Symphorema polyandrum
Symphorema polyandrum · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Symphorema polyandrum is a botanical species that has garnered significant scientific interest due to its diverse therapeutic potential. Research indicates that this plant exhibits notable anticancer and antioxidant activities, making it a subject of pharmacological study. Specifically, its biological effects are closely linked to the modulation of antioxidant levels and the regulation of IL-6. These beneficial properties are often investigated through the use of specialized preparations, including hydromethanolic and methanolic extracts. Consequently, understanding the chemical profile of these extracts is essential for exploring the plant's medicinal applications.
- Synonyms
- Not available
- Common names
- Not available
- Family
- Lamiaceae
- Distribution
- Asia-Temperate
- Plant Parts
- Not available
Classification
Taxonomy
Symphorema polyandrum is a distinctive botanical species belonging to the kingdom Plantae. Within this vast biological realm, it is specifically classified under the class Equisetopsida. The plant is further organized into the order Lamiales, showcasing its unique evolutionary lineage. It falls under the family Lamiaceae, a group known for its diverse and aromatic characteristics. Finally, this species is defined by its placement within the genus Symphorema.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Lamiales |
| Family | Lamiaceae |
| Genus | Symphorema |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Symphorema polyandrum is a distinctive botanical species primarily found throughout the tropical regions of Asia. Its natural distribution spans a significant portion of the Indian Subcontinent, making it a notable component of the local flora. Within the diverse ecosystems of India, this plant thrives amidst a variety of humid and warm environments. Understanding its specific geographic range provides valuable insight into the ecological patterns of the region. Consequently, this species serves as an important indicator of the rich biodiversity present in these tropical landscapes.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Biological Activities
Symphorema polyandrum, a member of the Lamiaceae family also known as Badichang, has demonstrated significant therapeutic potential through recent scientific investigation. Research involving methanolic extracts of the plant has revealed substantial antioxidant activity, which is linked to its rich phenolic and flavonoid content. Furthermore, the plant exhibits potent anticancer properties, specifically showing antiproliferative activity against MDA-MB-231 triple-negative breast cancer cells. This anticancer effect is achieved by promoting nuclear fragmentation and condensation in cancer cells without harming normal fibroblast cells. Ultimately, these findings highlight the dual antioxidant and anticancer capabilities of S. polyandrum as a promising medicinal resource.
Compounds
Conditions
Symphorema polyandrum exhibits significant anticancer properties, specifically demonstrating substantial antiproliferative activity against MDA-MB-231 triple-negative breast cancer cells. This medicinal plant also functions as an anti-inflammatory agent by effectively lowering the levels of proinflammatory cytokines. Specifically, it treats inflammation by reducing the presence of IL-6 within the studied models. Additionally, the plant treats the levels of TNF-α to mitigate inflammatory responses. These combined biological activities highlight its therapeutic potential in addressing both cancer and inflammatory conditions.
Preparations
Symphorema polyandrum is prepared as both hydromethanolic and methanolic extracts through the use of Soxhlet extraction. These specific preparations are utilized to quantify the plant's total phenolic and flavonoid contents. The methanolic extracts of the plant are further analyzed using UPLC-ESI-QTOF-MS to identify key phytochemical constituents. Researchers specifically focused on these extract types to investigate the plant's antioxidant, anticancer, and anti-inflammatory properties. Consequently, the methanolic extract of the species has demonstrated significant biological activities, including potent antioxidant and antiproliferative effects.