large cranberry
Vaccinium macrocarpon · Accepted scientific name
Scientific literature: Very Extensive (773 studies) · ★★★★★
Large cranberry, scientifically known as Vaccinium macrocarpum, is a robust perennial shrub native to North American wetlands. Renowned for its tart, antioxidant-rich berries, this medicinal plant is widely utilized to support urinary tract health, combat oxidative stress, and provide essential vitamins, making it a powerhouse in traditional herbal wellness.
Names and Synonyms
Common Names
- American cranberry
- large cranberry
- Cramberry
- Wild Cranberry
- fenberry
Scientific Names
Accepted name
Vaccinium macrocarponSynonyms
- Oxycoca macrocarpa
- Vaccinium oblongifolium
- Oxycoca berberidacea
- Schollera macrocarpon
- Vaccinium macrocarpon f. eburnea
- Oxycoccus macrocarpos
- Vaccinium macrocarpon var. intermedium
- Vaccinium oxycoccos var. oblongifolium
- Oxycoccus palustris var. macrocarpos
Regional and Traditional Names
Spanish:
- cranberry
- arándano americano
- arándano trepador
- Arándano rojo americano
German:
- Großfrüchtige Moosbeere
- Grossfrüchtige Moosbeere
- Kranbeere
- Kraanbeere
- Kranichbeere
- Kränbeere
- Cranberry
- Kranbeere
- große Moosbeere
- Großfrüchtige Moosbeere
- Grossfruechtige Moosbeere
French:
- canneberge à gros fruits
- grande airelle rouge d’Amérique du Nord
- airelle à gros fruits
- airelle à gros fruits
- canneberge à gros fruits
- graines
- grande canneberge
- gros atoca
- gros atocas
- pommes de pré
- ronce d'Amérique
- Canneberge a gros fruits
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Ericales and the family Ericaceae, it is classified under the genus Vaccinium. As part of this taxonomic hierarchy, Vaccinium macrocarpum is identified by its specific botanical lineage.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Ericales |
| Family | Ericaceae |
| Genus | Vaccinium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific geographical distribution across several regions of Europe. In Northern Europe, it can be found within the territory of Great Britain. Its presence extends into Middle Europe, where it inhabits Belgium. Furthermore, the species is distributed across Germany and the Netherlands. Finally, its range reaches into the mountainous landscapes of Switzerland.
| Region | Area |
|---|---|
| Northern Europe | Great Britain |
| Middle Europe | Belgium |
| Middle Europe | Germany |
| Middle Europe | Netherlands |
| Middle Europe | Switzerland |
| Eastern Europe | Belarus |
| Eastern Europe | Baltic States |
| Western Canada | British Columbia |
| Eastern Canada | New Brunswick |
| Eastern Canada | Newfoundland |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Vaccinium macrocarpon is characterized by its status as a perennial species, allowing it to persist through multiple growing seasons. As a chamaephyte, its regenerative buds are located close to the soil surface, which helps the plant navigate its environmental conditions. While its physiological traits can exhibit specific adaptations to its habitat, it is categorized under the life form of a chamaephyte, ensuring its survival through seasonal cycles. Regarding its foliage, the plant is characterized as evergreen, maintaining its leaf structure throughout the year to support its long-term developmental processes.
- Deciduousness :
- evergreen
- Life form :
- chamaephyte
- Lifecycle :
- perennial
Morphology
The morphology of Vaccinium macrocarpum is characterized by its growth form as a woody shrub. It is a self-supporting plant that does not exhibit climbing behavior, such as a liana or vine, nor does it function as a parasite or an epiphyte, maintaining a strictly terrestrial existence. In terms of stature, the plant displays significant variation in height, with measurements ranging from a minimum of 0.02 m to a maximum of 1 m, resulting in an average plant height of approximately 1.3 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- shrub
- Parasite :
- independent
- Plant height max:
- 1 m
- Plant height mean:
- 1.3 m
- Plant height min:
- 0.02 m
- Woodiness :
- woody
Physiology
The physiology of Vaccinium macrocarpon is characterized by a C3 photosynthetic pathway, which is the standard carbon fixation mechanism for most temperate woody shrubs. The plant is strictly non-carnivorous, relying on its root system and soil nutrient uptake rather than the capture of prey for nitrogen or other essential minerals. Furthermore, its leaf morphology and resource allocation are reflected in a Specific Leaf Area (SLA) with a mean value of 124 cm²/g, indicating a moderate investment in leaf thickness and structural density relative to its surface area.
