clove
Syzygium aromaticum · Accepted scientific name
Scientific literature: Very Extensive (1435 studies) · ★★★★★
Clove, scientifically known as Syzygium aromaticum, is a highly aromatic spice derived from the dried flower buds of a tropical evergreen tree. Renowned for its intense flavor and potent medicinal properties, it contains eugenol, offering powerful antioxidant, antibacterial, and analgesic benefits essential in traditional and modern medicine.
Names and Synonyms
Common Names
- clove
- clove
- clovetree
Scientific Names
Accepted name
Syzygium aromaticumSynonyms
- Eugenia caryophyllus
- Myrtus caryophyllus
- Eugenia caryophyllata
- Jambosa caryophyllus
- Caryophyllus silvestris
- Caryophyllus aromaticus
Regional and Traditional Names
Spanish:
- Clavero
- Clavo de olor
- Eugenia caryophyllata
- Clavos de olor
- Clavo
- Syzgyum aromaticum
- clavero giroflé
- clavo de olor
- árbol del clavo
- Clavo
- clavero
German:
- Gewürznelke
- Gewürznelkenbaum
- Eugenia caryophyllata
- Gewürznelkenbaum
French:
- Giroflier
- Clous de girofle
- Eugenia cariophyllata
- Girofle
- Clou de girofle
- giroflier
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant, scientifically known as Syzygium aromaticum, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Myrtales and the family Myrtaceae. Its specific taxonomic placement is within the genus Syzygium.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Myrtales |
| Family | Myrtaceae |
| Genus | Syzygium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specialized geographical distribution concentrated primarily within tropical maritime regions. In West-Central Tropical Africa, its presence is noted around the Gulf of Guinea Islands. Moving toward East Tropical Africa, the species can be found in Tanzania. Its range extends significantly across the Western Indian Ocean, encompassing the Comoros. Finally, the distribution includes the prominent islands of Madagascar and the Seychelles.
| Region | Area |
|---|---|
| West-Central Tropical Africa | Gulf of Guinea Is. |
| East Tropical Africa | Tanzania |
| Western Indian Ocean | Comoros |
| Western Indian Ocean | Madagascar |
| Western Indian Ocean | Seychelles |
| Indian Subcontinent | India |
| Malesia | Borneo |
| Malesia | Maluku |
| Northwestern Pacific | Caroline Is. |
| Caribbean | Trinidad-Tobago |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Syzygium aromaticum is characterized by its existence as a perennial plant, ensuring its long-term presence within its ecological niche. As a phanerophyte, it develops significant woody structures that elevate its photosynthetic organs well above the ground level, a trait further specified by its classification as a nanophanerophyte. Throughout its life cycle, the plant maintains an evergreen deciduousness, consistently retaining its foliage to facilitate continuous metabolic activity.
- Deciduousness :
- evergreen
- Life form :
- nanophanerophyte
- Life form :
- phanerophyte
- Lifecycle :
- perennial
Morphology
The morphology of Syzygium aromaticum is characterized by its growth form as a woody tree that functions as a self-supporting, independent organism. It is a terrestrial species, not categorized as an aquatic, semiaquatic, or epiphytic plant. As a non-parasitic species, it maintains an independent lifestyle without reliance on a host. In terms of stature, the plant exhibits significant variation in height, with recorded measurements ranging from a minimum of 8 m to a maximum of 12 m, although the mean plant height is observed at approximately 20 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Parasite :
- independent
- Plant height max:
- 12 m
- Plant height mean:
- 20 m
- Plant height min:
- 8 m
- Woodiness :
- woody
Physiology
The physiology of Syzygium aromaticum is characterized by a C3 photosynthetic pathway, which governs its carbon assimilation processes and metabolic efficiency under typical tropical environmental conditions. As a C3 plant, it utilizes the enzyme Rubisco to fix atmospheric carbon dioxide directly into the Calvin cycle, a process that is highly effective in the humid, warm climates where the species thrives. In terms of nutrient cycling and symbiotic relationships, the plant is not a nitrogen fixer, meaning it does not possess the specialized nodules or symbiotic associations with diazotrophic bacteria required to convert atmospheric nitrogen into usable forms; instead, it relies on the uptake of nitrates and ammonium from the soil through its root system.
