Uncaria macrophylla
Uncaria macrophylla · Accepted scientific name
Scientific literature: Very Sparse (28 studies) · ★☆☆☆☆
Uncaria macrophylla, scientifically known as Uncaria macrophylla, is a potent medicinal vine native to the Amazon rainforest. Often referred to as Cat's Claw, this botanical powerhouse is celebrated for its remarkable anti-inflammatory and immune-boosting properties, traditionally used to support joint health and combat various systemic infections naturally.
- Family
- Rubiaceae
- Native range
- Asia-Temperate
- Parts used
- Stem
- Common names
- Not available
- Scientific synonyms
- Nauclea Silhetana · Uncaria Sessilifolia · 1 more
Names and Synonyms
Scientific Names
Accepted name
Uncaria macrophyllaSynonyms
- Nauclea silhetana
- Uncaria sessilifolia
- Uruparia macrophylla
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant, known scientifically as Uncaria macrophylla, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Gentianaales. It is a member of the Rubiaceae family and falls under the genus Uncaria.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Gentianales |
| Family | Rubiaceae |
| Genus | Uncaria |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a wide geographical range across several specific regions in Asia. Within China, its distribution includes the South-Central areas as well as the southeastern provinces. It can also be found growing on the island of Hainan. Moving toward the Indian Subcontinent, the species is documented in the state of Assam. Additionally, its presence extends into the neighboring country of Bangladesh.
| Region | Area |
|---|---|
| China | China South-Central |
| China | Hainan |
| China | China Southeast |
| Indian Subcontinent | Assam |
| Indian Subcontinent | Bangladesh |
| Indian Subcontinent | East Himalaya |
| Indo-China | Cambodia |
| Indo-China | Laos |
| Indo-China | Myanmar |
| Indo-China | Thailand |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Uncaria macrophylla is characterized by its classification as a phanerophyte, specifically functioning as a phanerophyte and a nanophanerophyte within its native tropical rainforest ecosystems. As a woody climbing vine, its life cycle is defined by its ability to reach significant heights through structural support, positioning its photosynthetic organs well above the ground level to maximize light interception in competitive canopy environments. This life form allows the plant to navigate the complex vertical strata of the forest, utilizing its perennial woody stems to establish a long-term presence. Its developmental strategy involves a robust vegetative growth phase followed by reproductive cycles that depend on the stability of its tropical habitat, maintaining its perennial status through the continuous growth of its lignified tissues.
- Life form :
- phanerophyte
Morphology
The morphology of Uncaria macrophylla is characterized by its growth habit as a woody liana, functioning as an obligatory climber that utilizes surrounding structures for support. Although it exhibits characteristics of a shrub in its structural composition, its primary life form is that of a climbing vine. The plant is an independent organism, meaning it does not function as a parasite, and it maintains a terrestrial existence rather than being an epiphyte. Its physical structure is distinctly woody, providing the necessary rigidity and strength required for its liana growth form.
- Climber :
- liana
- Climber :
- obligatory
- Epiphyte :
- terrestrial
- Growth form :
- other
- Growth form :
- shrub
- Parasite :
- independent
- Woodiness :
- woody
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Uncaria macrophylla has 1 reported plant parts identified across 1 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include stem.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Stem | 1 supporting sources | ★☆☆☆☆ |
Stem
- Molecules (Basel, Switzerland)
Chemicals
Uncaria macrophylla has 14 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include Isorhynchophylline, Ursolic acid, BETA-SITOSTEROL, Corynoxine, Corynoxine B.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Isorhynchophylline | 2 supporting sources | ★☆☆☆☆ |
| Ursolic acid | 2 supporting sources | ★☆☆☆☆ |
| BETA-SITOSTEROL | 1 supporting sources | ★☆☆☆☆ |
| Corynoxine | 1 supporting sources | ★☆☆☆☆ |
| Corynoxine B | 1 supporting sources | ★☆☆☆☆ |
| Daucosterin | 1 supporting sources | ★☆☆☆☆ |
| Epicatechin | 1 supporting sources | ★☆☆☆☆ |
| Flavonoids | 1 supporting sources | ★☆☆☆☆ |
| Geissoschizine methyl ether | 1 supporting sources | ★☆☆☆☆ |
| Indole alkaloid | 1 supporting sources | ★☆☆☆☆ |
Isorhynchophylline
- PloS one
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Ursolic acid
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Molecules (Basel, Switzerland)
BETA-SITOSTEROL
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Corynoxine
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Corynoxine B
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Daucosterin
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Epicatechin
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Flavonoids
- Journal of ethnopharmacology
Geissoschizine methyl ether
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Indole alkaloid
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Activities
Uncaria macrophylla has 2 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Neuroprotective.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 1 supporting sources | ★☆☆☆☆ |
| Neuroprotective | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Journal of ethnopharmacology
Neuroprotective
- Journal of ethnopharmacology
Conditions
Uncaria macrophylla has 5 reported investigations on conditions identified across 1 scientific publications and several other databases. The most consistently reported conditions include cancer, cardiovascular diseases, migraine, neurodegenerative diseases, tumor.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Cancer | 2 supporting sources | ★☆☆☆☆ |
| Cardiovascular diseases | 1 supporting sources | ★☆☆☆☆ |
| Migraine | 1 supporting sources | ★☆☆☆☆ |
| Neurodegenerative diseases | 1 supporting sources | ★☆☆☆☆ |
| Tumor | 1 supporting sources | ★☆☆☆☆ |
Cancer
- Journal of ethnopharmacology
- Molecules (Basel, Switzerland)
Cardiovascular diseases
- Journal of ethnopharmacology
Migraine
- Journal of ethnopharmacology
Neurodegenerative diseases
- Journal of ethnopharmacology
Tumor
- Molecules (Basel, Switzerland)
Preparations
Uncaria macrophylla has 2 reported preparations identified across 1 scientific publications and several other databases. The most consistently reported preparations include 90% alcohol-water extract of the stem bark, stem bark.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| 90% alcohol-water extract of the stem bark | 1 supporting sources | ★☆☆☆☆ |
| Stem bark | 1 supporting sources | ★☆☆☆☆ |
90% alcohol-water extract of the stem bark
- Molecules (Basel, Switzerland)
Stem bark
- Molecules (Basel, Switzerland)