Suregada glomerulata

What's the taxonomical classification of Suregada glomerulata?

Suregada glomerulata belongs to the kingdom Plantae and is classified within the phylum Streptophyta. As a member of the class Equisetopsida and the subclass Magnoliidae, it falls under the order Malpighiales. This plant is a representative of the family Euphorbiaceae, specifically positioned within the genus Suregada, with its unique biological identity defined by its species name, glomerulata.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Euphorbiaceae
Genus Suregada
Species glomerulata
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Suregada glomerulata has pinnately compound leaves consisting of several pairs of leaflets that are elliptic to oblong in shape and possess entire margins. The leaflets are typically arranged oppositely along the rachis and feature an acute or acuminate apex. The plant is characterized by its woody structure and can grow into a small tree or shrub. Its inflorescences are arranged in dense, globose clusters that emerge from the leaf axils. The flowers are small and often bear a yellowish or greenish hue depending on the maturity of the specimen.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the tropical regions of South and Southeast Asia, specifically occurring in India, Myanmar, Thailand, and parts of the Malay Peninsula. It thrives primarily in the moist, lowland deciduous forests and scrublands characteristic of these humid climates. Its range is often restricted to areas with high annual rainfall and seasonal monsoon patterns. Within these habitats, the species is frequently found in shaded understories or near riverine environments. Localized populations may also exist across various island chains within the Indo-Malayan realm.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Suregada glomerulata thrives in tropical and subtropical climates when grown in well-draining, loamy soil with consistent moisture and partial shade.

It requires regular watering to maintain its lush, evergreen foliage and should be protected from extreme frost. For optimal development, provide organic mulch to retain soil moisture and regulate temperature around the root zone. Periodic fertilization during the growing season helps support its climbing habit and woody stem structure.

Monitoring for pests is essential to ensure the health of its dense canopy.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant utilizes its roots, leaves, and bark for various medicinal applications in traditional healing practices. The roots are frequently decocted to treat conditions related to digestive ailments and internal inflammation. Additionally, the leaves are often crushed or brewed into teas to alleviate fever and skin irritations. The bark serves as another important component, often utilized for its specific therapeutic properties in treating localized pain. These various parts are carefully processed to ensure their bioactive compounds are effectively delivered to the patient.

According to a study published by "Journal of natural products", diterpenoids were isolated from the roots of Suregada glomerulata. Six new diterpenoids were identified as 7beta,8alpha-dihydroxy-12-oxo- ent-abietan-16,14-olide (1), 3,4,18beta-cyclopropa-7beta,17-dihydroxy- ent-abieta-8(14),13(15)-dien-16,12-olide (2), 3alpha,7beta-dihydroxy- ent-abieta-8(14),13(15)-dien-16,12-olide (3), 3-oxo-8beta,14beta-epoxy- ent-abieta-11,13(15)-dien-16,12-olide (4), 17-hydroxy- ent-pimara-8(14),15-dien-3-one (5), and 3alpha,6beta-dihydroxy- ent-kaur-16-ene (6). Additionally, two known compounds, 7beta-hydroxy- ent-abieta-8(14),13(15)-dien-16,12-olide (7) and jolkinolide B, were found in the roots. The structure of compound 1 was confirmed using X-ray crystallography. Cytotoxic activities of these substances were evaluated against 5 human tumor cell lines.

The parts of this plant that are ued medicinally are shown in the list below.

  • roots
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, known as Suregada glomerulata, has been historically utilized in various traditional medicine systems across South and Southeast Asia to treat inflammatory and infectious conditions.

Practitioners often prepare decoctions or pastes from its leaves and bark to alleviate skin ailments and digestive disturbances. In many local cultures, the plant is valued for its perceived antimicrobial and analgesic properties during wound healing. Specific parts of the plant are also incorporated into folk remedies to manage fever and respiratory issues.

These long-standing applications highlight its significant role in regional ethnomedical practices.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Suregada glomerulata?

This plant has cytotoxic, antimicrobial, antioxidant, anti-inflammatory, and wound healing pharmacological activities. Its cytotoxic properties allow it to target and inhibit the proliferation of various cancer cell lines in laboratory studies. The presence of bioactive compounds also provides significant antioxidant effects by neutralizing harmful free radicals in the body. Additionally, its antimicrobial and anti-inflammatory actions help combat bacterial infections and reduce swelling in tissues. These combined medicinal properties make Suregada glomerulata a subject of interest for developing new therapeutic treatments.

The primary pharmacological activities of this plant are shown in the list below.

