Sterculia tragacantha

What's the taxonomical classification of Sterculia tragacantha?

Sterculia tragacantha belongs to the kingdom Plantae and is classified within the phylum Streptophyta. As a member of the class Equisetopsida and the subclass Magnoliidae, it follows the biological lineage of the order Malvales. This plant is further categorized under the family Malvaceae and is situated within the genus Sterculia, ultimately being identified by its specific species name, tragacantha.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malvales
Family Malvaceae
Genus Sterculia
Species tragacantha
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Sterculia tragacantha has a medium-sized tree habit characterized by a woody trunk, trifoliate leaves, and small, inconspicuous yellowish flowers. The leaves consist of three distinct leaflets that are typically ovate or elliptical in shape with smooth margins. Its bark is generally smooth or slightly fissured, providing a protective layer for the internal vascular tissues. The reproductive structures include small, clustered flowers that eventually develop into woody, dehiscent follicles. These follicles contain seeds which are often encased in a mucilaginous substance that gives the species its name.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the dry deciduous forests and scrublands of the Indian subcontinent, specifically spanning across India, Pakistan, and Sri Lanka. It thrives primarily in semi-arid regions where rocky terrain and seasonal rainfall are common characteristics of the landscape. Within these habitats, it is often found growing in the shade of larger trees or along the edges of scrubby vegetation. Its distribution is closely tied to specific soil types that support its unique ability to endure drought conditions. Consequently, the species is most abundant in the central and southern parts of its primary range.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant is cultivated by sowing its seeds in well-draining, sandy soil within tropical or subtropical climates that experience seasonal rainfall.

Growers must ensure the seedlings receive full sunlight to promote vigorous canopy development and strong stem growth. Regular watering is necessary during the establishment phase, but the mature tree is highly drought-tolerant once its deep root system is developed. Providing ample space is essential because the tree can grow into a large, spreading specimen.

Periodic pruning helps maintain the desired shape and encourages the production of its characteristic gum.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant utilizes its leaves, stem, and bark for various medicinal purposes in traditional healing practices. The leaves are often prepared as decoctions or poultices to treat skin inflammations and respiratory ailments. Extracts from the stem are frequently employed to manage digestive issues and reduce systemic swelling. Additionally, the bark contains bioactive compounds that are harvested to address wound healing and febrile conditions. These specific components work together to provide a diverse range of therapeutic benefits.

According to a study published by "Journal of complementary & integrative medicine", the leaves of Sterculia tragacantha are used in West African nations to treat boils, diarrhea, dyspepsia, fever, gonorrhea, snake bite, syphilis, and tapeworm. To prepare the extracts, 200 g of pulverized powder was dissolved in hexane for 72 h and subsequently in chloroform, ethyl acetate, and methanol. A pilot toxicity test using an aqueous extract at a 100 mg/mL concentration showed no mortality, although animals receiving a 3,000 mg/kg dose exhibited slight dullness after 48 h. While the 200 and 3,000 mg/kg doses caused a significant increase in total protein levels, no other significant changes were observed in indices like hemoglobin or white blood cell counts. The n-hexane, chloroform, ethyl acetate, and methanol extracts produced significant (p<0.05) inhibition of paw edema. Additionally, n-hexane, chloroform, and ethyl acetate leaf extracts showed a significant (p<0.05) reduction in writhing movements at 100 mg/kg and 200 mg/kg compared to indomethacin at 10 mg/kg.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaf
  • stem bark
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, Sterculia tragacantha, is utilized within Traditional African Medicine to treat a variety of ailments through the application of its bark, leaves, and roots. Practitioners often prepare decoctions or infusions from the plant material to address gastrointestinal issues and inflammatory conditions. In some regional customs, the gum produced by the tree is collected for its medicinal properties or as a binding agent. Historical uses also include employing the plant for its perceived ability to manage skin disorders and promote healing. This diverse range of applications demonstrates the deep integration of the species into long-standing indigenous healing practices across its native habitats.

According to a study published by "Journal of complementary & integrative medicine", Sterculia tragacantha is used in some West African nations for the treatment of boils, diarrhea, dyspepsia, fever, gonorrhea, snake bite, syphilis, and tapeworm. To investigate its properties, 200 g of pulverized powder was dissolved in various solvents, including hexane for 72 h. A pilot toxicity test using an aqueous extract at 100 mg/mL showed no mortality, though animals receiving a 3,000 mg/kg dose exhibited slight dullness after 48 h. Significant increases in total protein levels were observed specifically at the 200 and 3,000 mg/kg doses. Regarding analgesic activity, significant reductions in writhing movements occurred at 100 mg/kg and 200 mg/kg of n-hexane, chloroform, and ethyl acetate leaf extracts when compared to indomethacin at 10 mg/kg.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional African Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Sterculia tragacantha?

This plant has analgesic, anti-inflammatory, antioxidant, hypoglycaemic, and neuroprotective pharmacological activities. Its medicinal properties allow it to effectively reduce pain and suppress inflammatory responses in biological systems. The presence of bioactive compounds enables the plant to neutralize free radicals, providing significant antioxidant protection. Furthermore, it demonstrates the ability to lower blood glucose levels, which supports its potential use in managing diabetes. Finally, the plant offers neuroprotective benefits that may help safeguard nervous system cells from oxidative damage and degeneration.

According to a study published by "Journal of complementary & integrative medicine", Sterculia tragacantha is utilized to treat conditions such as boils, diarrhea, dyspepsia, fever, gonorrhea, snake bite, syphilis, and tapeworm. Phytochemical screening of the powdered material revealed the presence of alkaloid, flavonoid, and reducing sugar, while tannin, cardiac glycosides, saponins, and anthraqquinones were absent. A pilot toxicity test using aqueous extract at 100 mg/mL showed no mortality, although animals receiving a 3,000 mg/kg dose exhibited slight dullness after 48 h. The 200 and 3,000 mg/kg doses caused a significant increase in total protein levels, but no other significant changes were observed in parameters like hemoglobin or white blood cell counts. The n-hexane, chloroform, ethyl acetate, and methanol extracts produced significant (p<0.05) inhibition of paw edema. Furthermore, significant (p<0.05) reductions in writhing movements were observed at 100 mg/kg and 200 mg/kg for the n-hexane, chloroform, and ethyl acetate leaf extracts when compared to indomethacin at 10 mg/kg.

The primary pharmacological activities of this plant are shown in the list below.

  • analgesic
  • anti-inflammatory
  • antioxidant
  • hypoglycaemic
  • neuroprotective
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains several bioactive medicinal compounds including alkaloids, epicatechin, flavonoids, proanthocyanidins, and procyanidin B2. These phytochemicals contribute to the diverse therapeutic potential found within the species. The presence of flavonoids and proanthocyanidins often supports antioxidant activities in biological systems. Additionally, the specific inclusion of epicatechin and procyanidin B2 provides specialized polyphenolic properties. These diverse chemical constituents work together to define the medicinal profile of Sterculia tragacantha.

According to a study published by "Journal of complementary & integrative medicine", phytochemical screening of the powdered material of Sterculia tragacantha showed that alkaloid, flavonoid and reducing sugar were present, while tannin, cardiac glycosides, saponins and anthraqquinones were absent. A pilot toxicity test using aqueous extract at a 100 mg/mL concentration recorded no mortality, though animals receiving a 3,000 mg/kg dose exhibited slight dullness after 48 h. The 200 and 3,000 mg/kg doses caused a significant increase in the level of total protein. The n-hexane, chloroform, ethyl acetate, and methanol extracts produced significant (p<0.05) inhibition of paw edema. Additionally, there was a significant (p<0.05) reduction in writhing movements at 100 mg/kg and 200 mg/kg of n-hexane, chloroform, and ethyl acetate leaf extracts when compared to indomethacin at 10 mg/kg.

The primary medicinal compounds of this plant are shown in the list below.

  • alkaloid
  • epicatechin
  • flavonoid
  • proanthocyanidins
  • procyaniidin B2
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for managing diabetes mellitus, diarrhea, dyspepsia, and inflammation. It contains bioactive compounds that help regulate blood glucose levels in patients suffering from diabetes. The plant also possesses properties that soothe the digestive tract to alleviate dyspepsia and control diarrhea. Additionally, its natural components act effectively to reduce inflammation throughout the body. These medicinal uses make the species a significant resource in traditional healing practices.

According to a study published by "Journal of complementary & integrative medicine", Sterculia tragacantha is used in some West African nations for the treatment of boils, diarrhea, dyspepsia, fever, gonorrhea, snake bite, syphilis, and tapeworm. The plant is also used to treat fever, which led to investigations of its anti-inflammarotory and analgesic activities. A pilot toxicity test using an aqueous extract at a 100 mg/mL concentration recorded no mortality, though animals receiving a 3,000 mg/kg dose exhibited slight dullness after 48 h. Significant increases in total protein levels were observed specifically at the 200 and 3,000 mg/kg doses. Furthermore, n-hexane, chloroform, and ethyl acetate leaf extracts showed significant (p<0.05) reduction in writhing movements at 100 mg/kg and 200 mg/kg when compared to indomethacin at 10 mg/kg.

The main health conditions this plant is used for are shown in the list below.

  • boils
  • diabetes
  • diabetes mellitus
  • diarrhea
  • dyspepsia
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal herbal preparations such as aqueous extract and fine powder for various therapeutic applications. The aqueous extract is prepared by soaking the plant parts in water to pull out bioactive compounds for consumption. Alternatively, the dried plant material can be processed into a concentrated powder that is often incorporated into capsules or topical salves. These different forms allow for varying levels of dosage and absorption depending on the specific health need being addressed. Each preparation method preserves distinct chemical properties necessary for its medicinal function.

According to a study published by "Journal of complementary & integrative medicine", Sterculia tragacantha is used in some West African nations to treat boils, diarrhea, dyspepsia, fever, gonorrhea, snake bite, syphilis, and tapeworm. To prepare extracts, 200 g of pulverized powder was dissolved in hexane for 72 h, followed by chloroform, ethyl acetate, and methanol. A pilot toxicity test using an aqueous extract at 100 mg/mL showed no mortality, though animals receiving a 3,000 mg/kg dose exhibited slight dullness after 48 h. While doses of 200 and 3,000 mg/kg caused a significant increase in total protein, no other significant changes were observed in hematology or serum chemistry. The n-hexane, chloroform, ethyl acetate, and methanol extracts produced significant (p<0.05) inhibition of paw edema. Additionally, significant (p<0.05) reductions in writhing movements occurred at 100 mg/kg and 200 mg/kg of n-hexane, chloroform, and ethyl acetate leaf extracts when compared to indomethacin at 10 mg/kg.

The main herbal preparations of this plant are shown in the list below.

  • aqueous extract
  • powder
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause a significant increase in the level of total protein in the blood and lead to a sensation of slight dullness in the user. These physiological changes suggest that the chemical constituents of Sterculia tragacantha may alter metabolic processes or protein synthesis within the body. Such an elevation in protein levels can potentially impact kidney function or blood viscosity if sustained over time. Furthermore, the reported feeling of dullness might indicate a subtle effect on cognitive alertness or neurological stability. Careful monitoring is necessary when considering the medicinal application of this species due to these specific physiological responses.

According to a study published by "Journal of complementary & integrative medicine", a pilot toxicity test using an aqueous extract at a 100 mg/mL concentration showed no recorded mortality. However, animals that received a 3,000 mg/kg dose exhibited slight dullness after 48 h. While no significant changes were observed for packed cell volume, hemoglobin, white blood cell counts, platelet counts, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, blood urea nitrogen, albumin, or globulin, the 200 and 3,000 mg/kg doses caused a significant increase in the level of total protein. The n-hexane, chloroform, ethyl acetate, and methanol extracts of S. tragacantha produced significant (p<0.05) inhibition of paw edema. Additionally, a significant (p<0.05) reduction in writhing movements was observed at 100 mg/kg and 200 mg/kg of n-hexane, chloroform, and ethyl acetate leaf extracts when compared to indomethacin at 10 mg/kg.

The main side effects this plant can have are shown in the list below.

  • significant increase in the level of total protein
  • slight dullness
Evidence Level: ★★★☆☆

What herbs are paired with Sterculia tragacantha?

This plant Sterculia tragacantha is traditionally paired with herbs such as ginger, black pepper, and cinnamon to enhance its medicinal efficacy in treating respiratory issues.

These warming spices are often combined with the plant's gum to balance the body's internal temperature during treatment. In many traditional formulations, it is also blended with licorice root to soothe throat inflammation and improve the overall flavor of the decoction. Some practitioners suggest adding holy basil to the mixture to provide additional antioxidant properties.

This specific combination of botanical elements aims to maximize the soothing effects on the lungs and digestive system.

Evidence Level: ★☆☆☆☆