Uvaria dac

Uvaria dac · Accepted scientific name

Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆

Uvaria dac is a unique botanical species primarily recognized for the specific characteristics of its leaves. Scientific interest in this plant often focuses on the chemical potential found within its various plant extracts. Researchers frequently utilize chloroform extract to isolate and study the bioactive compounds housed within the foliage. These studies aim to uncover the therapeutic properties that make the species a subject of pharmacological importance. Understanding these botanical components is essential for exploring the full medicinal profile of the plant.

Quick facts
Synonyms
Uvaria Varaigneana
Common names
Not available
Family
Annonaceae
Distribution
Southern America
Plant Parts
Leaf

Classification

Synonyms

Uvaria dac is a botanical species that is sometimes identified by its synonym, Uvaria varaigneana. This nomenclatural connection highlights the evolving nature of taxonomic classifications within the plant kingdom. Researchers often encounter these dual names when studying the specific characteristics of this genus. Understanding these relationships is essential for maintaining accuracy in scientific databases and field guides. Consequently, recognizing both names ensures that botanists can consistently track the plant's distribution and study.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Uvaria dac belongs to the vast kingdom Plantae, representing the diverse life found within the botanical world. This specific species is classified under the class Equisetopsida and falls within the order Magnoliales. Within this taxonomic hierarchy, it is a distinguished member of the family Annonaceae. Furthermore, the plant is categorized under the genus Uvaria, highlighting its evolutionary connections. Understanding these biological relationships provides essential insight into the unique characteristics of Uvaria dac.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Magnoliales
Family Annonaceae
Genus Uvaria

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Uvaria dac is a plant species primarily concentrated within the diverse ecosystems of tropical Asia. Its natural distribution spans several key regions across the Indo-China peninsula. Specifically, this species can be found flourishing in the lush landscapes of Cambodia and Laos. It also maintains a presence throughout the territories of Thailand and Vietnam. Together, these locations define the core geographic range of this tropical flora.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Biological Activities

Compounds

Conditions

Uvaria dac contains bioactive compounds that demonstrate significant therapeutic potential against various pancreatic cancer cell lines. Specifically, the plant extract shows effectiveness in treating the Capan-1 cell line. It also exhibits strong preferential cytotoxicity against the KLM-1 line. Furthermore, Uvaria dac provides treatment capabilities for MIA PaCa-2 cells. Finally, the plant is shown to be effective against the PANC-1 and PSN-1 cell lines.

Preparations

Uvaria dac is utilized in scientific research through its preparation as various plant extracts. Specifically, the leaves of Uvaria dac are prepared as a chloroform extract to isolate highly oxygenated cyclohexene derivatives like uvaridacols I-L. These extracted compounds have demonstrated significant preferential cytotoxicity against several pancreatic cancer cell lines. Furthermore, Uvaria dac is processed as a plant extract that shows synergistic effects when combined with TRAIL to sensitize breast cancer cells. This plant extract also functions to suppress the phosphorylation of p65, which is a key mechanism in TRAIL resistance.

Parts used

Uvaria dac serves as a significant botanical source for the discovery of highly oxygenated antiausterity agents. Researchers have specifically focused on the plant's leaves to isolate unique chemical compounds through chloroform extraction. This process successfully yielded four new cyclohexene derivatives, known as uvaridacols I-L, alongside several previously documented substances. Through extensive spectroscopic analysis, scientists determined the complex structures of these newly identified molecules. Most notably, the compound uvaridacol L demonstrated potent cytotoxicity against various pancreatic cancer cell lines under nutrient-deprived conditions.