guduchi
Tinospora cordifolia · Accepted scientific name
Scientific literature: Very Extensive (584 studies) · ★★★★★
Guduchi, scientifically known as Tinospora cordifolia, is a revered medicinal climber in Ayurveda. Often called "Amrita" or the elixir of life, this potent herb possesses profound immunomodulatory, anti-inflammatory, and antioxidant properties. It is widely used to manage fever, enhance immunity, and support overall metabolic health and vitality.
- Family
- Menispermaceae
- Native range
- Asia-Tropical
- Parts used
- Stem · Stems
- Common names
- Not available
- Scientific synonyms
- Menispermum Cordifolium · Tinospora Fosbergii · 3 more
Names
Scientific Names
Accepted name
Tinospora cordifoliaSynonyms
- Menispermum cordifolium
- Tinospora fosbergii
- Cocculus convolvulaceus
- Tinospora mahajanii
- Tinospora cordifolia var. congesta
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Ranunculales, it is classified under the family Menispermaceae. Finally, its specific taxonomic designation is placed within the genus Tinospora.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Ranunculales | WCVP |
| Family | Menispermaceae | WCVP |
| Genus | Tinospora | WCVP |
Distribution
This plant is widely distributed across various regions within the Indian Subcontinent. It can be found growing naturally in the diverse landscapes of India and the neighboring country of Bangladesh. Furthermore, its presence extends to the lush areas of Assam and the mountainous terrain of the East Himalaya. The species also reaches the island nation of the Maldives, showcasing its adaptability to different environments. Together, these locations highlight the significant geographical range of Tinospora cordifolia throughout the region.
| Region | Area | Source |
|---|---|---|
| Indian Subcontinent | Assam | WCVP |
| Indian Subcontinent | Bangladesh | WCVP |
| Indian Subcontinent | East Himalaya | WCVP |
| Indian Subcontinent | India | WCVP |
| Indian Subcontinent | Maldives | WCVP |
| Indian Subcontinent | Sri Lanka | WCVP |
| Indo-China | Andaman Is. | WCVP |
| Indo-China | Myanmar | WCVP |
| Indo-China | Nicobar Is. | WCVP |
| Indo-China | Vietnam | WCVP |
Plant Parts
This plant, commonly known as Giloy, possesses various parts that are utilized for their therapeutic properties. The woody stems are the most frequently used component in Ayurvedic formulations, often prepared as a decoction to boost immunity. The green, heart-shaped leaves are also significant, and even a single dried leaf can be used in specific medicinal preparations. While the lush foliage of the leaves provides a visual characteristic of the climber, the root of the plant is also recognized for its potent healing capabilities. Additionally, the strength of the climbing stem allows the plant to thrive in diverse environments.| Plant Part | Sources | Confidence |
|---|---|---|
| stem | Pakistan journal of biological sciences : PJBS (and other 18 sources) | ★★★★★ |
| stems | BMC plant biology (and other 8 sources) | ★★★★☆ |
| leaves | Malaria journal (and other 6 sources) | ★★★☆☆ |
| root | Pakistan journal of biological sciences : PJBS (and other 4 sources) | ★★☆☆☆ |
| Stem | Molecules (Basel, Switzerland) (and other 3 sources) | ★★☆☆☆ |
| leaf | Microbial ecology (and other 3 sources) | ★★☆☆☆ |
| roots | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| whole plant | Heliyon (and other 2 sources) | ★☆☆☆☆ |
| Tinospora cordifolia extracts | The Gulf journal of oncology (and other 1 sources) | ★☆☆☆☆ |
| dried stems | Phytochemistry (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Tinospora cordifolia has 101 reported phytochemicals identified across 56 scientific publications and several other databases. The most consistently reported chemicals include Steroids, Flavonoids, Terpenoids, berberine, Glycosides.