- Nitrogen fixer :
- no
- Photosynthetic pathway :
- C3
Reproduction
The reproduction of Syzygium aromaticum is characterized by a biotic pollination syndrome, primarily driven by interactions with animal vectors rather than abiotic factors. Specifically, the plant relies on insects for pollen transfer, with bees identified as a key component of its pollination mechanism. While the species is capable of self-fertilization, its reproductive success is closely tied to these biotic interactions. The resulting seeds exhibit significant variability in size and weight; they possess a mean seed mass of approximately 0.37358425 g, though individual seed masses can range from a minimum of 0.000474 g to a maximum of 1.49254 g.
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
- Seed mass max:
- 1.49254 g
- Seed mass mean:
- 0.37358425 g
- Seed mass min:
- 0.000474 g
- Self fertilization :
- present
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Syzygium aromaticum has 4 reported plant parts identified across 15 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include flower, leaf, fruit, seed.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Flower | 10 supporting sources | ★★★★★ |
| Leaf | 3 supporting sources | ★★☆☆☆ |
| Fruit | 1 supporting sources | ★☆☆☆☆ |
| Seed | 1 supporting sources | ★☆☆☆☆ |
Flower
- Biological & pharmaceutical bulletin
- Asian Pacific journal of tropical medicine
- Naunyn-Schmiedeberg's archives of pharmacology
- Veterinary parasitology
- Parasitology research
View 5 additional sources
- International journal of cosmetic science
- Evidence-based complementary and alternative medicine : eCAM
- Mediators of inflammation
- Parkinson's disease
- Journal of ethnobiology and ethnomedicine
Leaf
- Asian Pacific journal of tropical medicine
- Open life sciences
- Biomolecules
Fruit
- Biomolecules
Seed
- Asian Pacific journal of tropical medicine
Chemicals
Syzygium aromaticum has 261 reported phytochemicals identified across 15 scientific publications and several other databases. The most consistently reported chemicals include eugenol, CLOVE OIL, Caryophyllene, Gallic acid, OLEANOLIC ACID.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| eugenol | 47 supporting sources | ★★★★★ |
| CLOVE OIL | 10 supporting sources | ★★★★★ |
| Caryophyllene | 5 supporting sources | ★★★☆☆ |
| Gallic acid | 5 supporting sources | ★★★☆☆ |
| OLEANOLIC ACID | 5 supporting sources | ★★★☆☆ |
| quercetin | 5 supporting sources | ★★★☆☆ |
| Eugenol acetate | 4 supporting sources | ★★☆☆☆ |
| Flavonoids | 4 supporting sources | ★★☆☆☆ |
| Acetyl eugenol | 3 supporting sources | ★★☆☆☆ |
| Isoeugenol | 3 supporting sources | ★★☆☆☆ |
eugenol
- Dr. Duke
- Advances in experimental medicine and biology
- Cell biology international
- Journal of clinical and experimental dentistry
- Pharmaceutics
View 42 additional sources
- The Journal of pharmacy and pharmacology
- BMC veterinary research
- Frontiers in nutrition
- Antibiotics (Basel, Switzerland)
- Plants (Basel, Switzerland)
- Insects
- Cancer biotherapy & radiopharmaceuticals
- Naunyn-Schmiedeberg's archives of pharmacology
- Journal of natural products
- Biomolecules
- Antioxidants (Basel, Switzerland)
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Toxicology mechanisms and methods
- Journal of AOAC International
- Toxicon : official journal of the International Society on Toxinology
- Molecules (Basel, Switzerland)
- TheScientificWorldJournal
- Letters in applied microbiology
- Journal of evidence-based complementary & alternative medicine
- Journal of arthropod-borne diseases
- Frontiers in microbiology
- Scientific reports
- International journal of microbiology
- Food & function
- Food chemistry
- Medical and veterinary entomology
- Critical reviews in microbiology
- Chemistry & biodiversity
- Asian Pacific journal of tropical biomedicine
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Oxidative medicine and cellular longevity
- Parkinson's disease
- Journal de mycologie medicale
- Fitoterapia
- Planta medica
- Pharmaceutical development and technology
- AMB Express
- Pathogens (Basel, Switzerland)
- Complementary therapies in medicine
- Journal of microbiology and biotechnology
- Journal of agricultural and food chemistry
CLOVE OIL
- Molecules (Basel, Switzerland)
- BMC plant biology
- Pakistan journal of pharmaceutical sciences
- Asian Pacific journal of allergy and immunology
- Journal of clinical and diagnostic research : JCDR
View 5 additional sources
- Evidence-based complementary and alternative medicine : eCAM
- Animals : an open access journal from MDPI
- Cellular and molecular biology (Noisy-le-Grand, France)
- Recent patents on drug delivery & formulation
- The Southeast Asian journal of tropical medicine and public health
Caryophyllene
- Dr. Duke
- BMC veterinary research
- Toxicology mechanisms and methods
- Food & function
- AMB Express
Gallic acid
- Dr. Duke
- Luminescence : the journal of biological and chemical luminescence
- Asian Pacific journal of tropical biomedicine
- PloS one
- Biomolecules
OLEANOLIC ACID
- Dr. Duke
- Oncology research
- Mediators of inflammation
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Chemical & pharmaceutical bulletin
quercetin
- Dr. Duke
- Frontiers in microbiology
- Scientific reports
- PloS one
- Biomolecules
Eugenol acetate
- Dr. Duke
- Frontiers in nutrition
- Antioxidants (Basel, Switzerland)
- Asian Pacific journal of tropical biomedicine
Flavonoids
- Journal of pharmaceutical and biomedical analysis
- BMC complementary medicine and therapies
- Antibiotics (Basel, Switzerland)
- AMB Express
Acetyl eugenol
- Dr. Duke
- Food & function
- Parkinson's disease
Isoeugenol
- Dr. Duke
- Advances in experimental medicine and biology
- Frontiers in nutrition
Activities
Syzygium aromaticum has 597 reported activities identified across 15 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Anticancer, Antimicrobial, Antifungal.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 20 supporting sources | ★★★★★ |
| Antibacterial | 11 supporting sources | ★★★★★ |
| Anticancer | 10 supporting sources | ★★★★★ |
| Antimicrobial | 9 supporting sources | ★★★★☆ |
| Antifungal | 8 supporting sources | ★★★★☆ |
| Analgesic | 7 supporting sources | ★★★★☆ |
| Antiviral | 7 supporting sources | ★★★★☆ |
| Antiseptic | 5 supporting sources | ★★★☆☆ |
| Neuroprotective | 4 supporting sources | ★★☆☆☆ |
| Antinociceptive | 3 supporting sources | ★★☆☆☆ |
Antioxidant
- Dr. Duke
- Advances in experimental medicine and biology
- Scientific reports
- Frontiers in nutrition
- Plants (Basel, Switzerland)
View 15 additional sources
- Cancer biotherapy & radiopharmaceuticals
- Biomolecules
- Antioxidants (Basel, Switzerland)
- Molecules (Basel, Switzerland)
- Journal of pharmaceutical and biomedical analysis
- Toxicon : official journal of the International Society on Toxinology
- Food & function
- Dose-response : a publication of International Hormesis Society
- Critical reviews in microbiology
- Asian Pacific journal of tropical biomedicine
- Oxidative medicine and cellular longevity
- Parkinson's disease
- The Medical journal of Malaysia
- Pharmaceutical development and technology
- Journal of agricultural and food chemistry
Antibacterial
- Dr. Duke
- Antibiotics (Basel, Switzerland)
- Molecules (Basel, Switzerland)
- Scientific reports
- Biomolecules
View 6 additional sources
- Antioxidants (Basel, Switzerland)
- Toxicon : official journal of the International Society on Toxinology
- BMC complementary medicine and therapies
- Oncology research
- The Medical journal of Malaysia
- Animals : an open access journal from MDPI
Anticancer
- Dr. Duke
- Molecules (Basel, Switzerland)
- Cell biology international
- Cancer biotherapy & radiopharmaceuticals
- Beni-Suef University journal of basic and applied sciences
View 5 additional sources
- Biomolecules
- Antioxidants (Basel, Switzerland)
- Phytotherapy research : PTR
- Biomedicines
- Open life sciences
Antimicrobial
- Bioprocess and biosystems engineering
- Molecules (Basel, Switzerland)
- Antibiotics (Basel, Switzerland)
- Current medicinal chemistry
- Journal of clinical and diagnostic research : JCDR
View 4 additional sources
- Chemistry & biodiversity
- Asian Pacific journal of tropical biomedicine
- AMB Express
- Pathogens (Basel, Switzerland)
Antifungal
- Advances in dental research
- Molecules (Basel, Switzerland)
- Biomolecules
- Applied microbiology and biotechnology
- Antioxidants (Basel, Switzerland)
View 3 additional sources
- Oncology research
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Food science & nutrition
Analgesic
- Dr. Duke
- Frontiers in nutrition
- Biomolecules
- Antioxidants (Basel, Switzerland)
- Toxicon : official journal of the International Society on Toxinology
View 2 additional sources
- Mediators of inflammation
- Open life sciences
Antiviral
- Dr. Duke
- Cancer biotherapy & radiopharmaceuticals
- Biomolecules
- Molecules (Basel, Switzerland)
- Saudi journal of biological sciences
View 2 additional sources
- Oncology research
- Open life sciences
Antiseptic
- Dr. Duke
- Biomolecules
- Antioxidants (Basel, Switzerland)
- Oncology research
- Evidence-based complementary and alternative medicine : eCAM
Neuroprotective
- Dr. Duke
- Frontiers in nutrition
- Parkinson's disease
- Biomolecules
Antinociceptive
- Dr. Duke
- Evidence-based complementary and alternative medicine : eCAM
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Conditions
Syzygium aromaticum has 124 reported investigations on conditions identified across 15 scientific publications and several other databases. The most consistently reported conditions include Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, cancer, inflammation.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Staphylococcus aureus | 7 supporting sources | ★★★★☆ |
| Escherichia coli | 6 supporting sources | ★★★☆☆ |
| Pseudomonas aeruginosa | 6 supporting sources | ★★★☆☆ |
| Cancer | 6 supporting sources | ★★★☆☆ |
| Inflammation | 5 supporting sources | ★★★☆☆ |
| Oxidative stress | 5 supporting sources | ★★★☆☆ |
| Covid-19 | 4 supporting sources | ★★☆☆☆ |
| Streptococcus mutans | 4 supporting sources | ★★☆☆☆ |
| Toothache | 4 supporting sources | ★★☆☆☆ |
| Candida albicans | 3 supporting sources | ★★☆☆☆ |
Staphylococcus aureus
- Journal of intercultural ethnopharmacology
- Pharmaceutical biology
- Molecules (Basel, Switzerland)
- Plants (Basel, Switzerland)
- Frontiers in microbiology
View 2 additional sources
- Food science and biotechnology
- Life (Basel, Switzerland)
Escherichia coli
- Journal of intercultural ethnopharmacology
- Scientific reports
- Molecules (Basel, Switzerland)
- Frontiers in microbiology
- Chemistry & biodiversity
View 1 additional sources
- Journal of food protection
Pseudomonas aeruginosa
- Journal of intercultural ethnopharmacology
- Scientific reports
- Pharmaceutical biology
- Molecules (Basel, Switzerland)
- BMC complementary medicine and therapies
View 1 additional sources
- Chemistry & biodiversity
Cancer
- Advances in experimental medicine and biology
- Beni-Suef University journal of basic and applied sciences
- Phytotherapy research : PTR
- Oxidative medicine and cellular longevity
- Planta medica
View 1 additional sources
- Molecules (Basel, Switzerland)
Inflammation
- Food science & nutrition
- Naunyn-Schmiedeberg's archives of pharmacology
- Oxidative medicine and cellular longevity
- Dose-response : a publication of International Hormesis Society
- Inflammopharmacology
Oxidative stress
- Toxicon : official journal of the International Society on Toxinology
- Food & function
- Dose-response : a publication of International Hormesis Society
- Oxidative medicine and cellular longevity
- Biomolecules
Covid-19
- Protein and peptide letters
- Evidence-based complementary and alternative medicine : eCAM
- Molecules (Basel, Switzerland)
- Saudi journal of biological sciences
Streptococcus mutans
- Open access Macedonian journal of medical sciences
- Journal of ethnopharmacology
- 3 Biotech
- Nigerian medical journal : journal of the Nigeria Medical Association
Toothache
- Frontiers in nutrition
- Avicenna journal of phytomedicine
- Naunyn-Schmiedeberg's archives of pharmacology
- Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Candida albicans
- Scientific reports
- Molecules (Basel, Switzerland)
- Nigerian medical journal : journal of the Nigeria Medical Association
Preparations
Syzygium aromaticum has 55 reported preparations identified across 15 scientific publications and several other databases. The most consistently reported preparations include essential oils, essential oil, aqueous extract, extracts, water extracts.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Essential oils | 10 supporting sources | ★★★★★ |
| Essential oil | 6 supporting sources | ★★★☆☆ |
| Aqueous extract | 4 supporting sources | ★★☆☆☆ |
| Extracts | 4 supporting sources | ★★☆☆☆ |
| Water extracts | 3 supporting sources | ★★☆☆☆ |
| Eo | 2 supporting sources | ★☆☆☆☆ |
| Essential oils | 2 supporting sources | ★☆☆☆☆ |
| Clove oil | 2 supporting sources | ★☆☆☆☆ |
| Ethanol extract | 2 supporting sources | ★☆☆☆☆ |
| Ethanol extracts | 2 supporting sources | ★☆☆☆☆ |
Essential oils
- Journal of food protection
- Applied microbiology and biotechnology
- Parasitology research
- Tropical biomedicine
- Molecules (Basel, Switzerland)
View 5 additional sources
- Letters in applied microbiology
- BMC complementary and alternative medicine
- Journal of medicinal food
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Evidence-based complementary and alternative medicine : eCAM
Essential oil
- Pakistan journal of biological sciences : PJBS
- Plants (Basel, Switzerland)
- Naunyn-Schmiedeberg's archives of pharmacology
- Medical and veterinary entomology
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
View 1 additional sources
- Journal of ethnopharmacology
Aqueous extract
- BMC complementary and alternative medicine
- Phytotherapy research : PTR
- West African journal of pharmacology and drug research
- Pharmaceutical biology
Extracts
- Brazilian journal of otorhinolaryngology
- Journal of ethnopharmacology
- Evidence-based complementary and alternative medicine : eCAM
- Inflammopharmacology
Water extracts
- Phytotherapy research : PTR
- Journal of ethnopharmacology
- Journal of natural medicines
Eo
- Letters in applied microbiology
- Antibiotics (Basel, Switzerland)
Essential oils
- Journal de mycologie medicale
- Natural product research
Clove oil
- Biomolecules
- Asian Pacific journal of allergy and immunology
Ethanol extract
- West African journal of pharmacology and drug research
- Experimental and therapeutic medicine
Ethanol extracts
- Experimental & applied acarology
- Molecules (Basel, Switzerland)