Toona sureni

What's the taxonomical classification of Toona sureni?

Toona sureni belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is situated in the class Equisetopsida and the subclass Magnoliidae. Following the taxonomic hierarchy further, it is placed in the order Sapindales and belongs to the family Meliaceae. Finally, the plant is categorized under the genus Toona, with its specific designation being the species sureni.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Meliaceae
Genus Toona
Species sureni
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Toona sureni has pinnately compound leaves characterized by a central rachis with numerous pairs of leaflets that exhibit an elliptical or lanceolate shape and serrated margins. The leaflets typically possess an acute apex and a cuneate base, contributing to a lush, feathery canopy appearance. The tree displays a robust woody stem with a thick, fissured bark that becomes more textured as the specimen matures. Its reproductive structures consist of small, inconspicuous flowers that eventually develop into fleshy drupes. These morphological features are essential for distinguishing the species within its specific ecological niche.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the tropical and subtropical regions of South Asia, specifically spanning across India, Nepal, Bangladesh, and parts of Southeast Asia. It thrives primarily in moist deciduous forests and riverine ecosystems where water availability is consistent. The species is often found in low-elevation areas characterized by heavy rainfall and humid climates. Its distribution is closely tied to specific soil types found along river banks and seasonal floodplains. These environmental requirements limit its natural occurrence to certain localized ecological niches within its broad range.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant, commonly known as the Indian Rosewood, is cultivated in tropical and subtropical climates by planting seeds or saplings in well-draining, nutrient-rich soils.

It requires full sunlight and consistent moisture to establish a strong root system during its early growth stages. Once mature, the species thrives in warm environments and is often grown for its high-quality timber and medicinal properties. Regular pruning and protection from extreme frost are essential practices to ensure healthy development and long-term survival.

Farmers typically manage these trees in agroforestry systems to maximize both ecological benefits and economic returns.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant, Toona sureni, utilizes its leaves, bark, and roots for various medicinal applications. The leaves are frequently prepared as decoctions or poultices to treat skin inflammations and minor wounds. Bark extracts are often employed to address digestive issues and respiratory ailments. Additionally, the roots contain specific bioactive compounds used in traditional remedies to reduce fever. These different components provide a diverse range of therapeutic properties for treating various ailments.

According to a study published by "Virology journal", Toona sureni leaves (TSL) were identified as showing antiviral activities against hepatitis C virus. The ethanol extracts of TSL demonstrated 50% inhibitory concentrations (IC50) of 13.9 μg/ml against the HCV J6/JFH1-P47 strain. Additionally, these leaves exhibited an IC50 of 2.0 μg/ml against the -P1 strain. TSL inhibited all of 11 HCV strains of all the genotypes tested to the same extent. These findings suggest that the leaves of Toona sureni may be a good candidate for the development of anti-HCV drugs.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaf
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, known as Toona sureni, has been historically utilized in traditional Ayurvedic and folk medicine systems across South Asia to treat various ailments such as skin diseases, wounds, and digestive disorders.

Practitioners often prepare decoctions or pastes from its leaves and bark to apply topically for inflammatory conditions. In many rural communities, the plant is also valued for its antimicrobial properties and is used to promote wound healing. Its roots have been integrated into local remedies to manage fever and other febrile illnesses.

These long-standing cultural practices highlight the botanical's significant role in historical primary healthcare.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Toona sureni?

This plant has antiviral properties and demonstrates significant heme polymerization inhibition activity. These specific pharmacological characteristics suggest that the plant contains bioactive compounds capable of interfering with viral replication cycles. The ability to inhibit heme polymerization indicates potential applications in managing conditions related to oxidative stress or certain blood disorders. Researchers investigate these biochemical pathways to determine how the plant's extracts might serve as templates for new drug development. Such diverse medicinal activities highlight the therapeutic potential of the species in modern pharmacology.

According to a study published by "Virology journal", Toona sureni leaves (TSL) showed antiviral activities against hepatitis C virus (HCV). The ethanol extracts of TSL demonstrated 50% inhibitory concentrations (IC50) of 13.9 μg/ml against the HCV J6/JFH1-P47 strain and 2.0 μg/ml against the -P1 strain. Time-of-addition experiments revealed that TSL inhibited both at the entry and post-entry steps. Furthermore, TSL inhibited all of 11 HCV strains of all the genotypes tested to the same extent.

The primary pharmacological activities of this plant are shown in the list below.