- Carnivory :
- non-carnivorous
- Photosynthetic pathway :
- C3
- Specific Leaf Area (SLA) mean:
- 124 cm²/g
Reproduction
The reproduction of Vaccinium macrocarpon is driven by a sexual process, as asexual reproduction is absent. The flowering period typically begins in June and continues through August. The plant relies on biotic pollination syndromes, specifically utilizing insects with a strong preference for bees to facilitate fertilization; notably, self-fertilization is absent, necessitating these external pollinators. Following successful pollination, the plant produces fruit characterized as a berry. These fruits are indehiscent, meaning they do not split open at maturity to release their contents. The seeds produced are extremely small, with a consistent mean, minimum, and maximum mass of approximately 0.00082 g. Dispersal is achieved through a zoochorous syndrome, specifically via endozoochory, where the seeds are dispersed after being ingested by animals.
- Dehiscence :
- indehiscent
- Dispersal syndrome :
- zoochorous
- Dispersal syndrome :
- endozoochorous
- Flowering time :
- Jun
- Flowering time :
- Aug
- Fruit type :
- berry
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
- Reproduction asexual :
- absent
- Seed mass max:
- 0.00082 g
- Seed mass mean:
- 0.000824 g
- Self fertilization :
- absent
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Vaccinium macrocarpon has 2 reported plant parts identified across 4 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, seed.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Fruit | 3 supporting sources | ★★☆☆☆ |
| Seed | 1 supporting sources | ★☆☆☆☆ |
Fruit
- Journal of natural products
- Phytotherapy research : PTR
- Molecules (Basel, Switzerland)
Seed
- Molecules (Basel, Switzerland)
Chemicals
Vaccinium macrocarpon has 106 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include Anthocyanins, Ursolic acid, quercetin, Proanthocyanidin, CHLOROGENIC ACID.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Anthocyanins | 4 supporting sources | ★★☆☆☆ |
| Ursolic acid | 4 supporting sources | ★★☆☆☆ |
| quercetin | 4 supporting sources | ★★☆☆☆ |
| Proanthocyanidin | 3 supporting sources | ★★☆☆☆ |
| CHLOROGENIC ACID | 2 supporting sources | ★☆☆☆☆ |
| Condensed Tannins | 2 supporting sources | ★☆☆☆☆ |
| Flavonoids | 2 supporting sources | ★☆☆☆☆ |
| RUTIN | 2 supporting sources | ★☆☆☆☆ |
| myricetin | 2 supporting sources | ★☆☆☆☆ |
| triterpenoids | 2 supporting sources | ★☆☆☆☆ |
Anthocyanins
- Dr. Duke
- Plants (Basel, Switzerland)
- International journal of biopharmaceutical sciences
- Antioxidants (Basel, Switzerland)
Ursolic acid
- Dr. Duke
- Planta medica
- International journal of biopharmaceutical sciences
- Molecules (Basel, Switzerland)
quercetin
- Dr. Duke
- Pharmaceutical biology
- International journal of biopharmaceutical sciences
- Molecules (Basel, Switzerland)
Proanthocyanidin
- Journal of natural products
- Plants (Basel, Switzerland)
- Pharmaceutical biology
CHLOROGENIC ACID
- Dr. Duke
- Molecules (Basel, Switzerland)
Condensed Tannins
- Pharmaceutical biology
- Antioxidants (Basel, Switzerland)
Flavonoids
- Pharmaceutical biology
- Antioxidants (Basel, Switzerland)
RUTIN
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- European journal of pharmacology
myricetin
- Dr. Duke
- Molecules (Basel, Switzerland)
triterpenoids
- Dr. Duke
- Plants (Basel, Switzerland)
Activities
Vaccinium macrocarpon has 617 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antioxidant, Estrogenic, 11B-HSD-Inhibitor, 5-HETE-Inhibitor.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Anticancer | 3 supporting sources | ★★☆☆☆ |
