Soymida febrifuga

Soymida febrifuga · Accepted scientific name

Scientific literature: Very Sparse (5 studies) · ★☆☆☆☆

Soymida febrifuga is a versatile medicinal plant recognized for its significant therapeutic potential in treating fever and various infections. Research into its biological activities has revealed potent antiplasmodial, antimicrobial, antioxidant, and cytotoxic properties. The plant's leaves and roots serve as primary sources for bioactive compounds, including methyl angolensate and luteolin 7-O-glucoside. Studies focusing on the crude extract of the root callus demonstrate its effectiveness against Aspergillus fumigatus and its role in addressing cancer. Consequently, this species remains a subject of intense interest for its ability to combat oxidative stress and diverse pathological conditions.

Quick facts
Synonyms
Swietenia Febrifuga
Common names
Not available
Family
Meliaceae
Distribution
Not available
Plant Parts
Leaf · Root

Classification

Common Names

Soymida febrifuga is a botanical species known by several distinct regional names. In many areas, it is frequently referred to by the common name Indian Red Wood. It is also widely recognized under the alternative label of Indian-redwood. In certain linguistic contexts, the plant is identified as sojmida protihorúčková. Understanding these various names is essential for accurate identification and study of the species.

Sources: Catalogue of Life (COL)

Synonyms

Soymida febrifuga is a botanical species that is frequently identified by its alternative nomenclature. In many scientific texts and historical records, it is listed under the synonym Swietenia febrifuga. This taxonomic overlap can sometimes lead to confusion for researchers navigating various botanical databases. Recognizing both names is essential for ensuring accurate identification and consistent documentation within the field of plant studies. Understanding these linguistic relationships allows for a more seamless transition between different botanical classifications.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Soymida febrifuga is a distinctive species belonging to the kingdom Plantae. Within this vast kingdom, it is classified under the class Equisetopsida. Its taxonomic journey continues through the order Sapindales, which helps define its biological characteristics. This plant is a proud member of the genus Soymida, highlighting its unique evolutionary lineage. Finally, it finds its specific placement within the Meliaceae family.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Meliaceae
Genus Soymida

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Soymida febrifuga is a plant species with a broad geographic reach across several key regions of Asia. It is widely distributed throughout the tropical areas of the Indian Subcontinent, including significant presence in India and Bangladesh. The species also extends its range to the island nation of Sri Lanka. Beyond the subcontinent, its habitat encompasses the Indo-China region, specifically within Myanmar. This diverse distribution highlights the plant's adaptability to various tropical environments across the continent.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Soymida febrifuga is a self-supporting species characterized by its distinct tree growth form. This plant can reach a maximum height of 25 meters as it matures in its natural habitat. Its robust structure allows it to stand firmly without the need for external support.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Soymida febrifuga is a traditional Indian medicinal plant that has demonstrated a diverse range of significant pharmacological activities. Research indicates that its extracts possess potent antiplasmodial properties, making it a species of particular interest for antimalarial studies. Furthermore, the plant has been confirmed to exhibit strong antioxidant and antimicrobial activities against various bacterial and fungal strains. Beyond these effects, specific compounds derived from its roots, such as methyl angolensate, have shown notable cytotoxic properties. These findings suggest that the plant holds great potential as a source for developing new treatments for infections and cancer.

Compounds

Soymida febrifuga, a medicinal tree endemic to India, serves as a rich source of several bioactive compounds. Research involving the plant's root callus cultures has successfully isolated methyl angolensate and luteolin 7-O-glucoside through chromatographic processes. Methyl angolensate has demonstrated significant potential as a chemotherapeutic agent by inducing apoptosis in Daudi lymphoma cells. Furthermore, both isolated compounds exhibit notable antimicrobial properties, specifically targeting various bacterial and fungal strains. These findings highlight the pharmacological importance of the chemical constituents found within Soymida febrifuga.

Conditions

Soymida febrifuga demonstrates significant antimicrobial properties by effectively treating the fungal pathogens Aspergillus fumigatus, Candida albicans, and Candida tropicana. The plant's extracts, particularly the methanol version, show high potency against these specific microbial strains. Beyond antimicrobial activity, the plant yields methyl angolensate, a compound that exhibits cytotoxic effects against Burkitt's lymphoma cell lines. This natural product specifically induces apoptosis in Daudi cells through the activation of the mitochondrial pathway. Collectively, these findings highlight the plant's potential as both an antimicrobial agent and a chemotherapeutic candidate.

Preparations

Soymida febrifuga is prepared as a crude extract of the root callus to facilitate the identification of medicinal compounds. This specific extraction process allows researchers to isolate methyl angolensate, a plant-derived tetranortriterpenoid. Once purified from the root callus extract, this molecule is tested for its potential cytotoxic properties against cancer cell lines. The relationship between the plant's root callus and its crude extract is essential for discovering small molecules that affect lymphoma cell proliferation. Consequently, the preparation of the crude extract serves as the foundational step in evaluating the therapeutic potential of Soymida febrifuga.

Parts used

Soymida febrifuga is a medicinal plant that offers diverse therapeutic potential through different anatomical parts. Research into its leaves has revealed significant antioxidant and antimicrobial properties, particularly when using methanol or aqueous extracts. Beyond these functions, the plant's root callus serves as a valuable source for discovering specialized chemical compounds. Specifically, the tetranortriterpenoid methyl angolensate was purified from the root to study its effects on cancer cell lines. This compound has demonstrated a notable ability to induce apoptosis in Daudi cells, marking it as a potential candidate for chemotherapeutic development.