clove

Syzygium aromaticum · Accepted scientific name

Scientific literature: Very Extensive (1435 studies) · ★★★★★

Clove, scientifically known as Syzygium aromaticum, is a highly aromatic spice derived from the dried flower buds of a tropical evergreen tree. Renowned for its intense flavor and potent medicinal properties, it contains eugenol, offering powerful antioxidant, antibacterial, and analgesic benefits essential in traditional and modern medicine.

Family
Myrtaceae
Native range
Africa
Parts used
Flower · Leaf
Common names
Clove · Clove · 1 more
Scientific synonyms
Eugenia Caryophyllus · Myrtus Caryophyllus · 4 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Syzygium aromaticum

Synonyms

Regional and Traditional Names

Spanish:

  • Clavero
  • Clavo de olor
  • Eugenia caryophyllata
  • Clavos de olor
  • Clavo
  • Syzgyum aromaticum
  • clavero giroflé
  • clavo de olor
  • árbol del clavo
  • Clavo
  • clavero

German:

  • Gewürznelke
  • Gewürznelkenbaum
  • Eugenia caryophyllata
  • Gewürznelkenbaum

French:

  • Giroflier
  • Clous de girofle
  • Eugenia cariophyllata
  • Girofle
  • Clou de girofle
  • giroflier

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, scientifically known as Syzygium aromaticum, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Myrtales and the family Myrtaceae. Its specific taxonomic placement is within the genus Syzygium.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Myrtales
Family Myrtaceae
Genus Syzygium

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specialized geographical distribution concentrated primarily within tropical maritime regions. In West-Central Tropical Africa, its presence is noted around the Gulf of Guinea Islands. Moving toward East Tropical Africa, the species can be found in Tanzania. Its range extends significantly across the Western Indian Ocean, encompassing the Comoros. Finally, the distribution includes the prominent islands of Madagascar and the Seychelles.

Region Area
West-Central Tropical Africa Gulf of Guinea Is.
East Tropical Africa Tanzania
Western Indian Ocean Comoros
Western Indian Ocean Madagascar
Western Indian Ocean Seychelles
Indian Subcontinent India
Malesia Borneo
Malesia Maluku
Northwestern Pacific Caroline Is.
Caribbean Trinidad-Tobago

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Syzygium aromaticum is characterized by its existence as a perennial plant, ensuring its long-term presence within its ecological niche. As a phanerophyte, it develops significant woody structures that elevate its photosynthetic organs well above the ground level, a trait further specified by its classification as a nanophanerophyte. Throughout its life cycle, the plant maintains an evergreen deciduousness, consistently retaining its foliage to facilitate continuous metabolic activity.

Deciduousness :
evergreen
Life form :
nanophanerophyte
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Syzygium aromaticum is characterized by its growth form as a woody tree that functions as a self-supporting, independent organism. It is a terrestrial species, not categorized as an aquatic, semiaquatic, or epiphytic plant. As a non-parasitic species, it maintains an independent lifestyle without reliance on a host. In terms of stature, the plant exhibits significant variation in height, with recorded measurements ranging from a minimum of 8 m to a maximum of 12 m, although the mean plant height is observed at approximately 20 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Parasite :
independent
Plant height max:
12 m
Plant height mean:
20 m
Plant height min:
8 m
Woodiness :
woody

Physiology

The physiology of Syzygium aromaticum is characterized by a C3 photosynthetic pathway, which governs its carbon assimilation processes and metabolic efficiency under typical tropical environmental conditions. As a C3 plant, it utilizes the enzyme Rubisco to fix atmospheric carbon dioxide directly into the Calvin cycle, a process that is highly effective in the humid, warm climates where the species thrives. In terms of nutrient cycling and symbiotic relationships, the plant is not a nitrogen fixer, meaning it does not possess the specialized nodules or symbiotic associations with diazotrophic bacteria required to convert atmospheric nitrogen into usable forms; instead, it relies on the uptake of nitrates and ammonium from the soil through its root system.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproduction of Syzygium aromaticum is characterized by a biotic pollination syndrome, primarily driven by interactions with animal vectors rather than abiotic factors. Specifically, the plant relies on insects for pollen transfer, with bees identified as a key component of its pollination mechanism. While the species is capable of self-fertilization, its reproductive success is closely tied to these biotic interactions. The resulting seeds exhibit significant variability in size and weight; they possess a mean seed mass of approximately 0.37358425 g, though individual seed masses can range from a minimum of 0.000474 g to a maximum of 1.49254 g.

Pollination syndrome :
insect
Pollination syndrome :
bee
Pollination syndrome :
biotic
Seed mass max:
1.49254 g
Seed mass mean:
0.37358425 g
Seed mass min:
0.000474 g
Self fertilization :
present

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Syzygium aromaticum has 4 reported plant parts identified across 15 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include flower, leaf, fruit, seed.

Plant parts reported in Syzygium aromaticum
Plant part Supporting sources Consensus
Flower 10 supporting sources ★★★★★
Leaf 3 supporting sources ★★☆☆☆
Fruit 1 supporting sources ★☆☆☆☆
Seed 1 supporting sources ★☆☆☆☆

Flower

  1. Biological & pharmaceutical bulletin
  2. Asian Pacific journal of tropical medicine
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. Veterinary parasitology
  5. Parasitology research
View 5 additional sources
  1. International journal of cosmetic science
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Mediators of inflammation
  4. Parkinson's disease
  5. Journal of ethnobiology and ethnomedicine

Leaf

  1. Asian Pacific journal of tropical medicine
  2. Open life sciences
  3. Biomolecules

Fruit

  1. Biomolecules

Seed

  1. Asian Pacific journal of tropical medicine

Chemicals

Syzygium aromaticum has 261 reported phytochemicals identified across 15 scientific publications and several other databases. The most consistently reported chemicals include eugenol, CLOVE OIL, Caryophyllene, Gallic acid, OLEANOLIC ACID.

Chemicals reported in Syzygium aromaticum
Chemical Supporting sources Consensus
eugenol 47 supporting sources ★★★★★
CLOVE OIL 10 supporting sources ★★★★★
Caryophyllene 5 supporting sources ★★★☆☆
Gallic acid 5 supporting sources ★★★☆☆
OLEANOLIC ACID 5 supporting sources ★★★☆☆
quercetin 5 supporting sources ★★★☆☆
Eugenol acetate 4 supporting sources ★★☆☆☆
Flavonoids 4 supporting sources ★★☆☆☆
Acetyl eugenol 3 supporting sources ★★☆☆☆
Isoeugenol 3 supporting sources ★★☆☆☆

eugenol

  1. Dr. Duke
  2. Advances in experimental medicine and biology
  3. Cell biology international
  4. Journal of clinical and experimental dentistry
  5. Pharmaceutics
View 42 additional sources
  1. The Journal of pharmacy and pharmacology
  2. BMC veterinary research
  3. Frontiers in nutrition
  4. Antibiotics (Basel, Switzerland)
  5. Plants (Basel, Switzerland)
  6. Insects
  7. Cancer biotherapy & radiopharmaceuticals
  8. Naunyn-Schmiedeberg's archives of pharmacology
  9. Journal of natural products
  10. Biomolecules
  11. Antioxidants (Basel, Switzerland)
  12. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  13. Toxicology mechanisms and methods
  14. Journal of AOAC International
  15. Toxicon : official journal of the International Society on Toxinology
  16. Molecules (Basel, Switzerland)
  17. TheScientificWorldJournal
  18. Letters in applied microbiology
  19. Journal of evidence-based complementary & alternative medicine
  20. Journal of arthropod-borne diseases
  21. Frontiers in microbiology
  22. Scientific reports
  23. International journal of microbiology
  24. Food & function
  25. Food chemistry
  26. Medical and veterinary entomology
  27. Critical reviews in microbiology
  28. Chemistry & biodiversity
  29. Asian Pacific journal of tropical biomedicine
  30. Phytomedicine : international journal of phytotherapy and phytopharmacology
  31. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  32. Oxidative medicine and cellular longevity
  33. Parkinson's disease
  34. Journal de mycologie medicale
  35. Fitoterapia
  36. Planta medica
  37. Pharmaceutical development and technology
  38. AMB Express
  39. Pathogens (Basel, Switzerland)
  40. Complementary therapies in medicine
  41. Journal of microbiology and biotechnology
  42. Journal of agricultural and food chemistry

CLOVE OIL

  1. Molecules (Basel, Switzerland)
  2. BMC plant biology
  3. Pakistan journal of pharmaceutical sciences
  4. Asian Pacific journal of allergy and immunology
  5. Journal of clinical and diagnostic research : JCDR
View 5 additional sources
  1. Evidence-based complementary and alternative medicine : eCAM
  2. Animals : an open access journal from MDPI
  3. Cellular and molecular biology (Noisy-le-Grand, France)
  4. Recent patents on drug delivery & formulation
  5. The Southeast Asian journal of tropical medicine and public health

Caryophyllene

  1. Dr. Duke
  2. BMC veterinary research
  3. Toxicology mechanisms and methods
  4. Food & function
  5. AMB Express

Gallic acid

  1. Dr. Duke
  2. Luminescence : the journal of biological and chemical luminescence
  3. Asian Pacific journal of tropical biomedicine
  4. PloS one
  5. Biomolecules

OLEANOLIC ACID

  1. Dr. Duke
  2. Oncology research
  3. Mediators of inflammation
  4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  5. Chemical & pharmaceutical bulletin

quercetin

  1. Dr. Duke
  2. Frontiers in microbiology
  3. Scientific reports
  4. PloS one
  5. Biomolecules

Eugenol acetate

  1. Dr. Duke
  2. Frontiers in nutrition
  3. Antioxidants (Basel, Switzerland)
  4. Asian Pacific journal of tropical biomedicine

Flavonoids

  1. Journal of pharmaceutical and biomedical analysis
  2. BMC complementary medicine and therapies
  3. Antibiotics (Basel, Switzerland)
  4. AMB Express

Acetyl eugenol

  1. Dr. Duke
  2. Food & function
  3. Parkinson's disease

Isoeugenol

  1. Dr. Duke
  2. Advances in experimental medicine and biology
  3. Frontiers in nutrition

Activities

Syzygium aromaticum has 597 reported activities identified across 15 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Anticancer, Antimicrobial, Antifungal.

Activities reported in Syzygium aromaticum
Activity Supporting sources Consensus
Antioxidant 20 supporting sources ★★★★★
Antibacterial 11 supporting sources ★★★★★
Anticancer 10 supporting sources ★★★★★
Antimicrobial 9 supporting sources ★★★★☆
Antifungal 8 supporting sources ★★★★☆
Analgesic 7 supporting sources ★★★★☆
Antiviral 7 supporting sources ★★★★☆
Antiseptic 5 supporting sources ★★★☆☆
Neuroprotective 4 supporting sources ★★☆☆☆
Antinociceptive 3 supporting sources ★★☆☆☆

Antioxidant

  1. Dr. Duke
  2. Advances in experimental medicine and biology
  3. Scientific reports
  4. Frontiers in nutrition
  5. Plants (Basel, Switzerland)
View 15 additional sources
  1. Cancer biotherapy & radiopharmaceuticals
  2. Biomolecules
  3. Antioxidants (Basel, Switzerland)
  4. Molecules (Basel, Switzerland)
  5. Journal of pharmaceutical and biomedical analysis
  6. Toxicon : official journal of the International Society on Toxinology
  7. Food & function
  8. Dose-response : a publication of International Hormesis Society
  9. Critical reviews in microbiology
  10. Asian Pacific journal of tropical biomedicine
  11. Oxidative medicine and cellular longevity
  12. Parkinson's disease
  13. The Medical journal of Malaysia
  14. Pharmaceutical development and technology
  15. Journal of agricultural and food chemistry

Antibacterial

  1. Dr. Duke
  2. Antibiotics (Basel, Switzerland)
  3. Molecules (Basel, Switzerland)
  4. Scientific reports
  5. Biomolecules
View 6 additional sources
  1. Antioxidants (Basel, Switzerland)
  2. Toxicon : official journal of the International Society on Toxinology
  3. BMC complementary medicine and therapies
  4. Oncology research
  5. The Medical journal of Malaysia
  6. Animals : an open access journal from MDPI

Anticancer

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Cell biology international
  4. Cancer biotherapy & radiopharmaceuticals
  5. Beni-Suef University journal of basic and applied sciences
View 5 additional sources
  1. Biomolecules
  2. Antioxidants (Basel, Switzerland)
  3. Phytotherapy research : PTR
  4. Biomedicines
  5. Open life sciences

Antimicrobial

  1. Bioprocess and biosystems engineering
  2. Molecules (Basel, Switzerland)
  3. Antibiotics (Basel, Switzerland)
  4. Current medicinal chemistry
  5. Journal of clinical and diagnostic research : JCDR
View 4 additional sources
  1. Chemistry & biodiversity
  2. Asian Pacific journal of tropical biomedicine
  3. AMB Express
  4. Pathogens (Basel, Switzerland)

Antifungal

  1. Advances in dental research
  2. Molecules (Basel, Switzerland)
  3. Biomolecules
  4. Applied microbiology and biotechnology
  5. Antioxidants (Basel, Switzerland)
View 3 additional sources
  1. Oncology research
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology
  3. Food science & nutrition

Analgesic

  1. Dr. Duke
  2. Frontiers in nutrition
  3. Biomolecules
  4. Antioxidants (Basel, Switzerland)
  5. Toxicon : official journal of the International Society on Toxinology
View 2 additional sources
  1. Mediators of inflammation
  2. Open life sciences

Antiviral

  1. Dr. Duke
  2. Cancer biotherapy & radiopharmaceuticals
  3. Biomolecules
  4. Molecules (Basel, Switzerland)
  5. Saudi journal of biological sciences
View 2 additional sources
  1. Oncology research
  2. Open life sciences

Antiseptic

  1. Dr. Duke
  2. Biomolecules
  3. Antioxidants (Basel, Switzerland)
  4. Oncology research
  5. Evidence-based complementary and alternative medicine : eCAM

Neuroprotective

  1. Dr. Duke
  2. Frontiers in nutrition
  3. Parkinson's disease
  4. Biomolecules

Antinociceptive

  1. Dr. Duke
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Conditions

Syzygium aromaticum has 124 reported investigations on conditions identified across 15 scientific publications and several other databases. The most consistently reported conditions include Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, cancer, inflammation.

Conditions investigated for Syzygium aromaticum
Condition Supporting sources Consensus
Staphylococcus aureus 7 supporting sources ★★★★☆
Escherichia coli 6 supporting sources ★★★☆☆
Pseudomonas aeruginosa 6 supporting sources ★★★☆☆
Cancer 6 supporting sources ★★★☆☆
Inflammation 5 supporting sources ★★★☆☆
Oxidative stress 5 supporting sources ★★★☆☆
Covid-19 4 supporting sources ★★☆☆☆
Streptococcus mutans 4 supporting sources ★★☆☆☆
Toothache 4 supporting sources ★★☆☆☆
Candida albicans 3 supporting sources ★★☆☆☆

Staphylococcus aureus

  1. Journal of intercultural ethnopharmacology
  2. Pharmaceutical biology
  3. Molecules (Basel, Switzerland)
  4. Plants (Basel, Switzerland)
  5. Frontiers in microbiology
View 2 additional sources
  1. Food science and biotechnology
  2. Life (Basel, Switzerland)

Escherichia coli

  1. Journal of intercultural ethnopharmacology
  2. Scientific reports
  3. Molecules (Basel, Switzerland)
  4. Frontiers in microbiology
  5. Chemistry & biodiversity
View 1 additional sources
  1. Journal of food protection