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Estrogenic | 2 supporting sources | ★☆☆☆☆ |
| 11B-HSD-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| 5-HETE-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| 5-HT-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| 5-Lipoxygenase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| ACE-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| AP-1-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| ATPase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
Anticancer
- Dr. Duke
- Pharmaceutical biology
- Molecules (Basel, Switzerland)
Antioxidant
- Dr. Duke
- Molecules (Basel, Switzerland)
Estrogenic
- Dr. Duke
- Frontiers in pharmacology
11B-HSD-Inhibitor
- Dr. Duke
5-HETE-Inhibitor
- Dr. Duke
5-HT-Inhibitor
- Dr. Duke
5-Lipoxygenase-Inhibitor
- Dr. Duke
ACE-Inhibitor
- Dr. Duke
AP-1-Inhibitor
- Dr. Duke
ATPase-Inhibitor
- Dr. Duke
Conditions
Vaccinium macrocarpon has 14 reported investigations on conditions identified across 4 scientific publications and several other databases. The most consistently reported conditions include urinary tract infections, Influenza Virus, Urinary tract infections, antioxidant, biofilm.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Urinary tract infections | 2 supporting sources | ★☆☆☆☆ |
| Influenza virus | 1 supporting sources | ★☆☆☆☆ |
| Urinary tract infections | 1 supporting sources | ★☆☆☆☆ |
| Antioxidant | 1 supporting sources | ★☆☆☆☆ |
| Biofilm | 1 supporting sources | ★☆☆☆☆ |
| Cancer | 1 supporting sources | ★☆☆☆☆ |
| Cardiovascular diseases | 1 supporting sources | ★☆☆☆☆ |
| Cell adhesion | 1 supporting sources | ★☆☆☆☆ |
| Common cold | 1 supporting sources | ★☆☆☆☆ |
| Cystitis | 1 supporting sources | ★☆☆☆☆ |
Urinary tract infections
- Planta medica
- Journal of natural products
Influenza virus
- Frontiers in microbiology
Urinary tract infections
- Current issues in molecular biology
Antioxidant
- Molecules (Basel, Switzerland)
Biofilm
- International journal of clinical pediatric dentistry
Cancer
- International journal of biopharmaceutical sciences
Cardiovascular diseases
- Current pharmaceutical design
Cell adhesion
- International journal of clinical pediatric dentistry
Common cold
- International journal of biopharmaceutical sciences
Cystitis
- Journal of clinical gastroenterology
Preparations
Vaccinium macrocarpon has 10 reported preparations identified across 4 scientific publications and several other databases. The most consistently reported preparations include Extracts, alcohol fractions, aqueous-ethanolic extracts (30/70), extracts of cranberry fruit, fermented extract.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Extracts | 1 supporting sources | ★☆☆☆☆ |
| Alcohol fractions | 1 supporting sources | ★☆☆☆☆ |
| Aqueous-ethanolic extracts (30/70) | 1 supporting sources | ★☆☆☆☆ |
| Extracts of cranberry fruit | 1 supporting sources | ★☆☆☆☆ |
| Fermented extract | 1 supporting sources | ★☆☆☆☆ |
| Fruit juice | 1 supporting sources | ★☆☆☆☆ |
| Juices | 1 supporting sources | ★☆☆☆☆ |
| Oils | 1 supporting sources | ★☆☆☆☆ |
| Plant extracts | 1 supporting sources | ★☆☆☆☆ |
| Skin | 1 supporting sources | ★☆☆☆☆ |
Extracts
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Alcohol fractions
- Phytotherapy research : PTR
Aqueous-ethanolic extracts (30/70)
- Pakistan journal of pharmaceutical sciences
Extracts of cranberry fruit
- Journal of natural products
Fermented extract
- Phytotherapy research : PTR
Fruit juice
- Phytotherapy research : PTR
Juices
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Oils
- Phytotherapy research : PTR
Plant extracts
- Frontiers in microbiology
Skin
- Phytotherapy research : PTR