shrubby sophora
Sophora flavescens · Accepted scientific name
Scientific literature: Very Extensive (377 studies) · ★★★★★
Shrubby sophora, scientifically known as Sophora flavescens, is a perennial medicinal herb renowned in traditional Chinese medicine. Primarily utilized for its potent roots, this plant contains bioactive alkaloids that offer significant anti-inflammatory, antibacterial, and hepatoprotective properties, making it a vital resource in treating various skin and liver conditions.
- Family
- Fabaceae
- Native range
- Europe
- Parts used
- Root · Seed
- Common names
- Shrubby Sophora
- Scientific synonyms
- Radiusia Flavescens
Names and Synonyms
Common Names
- shrubby sophora
Scientific Names
Accepted name
Sophora flavescensSynonyms
- Radiusia flavescens
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Fabales, it is classified under the family Fabaceae. It is further identified by the genus Sophora, specifically as the species Sophora flavescens.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Fabales |
| Family | Fabaceae |
| Genus | Sophora |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a wide-ranging geographical distribution across various regions of Eurasia. In Northern Europe, its presence can be identified within Great Britain. The species is also extensively found throughout Siberia, specifically in the Altay, Chita, and Irkutsk regions. Furthermore, it extends into the Russian Far East, particularly in the Amur area. These diverse locations highlight the plant's ability to thrive in distinct northern and eastern habitats.
| Region | Area |
|---|---|
| Northern Europe | Great Britain |
| Siberia | Altay |
| Siberia | Chita |
| Siberia | Irkutsk |
| Russian Far East | Amur |
| Russian Far East | Khabarovsk |
| Russian Far East | Primorye |
| China | China South-Central |
| China | Hainan |
| China | Inner Mongolia |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Sophora flavescens is characterized by its ability to thrive in disturbed environments, most notably within crop fields where it often grows as a spontaneous or opportunistic species. In these agricultural settings, the plant adapts to the modified soil structures and varying nutrient availability typical of cultivated lands. Its presence in such habitats suggests a tolerance for anthropogenically influenced landscapes, allowing it to establish itself alongside primary crops. The ecological niche it occupies within these fields is often defined by its resilience to land management practices and its ability to utilize the open space and sunlight available in disturbed soil profiles.
- Habitat :
- crop fields
Life history
The life history of Sophora flavescens is characterized by its status as a perennial herb, allowing the plant to establish a long-term presence in its natural habitat through a robust underground root system. As a perennial species, it does not complete its life cycle in a single growing season but instead undergoes repeated cycles of vegetative growth and seasonal dormancy. The plant typically spends much of its energy developing a thick, tuberous taproot, which serves as a vital nutrient and water storage organ, enabling it to survive unfavorable environmental conditions and regrow during favorable seasons. Its developmental stages involve the emergence of compound leaves and the eventual production of inflorescences, leading to seed formation which facilitates dispersal and the establishment of new individuals within the ecosystem.
- Lifecycle :
- perennial
Morphology
The morphology of Sophora flavescens is characterized by its growth as a self-supporting herb with a woody structure. It typically exhibits a plant height ranging from a minimum of 0.5 m to a maximum of 0.7 m. Regarding its ecological habit, the plant is classified as terrestrial rather than aquatic or semiaquatic, and it functions as an independent organism without parasitic tendencies. As an epiphyte, it maintains a terrestrial existence, and its overall growth form is consistently identified as a herb.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Parasite :
- independent
- Plant height max:
- 0.7 m
- Plant height min:
- 0.5 m
- Woodiness :
- woody
Physiology
The physiology of Sophora flavescens is fundamentally characterized by a C3 photosynthetic pathway, a metabolic strategy common to most dicotyledonous woody shrubs and perennials. Under this pathway, the initial fixation of atmospheric carbon dioxide occurs through the enzyme Rubisco, resulting in the formation of a three-carbon compound, 3-phosphoglycerate. This carbon fixation process is integrated into the Calvin cycle to facilitate the synthesis of carbohydrates required for the plant's structural growth and the production of its characteristic secondary metabolites. The plant's physiological efficiency is closely tied to its stomatal conductance and transpiration rates, which regulate gas exchange and water use efficiency in response to environmental stressors. Furthermore, its metabolic framework supports the complex biosynthetic pathways necessary for the accumulation of bioactive alkaloids and flavonoids, which serve both as defense mechanisms and as key chemical constituents of the species.
