Uncaria rhynchophylla ex
Uncaria rhynchophylla · Accepted scientific name
Scientific literature: Moderate (112 studies) · ★★★☆☆
Uncaria rhynchophylla ex, scientifically known as Uncaria rhynchophylla, is a significant medicinal climber belonging to the Rubiaceae family. Renowned for its bioactive alkaloids, this plant is widely utilized in traditional medicine to alleviate inflammation, support neurological health, and promote sleep, serving as a vital component in herbal pharmacology.
- Family
- Rubiaceae
- Native range
- Asia-Temperate
- Parts used
- Stem · Leaf
- Common names
- Not available
- Scientific synonyms
- Nauclea Rhynchophylla · Ourouparia Rhynchophylla · 1 more
Names
Regional and Traditional Names
Spanish:
- Nauclea rhynchophylla
- Uncaria rhynchophylla var. kouteng
- Ourouparia rhynchophylla
- Uncaria rhynchophylloides
French:
- Gou teng
- Uncaria rhyncophylla
Scientific Names
Accepted name
Uncaria rhynchophyllaSynonyms
- Nauclea rhynchophylla
- Ourouparia rhynchophylla
- Uncaria rhynchophylla var. kouteng
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and class Equisetopsida. It is further categorized under the subclass Magnoliidae and the order Gentianales, falling within the family Rubiaceae. Finally, its specific taxonomic identity is defined by the genus Uncaria.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Gentianales | WCVP |
| Family | Rubiaceae | WCVP |
| Genus | Uncaria | WCVP |
Distribution
This plant exhibits a broad geographical distribution across several key regions of East and Southeast Asia. In China, it can be found specifically throughout the South-Central and Southeast territories. Its presence extends further into Eastern Asia, where it is documented in both Japan and Taiwan. Additionally, the species is located within the Indo-China region, specifically in Vietnam. Together, these locations define the natural habitat range for Uncaria rhynchophylla.
| Region | Area | Source |
|---|---|---|
| China | China South-Central | WCVP |
| China | China Southeast | WCVP |
| Eastern Asia | Japan | WCVP |
| Eastern Asia | Taiwan | WCVP |
| Indo-China | Vietnam | WCVP |
Plant Parts
This plant, known scientifically as Uncaria rhynchophylla, exhibits specialized morphological features characteristic of its climbing nature. As a woody vine, it utilizes sharp, curved hooks to anchor itself and ascend toward the sunlight. The foliage consists of a lush green leaf structure that facilitates photosynthesis, while the long, climbing stems provide the necessary framework for growth. The overall architecture of the plant is supported by sturdy, elongated stems that weave through the forest canopy. Most importantly, for medicinal purposes, the stem bark is the primary part harvested, as it contains the concentrated bioactive alkaloids used in traditional and modern pharmacology.| Plant Part | Sources | Consensus |
|---|---|---|
| stem | Journal of separation science (and other 5 sources) | ★★★☆☆ |
| leaf | Journal of natural products (and other 4 sources) | ★★☆☆☆ |
| root | International journal of biological macromolecules (and other 2 sources) | ★☆☆☆☆ |
Chemicals
Uncaria rhynchophylla has 32 reported phytochemicals identified across 11 scientific publications and several other databases. The most consistently reported chemicals include Rhynchophylline, Corynoxeine, Isocorynoxeine, Flavonoids, Hirsuteine.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Rhynchophylline | 6 supporting sources | ★★★☆☆ |
| Corynoxeine | 4 supporting sources | ★★☆☆☆ |
| Isocorynoxeine | 3 supporting sources | ★★☆☆☆ |
| Flavonoids | 2 supporting sources | ★☆☆☆☆ |
| Hirsuteine | 2 supporting sources | ★☆☆☆☆ |
| Isorhynchophylline | 2 supporting sources | ★☆☆☆☆ |
| Strictosidine | 2 supporting sources | ★☆☆☆☆ |
| (E)-LINALOOL OXIDE | 1 supporting sources | ★☆☆☆☆ |
| As | 1 supporting sources | ★☆☆☆☆ |
| CATECHIN | 1 supporting sources | ★☆☆☆☆ |
Rhynchophylline
- Journal of pharmaceutical and biomedical analysis
