Cat's Claw

Uncaria tomentosa · Accepted scientific name

Scientific literature: Very Extensive (429 studies) · ★★★★★

Cat's Claw, scientifically known as Uncaria tomeentoa, is a legendary medicinal vine native to the Amazon rainforest. Renowned for its hooked thorns, this potent plant has been used for centuries in traditional healing to support immune function, reduce inflammation, and promote overall wellness through its rich antioxidant properties.

Family
Rubiaceae
Native range
Southern America
Parts used
Leaf
Common names
Cat'S-Claw · Cat'S Claw
Scientific synonyms
Ourouparia Tomentosa · Uncaria Tomentosa Var. Dioica · 6 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • Una de gato en el Parque Nacional Yanachaga-Chemillén
  • Nauclea surinamensis
  • Una de gato en el Parque Nacional Yanachaga Chemillén
  • Una de Gato
  • Uña de Gato
  • Nauclea tomentosa
  • Uña de gato en el Parque Nacional Yanachaga Chemillen
  • Ourouparia tomentosa
  • Una de gato en el Parque Nacional Yanachaga Chemillen
  • Uña de gato en el Parque Nacional Yanachaga-Chemillén
  • Nauclea aculeata
  • Uña de gato en el Parque Nacional Yanachaga Chemillén
  • Una de gato en el Parque Nacional Yanachaga-Chemillen
  • Uña de gato en el Parque Nacional Yanachaga-Chemillen
  • Cinchona globifSOPA DE MACACOera
  • Nauclea polycephaala
  • uña de gato

German:

  • Katzenkralle
  • Liane du Pérou
  • Katzenkralle

French:

  • liane du Pérou
  • griffe de chat
  • Uña de gato
  • Liane du Pérou

Scientific Names

Accepted name

Uncaria tomentosa

Synonyms

Taxonomical Classification

This plant, known scientifically as Uncaria tomentosa, belongs to the kingdom Plantae and the phylum Streptophyta. It is classified under the class Equisetopsida and subclass Magnoliidae within the order Gentianales. Finally, it is a member of the Rubiaceae family and falls under the genus Uncaria.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Gentianales WCVP
Family Rubiaceae WCVP
Genus Uncaria WCVP

Distribution

This plant is primarily found within the diverse tropical landscapes of Central America. Its natural habitat spans several countries, including Belize and Guatemala. It also flourishes throughout the lush rainforests of Honduras and Nicaragua. Additionally, the species can be located within the biological corridors of Costa Rica. Consequently, its distribution is concentrated across these specific Central American nations.

Region Area Source
Central America Belize WCVP
Central America Costa Rica WCVP
Central America Guatemala WCVP
Central America Honduras WCVP
Central America Nicaragua WCVP
Central America Panamá WCVP
Caribbean Trinidad-Tobago WCVP
Northern South America French Guiana WCVP
Northern South America Guyana WCVP
Northern South America Suriname WCVP

Plant Parts

This plant, commonly known as Cat's Claw, is a woody vine where various components hold significant importance in traditional medicine. The bark is the most widely utilized part, often harvested for its potent antioxidant and anti-inflammatory properties. While the leaves are sometimes studied for their chemical composition, the primary medicinal value is concentrated in the inner bark. Therefore, when preparing traditional remedies, practitioners focus on the therapeutic compounds found within the bark rather than the leaves.
Plant Part Sources Consensus
leaf Phytochemical analysis : PCA (and other 3 sources) ★★☆☆☆

Chemicals

Uncaria tomentosa has 59 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include Pteropodine, Isopteropodine, BETA-SITOSTEROL, CA, CAMPESTEROL.

Chemicals reported in Uncaria tomentosa
Chemical Supporting sources Consensus
Pteropodine 4 supporting sources ★★☆☆☆
Isopteropodine 3 supporting sources ★★☆☆☆
BETA-SITOSTEROL 2 supporting sources ★☆☆☆☆
CA 2 supporting sources ★☆☆☆☆
CAMPESTEROL 2 supporting sources ★☆☆☆☆
FE 2 supporting sources ★☆☆☆☆
ISOMITRAPHYLLINE 2 supporting sources ★☆☆☆☆
MG 2 supporting sources ★☆☆☆☆
MN 2 supporting sources ★☆☆☆☆
Mitraphylline 2 supporting sources ★☆☆☆☆

Pteropodine

  1. Dr. Duke
  2. Acta crystallographica. Section C, Crystal structure communications
  3. Phytochemistry
  4. European journal of pharmacology

Isopteropodine

  1. Dr. Duke
  2. Acta crystallographica. Section C, Crystal structure communications
  3. European journal of pharmacology

BETA-SITOSTEROL

  1. Dr. Duke
  2. Bollettino della Societa italiana di biologia sperimentale

CA

  1. Food chemistry
  2. Biological trace element research

CAMPESTEROL

  1. Dr. Duke
  2. Bollettino della Societa italiana di biologia sperimentale

FE

  1. Food chemistry
  2. Biological trace element research

ISOMITRAPHYLLINE

  1. Dr. Duke
  2. Phytochemistry

MG

  1. Food chemistry
  2. Biological trace element research

MN

  1. Food chemistry
  2. Biological trace element research

Mitraphylline

  1. Dr. Duke
  2. Planta medica

Activities

Uncaria tomentosa has 249 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Cytotoxic, Antibacterial, Anticancer, Antiinflammatory.

Most Reported Activities

Activity Sources Consensus
Antioxidant Dr. Duke (and other 6 sources) ★★★☆☆
Cytotoxic Dr. Duke (and other 3 sources) ★★☆☆☆
Antibacterial Dr. Duke (and other 2 sources) ★☆☆☆☆
Anticancer Dr. Duke (and other 2 sources) ★☆☆☆☆
Antiinflammatory Dr. Duke (and other 2 sources) ★☆☆☆☆
Antimutagenic Dr. Duke (and other 2 sources) ★☆☆☆☆
Mutagenic Dr. Duke (and other 2 sources) ★☆☆☆☆
(-)-Chronotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
5-HT-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
5-Lipoxygenase-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Uncaria tomentosa has 28 reported medicinal uses identified across 3 scientific publications and several other databases. The most consistently reported uses include arthritis, cancer, DNA damage, HIV, abscesses.

Most Reported Uses

Use Sources Consensus
arthritis Complementary therapies in clinical practice (and other 2 sources) ★☆☆☆☆
cancer Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
DNA damage Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) ★☆☆☆☆
HIV Journal of medical virology (and other 1 sources) ★☆☆☆☆
abscesses International journal of molecular sciences (and other 1 sources) ★☆☆☆☆
allergies International journal of molecular sciences (and other 1 sources) ★☆☆☆☆
asthma International journal of molecular sciences (and other 1 sources) ★☆☆☆☆
bladder cancer Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
fatigue Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) ★☆☆☆☆
fevers International journal of molecular sciences (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
Uncaria tomentosa extracts Anticancer research (and other 2 sources) ★☆☆☆☆
aqueous extract Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
extracts Journal of clinical medicine (and other 2 sources) ★☆☆☆☆
water extracts Anticancer research (and other 2 sources) ★☆☆☆☆
2% Uncaria tomentosa gel Journal of prosthodontics : official journal of the American College of Prosthodontists (and other 1 sources) ★☆☆☆☆
AEUt Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Aqueous extract of the bark Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Bark Products Antioxidants (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆
Micropulverized Uncaria tomentosa Brazilian oral research (and other 1 sources) ★☆☆☆☆
Samento Molecules (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