Chinese snake gourd

Trichosanthes kirilowii · Accepted scientific name

Scientific literature: Very Extensive (242 studies) · ★★★★★

Chinese snake gourd, scientifically known as Trichosanthes kirilowii, is a traditional medicinal plant revered in East Asian herbalism. Characterized by its elongated, vine-grown fruit, it is widely utilized for its cooling properties. It is frequently employed to treat inflammation, promote digestion, and support overall detoxification within holistic wellness practices.

Family
Cucurbitaceae
Native range
Asia-Temperate
Parts used
Root · Leaf
Common names
Chinese Snake Gourd · Chinese-Cucumber · 1 more
Scientific synonyms
Trichosanthes Japonica · Trichosanthes Kirilowii Var. Japonica · 8 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Trichosanthes kirilowii

Synonyms

Regional and Traditional Names

Spanish:

  • Trichosanthes obtusiloba
  • Trichosanthes japonica

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Cucurbitales and the family Cucurbitaceae, it is classified under the genus Trichosanthes. Specifically, the species is identified as Trichosanthes kirilowii.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Cucurbitales
Family Cucurbitaceae
Genus Trichosanthes

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a broad geographical distribution across several distinct regions of Asia and Europe. In the Caucasus, its presence is specifically noted within the North Caucasus region. Its range extends significantly into China, where it can be found in Inner Mongolia, China North-Central, and China Southeast. Furthermore, the species is also established within Eastern Asia, specifically in Japan. Consequently, these locations highlight the diverse environmental settings where the plant thrives.

Region Area
Caucasus North Caucasus
China Inner Mongolia
China China North-Central
China China Southeast
Eastern Asia Japan
Eastern Asia Korea
Eastern Asia Nansei-shoto
Indo-China Cambodia
Indo-China Laos
Indo-China Vietnam

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Morphology

The morphology of Trichosanthes kirilowii is characterized by its growth form as a herb, exhibiting a non-woody structure throughout its vegetative organs. It functions as an obligatory climber, utilizing specialized structures to ascend and navigate its environment.

Climber :
obligatory
Growth form :
herb
Woodiness :
non-woody

Reproduction

The reproduction of Trichosanthes kirilowii is characterized by the production of fleshy fruits, which serve as the primary vessel for its reproductive components. Within these fruits, the seeds exhibit highly consistent physical dimensions, maintaining a uniform seed volume of exactly 150 mm³. The mass of these seeds is equally standardized, with a measured mean, minimum, and maximum mass all recorded at 0.13925 g. This consistency in both volume and mass suggests a highly regulated developmental process during the maturation of the seeds within the fleshy fruit structure.

Fruit dryness :
fleshy
Seed mass mean:
0.13925 g
Seed volume max:
150 mm³

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Trichosanthes kirilowii has 4 reported plant parts identified across 19 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf, seed, fruit.

Plant parts reported in Trichosanthes kirilowii
Plant part Supporting sources Consensus
Root 14 supporting sources ★★★★★
Leaf 2 supporting sources ★☆☆☆☆
Seed 2 supporting sources ★☆☆☆☆
Fruit 1 supporting sources ★☆☆☆☆

Root

  1. Journal of ethnopharmacology
  2. Transplantation proceedings
  3. Toxicon : official journal of the International Society on Toxinology
  4. Biological & pharmaceutical bulletin
  5. International journal of biological macromolecules
View 9 additional sources
  1. Sheng wu gong cheng xue bao = Chinese journal of biotechnology
  2. Science in China. Series B, Chemistry, life sciences & earth sciences
  3. International journal of peptide and protein research
  4. Oncology reports
  5. Analytical biochemistry
  6. Life sciences
  7. Journal of biotechnology
  8. Immunopharmacology and immunotoxicology
  9. Planta medica

Leaf

  1. Sheng wu gong cheng xue bao = Chinese journal of biotechnology
  2. Journal of biotechnology

Seed

  1. Zeitschrift fur Naturforschung. C, Journal of biosciences
  2. Journal of natural products

Fruit

  1. The American journal of Chinese medicine

Chemicals

Trichosanthes kirilowii has 61 reported phytochemicals identified across 19 scientific publications and several other databases. The most consistently reported chemicals include Cucurbitacin B, Bryonolic acid, Flavonoids, Saponins, galactose.

Chemicals reported in Trichosanthes kirilowii
Chemical Supporting sources Consensus
Cucurbitacin B 4 supporting sources ★★☆☆☆
Bryonolic acid 2 supporting sources ★☆☆☆☆
Flavonoids 2 supporting sources ★☆☆☆☆
Saponins 2 supporting sources ★☆☆☆☆
galactose 2 supporting sources ★☆☆☆☆
glucose 2 supporting sources ★☆☆☆☆
glutamine 2 supporting sources ★☆☆☆☆
linoleic acid 2 supporting sources ★☆☆☆☆
oleic acid 2 supporting sources ★☆☆☆☆
palmitic acid 2 supporting sources ★☆☆☆☆

Cucurbitacin B

  1. PloS one
  2. Frontiers in plant science
  3. Journal of natural products
  4. Journal of ethnopharmacology

Bryonolic acid

  1. Biological & pharmaceutical bulletin
  2. Cellular and molecular biology (Noisy-le-Grand, France)

Flavonoids

  1. Frontiers in plant science
  2. Natural product research

Saponins

  1. Dr. Duke
  2. Journal of ethnopharmacology

galactose

  1. Zeitschrift fur Naturforschung. C, Journal of biosciences
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

glucose

  1. Zeitschrift fur Naturforschung. C, Journal of biosciences
  2. Molecules (Basel, Switzerland)

glutamine

  1. PloS one
  2. Journal of ethnopharmacology

linoleic acid

  1. Dr. Duke
  2. Zeitschrift fur Naturforschung. C, Journal of biosciences

oleic acid

  1. Dr. Duke
  2. Zeitschrift fur Naturforschung. C, Journal of biosciences

palmitic acid

  1. Zeitschrift fur Naturforschung. C, Journal of biosciences
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Activities

Trichosanthes kirilowii has 89 reported activities identified across 19 scientific publications and several other databases. The most consistently reported activities include Abortifacient, Antitumor, 5-Alpha-Reductase-Inhibitor, Allergenic, Alpha-Reductase-Inhibitor.

Activities reported in Trichosanthes kirilowii
Activity Supporting sources Consensus
Abortifacient 7 supporting sources ★★★★☆
Antitumor 4 supporting sources ★★☆☆☆
5-Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Allergenic 1 supporting sources ★☆☆☆☆
Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Androgenic 1 supporting sources ★☆☆☆☆
Anemiagenic 1 supporting sources ★☆☆☆☆
Angiogenic 1 supporting sources ★☆☆☆☆
Anorexic 1 supporting sources ★☆☆☆☆
AntiAIDS 1 supporting sources ★☆☆☆☆

Abortifacient

  1. Dr. Duke
  2. Transplantation proceedings
  3. Toxicon : official journal of the International Society on Toxinology
  4. International journal of peptide and protein research
  5. Scientia Sinica
View 2 additional sources
  1. Biological & pharmaceutical bulletin
  2. General pharmacology

Antitumor

  1. Dr. Duke
  2. Frontiers in plant science
  3. Current medicinal chemistry
  4. General pharmacology

5-Alpha-Reductase-Inhibitor

  1. Dr. Duke

Allergenic

  1. Dr. Duke

Alpha-Reductase-Inhibitor

  1. Dr. Duke

Androgenic

  1. Dr. Duke

Anemiagenic

  1. Dr. Duke

Angiogenic

  1. Dr. Duke

Anorexic

  1. Dr. Duke

AntiAIDS

  1. Dr. Duke

Medicinal Uses

Trichosanthes kirilowii has 30 reported medicinal uses identified across 19 scientific publications and several other databases. The most consistently reported uses include choriocarcinoma, HIV, heat, hydatidiform mole, inflammation.

Most Reported Uses

Use Sources Consensus
choriocarcinoma Plant cell reports (and other 3 sources) ★★☆☆☆
HIV Current HIV research (and other 2 sources) ★☆☆☆☆
heat Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
hydatidiform mole Toxicon : official journal of the International Society on Toxinology (and other 2 sources) ★☆☆☆☆
inflammation Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
invasive mole Toxicon : official journal of the International Society on Toxinology (and other 2 sources) ★☆☆☆☆
AIDS Proceedings of the National Academy of Sciences of the United States of America (and other 1 sources) ★☆☆☆☆
breast tumor Biomedical chromatography : BMC (and other 1 sources) ★☆☆☆☆
cancer Fitoterapia (and other 1 sources) ★☆☆☆☆
cardiac failure Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
root tubers Toxicon : official journal of the International Society on Toxinology (and other 2 sources) ★☆☆☆☆
Chinese folk medicine Life sciences (and other 1 sources) ★☆☆☆☆
Isolated compounds like bryonolic acid Cellular and molecular biology (Noisy-le-Grand, France) (and other 1 sources) ★☆☆☆☆
Tianhuafen Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology (and other 1 sources) ★☆☆☆☆
aqueous extracts Life sciences (and other 1 sources) ★☆☆☆☆
dried root Analytical biochemistry (and other 1 sources) ★☆☆☆☆
dried root tuber Biological & pharmaceutical bulletin (and other 1 sources) ★☆☆☆☆
ethanol extracts Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
extract Transplantation proceedings (and other 1 sources) ★☆☆☆☆
methanol extracts Genes & nutrition (and other 1 sources) ★☆☆☆☆