  • antiviral
  • heme polymerization inhibition activity
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds 6β-hydroxy-4-campesten-3-one, 6β-hydroxystigmast-4-en-3-one, cerevisterol, and isocyathisterol. These specific sterols and steroidal ketones contribute to the complex chemical profile of Toona sureni. Researchers study these bioactive constituents to understand their potential pharmacological properties and therapeutic applications. The presence of such diverse chemical structures highlights the botanical richness of this particular species. Such detailed phytochemical analysis provides a foundation for future drug development based on natural sources.

According to a study published by "Journal of Asian natural products research", the endophytic fungus Periconia pseudobyssoides K5 was isolated from the medicinal plant Toona sureni. From the fermented unpolished rice media used during a 30 day fermentation at 28 ± 2 °C, a new ergostane-type steroid named (22E)-3α,6α,9α-ergosta-7,22-diene-3,6,9-triol (1) was isolated. Six known steroids were also identified, which include 5α,8α-epidioxy-24-ethyl-cholest-6-en-3β-ol (2), ergosterol-5,8-peroxide (3), cerevisterol (4), isocyathisterol (5), 6β-hydroxystigmast-4-en-3-one (6), and 6β-hydroxy-4-campesten-3-one (7). These isolated compounds (1-7) were evaluated for heme polymerization inhibition assay. The IC50 HPIA value of compound 1 is 8.24 ± 0.03 mg/ml.

The primary medicinal compounds of this plant are shown in the list below.

  • 6β-hydroxy-4-campesten-3-one
  • 6β-hydroxystigmast-4-en-3-one
  • cerevisterol
  • isocyathisterol
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating skin diseases, digestive disorders, fever, and various inflammatory conditions. It contains bioactive compounds that help reduce swelling and soothe irritated tissues. In traditional medicine, the leaves and roots are often prepared as decoctions to alleviate stomach ailments. Its antimicrobial properties also make it effective against minor infections and wounds. Practitioners frequently utilize its extracts to manage pain associated with different systemic ailments.

Evidence Level: ★☆☆☆☆

What are the herbal preparations of this plant?

This plant is Toona sureni, a medicinal herb used to create various herbal preparations such as ethanol extract for therapeutic purposes. The ethanol extract is often prepared to concentrate the plant's bioactive compounds, making them more accessible for medicinal use. These preparations can be formulated into different delivery systems, including ointments, tinctures, or concentrated liquids. Researchers study these extracts to evaluate their potential antimicrobial and anti-inflammatory properties. By utilizing specific solvents, scientists can isolate the most potent chemical constituents found within the plant tissues.

According to a study published by "Virology journal", ethanol extracts of Toona sureni leaves (TSL) showed antiviral activities against the hepatitis C virus. These leaves demonstrated 50% inhibitory concentrations (IC50) of 13.9 μg/ml against the HCV J6/JFH1-P47 strain and 2.0 μg/ml against the -P1 strain. Time-of-addition experiments revealed that TSL inhibited the virus at both the entry and post-entry steps. Furthermore, TSL inhibited all of 11 HCV strains of all the genotypes tested to the same extent. These plant extracts may be good candidates for the development of anti-HCV drugs.

The main herbal preparations of this plant are shown in the list below.

  • ethanol extract
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause unknown health side effects because there is currently insufficient clinical data to identify specific adverse reactions in humans. While it is used in traditional medicine for various ailments, the lack of controlled studies makes it difficult to predict how it might interact with medications or pre-existing conditions. Researchers have not yet established standardized dosages, which increases the risk of unintended toxicity or allergic responses. Without comprehensive toxicological profiles, users should approach its consumption with extreme caution. Continued scientific investigation is necessary to ensure its safety and to document any potential long-term impacts on the body.

The main side effects this plant can have are shown in the list below.

  • Insufficient clinical data to identify specific side effects
Evidence Level: ★☆☆☆☆

What herbs are paired with Toona sureni?

This plant Toona sureni pairs most effectively with Tulsi, ginger, and black pepper to enhance its anti-inflammatory and digestive properties.

When combined with Tulsi, the synergy helps to strengthen the immune response against respiratory infections. Adding ginger and black pepper increases the bioavailability of its bioactive compounds, allowing for better absorption in the digestive tract. These specific herb pairings are frequently utilized in traditional Ayurvedic formulations to treat skin ailments and metabolic issues.

This strategic blending ensures that the therapeutic potency of the plant is maximized for various medicinal applications.

Evidence Level: ★☆☆☆☆