- Journal of chromatographic science
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Drug metabolism and disposition: the biological fate of chemicals
- Acta pharmacologica Sinica
View 1 additional sources
- International journal of biological macromolecules
Corynoxeine
- Journal of pharmaceutical and biomedical analysis
- Journal of chromatographic science
- Drug metabolism and disposition: the biological fate of chemicals
- International journal of biological macromolecules
Isocorynoxeine
- Journal of pharmaceutical and biomedical analysis
- Journal of chromatographic science
- Drug metabolism and disposition: the biological fate of chemicals
Flavonoids
- Journal of ethnopharmacology
- European journal of mass spectrometry (Chichester, England)
Hirsuteine
- Journal of pharmaceutical and biomedical analysis
- Journal of ethnopharmacology
Isorhynchophylline
- Journal of chromatographic science
- International journal of biological macromolecules
Strictosidine
- Plant, cell & environment
- International journal of biological macromolecules
(E)-LINALOOL OXIDE
- Journal of oleo science
As
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
CATECHIN
- Journal of ethnopharmacology
Activities
Uncaria rhynchophylla has 6 reported activities identified across 11 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Neuroprotective, Antibacterial, Anticancer, Antihypertensive.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antioxidant | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| Neuroprotective | International journal of biological macromolecules (and other 2 sources) | ★☆☆☆☆ |
| Antibacterial | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Anticancer | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Antihypertensive | International journal of biological macromolecules (and other 1 sources) | ★☆☆☆☆ |
| Free-Radical Scavenging | Life sciences (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Uncaria rhynchophylla has 17 reported medicinal uses identified across 11 scientific publications and several other databases. The most consistently reported uses include Alzheimer's disease, cardiovascular diseases, Parkinson's disease, cancer, epilepsy.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| Alzheimer's disease | Acta pharmacologica Sinica (and other 3 sources) | ★★☆☆☆ |
| cardiovascular diseases | Journal of separation science (and other 3 sources) | ★★☆☆☆ |
| Parkinson's disease | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| cancer | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| epilepsy | Pakistan journal of pharmaceutical sciences (and other 2 sources) | ★☆☆☆☆ |
| hypertension | Journal of pharmaceutical and biomedical analysis (and other 2 sources) | ★☆☆☆☆ |
| neuroinflammation | Acta pharmacologica Sinica (and other 2 sources) | ★☆☆☆☆ |
| antihypertensive | International journal of biological macromolecules (and other 1 sources) | ★☆☆☆☆ |
| anxiety | CNS drugs (and other 1 sources) | ★☆☆☆☆ |
| cognitive impairments | Acta pharmacologica Sinica (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Gou-Teng | Journal of separation science (and other 2 sources) | ★☆☆☆☆ |
| "Ling-Jiao-Gou-Teng-Yin" | Journal of separation science (and other 1 sources) | ★☆☆☆☆ |
| "Tian-Ma-Gou-Teng-Yin" | Journal of separation science (and other 1 sources) | ★☆☆☆☆ |
| "Yi-Gan-San" | Journal of separation science (and other 1 sources) | ★☆☆☆☆ |
| 50% aqueous methanol extracts | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Alkaloid fraction | Neuroscience letters (and other 1 sources) | ★☆☆☆☆ |
| CHCl3 extract of the leaves of Uncaria rhynchophylla | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| Methanol extract | Life sciences (and other 1 sources) | ★☆☆☆☆ |
| U. rhyncophylla extracts | Journal of chromatographic science (and other 1 sources) | ★☆☆☆☆ |
| URP70-1 | International journal of biological macromolecules (and other 1 sources) | ★☆☆☆☆ |