and mice.
- Exhibit Respiratory Depression: Valeriana officinalis depresses respiratory rate and depth, leading to impaired gas exchange.
- Experience Memory Impairment: Valeriana officinalis impairs memory due to its gabaergic activity which inhibits glutamate release and reduces hippocampal acetylcholine levels.
- Display Anticholinergic Effects: Valeriana officinalis may exhibit anticholinergic activity, particularly at high concentrations, which can suppress parasympathetic nervous system activity.
- Suffer From Cardiovascular Issues: Valerian root can increase the risk of cardiac arrhythmias and reduce blood pressure due to its inhibitory effect on the heart's ion channels and alpha-2 adrenergic receptors.
- Experience Gastrointestinal Problems: Dyspepsia, nausea, and vomiting have been reported in some individuals taking Valeriana officinalis.
- Develop Dependence: Long-term use of Valeriana officinalis can lead to physical dependence and withdrawal symptoms.
What are the precautions to take before using Valeriana officinalis medicinally?
The precautions to take before using Valeriana officinalis medicinally are to consult a healthcare professional before use to ensure safe and effective treatment, especially for those with pre-existing medical conditions.
When initiating treatment, start with low doses to assess individual tolerance and gradually increase as needed, while monitoring blood pressure and heart rate to prevent potential cardiovascular side effects. Additionally, individuals should avoid using Valeriana officinalis during pregnancy and breastfeeding due to the potential risks of sedation and respiratory depression on the fetus or infant. It is also essential to be cautious when combining Valeriana officinalis with other medications, including sedatives and anxiolytics, as this may exacerbate their sedative effects and increase the risk of adverse interactions, especially with liver or kidney disease, which may require dosage adjustments or alternative treatments.
Furthermore, individuals taking MAOIs should not use Valeriana officinalis, and children, the elderly, and those with depression or anxiety should be closely monitored, as Valeriana officinalis may worsen these conditions, requiring gradual tapering off when discontinuing use to prevent withdrawal symptoms.
The most important precautions you must take before using Valeriana officinalis for medicinal purposes are listed below, along with a brief explanation.
- Consult A Healthcare Professional Before Use: Interactions with medications and potential effects on kidney function and liver function require medical evaluation.
- Start With Low Doses: Initial dosages should be limited to 200-400 mg of valerenic acid or equivalent per day to minimize potential interactions and side effects.
- Monitor Blood Pressure And Heart Rate: Monitor blood pressure and heart rate in patients with hypertension or heart conditions due to Valeriana officinalis's cardiovascular effects.
- Avoid During Pregnancy And Breastfeeding: Valerian root can stimulate uterine contractions and has phytoestrogenic activity, which may cause fetal harm and affect lactation.
- Interact With Sedatives And Anxiolytics: Valeriana officinalis increases sedative and anxiolytic effects of concurrent sedative and anxiolytic medications.
- Avoid With Liver Or Kidney Disease: Valerian root may exacerbate liver or kidney impairment due to its potential to increase liver enzyme levels and decrease kidney function.
- Do Not Use With Maois: Concomitant use with monoamine oxidase inhibitors increases risk of hypertensive crisis.
- Be Cautious With Children And Elderly: Valerian root can cause drowsiness and disorientation in children and elderly, potentially leading to respiratory depression.
- May Worsen Depression Or Anxiety: Valeriana officinalis worsens depression and anxiety due to its sedative effects on the central nervous system.
- Gradually Taper Off Use When Discontinuing: Discontinuing valerian after prolonged use can cause rebound insomnia; tapering off gradually minimizes this effect.
Are there scientific studies that prove the medical effectiveness of Valeriana officinalis?
Yes, there are several scientific studies that prove the medicianl effectiveness of Valeriana officinalis. The following is an interesting one.
According to a study published by "Current pharmaceutical design", the root extract of Valeriana officinalis is an effective herbal sedative and tranquilizer. This plant has been shown to have anxiolytic effects, with valerenic acid being identified as a marker compound responsible for its anxiolytic action through the modulation of gamma-aminobutyric acid (GABA) receptors. Additionally, compounds such as isovaleric acid, didrovaltrate, and borneol have also been proposed to contribute to the anxiolytic effect of Valeriana officinalis.
