Tinospora crispa
Tinospora crispa · Accepted scientific name
Scientific literature: Sparse (86 studies) · ★★☆☆☆
Tinospora crispa, scientifically known as Tinospora crispa, is a versatile medicinal shrub widely utilized in traditional Ayurvedic medicine. Renowned for its potent bioactive compounds, it possesses significant antimicrobial, anti-inflammatory, and antioxidant properties. This plant is frequently employed to treat fever, skin disorders, and various digestive ailments effectively.
- Family
- Menispermaceae
- Native range
- Asia-Temperate
- Parts used
- Stem · Leaf
- Common names
- Not available
- Scientific synonyms
- Cocculus Verrucosus · Tinospora Gibbericaulis · 15 more
Names
Scientific Names
Accepted name
Tinospora crispaSynonyms
- Cocculus verrucosus
- Tinospora gibbericaulis
- Cocculus rimosus
- Tinospora thorelii
- Tinospora rumphii
- Tinospora tuberculata
- Tinospora verrucosa
- Menispermum rimosum
- Menispermum tuberculatum
- Nephroia bantamensis
- Menispermum bantamense
- Cocculus crispus
- Chasmanthera crispa
- Menispermum crispum
- Menispermum verrucosum
- Tinospora mastersii
- Cocculus bantamensis
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae and order Ranunculales, it is situated in the family Menispermaceae. Specifically, it is identified by the genus Tinospora.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Ranunculales | WCVP |
| Family | Menispermaceae | WCVP |
| Genus | Tinospora | WCVP |
Distribution
This plant exhibits a wide geographical presence across several key regions in Asia. In China, it is primarily distributed throughout the South-Central areas. Its range extends significantly into the Indian Subcontinent, where it can be found in India and Bangladesh. Additionally, the species is native to specific ecological zones such as Assam and the East Himalaya. Together, these locations highlight its diverse habitat within the subtropical landscape.
| Region | Area | Source |
|---|---|---|
| China | China South-Central | WCVP |
| Indian Subcontinent | Assam | WCVP |
| Indian Subcontinent | Bangladesh | WCVP |
| Indian Subcontinent | East Himalaya | WCVP |
| Indian Subcontinent | India | WCVP |
| Indian Subcontinent | Nepal | WCVP |
| Indian Subcontinent | Sri Lanka | WCVP |
| Indo-China | Cambodia | WCVP |
| Indo-China | Laos | WCVP |
| Indo-China | Myanmar | WCVP |
Plant Parts
This plant, commonly known as Giloy, is a climbing shrub characterized by its vigorous growth habit where it utilizes woody vines to ascend surrounding vegetation. The structure of the plant is defined by its succulent yet sturdy stems, which serve as the primary conduit for nutrients and are often the most valued part for therapeutic use. The lush, green leaves are typically heart-shaped, providing a dense canopy for the climbing organism. In traditional medicine, practitioners often harvest and utilize the dried stems to prepare decoctions and powders, ensuring that the medicinal potency of the stem is preserved through careful processing.| Plant Part | Sources | Consensus |
|---|---|---|
| stem | Nihon yakurigaku zasshi. Folia pharmacologica Japonica (and other 5 sources) | ★★★☆☆ |
| leaf | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Tinospora crispa has 20 reported phytochemicals identified across 6 scientific publications and several other databases. The most consistently reported chemicals include Palmatine, Terpenoids, borapetoside A, borapetoside C, Borapetoside E.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Palmatine | 2 supporting sources | ★☆☆☆☆ |
| Terpenoids | 2 supporting sources | ★☆☆☆☆ |
| borapetoside A | 2 supporting sources | ★☆☆☆☆ |
| borapetoside C | 2 supporting sources | ★☆☆☆☆ |
| Borapetoside E | 1 supporting sources | ★☆☆☆☆ |
| CHLOROGENIC ACID | 1 supporting sources | ★☆☆☆☆ |
| Columbamine | 1 supporting sources | ★☆☆☆☆ |
| Flavonoids | 1 supporting sources | ★☆☆☆☆ |