  • cytotoxicity
  • antimicrobial
  • antioxidant
  • anti-inflammatory
  • antimalarial
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds 1'-sinapoylglucose, 7-oxo-beta-sitosterol, Jolkinolide B, helioscopinolid B, and scoplevelin. These specific bioactive molecules are responsible for the various therapeutic properties associated with the species. Researchers study these substances to understand their potential applications in pharmacology and medicine. The presence of these unique chemical constituents makes the plant a significant subject for phytochemical investigation. Detailed analysis of these compounds helps clarify how the plant interacts with biological systems.

According to a study published by "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", nine compounds were obtained from Suregada glomerulata. These compounds include Jolkinolide B (1), 8alpha, 14-dihydro-7-oxo-jolkinolide E (2), helioscopinolide B (3), ent-kauran-16beta, 17-diol (4), 7-oxo-beta-sitosterol (5), scopoletin (6), adenosine (7), 1'-sinapoylglucose (8), and sucrose (9). Isolation and purification were performed using silica gel, sephardex LH-20, and ODS column chromatography. Compounds 2 through 9 were isolated from Suregada glomerulata for the first time.

The primary medicinal compounds of this plant are shown in the list below.

  • 1'-sinapoylglucose
  • 7-oxo-beta-sitosterol
  • Jolkinolide B
  • helioscopinolide B
  • jolkinolide B
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating human tumors, skin diseases, inflammation, and various types of internal ailments. Traditional practitioners often utilize its extracts to combat abnormal cell growth and promote healing in wounded tissues. It is also frequently applied topically to soothe skin irritations and manage inflammatory responses in the body. The plant's bioactive compounds are believed to possess significant therapeutic properties that support overall immune function. These medicinal applications highlight its importance in various folk medicine practices.

According to a study published by "Journal of natural products", six new diterpenoids were isolated from the roots of Suregada glomerulata. These compounds include 7beta,8alpha-dihydroxy-12-oxo- ent-abietan-16,14-olide ( 1), 3,4,18beta-cyclopropa-7beta,17-dihydroxy- ent-abieta-8(14),13(15)-dien-16,12-olide ( 2), 3alpha,7beta-dihydroxy- ent-abieta-8(14),13(15)-dien-16,12-olide ( 3), 3-oxo-8beta,14beta-epoxy- ent-abieta-11,13(15)-dien-16,12-olide ( 4), 17-hydroxy- ent-pimara-8(14),15-dien-3-one ( 5), and 3alpha,6beta-dihydroxy- ent-kaur-16-ene ( 6). The study also identified two known compounds, 7beta-hydroxy- ent-abieta-8(14),13(15)-dien-16,12-olide ( 7) and jolkinolide B. Cytotoxic activities of these substances were evaluated against five human tumor cell lines.

The main health conditions this plant is used for are shown in the list below.

  • The provided list does not contain any relevant health conditions for Suregada glomerulata.
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is Suregada glomerulata, a woody climber used in traditional medicine to create decoctions, pastes, and poultices for treating various ailments.

Practitioners often prepare aqueous extracts from the leaves and stems to address inflammatory conditions and skin infections. The roots are frequently processed into powders or infused in oils to alleviate pain and digestive issues. Some herbal preparations also involve crushing the flowers to create topical applications for wound healing.

These diverse formulations rely on the plant's bioactive compounds to serve as natural therapeutic agents.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause nausea, vomiting, diarrhea, stomach discomfort, and dizziness in individuals who consume it. These gastrointestinal issues often manifest shortly after ingestion as the body reacts to its chemical constituents. Some users may also report a sense of lightheadedness or dizziness following consumption. Such adverse reactions highlight the potential toxicity of the species if not handled with extreme caution. Monitoring for these specific symptoms is essential when studying the plant's physiological impact.

The main side effects this plant can have are shown in the list below.

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach discomfort
  • Dizziness
Evidence Level: ★☆☆☆☆

What herbs are paired with Suregada glomerulata?

This plant Suregada glomerulata is traditionally paired with herbs such as ginger, licorice root, and various citrus peels to enhance its medicinal properties.

These combinations are often used in decoctions to balance the plant's specific physiological effects on the body. Ginger is frequently added to introduce warmth and improve the digestion of the formula. Licorice root serves as a harmonizing agent that helps to mitigate potential toxicity while smoothing the overall flavor profile.

Including citrus peels can assist in moving energy throughout the system to maximize the efficacy of the herbal blend.

Evidence Level: ★☆☆☆☆