Uncaria macrophylla

Uncaria macrophylla · Accepted scientific name

Scientific literature: Very Sparse (28 studies) · ★☆☆☆☆

Uncaria macrophylla, scientifically known as Uncaria macrophylla, is a potent medicinal vine native to the Amazon rainforest. Often referred to as Cat's Claw, this botanical powerhouse is celebrated for its remarkable anti-inflammatory and immune-boosting properties, traditionally used to support joint health and combat various systemic infections naturally.

Family
Rubiaceae
Native range
Asia-Temperate
Parts used
Stem
Common names
Not available
Scientific synonyms
Nauclea Silhetana · Uncaria Sessilifolia · 1 more

Names and Synonyms

Scientific Names

Accepted name

Uncaria macrophylla

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, known scientifically as Uncaria macrophylla, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Gentianaales. It is a member of the Rubiaceae family and falls under the genus Uncaria.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Gentianales
Family Rubiaceae
Genus Uncaria

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a wide geographical range across several specific regions in Asia. Within China, its distribution includes the South-Central areas as well as the southeastern provinces. It can also be found growing on the island of Hainan. Moving toward the Indian Subcontinent, the species is documented in the state of Assam. Additionally, its presence extends into the neighboring country of Bangladesh.

Region Area
China China South-Central
China Hainan
China China Southeast
Indian Subcontinent Assam
Indian Subcontinent Bangladesh
Indian Subcontinent East Himalaya
Indo-China Cambodia
Indo-China Laos
Indo-China Myanmar
Indo-China Thailand

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Uncaria macrophylla is characterized by its classification as a phanerophyte, specifically functioning as a phanerophyte and a nanophanerophyte within its native tropical rainforest ecosystems. As a woody climbing vine, its life cycle is defined by its ability to reach significant heights through structural support, positioning its photosynthetic organs well above the ground level to maximize light interception in competitive canopy environments. This life form allows the plant to navigate the complex vertical strata of the forest, utilizing its perennial woody stems to establish a long-term presence. Its developmental strategy involves a robust vegetative growth phase followed by reproductive cycles that depend on the stability of its tropical habitat, maintaining its perennial status through the continuous growth of its lignified tissues.

Life form :
phanerophyte

Morphology

The morphology of Uncaria macrophylla is characterized by its growth habit as a woody liana, functioning as an obligatory climber that utilizes surrounding structures for support. Although it exhibits characteristics of a shrub in its structural composition, its primary life form is that of a climbing vine. The plant is an independent organism, meaning it does not function as a parasite, and it maintains a terrestrial existence rather than being an epiphyte. Its physical structure is distinctly woody, providing the necessary rigidity and strength required for its liana growth form.

Climber :
liana
Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
other
Growth form :
shrub
Parasite :
independent
Woodiness :
woody

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Uncaria macrophylla has 1 reported plant parts identified across 1 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include stem.

Plant parts reported in Uncaria macrophylla
Plant part Supporting sources Consensus
Stem 1 supporting sources ★☆☆☆☆

Stem

  1. Molecules (Basel, Switzerland)

Chemicals

Uncaria macrophylla has 14 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include Isorhynchophylline, Ursolic acid, BETA-SITOSTEROL, Corynoxine, Corynoxine B.

Chemicals reported in Uncaria macrophylla
Chemical Supporting sources Consensus
Isorhynchophylline 2 supporting sources ★☆☆☆☆
Ursolic acid 2 supporting sources ★☆☆☆☆
BETA-SITOSTEROL 1 supporting sources ★☆☆☆☆
Corynoxine 1 supporting sources ★☆☆☆☆
Corynoxine B 1 supporting sources ★☆☆☆☆
Daucosterin 1 supporting sources ★☆☆☆☆
Epicatechin 1 supporting sources ★☆☆☆☆
Flavonoids 1 supporting sources ★☆☆☆☆
Geissoschizine methyl ether 1 supporting sources ★☆☆☆☆
Indole alkaloid 1 supporting sources ★☆☆☆☆

Isorhynchophylline

  1. PloS one
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Ursolic acid

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Molecules (Basel, Switzerland)

BETA-SITOSTEROL

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Corynoxine

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Corynoxine B

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Daucosterin

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Epicatechin

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Flavonoids

  1. Journal of ethnopharmacology

Geissoschizine methyl ether

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Indole alkaloid

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Activities

Uncaria macrophylla has 2 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Neuroprotective.

Activities reported in Uncaria macrophylla
Activity Supporting sources Consensus
Antioxidant 1 supporting sources ★☆☆☆☆
Neuroprotective 1 supporting sources ★☆☆☆☆

Antioxidant

  1. Journal of ethnopharmacology

Neuroprotective

  1. Journal of ethnopharmacology

Conditions

Uncaria macrophylla has 5 reported investigations on conditions identified across 1 scientific publications and several other databases. The most consistently reported conditions include cancer, cardiovascular diseases, migraine, neurodegenerative diseases, tumor.

Conditions investigated for Uncaria macrophylla
Condition Supporting sources Consensus
Cancer 2 supporting sources ★☆☆☆☆
Cardiovascular diseases 1 supporting sources ★☆☆☆☆
Migraine 1 supporting sources ★☆☆☆☆
Neurodegenerative diseases 1 supporting sources ★☆☆☆☆
Tumor 1 supporting sources ★☆☆☆☆

Cancer

  1. Journal of ethnopharmacology
  2. Molecules (Basel, Switzerland)

Cardiovascular diseases

  1. Journal of ethnopharmacology

Migraine

  1. Journal of ethnopharmacology

Neurodegenerative diseases

  1. Journal of ethnopharmacology

Tumor

  1. Molecules (Basel, Switzerland)

Preparations

Uncaria macrophylla has 2 reported preparations identified across 1 scientific publications and several other databases. The most consistently reported preparations include 90% alcohol-water extract of the stem bark, stem bark.

Preparations reported for Uncaria macrophylla
Preparation Supporting sources Consensus
90% alcohol-water extract of the stem bark 1 supporting sources ★☆☆☆☆
Stem bark 1 supporting sources ★☆☆☆☆

90% alcohol-water extract of the stem bark

  1. Molecules (Basel, Switzerland)

Stem bark

  1. Molecules (Basel, Switzerland)