- Photosynthetic pathway :
- C3
Reproduction
The reproduction of Sophora flavescens is characterized by a specific seasonal flowering cycle and highly consistent seed characteristics. The flowering period is concentrated in the month of July, marking a distinct window for pollination. Following the flowering stage, the plant produces seeds that exhibit remarkable uniformity in weight; the seed mass remains constant across all measured parameters, with a minimum, maximum, and mean mass all recorded at 0.03504 g. This precise seed mass suggests a highly stabilized reproductive output per individual seed.
- Flowering time :
- Jul
- Seed mass mean:
- 0.03504 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Sophora flavescens has 2 reported plant parts identified across 21 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, seed.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 20 supporting sources | ★★★★★ |
| Seed | 1 supporting sources | ★☆☆☆☆ |
Root
- Molecules (Basel, Switzerland)
- Phytotherapy research : PTR
- Pulmonary pharmacology & therapeutics
- Bioorganic chemistry
- Journal of natural products
View 15 additional sources
- Bioorganic & medicinal chemistry letters
- Journal of ethnopharmacology
- Plant physiology
- Scientific reports
- Yao xue xue bao = Acta pharmaceutica Sinica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Natural product research
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Planta medica
- BMC genomics
- Frontiers in microbiology
- Fitoterapia
- Archives of pharmacal research
- Scientific data
- Toxicology in vitro : an international journal published in association with BIBRA
Seed
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Chemicals
Sophora flavescens has 82 reported phytochemicals identified across 21 scientific publications and several other databases. The most consistently reported chemicals include Matrine, Oxymatrine, Flavonoids, Sophoraflavanone G, Kurarinone.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Matrine | 15 supporting sources | ★★★★★ |
| Oxymatrine | 14 supporting sources | ★★★★★ |
| Flavonoids | 9 supporting sources | ★★★★☆ |
| Sophoraflavanone G | 8 supporting sources | ★★★★☆ |
| Kurarinone | 7 supporting sources | ★★★★☆ |
| Sophoridine | 6 supporting sources | ★★★☆☆ |
| Trifolirhizin | 4 supporting sources | ★★☆☆☆ |
| Kushenol A | 3 supporting sources | ★★☆☆☆ |
| Maackiain | 3 supporting sources | ★★☆☆☆ |
| Oxysophocarpine | 3 supporting sources | ★★☆☆☆ |
Matrine
- Journal of ethnopharmacology
- Scientific reports
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Biological & pharmaceutical bulletin
View 10 additional sources
- Pharmaceuticals (Basel, Switzerland)
- Frontiers in pharmacology
- Molecular plant-microbe interactions : MPMI
- The American journal of Chinese medicine
- Frontiers in microbiology
- Molecules (Basel, Switzerland)
- Medical oncology (Northwood, London, England)
- Analytical and bioanalytical chemistry
- Letters in applied microbiology
- Journal of chromatography. A
Oxymatrine
- European journal of pharmacology
- Journal of ethnopharmacology
- Scientific reports
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
View 9 additional sources
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Pharmaceuticals (Basel, Switzerland)
- PloS one
- Medical science monitor : international medical journal of experimental and clinical research
- Frontiers in microbiology
- Analytical and bioanalytical chemistry
- OncoTargets and therapy
- Letters in applied microbiology
- Journal of chromatography. A
Flavonoids
- Yao xue xue bao = Acta pharmaceutica Sinica
- Journal of ethnopharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of leukocyte biology
- Fitoterapia
View 4 additional sources
- Frontiers in plant science
- Scientific data
- Chinese journal of natural medicines
- Chinese herbal medicines
Sophoraflavanone G
- Dr. Duke
- Molecules (Basel, Switzerland)
- Phytochemistry
- Natural product communications
- Journal of ethnopharmacology
View 3 additional sources
- Genes
- Journal of advanced research
- Analytical and bioanalytical chemistry
Kurarinone
- Journal of natural products
- Natural product communications
- Genes
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of advanced research
View 2 additional sources