Most Reported Compounds
| Compound | Sources | Confidence |
|---|---|---|
| Steroids | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 8 sources) | ★★★★☆ |
| Flavonoids | Evidence-based complementary and alternative medicine : eCAM (and other 7 sources) | ★★★★☆ |
| Terpenoids | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 7 sources) | ★★★★☆ |
| berberine | Journal of biomolecular structure & dynamics (and other 7 sources) | ★★★★☆ |
| Glycosides | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 6 sources) | ★★★☆☆ |
| Polysaccharide | PloS one (and other 6 sources) | ★★★☆☆ |
| Tinocordiside | Chemistry & biodiversity (and other 6 sources) | ★★★☆☆ |
| Cordifolioside A | Chemistry & biodiversity (and other 5 sources) | ★★★☆☆ |
| Magnoflorine | BMC plant biology (and other 5 sources) | ★★★☆☆ |
| Flavonoid | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 4 sources) | ★★☆☆☆ |
Activities
Tinospora cordifolia has 36 reported activities identified across 56 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antimicrobial, Hepatoprotective, Antidiabetic.
Most Reported Activities
| Activity | Sources | Confidence |
|---|---|---|
| Antioxidant | Talanta (and other 23 sources) | ★★★★★ |
| Anticancer | Pakistan journal of biological sciences : PJBS (and other 8 sources) | ★★★★☆ |
| Antimicrobial | Journal of ethnopharmacology (and other 8 sources) | ★★★★☆ |
| Hepatoprotective | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (and other 7 sources) | ★★★★☆ |
| Antidiabetic | Journal of ethnopharmacology (and other 6 sources) | ★★★☆☆ |
| Antibacterial | Pakistan journal of biological sciences : PJBS (and other 5 sources) | ★★★☆☆ |
| Antiviral | Current pharmaceutical biotechnology (and other 5 sources) | ★★★☆☆ |
| Antipyretic | Current pharmaceutical biotechnology (and other 4 sources) | ★★☆☆☆ |
| Antispasmodic | Journal of ethnopharmacology (and other 3 sources) | ★★☆☆☆ |
| Cytotoxic | In silico pharmacology (and other 3 sources) | ★★☆☆☆ |
Medicinal Uses
Tinospora cordifolia has 139 reported medicinal uses identified across 56 scientific publications and several other databases. The most consistently reported uses include jaundice, COVID-19, cancer, diabetes mellitus, inflammation.
Most Reported Uses
| Use | Sources | Confidence |
|---|---|---|
| jaundice | Heliyon (and other 9 sources) | ★★★★☆ |
| COVID-19 | Journal of biomolecular structure & dynamics (and other 8 sources) | ★★★★☆ |
| cancer | Heliyon (and other 7 sources) | ★★★★☆ |
| diabetes mellitus | Asian Pacific journal of tropical medicine (and other 6 sources) | ★★★☆☆ |
| inflammation | Advances in clinical and experimental medicine : official organ Wroclaw Medical University (and other 6 sources) | ★★★☆☆ |
| oxidative stress | Journal of natural medicines (and other 6 sources) | ★★★☆☆ |
| rheumatism | Journal of biomolecular structure & dynamics (and other 4 sources) | ★★☆☆☆ |
| Alzheimer's disease | Current neuropharmacology (and other 3 sources) | ★★☆☆☆ |
| Klebsiella pneumoniae | African journal of traditional, complementary, and alternative medicines : AJTCAM (and other 3 sources) | ★★☆☆☆ |
| Staphylococcus aureus | Cellular and molecular biology (Noisy-le-Grand, France) (and other 3 sources) | ★★☆☆☆ |
Preparations
| Preparations | Sources | Confidence |
|---|---|---|
| aqueous extract | Planta medica (and other 4 sources) | ★★☆☆☆ |
| extracts | Indian journal of experimental biology (and other 4 sources) | ★★☆☆☆ |
| alcoholic extract | Planta medica (and other 3 sources) | ★★☆☆☆ |
| chloroform extract | Planta medica (and other 3 sources) | ★★☆☆☆ |
| extract | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer (and other 3 sources) | ★★☆☆☆ |
| methanolic extract | Endocrine regulations (and other 3 sources) | ★★☆☆☆ |
| stem | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (and other 3 sources) | ★★☆☆☆ |
| G1-4A | International immunopharmacology (and other 2 sources) | ★☆☆☆☆ |
| TCE | Evidence-based complementary and alternative medicine : eCAM (and other 2 sources) | ★☆☆☆☆ |
| ethanol extract | Medeniyet medical journal (and other 2 sources) | ★☆☆☆☆ |