| Glycosides | 1 supporting sources | ★☆☆☆☆ |
| IL-2 | 1 supporting sources | ★☆☆☆☆ |
Palmatine
- Current issues in molecular biology
- Journal of AOAC International
Terpenoids
- Phytochemistry reviews : proceedings of the Phytochemical Society of Europe
- Current issues in molecular biology
borapetoside A
- Journal of natural products
- Phytomedicine : international journal of phytotherapy and phytopharmacology
borapetoside C
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Current issues in molecular biology
Borapetoside E
- Journal of natural products
CHLOROGENIC ACID
- Current issues in molecular biology
Columbamine
- Journal of AOAC International
Flavonoids
- Phytochemistry reviews : proceedings of the Phytochemical Society of Europe
Glycosides
- Phytotherapy research : PTR
IL-2
- Heliyon
Activities
Tinospora crispa has 9 reported activities identified across 6 scientific publications and several other databases. The most consistently reported activities include Antidiabetic, Anticancer, Antioxidant, Analgesic, Antimicrobial.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antidiabetic | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 3 sources) | ★★☆☆☆ |
| Anticancer | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 2 sources) | ★☆☆☆☆ |
| Antioxidant | RSC advances (and other 2 sources) | ★☆☆☆☆ |
| Analgesic | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 1 sources) | ★☆☆☆☆ |
| Antimicrobial | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 1 sources) | ★☆☆☆☆ |
| Antiparasitic | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 1 sources) | ★☆☆☆☆ |
| Antipyretic | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 1 sources) | ★☆☆☆☆ |
| Cytotoxic | Current issues in molecular biology (and other 1 sources) | ★☆☆☆☆ |
| Hepatoprotective | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Tinospora crispa has 32 reported medicinal uses identified across 6 scientific publications and several other databases. The most consistently reported uses include hypertension, inflammation, insulin resistance, jaundice, type 2 diabetes mellitus.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| hypertension | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 2 sources) | ★☆☆☆☆ |
| inflammation | Nihon yakurigaku zasshi. Folia pharmacologica Japonica (and other 2 sources) | ★☆☆☆☆ |
| insulin resistance | Journal of natural products (and other 2 sources) | ★☆☆☆☆ |
| jaundice | Phytochemistry reviews : proceedings of the Phytochemical Society of Europe (and other 2 sources) | ★☆☆☆☆ |
| type 2 diabetes mellitus | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 2 sources) | ★☆☆☆☆ |
| Diabetes Mellitus | Phytotherapy research : PTR (and other 1 sources) | ★☆☆☆☆ |
| Diabetes mellitus | Journal of pharmacy & bioallied sciences (and other 1 sources) | ★☆☆☆☆ |
| Hyperglycemia | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| Hyperlipidemia | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| antidiabetic | RSC advances (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| aqueous extract | Biological & pharmaceutical bulletin (and other 2 sources) | ★☆☆☆☆ |
| ethanol extract | RSC advances (and other 2 sources) | ★☆☆☆☆ |
| water extract | RSC advances (and other 2 sources) | ★☆☆☆☆ |
| 50% methanol extract | Nihon yakurigaku zasshi. Folia pharmacologica Japonica (and other 1 sources) | ★☆☆☆☆ |
| Tinospora crispa extract | Diabetologia (and other 1 sources) | ★☆☆☆☆ |
| chloroform extract | Acta poloniae pharmaceutica (and other 1 sources) | ★☆☆☆☆ |
| crude ethanol extracts | Molecular medicine reports (and other 1 sources) | ★☆☆☆☆ |
| dried stems (ST) | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| ethyl acetate extract | RSC advances (and other 1 sources) | ★☆☆☆☆ |
| ethyl ether- or water-soluble ones | Nihon yakurigaku zasshi. Folia pharmacologica Japonica (and other 1 sources) | ★☆☆☆☆ |