Siraitia grosvenorii ex

Siraitia grosvenorii · Accepted scientific name

Scientific literature: Moderate (117 studies) · ★★★☆☆

Siraitia grosvenorii ex, scientifically known as Siraitia grosvenorii, is a remarkable medicinal plant prized in traditional healing practices. Renowned for its unique bioactive compounds, this species offers significant therapeutic potential. Understanding its botanical properties and pharmacological applications is essential for exploring its role in natural medicine and modern wellness.

Family
Cucurbitaceae
Native range
Asia-Temperate
Parts used
Fruit · Root
Common names
Buddhafruit · Arhatfruit · 1 more
Scientific synonyms
Thladiantha Grosvenorii · Momordica Grosvenorii

Names and Synonyms

Common Names

Scientific Names

Accepted name

Siraitia grosvenorii

Synonyms

Regional and Traditional Names

Spanish:

  • Siraitia
  • fruto del monje

German:

  • Luó Hàn Guǒ
  • Momordicae Grosvenori Fructus
  • Momordica grosvenorii
  • Mönchsfrucht

French:

  • Momordica grosvenorii
  • Thladiantha grosvenorii

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. It is further classified within the order Cucurbitaleales and the family Cucurbitaceae. Ultimately, its taxonomic identity is defined by its membership in the genus Siraitia.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Cucurbitales
Family Cucurbitaceae
Genus Siraitia

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific range across certain regions of East Asia. Its distribution is primarily concentrated within the borders of China. More specifically, it can be found growing throughout China South-Central. Additionally, the species is also located within China Southeast. These two distinct areas define its known geographical presence.

Region Area
China China South-Central
China China Southeast

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Morphology

The morphology of Siraitia grosvenorii is characterized by a diverse structural habit, where its woodiness is notably variable, ranging from woody to non-woody forms depending on the specific growth stage or environmental conditions. As a climbing or trailing vine, the plant typically develops elongated, flexible stems that can exhibit significant structural variation. The leaves are generally large, simple, and arranged in an opposite or sub-opposite pattern, often possessing a glossy texture with prominent venation. The reproductive structures consist of small, inconspicuous flowers that eventually develop into fleshy, globose or ovoid fruits. These fruits are typically characterized by a thick, greenish to brownish rind enclosing a sweet, pulpy interior containing numerous seeds, which is a defining morphological feature of the species.

Woodiness :
variable

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Siraitia grosvenorii has 4 reported plant parts identified across 24 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, root, leaf, seed.

Plant parts reported in Siraitia grosvenorii
Plant part Supporting sources Consensus
Fruit 19 supporting sources ★★★★★
Root 3 supporting sources ★★☆☆☆
Leaf 1 supporting sources ★☆☆☆☆
Seed 1 supporting sources ★☆☆☆☆

Fruit

  1. BMC genomics
  2. Journal of natural medicines
  3. Journal of pharmaceutical and biomedical analysis
  4. Journal of separation science
  5. PloS one
View 14 additional sources
  1. Molecules (Basel, Switzerland)
  2. Acta pharmaceutica Sinica. B
  3. Journal of chromatographic science
  4. Frontiers in pharmacology
  5. Foods (Basel, Switzerland)
  6. Phytochemistry
  7. The Journal of pharmacy and pharmacology
  8. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  9. Nature communications
  10. Frontiers in nutrition
  11. BMC complementary medicine and therapies
  12. International journal of molecular sciences
  13. Plants (Basel, Switzerland)
  14. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Root

  1. Frontiers in chemistry
  2. Phytochemistry
  3. International journal of molecular sciences

Leaf

  1. Journal of separation science

Seed

  1. Journal of pharmaceutical and biomedical analysis

Chemicals

Siraitia grosvenorii has 32 reported phytochemicals identified across 24 scientific publications and several other databases. The most consistently reported chemicals include Mogroside V, MOGROL, Mogroside IIe, triterpenoids, 2,3,22,23-Dioxidosqualene.

Chemicals reported in Siraitia grosvenorii
Chemical Supporting sources Consensus
Mogroside V 6 supporting sources ★★★☆☆
MOGROL 3 supporting sources ★★☆☆☆
Mogroside IIe 3 supporting sources ★★☆☆☆
triterpenoids 3 supporting sources ★★☆☆☆
2,3,22,23-Dioxidosqualene 2 supporting sources ★☆☆☆☆
Flavonoids 2 supporting sources ★☆☆☆☆
Lignans 2 supporting sources ★☆☆☆☆
Mogroside III 2 supporting sources ★☆☆☆☆
11-Oxo-Mogrol 1 supporting sources ★☆☆☆☆
11-Oxomogroside V 1 supporting sources ★☆☆☆☆

Mogroside V

  1. BMC genomics
  2. Molecules (Basel, Switzerland)
  3. Chinese herbal medicines
  4. Nature communications
  5. European journal of pharmacology
View 1 additional sources
  1. Frontiers in plant science

MOGROL

  1. Journal of chromatographic science
  2. Phytochemistry
  3. Scientific reports

Mogroside IIe

  1. Phytochemistry
  2. Nature communications
  3. Molecules (Basel, Switzerland)

triterpenoids

  1. Natural product research
  2. Frontiers in pharmacology
  3. Molecules (Basel, Switzerland)

2,3,22,23-Dioxidosqualene

  1. Plants (Basel, Switzerland)
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Flavonoids

  1. Frontiers in pharmacology
  2. Molecules (Basel, Switzerland)

Lignans

  1. Molecules (Basel, