Sophora flavescens

Shrubby sophora

Sophora flavescens, commonly known as Ku Shen, is a potent medicinal herb widely utilized in traditional Chinese medicine. Renowned for its bioactive alkaloids, particularly matrine, it possesses significant anti-inflammatory, antibacterial, and antipruritic properties. This plant is frequently employed to treat skin conditions, dampness, and various inflammatory ailments.

  • Scientific name: Sophora flavescens
  • Family: Fabaceae
  • Native range: Europe

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Fabales, it is classified under the family Fabaceae. It is further identified by the genus Sophora, specifically as the species Sophora flavescens.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Fabales WCVP
Family Fabaceae WCVP
Genus Sophora WCVP

Common Names

This plant, known scientifically as Sophora flavescens, is recognized by various common names across different regions and languages. In Mongolian, it is referred to as Лидэр, while in Chinese, it is widely known as 苦参 (zh-hans), 苦參 (zh-hant), and 苦參 (zh-hk). Additionally, in Japanese, the species is called クララ.
Language Common Name Source
mn Лидэр Wikidata
zh-hans 苦参 Wikidata
zh-hant 苦參 Wikidata
zh-hk 苦參 Wikidata
ja クララ Wikidata
ko 고삼 Wikidata
ru Софо́ра желтова́тая Wikidata
zh 苦参 Wikidata
bg жълта софора Wikidata
zh-tw 苦蔘 Wikidata

Distribution

This plant exhibits a wide-ranging geographical distribution across various regions of Eurasia. In Northern Europe, its presence can be identified within Great Britain. The species is also extensively found throughout Siberia, specifically in the Altay, Chita, and Irkutsk regions. Furthermore, it extends into the Russian Far East, particularly in the Amur area. These diverse locations highlight the plant's ability to thrive in distinct northern and eastern habitats.

Region Area Source
Northern Europe Great Britain WCVP
Siberia Altay WCVP
Siberia Chita WCVP
Siberia Irkutsk WCVP
Russian Far East Amur WCVP
Russian Far East Khabarovsk WCVP
Russian Far East Primorye WCVP
China China South-Central WCVP
China Hainan WCVP
China Inner Mongolia WCVP

Plant Parts

This plant, Sophora flavescens, is a medicinal species where the most pharmacologically significant part is the roots, which are harvested for their bioactive alkaloids. Within the anatomy of the root system, the internal vascular structure is essential for nutrient transport, consisting of the xylem which conducts water and minerals upward, and the phloem which distributes organic nutrients throughout the plant. Although the medicinal value is concentrated underground, the life cycle of the plant begins above ground, where the young cotyledon emerges during germination to provide the initial energy required for the seedling's development.
Total parts
18
Scientific sources
37
Plant Part Sources Confidence
roots 12 ★★★★★
root 7 ★★★★☆
xylem 2 ★☆☆☆☆
phloem 2 ★☆☆☆☆
young cotyledon 1 ★☆☆☆☆
seed 1 ★☆☆☆☆
rootstock 1 ★☆☆☆☆
root tissues 1 ★☆☆☆☆
root tip 1 ★☆☆☆☆
root systems 1 ★☆☆☆☆

Chemicals

Sophora flavescens has 84 reported phytochemicals identified across 152 scientific publications and several other databases. The most consistently reported chemicals include matrine, oxymatrine, flavonoids, kurarinone, sophoraflavanone G.

Total chemicals
84
Scientific sources
152

Most Reported Compounds

Compound Sources Confidence
matrine 15 ★★★★★
oxymatrine 10 ★★★★★
flavonoids 8 ★★★★☆
kurarinone 7 ★★★★☆
sophoraflavanone G 6 ★★★☆☆
sophoridine 6 ★★★☆☆
Oxymatrine 4 ★★☆☆☆
trifolirhizin 4 ★★☆☆☆
Matrine 3 ★★☆☆☆
maackiain 3 ★★☆☆☆

Activities

Sophora flavescens has 19 reported activities identified across 35 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Antitumor, Estrogenic, Anticancer.

Total activities
19
Scientific sources
35

Most Reported Activities

Activity Sources Confidence
Antioxidant 5 ★★★☆☆
Antibacterial 4 ★★☆☆☆
Antitumor 4 ★★☆☆☆
Estrogenic 3 ★★☆☆☆
Anticancer 2 ★☆☆☆☆
Antimicrobial 2 ★☆☆☆☆
Cytotoxic 2 ★☆☆☆☆
Diuretic 2 ★☆☆☆☆
Anthelmintic 1 ★☆☆☆☆
Anticarcinogenic 1 ★☆☆☆☆

Medicinal Uses

Sophora flavescens has 67 reported medicinal uses identified across 83 scientific publications and several other databases. The most consistently reported uses include cancer, breast cancer, dysentery, antioxidant, asthma.

Total uses
67
Scientific sources
83

Most Reported Uses

Use Sources Confidence
cancer 4 ★★☆☆☆
breast cancer 3 ★★☆☆☆
dysentery 3 ★★☆☆☆
antioxidant 2 ★☆☆☆☆
asthma 2 ★☆☆☆☆
chronic hepatitis B 2 ★☆☆☆☆
eczema 2 ★☆☆☆☆
inflammation 2 ★☆☆☆☆
jaundice 2 ★☆☆☆☆
non-small cell lung cancer 2 ★☆☆☆☆