guduchi

Tinospora cordifolia · Accepted scientific name

Scientific literature: Very Extensive (584 studies) · ★★★★★

Guduchi, scientifically known as Tinospora cordifolia, is a revered medicinal climber in Ayurveda. Often called "Amrita" or the elixir of life, this potent herb possesses profound immunomodulatory, anti-inflammatory, and antioxidant properties. It is widely used to manage fever, enhance immunity, and support overall metabolic health and vitality.

Family
Menispermaceae
Native range
Asia-Tropical
Parts used
Stem · Leaf
Common names
Not available
Scientific synonyms
Menispermum Cordifolium · Tinospora Fosbergii · 3 more

Names

Scientific Names

Accepted name

Tinospora cordifolia

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Ranunculales, it is classified under the family Menispermaceae. Finally, its specific taxonomic designation is placed within the genus Tinospora.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Ranunculales WCVP
Family Menispermaceae WCVP
Genus Tinospora WCVP

Distribution

This plant is widely distributed across various regions within the Indian Subcontinent. It can be found growing naturally in the diverse landscapes of India and the neighboring country of Bangladesh. Furthermore, its presence extends to the lush areas of Assam and the mountainous terrain of the East Himalaya. The species also reaches the island nation of the Maldives, showcasing its adaptability to different environments. Together, these locations highlight the significant geographical range of Tinospora cordifolia throughout the region.

Region Area Source
Indian Subcontinent Assam WCVP
Indian Subcontinent Bangladesh WCVP
Indian Subcontinent East Himalaya WCVP
Indian Subcontinent India WCVP
Indian Subcontinent Maldives WCVP
Indian Subcontinent Sri Lanka WCVP
Indo-China Andaman Is. WCVP
Indo-China Myanmar WCVP
Indo-China Nicobar Is. WCVP
Indo-China Vietnam WCVP

Plant Parts

This plant, commonly known as Giloy, possesses various parts that are utilized for their therapeutic properties. The woody stems are the most frequently used component in Ayurvedic formulations, often prepared as a decoction to boost immunity. The green, heart-shaped leaves are also significant, and even a single dried leaf can be used in specific medicinal preparations. While the lush foliage of the leaves provides a visual characteristic of the climber, the root of the plant is also recognized for its potent healing capabilities. Additionally, the strength of the climbing stem allows the plant to thrive in diverse environments.
Plant Part Sources Consensus
stem Pakistan journal of biological sciences : PJBS (and other 27 sources) ★★★★★
leaf Pakistan journal of biological sciences : PJBS (and other 11 sources) ★★★★★
root Pakistan journal of biological sciences : PJBS (and other 6 sources) ★★★☆☆

Chemicals

Tinospora cordifolia has 101 reported phytochemicals identified across 44 scientific publications and several other databases. The most consistently reported chemicals include Steroids, Flavonoids, Terpenoids, berberine, Glycosides.

Chemicals reported in Tinospora cordifolia
Chemical Supporting sources Consensus
Steroids 8 supporting sources ★★★★☆
Flavonoids 7 supporting sources ★★★★☆
Terpenoids 7 supporting sources ★★★★☆
berberine 7 supporting sources ★★★★☆
Glycosides 6 supporting sources ★★★☆☆
Polysaccharide 6 supporting sources ★★★☆☆
Tinocordiside 6 supporting sources ★★★☆☆
Cordifolioside A 5 supporting sources ★★★☆☆
Magnoflorine 5 supporting sources ★★★☆☆
Flavonoid 4 supporting sources ★★☆☆☆

Steroids

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Molecules (Basel, Switzerland)
  3. Current pharmaceutical biotechnology
  4. Natural product communications
  5. Functional & integrative genomics
View 3 additional sources
  1. Current pharmaceutical design
  2. Heliyon
  3. Recent patents on endocrine, metabolic & immune drug discovery

Flavonoids

  1. Evidence-based complementary and alternative medicine : eCAM
  2. Functional & integrative genomics
  3. Journal of ethnopharmacology
  4. Medeniyet medical journal
  5. Cellular and molecular biology (Noisy-le-Grand, France)
View 2 additional sources
  1. Journal of traditional and complementary medicine
  2. Recent patents on endocrine, metabolic & immune drug discovery

Terpenoids

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Functional & integrative genomics
  3. TheScientificWorldJournal
  4. Journal of ethnopharmacology
  5. Scientific reports
View 2 additional sources
  1. Medeniyet medical journal
  2. Heliyon

berberine

  1. Journal of biomolecular structure & dynamics
  2. Current topics in medicinal chemistry
  3. 3 Biotech
  4. BioMed research international
  5. Food science and biotechnology
View 2 additional sources
  1. International journal of food sciences and nutrition
  2. International journal of immunopathology and pharmacology