- Analytical and bioanalytical chemistry
- Chinese herbal medicines
Sophoridine
- Journal of ethnopharmacology
- Scientific reports
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Pharmaceuticals (Basel, Switzerland)
- Frontiers in microbiology
View 1 additional sources
- Molecules (Basel, Switzerland)
Trifolirhizin
- Journal of natural products
- Scientific reports
- Molecules (Basel, Switzerland)
- International journal of molecular sciences
Kushenol A
- Molecules (Basel, Switzerland)
- Pulmonary pharmacology & therapeutics
- Genes
Maackiain
- Scientific reports
- Natural product research
- International journal of molecular sciences
Oxysophocarpine
- Journal of ethnopharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Pharmaceuticals (Basel, Switzerland)
Activities
Sophora flavescens has 33 reported activities identified across 21 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Antitumor, Estrogenic, Cytotoxic.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 5 supporting sources | ★★★☆☆ |
| Antibacterial | 4 supporting sources | ★★☆☆☆ |
| Antitumor | 4 supporting sources | ★★☆☆☆ |
| Estrogenic | 4 supporting sources | ★★☆☆☆ |
| Cytotoxic | 3 supporting sources | ★★☆☆☆ |
| Anticancer | 2 supporting sources | ★☆☆☆☆ |
| Antimicrobial | 2 supporting sources | ★☆☆☆☆ |
| Diuretic | 2 supporting sources | ★☆☆☆☆ |
| Abortifacient | 1 supporting sources | ★☆☆☆☆ |
| Anthelmintic | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Pharmaceuticals (Basel, Switzerland)
- Molecules (Basel, Switzerland)
- Journal of ethnopharmacology
- BMC genomics
- Chinese herbal medicines
Antibacterial
- Journal of ethnopharmacology
- Journal of natural products
- Antibiotics (Basel, Switzerland)
- BMC genomics
Antitumor
- Journal of ethnopharmacology
- BMC genomics
- Medical oncology (Northwood, London, England)
- Chinese herbal medicines
Estrogenic
- Dr. Duke
- Journal of natural products
- Environmental toxicology and pharmacology
- Phytotherapy research : PTR
Cytotoxic
- Dr. Duke
- Molecules (Basel, Switzerland)
- Toxicology in vitro : an international journal published in association with BIBRA
Anticancer
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Scientific reports
Antimicrobial
- Journal of ethnopharmacology
- Chinese herbal medicines
Diuretic
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Chinese herbal medicines
Abortifacient
- Dr. Duke
Anthelmintic
- Chinese herbal medicines
Medicinal Uses
Sophora flavescens has 67 reported medicinal uses identified across 21 scientific publications and several other databases. The most consistently reported uses include cancer, breast cancer, dysentery, antioxidant, asthma.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cancer | Frontiers in pharmacology (and other 4 sources) | ★★☆☆☆ |
| breast cancer | Journal of natural products (and other 3 sources) | ★★☆☆☆ |
| dysentery | Yao xue xue bao = Acta pharmaceutica Sinica (and other 3 sources) | ★★☆☆☆ |
| antioxidant | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| asthma | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| chronic hepatitis B | The American journal of Chinese medicine (and other 2 sources) | ★☆☆☆☆ |
| eczema | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| inflammation | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| jaundice | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| non-small cell lung cancer | Pulmonary pharmacology & therapeutics (and other 2 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| roots | Bioorganic chemistry (and other 2 sources) | ★☆☆☆☆ |
| traditional Chinese medicine | Molecules (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
| Aqueous extract | The American journal of Chinese medicine (and other 1 sources) | ★☆☆☆☆ |
| Cell suspension cultures | Phytochemistry (and other 1 sources) | ★☆☆☆☆ |
| Compound Kushen Injection (CKI) | Frontiers in oncology (and other 1 sources) | ★☆☆☆☆ |
| Dried root | Botanical studies (and other 1 sources) | ★☆☆☆☆ |
| Extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Herbal extracts | Journal of microbiology (Seoul, Korea) (and other 1 sources) | ★☆☆☆☆ |
| Kushen Tang | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| Kushen decoction | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |