Tilia amurensis
What's the taxonomical classification of Tilia amurensis?
Tilia amurensis belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Moving through the hierarchical ranks, the plant is placed in the order Malvales and the family Malvaceae. Finally, its specific taxonomic identity is defined by its membership in the genus Tilia, with the specific epithet amurensis denoting its unique species classification.
| Taxonomic Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malvales |
| Family | Malvaceae |
| Genus | Tilia |
| Species | amurensis |
What are the morphological characteristics of this plant?
Tilia amurensis has simple, ovate to elliptical leaves with serrated margins, cordate bases, and acute tips that typically measure between 5 and 12 centimeters in length. The foliage is characterized by a smooth, lustrous upper surface and a paler underside, often displaying a distinct vein pattern. Its flowers are small, yellowish-white, and fragrant, emerging from axillary clusters during the summer months. Each blossom is uniquely subtended by a specialized, leafy bract that serves to assist in wind-driven seed dispersal. The tree also produces small, nut-like drupes that develop from the fertilized ovaries following pollination.
What is the geographical distribution of this plant?
This plant is native to the Amur, Ussuri, and Primorsky regions of the Russian Far East, as well as parts of northeastern China and the Korean Peninsula. It primarily thrives in the temperate monsoon forests of these East Asian territories. Within these regions, it is often found growing in moist, well-drained soils along river valleys and mountain slopes. The species occupies a specific ecological niche characterized by high humidity and seasonal temperature fluctuations. Its range is largely concentrated in the Manchurian floristic region.
How is this plant cultivated?
This plant requires well-drained, fertile soil and full sun to maximum its growth potential in temperate climates.
It thrives best when provided with regular moisture, though it can tolerate periods of moderate drought once established. Pruning should be performed during the dormant season to maintain a healthy shape and encourage vigorous new growth. Because it is a deciduous species, it benefits from a layer of organic mulch to regulate soil temperature and retain nutrients.
Careful monitoring for pests and fungal diseases is essential for maintaining the long-term health of the tree.
What parts of this plant are used medicinally?
This plant Tilia amurensis is primarily utilized medicinally through its fragrant flowers and leaves, though certain preparations may involve the bark from the trunk. The dried blossoms are frequently brewed into a calming tea to alleviate symptoms of anxiety, insomnia, and common colds. These floral extracts also contain flavonoids and essential oils that provide mild anti-inflammatory and antipyretic properties. While the leaves are sometimes used in topical applications, the inner bark can be processed for specific traditional remedies. This multifaceted use of different plant components makes the species a significant element in herbal pharmacology.
According to a study published by "Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association", the methanolic extract from the trunk of Tilia amurensis Rupr. (Tiliaceae) was found to have significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines. Bioassay-guided fractionation of this extract resulted in the isolation and identification of 10 lignan derivatives, which included 2 new lignan glycosides named tiliamurosides A (1) and B (2). Tiliamuroside B (2) and schizandriside (3) demonstrated significant cytotoxicity against the A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with IC50 values of 3.26-8.89 μM. Additionally, (-)-syringaresinol (8) and (-)-pinoresinol 4-O-β-D-glucopyranoside (10) significantly inhibited nitric oxide production in murine microglia BV-2 with IC50 values of 15.05 and 34.35 μM, respectively.
The parts of this plant that are ued medicinally are shown in the list below.
- trunk
What traditional systems uses this plant?
This plant, known as Amur lime, has been utilized in Traditional Korean Medicine to address various ailments through its flowers and bark. Practitioners historically employed the species to treat respiratory issues and promote relaxation in patients. The botanical components were often prepared as decoctions or teas to alleviate inflammation and soothe the nervous system. Beyond its medicinal applications, the plant held a place in regional folklore and herbal traditions across East Asia. Its historical use reflects a long-standing reliance on local flora for managing common physical discomforts.
According to a study published by "Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association", the methanolic extract from the trunk of Tilia amurensis Rupr. was found to have significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines. A bioassay-guided fractionation and chemical investigation of this extract resulted in the isolation and identification of 10 lignan derivatives, including two new lignan glycosides named tiliamurosides A (1) and B (2). Tiliamuroside B (2) and schizandriside (3) showed significant cytotoxicity against the A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with inhibitory concentration (IC50) values of 3.26-8.89 μM. Additionally, (-)-syringaresinol (8) and (-)-pinoresinol 4-O-β-D-glucopyranoside (10) significantly inhibited nitric oxide (NO) production in murine microglia BV-2 with IC50 values of 15.05 and 34.35 μM, respectively.
The hystorical systems that uses this plant are shown in the list below.
- Traditional Korean Medicine
What are the pharmacological activities of Tilia amurensis?
This plant has antioxidant and anti-inflammatory pharmacological activities. These specific biological effects are documented through various studies focusing on its chemical constituents. Researchers have investigated how its bioactive compounds interact with cellular pathways to reduce oxidative stress. While the current data confirms these two properties, further exploration is required to identify additional therapeutic benefits. Expanding the scope of scientific research could reveal a more comprehensive profile of its medicinal potential.
As discussed in a study, the methanolic extract from the trunk of Tilia amurensis Rupr. demonstrated significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines. Chemical investigation of this extract led to the isolation and identification of 10 lignan derivatives, including two new lignan glycosides named tiliamurosides A (1) and B (2). Tiliamuroside B (2) and schizandriside (3) exhibited significant cytotoxicity against the A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with inhibitory concentration (IC50) values ranging from 3.26-8.89 μM. Additionally, (-)-syringaresinol (8) and (-)-pinoresinol 4-O-β-D-glucopyranoside (10) from the plant significantly inhibited nitric oxide (NO) production in murine microglia BV-2. These inhibitory activities were recorded with IC50 values of 15.05 μM and 34.35 μM, respectively.
The primary pharmacological activities of this plant are shown in the list below.
- anti-inflammatory
- antitumor
What medicinal compounds this plant contains?
This plant contains the medicinal compounds tiliamurosides A, tiliamurosides B, (-) -pinoresinol 4-O-β-D-glucopyranoside, (-)-syringaresinol, and schizandriside. These specific phytochemicals are distributed throughout various parts of the species and contribute to its unique chemical profile. Research into these substances focuses on their potential biological activities and therapeutic properties. The presence of these lignans and glycosides distinguishes the chemical makeup of Tilia amurensis from other related flora. Such detailed composition provides a basis for further pharmacological investigation.
According to a study published by "Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association", a methanolic extract from the trunk of Tilia amurensis Rupr. was found to contain 10 lignan derivatives. This investigation included the identification of two new lignan glycosides named tiliamurosides A (1) and B (2). Among these, tiliamuroside B (2) and schizandriside (3) demonstrated significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with IC50 values ranging from 3.26 to 8.89 μM. Additionally, (-)-syringaresinol (8) and (-)-pinoresinol 4-O-β-D-glucopyranoside (10) significantly inhibited nitric oxide production in murine microglia BV-2. These two compounds showed IC50 values of 15.05 μM and 34.35 μM, respectively.
The primary medicinal compounds of this plant are shown in the list below.
- tiliamurosides A
- tiliamurosides B
- (-) -pinoresinol 4-O-β-D-glucopyranoside
- (-)-syringaresinol
- schizandriside
What health conditions is this plant used for?
This plant is used for none of the provided items are relevant to the health conditions for which Tilia amurensis is used. Scientific literature does not support the use of this specific species for treating any particular human medical ailments. While other members of the Tilia genus are often studied for their sedative or antipyretic properties, this particular variety lacks documented clinical applications. Consequently, there are no established therapeutic indications for this plant in traditional or modern medicine. Researchers have not identified any specific healing benefits associated with its consumption.
As discussed in a study, the methanolic extract from the trunk of Tilia amurensis Rupr. shows significant cytotoxicity against 4 specific cell lines, including A549, SK-OV-3, SK-MEL-2, and HCT-15. Within this research, 10 lignan derivatives were isolated, featuring 2 new lignan glycosides named tiliamurosides A and B. The compounds tiliamuroside B and schizandriside demonstrated cytotoxicity against the 4 cell lines with IC50 values ranging from 3.26 to 8.89 μM. Additionally, the plant contains components that target inflammation by inhibiting nitric oxide production in murine microglia BV-2 cells. Specifically, (-)-syringaresinol and (-)-pinoresinol 4-O-β-D-glucopyranoside showed inhibitory effects with IC50 values of 15.05 and 34.35 μM, respectively.
The main health conditions this plant is used for are shown in the list below.
- None of the provided items are relevant to the health conditions Tilia amurensis is used for.
What are the herbal preparations of this plant?
This plant is Tilia amurensis, a species used to create medicinal herbal preparations such as methanolic extract for its therapeutic properties. Researchers often utilize methanol to isolate specific bioactive compounds like flavonoids and polyphenols from the plant's tissues. These extracts are frequently studied for their potential antioxidant and anti-inflammatory effects in various biological models. Beyond concentrated extracts, other traditional preparations may include aqueous infusions or decoctions made from the bark or leaves. Such diverse forms allow for different methods of delivering the plant's chemical constituents for medicinal use.
According to a study published by "Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association", a methanolic extract from the trunk of Tilia amurensis Rupr. demonstrates significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines. Chemical investigation of this extract led to the isolation and identification of 10 lignan derivatives, which include 2 new lignan glycosides named tiliamurosides A (1) and B (2). Tiliamuroside B (2) and schizandriside (3) exhibited significant cytotoxicity against the A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with IC50 values ranging from 3.26 to 8.89 μM. Additionally, (-)-syringaresinol (8) and (-)-pinoresinol 4-O-β-D-glucopyranoside (10) inhibited nitric oxide production in murine microglia BV-2 with IC50 values of 15.05 and 34.35 μM, respectively.
The main herbal preparations of this plant are shown in the list below.
- methanolic extract
What side effects this plant can have?
This plant can cause nausea, dizziness, and allergic reactions in individuals who consume it or come into contact with its components. Some users may experience gastrointestinal distress or a feeling of lightheadedness shortly after ingestion. Allergic reactions can manifest as skin rashes, itching, or respiratory discomfort in sensitive people. Because these side effects vary in intensity, caution is necessary when using any part of the species. Monitoring your body's response is essential to avoid more severe adverse reactions.
The main side effects this plant can have are shown in the list below.
- Nausea
- Dizziness
- Allergic reactions
What herbs are paired with Tilia amurensis?
This plant pairs most effectively with peppermint, lemon balm, and chamomile to enhance its naturally sweet and honey-like aromatic profile.
Combining Tilia amurensis with peppermint provides a cooling undertone that balances the warmth of the linden blossoms. Adding lemon balm introduces a citrusy brightness that complements the floral depth of the infusion. For a more soothing effect, mixing these flowers with chamomile creates a gentle sedative tea suitable for relaxation.
These combinations work together to create a harmonious flavor profile that is both soothing and fragrant.