Glycosides

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Molecules (Basel, Switzerland)
  3. Current pharmaceutical biotechnology
  4. Functional & integrative genomics
  5. Current pharmaceutical design
View 1 additional sources
  1. Recent patents on endocrine, metabolic & immune drug discovery

Polysaccharide

  1. PloS one
  2. Immunology letters
  3. International immunopharmacology
  4. Tropical animal health and production
  5. Redox report : communications in free radical research
View 1 additional sources
  1. Indian journal of biochemistry & biophysics

Tinocordiside

  1. Chemistry & biodiversity
  2. Current topics in medicinal chemistry
  3. Combinatorial chemistry & high throughput screening
  4. In silico pharmacology
  5. Journal of biomolecular structure & dynamics
View 1 additional sources
  1. Natural product communications

Cordifolioside A

  1. Chemistry & biodiversity
  2. BMC plant biology
  3. Molecules (Basel, Switzerland)
  4. Current topics in medicinal chemistry
  5. Natural product communications

Magnoflorine

  1. BMC plant biology
  2. Current topics in medicinal chemistry
  3. Natural product communications
  4. Scientific reports
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology

Flavonoid

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Veterinary medicine international
  3. Scientific reports
  4. Journal of complementary & integrative medicine

Activities

Tinospora cordifolia has 36 reported activities identified across 44 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antimicrobial, Hepatoprotective, Antidiabetic.

Most Reported Activities

Activity Sources Consensus
Antioxidant Talanta (and other 23 sources) ★★★★★
Anticancer Pakistan journal of biological sciences : PJBS (and other 8 sources) ★★★★☆
Antimicrobial Journal of ethnopharmacology (and other 8 sources) ★★★★☆
Hepatoprotective Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (and other 7 sources) ★★★★☆
Antidiabetic Journal of ethnopharmacology (and other 6 sources) ★★★☆☆
Antibacterial Pakistan journal of biological sciences : PJBS (and other 5 sources) ★★★☆☆
Antiviral Current pharmaceutical biotechnology (and other 5 sources) ★★★☆☆
Antipyretic Current pharmaceutical biotechnology (and other 4 sources) ★★☆☆☆
Antispasmodic Journal of ethnopharmacology (and other 3 sources) ★★☆☆☆
Cytotoxic In silico pharmacology (and other 3 sources) ★★☆☆☆

Medicinal Uses

Tinospora cordifolia has 139 reported medicinal uses identified across 44 scientific publications and several other databases. The most consistently reported uses include jaundice, COVID-19, cancer, diabetes mellitus, inflammation.

Most Reported Uses

Use Sources Consensus
jaundice Heliyon (and other 9 sources) ★★★★☆
COVID-19 Journal of biomolecular structure & dynamics (and other 8 sources) ★★★★☆
cancer Heliyon (and other 7 sources) ★★★★☆
diabetes mellitus Asian Pacific journal of tropical medicine (and other 6 sources) ★★★☆☆
inflammation Advances in clinical and experimental medicine : official organ Wroclaw Medical University (and other 6 sources) ★★★☆☆
oxidative stress Journal of natural medicines (and other 6 sources) ★★★☆☆
rheumatism Journal of biomolecular structure & dynamics (and other 4 sources) ★★☆☆☆
Alzheimer's disease Current neuropharmacology (and other 3 sources) ★★☆☆☆
Klebsiella pneumoniae African journal of traditional, complementary, and alternative medicines : AJTCAM (and other 3 sources) ★★☆☆☆
Staphylococcus aureus Cellular and molecular biology (Noisy-le-Grand, France) (and other 3 sources) ★★☆☆☆

Preparations

Preparations Sources Consensus
aqueous extract Planta medica (and other 4 sources) ★★☆☆☆
extracts Indian journal of experimental biology (and other 4 sources) ★★☆☆☆
alcoholic extract Planta medica (and other 3 sources) ★★☆☆☆
chloroform extract Planta medica (and other 3 sources) ★★☆☆☆
extract Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer (and other 3 sources) ★★☆☆☆
methanolic extract Endocrine regulations (and other 3 sources) ★★☆☆☆
stem Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (and other 3 sources) ★★☆☆☆
G1-4A International immunopharmacology (and other 2 sources) ★☆☆☆☆
TCE Evidence-based complementary and alternative medicine : eCAM (and other 2 sources) ★☆☆☆☆
ethanol extract Medeniyet medical journal (and other 2 sources) ★☆☆☆☆