Pseudomonas aeruginosa

  1. Journal of intercultural ethnopharmacology
  2. Scientific reports
  3. Pharmaceutical biology
  4. Molecules (Basel, Switzerland)
  5. BMC complementary medicine and therapies
View 1 additional sources
  1. Chemistry & biodiversity

Cancer

  1. Advances in experimental medicine and biology
  2. Beni-Suef University journal of basic and applied sciences
  3. Phytotherapy research : PTR
  4. Oxidative medicine and cellular longevity
  5. Planta medica
View 1 additional sources
  1. Molecules (Basel, Switzerland)

Inflammation

  1. Food science & nutrition
  2. Naunyn-Schmiedeberg's archives of pharmacology
  3. Oxidative medicine and cellular longevity
  4. Dose-response : a publication of International Hormesis Society
  5. Inflammopharmacology

Oxidative stress

  1. Toxicon : official journal of the International Society on Toxinology
  2. Food & function
  3. Dose-response : a publication of International Hormesis Society
  4. Oxidative medicine and cellular longevity
  5. Biomolecules

Covid-19

  1. Protein and peptide letters
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Molecules (Basel, Switzerland)
  4. Saudi journal of biological sciences

Streptococcus mutans

  1. Open access Macedonian journal of medical sciences
  2. Journal of ethnopharmacology
  3. 3 Biotech
  4. Nigerian medical journal : journal of the Nigeria Medical Association

Toothache

  1. Frontiers in nutrition
  2. Avicenna journal of phytomedicine
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

Candida albicans

  1. Scientific reports
  2. Molecules (Basel, Switzerland)
  3. Nigerian medical journal : journal of the Nigeria Medical Association

Preparations

Syzygium aromaticum has 55 reported preparations identified across 15 scientific publications and several other databases. The most consistently reported preparations include essential oils, essential oil, aqueous extract, extracts, water extracts.

Preparations reported for Syzygium aromaticum
Preparation Supporting sources Consensus
Essential oils 10 supporting sources ★★★★★
Essential oil 6 supporting sources ★★★☆☆
Aqueous extract 4 supporting sources ★★☆☆☆
Extracts 4 supporting sources ★★☆☆☆
Water extracts 3 supporting sources ★★☆☆☆
Eo 2 supporting sources ★☆☆☆☆
Essential oils 2 supporting sources ★☆☆☆☆
Clove oil 2 supporting sources ★☆☆☆☆
Ethanol extract 2 supporting sources ★☆☆☆☆
Ethanol extracts 2 supporting sources ★☆☆☆☆

Essential oils

  1. Journal of food protection
  2. Applied microbiology and biotechnology
  3. Parasitology research
  4. Tropical biomedicine
  5. Molecules (Basel, Switzerland)
View 5 additional sources
  1. Letters in applied microbiology
  2. BMC complementary and alternative medicine
  3. Journal of medicinal food
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Evidence-based complementary and alternative medicine : eCAM

Essential oil

  1. Pakistan journal of biological sciences : PJBS
  2. Plants (Basel, Switzerland)
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. Medical and veterinary entomology
  5. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
View 1 additional sources
  1. Journal of ethnopharmacology

Aqueous extract

  1. BMC complementary and alternative medicine
  2. Phytotherapy research : PTR
  3. West African journal of pharmacology and drug research
  4. Pharmaceutical biology

Extracts

  1. Brazilian journal of otorhinolaryngology
  2. Journal of ethnopharmacology
  3. Evidence-based complementary and alternative medicine : eCAM
  4. Inflammopharmacology

Water extracts

  1. Phytotherapy research : PTR
  2. Journal of ethnopharmacology
  3. Journal of natural medicines

Eo

  1. Letters in applied microbiology
  2. Antibiotics (Basel, Switzerland)

Essential oils

  1. Journal de mycologie medicale
  2. Natural product research

Clove oil

  1. Biomolecules
  2. Asian Pacific journal of allergy and immunology

Ethanol extract

  1. West African journal of pharmacology and drug research
  2. Experimental and therapeutic medicine

Ethanol extracts

  1. Experimental & applied acarology
  2. Molecules (Basel, Switzerland)