Uncaria rhynchophylla ex
Uncaria rhynchophylla · Accepted scientific name
Scientific literature: Moderate (112 studies) · ★★★☆☆
Uncaria rhynchophylla ex, scientifically known as Uncaria rhynchophylla, is a significant medicinal climber belonging to the Rubiaceae family. Renowned for its bioactive alkaloids, this plant is widely utilized in traditional medicine to alleviate inflammation, support neurological health, and promote sleep, serving as a vital component in herbal pharmacology.
- Family
- Rubiaceae
- Native range
- Asia-Temperate
- Parts used
- Stem · Leaf
- Common names
- Not available
- Scientific synonyms
- Nauclea Rhynchophylla · Ourouparia Rhynchophylla · 1 more
Names and Synonyms
Scientific Names
Accepted name
Uncaria rhynchophyllaSynonyms
- Nauclea rhynchophylla
- Ourouparia rhynchophylla
- Uncaria rhynchophylla var. kouteng
Regional and Traditional Names
Spanish:
- Nauclea rhynchophylla
- Uncaria rhynchophylla var. kouteng
- Ourouparia rhynchophylla
- Uncaria rhynchophylloides
French:
- Gou teng
- Uncaria rhyncophylla
Sources: Wikidata
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and class Equisetopsida. It is further categorized under the subclass Magnoliidae and the order Gentianales, falling within the family Rubiaceae. Finally, its specific taxonomic identity is defined by the genus Uncaria.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Gentianales |
| Family | Rubiaceae |
| Genus | Uncaria |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a broad geographical distribution across several key regions of East and Southeast Asia. In China, it can be found specifically throughout the South-Central and Southeast territories. Its presence extends further into Eastern Asia, where it is documented in both Japan and Taiwan. Additionally, the species is located within the Indo-China region, specifically in Vietnam. Together, these locations define the natural habitat range for Uncaria rhynchophylla.
| Region | Area |
|---|---|
| China | China South-Central |
| China | China Southeast |
| Eastern Asia | Japan |
| Eastern Asia | Taiwan |
| Indo-China | Vietnam |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Uncaria rhynchophylla is characterized by its specialized growth habit as a woody climber, primarily classified under the life form categories of phanerophyte and nanophanerophyte. As a phanerophyte, its perennial reproductive organs and vegetative structures are elevated above the soil surface, typically supported by the structural framework of surrounding trees in its tropical forest habitat. This climbing strategy allows the plant to navigate the vertical strata of the ecosystem, transitioning from a nanophanerophyte state in its earlier, more compact developmental stages to a more robust, climbing woody vine. Its life cycle is sustained through continuous vegetative growth and seasonal reproductive cycles, utilizing its climbing mechanism to access sunlight in the canopy, which is essential for its long-term survival and maturation within competitive forest environments.
- Life form :
- phanerophyte
Morphology
The morphology of Uncaria rhynchophylla is characterized by its growth as a liana, functioning as an obligatory climber that utilizes external structures for support rather than being self-supporting. While it can exhibit characteristics associated with a shrub or tree-like form in certain developmental stages or contexts, its primary structural habit is that of a woody vine. The plant is an independent organism, meaning it does not function as a parasite, and it maintains a terrestrial existence rather than living as an epiphyte. The woodiness of the species is considered variable, reflecting its adaptation to its climbing lifestyle as it transitions from younger, more flexible shoots to more robust, lignified stems.
- Climber :
- liana
- Climber :
- obligatory
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Growth form :
- shrub
- Parasite :
- independent
- Woodiness :
- variable
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Uncaria rhynchophylla has 3 reported plant parts identified across 11 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include stem, leaf, root.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Stem | 5 supporting sources | ★★★☆☆ |
| Leaf | 4 supporting sources | ★★☆☆☆ |
| Root | 2 supporting sources | ★☆☆☆☆ |
Stem
- Journal of separation science
- Bioorganic chemistry
- Biomolecules
- Chinese journal of natural medicines
- International journal of biological macromolecules
Leaf
- Journal of natural products
- Bioorganic chemistry
- Biomolecules
- International journal of biological macromolecules
Root
- International journal of biological macromolecules
- Biomolecules
Chemicals
Uncaria rhynchophylla has 32 reported phytochemicals identified across 11 scientific publications and several other databases. The most consistently reported chemicals include Rhynchophylline, Corynoxeine, Isocorynoxeine, Flavonoids, Hirsuteine.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Rhynchophylline | 6 supporting sources | ★★★☆☆ |
| Corynoxeine | 4 supporting sources | ★★☆☆☆ |
| Isocorynoxeine | 3 supporting sources | ★★☆☆☆ |
| Flavonoids | 2 supporting sources | ★☆☆☆☆ |
| Hirsuteine | 2 supporting sources | ★☆☆☆☆ |
| Isorhynchophylline | 2 supporting sources | ★☆☆☆☆ |
| Strictosidine | 2 supporting sources | ★☆☆☆☆ |
| (E)-LINALOOL OXIDE | 1 supporting sources | ★☆☆☆☆ |
| As | 1 supporting sources | ★☆☆☆☆ |
| CATECHIN | 1 supporting sources | ★☆☆☆☆ |
Rhynchophylline
- Journal of pharmaceutical and biomedical analysis
- Journal of chromatographic science
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Drug metabolism and disposition: the biological fate of chemicals
- Acta pharmacologica Sinica
View 1 additional sources
- International journal of biological macromolecules
Corynoxeine
- Journal of pharmaceutical and biomedical analysis
- Journal of chromatographic science
- Drug metabolism and disposition: the biological fate of chemicals
- International journal of biological macromolecules
Isocorynoxeine
- Journal of pharmaceutical and biomedical analysis
- Journal of chromatographic science
- Drug metabolism and disposition: the biological fate of chemicals
Flavonoids
- Journal of ethnopharmacology
- European journal of mass spectrometry (Chichester, England)
Hirsuteine
- Journal of pharmaceutical and biomedical analysis
- Journal of ethnopharmacology
Isorhynchophylline
- Journal of chromatographic science
- International journal of biological macromolecules
Strictosidine
- Plant, cell & environment
- International journal of biological macromolecules
(E)-LINALOOL OXIDE
- Journal of oleo science
As
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
CATECHIN
- Journal of ethnopharmacology
Activities
Uncaria rhynchophylla has 6 reported activities identified across 11 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Neuroprotective, Antibacterial, Anticancer, Antihypertensive.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Neuroprotective | 2 supporting sources | ★☆☆☆☆ |
| Antibacterial | 1 supporting sources | ★☆☆☆☆ |
| Anticancer | 1 supporting sources | ★☆☆☆☆ |
| Antihypertensive | 1 supporting sources | ★☆☆☆☆ |
| Free-Radical Scavenging | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Journal of ethnopharmacology
- BMC complementary and alternative medicine
Neuroprotective
- International journal of biological macromolecules
- Journal of ethnopharmacology
Antibacterial
- Journal of ethnopharmacology
Anticancer
- Journal of ethnopharmacology
Antihypertensive
- International journal of biological macromolecules
Free-Radical Scavenging
- Life sciences
Conditions
Uncaria rhynchophylla has 17 reported investigations on conditions identified across 11 scientific publications and several other databases. The most consistently reported conditions include Alzheimer's disease, cardiovascular diseases, Parkinson's disease, cancer, epilepsy.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Alzheimer's disease | 3 supporting sources | ★★☆☆☆ |
| Cardiovascular diseases | 3 supporting sources | ★★☆☆☆ |
| Parkinson's disease | 2 supporting sources | ★☆☆☆☆ |
| Cancer | 2 supporting sources | ★☆☆☆☆ |
| Epilepsy | 2 supporting sources | ★☆☆☆☆ |
| Hypertension | 2 supporting sources | ★☆☆☆☆ |
| Neuroinflammation | 2 supporting sources | ★☆☆☆☆ |
| Antihypertensive | 1 supporting sources | ★☆☆☆☆ |
| Anxiety | 1 supporting sources | ★☆☆☆☆ |
| Cognitive impairments | 1 supporting sources | ★☆☆☆☆ |
Alzheimer's disease
- Acta pharmacologica Sinica
- Journal of ethnopharmacology
- International journal of biological macromolecules
Cardiovascular diseases
- Journal of separation science
- Journal of ethnopharmacology
- European journal of mass spectrometry (Chichester, England)
Parkinson's disease
- Journal of ethnopharmacology
- International journal of biological macromolecules
Cancer
- Journal of ethnopharmacology
- Phytotherapy research : PTR
Epilepsy
- Pakistan journal of pharmaceutical sciences
- Life sciences
Hypertension
- Journal of pharmaceutical and biomedical analysis
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Neuroinflammation
- Acta pharmacologica Sinica
- Journal of ethnopharmacology
Antihypertensive
- International journal of biological macromolecules
Anxiety
- CNS drugs
Cognitive impairments
- Acta pharmacologica Sinica
Preparations
Uncaria rhynchophylla has 16 reported preparations identified across 11 scientific publications and several other databases. The most consistently reported preparations include Gou-Teng, "Ling-Jiao-Gou-Teng-Yin", "Tian-Ma-Gou-Teng-Yin", "Yi-Gan-San", 50% aqueous methanol extracts.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Gou-teng | 2 supporting sources | ★☆☆☆☆ |
| "ling-jiao-gou-teng-yin" | 1 supporting sources | ★☆☆☆☆ |
| "tian-ma-gou-teng-yin" | 1 supporting sources | ★☆☆☆☆ |
| "yi-gan-san" | 1 supporting sources | ★☆☆☆☆ |
| 50% aqueous methanol extracts | 1 supporting sources | ★☆☆☆☆ |
| Alkaloid fraction | 1 supporting sources | ★☆☆☆☆ |
| Chcl3 extract of the leaves of uncaria rhynchophylla | 1 supporting sources | ★☆☆☆☆ |
| Methanol extract | 1 supporting sources | ★☆☆☆☆ |
| U. rhyncophylla extracts | 1 supporting sources | ★☆☆☆☆ |
| Urp70-1 | 1 supporting sources | ★☆☆☆☆ |
Gou-teng
- Journal of separation science
- BMC genomics
"ling-jiao-gou-teng-yin"
- Journal of separation science
"tian-ma-gou-teng-yin"
- Journal of separation science
"yi-gan-san"
- Journal of separation science
50% aqueous methanol extracts
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Alkaloid fraction
- Neuroscience letters
Chcl3 extract of the leaves of uncaria rhynchophylla
- Journal of natural products
Methanol extract
- Life sciences
U. rhyncophylla extracts
- Journal of chromatographic science
Urp70-1
- International journal of biological macromolecules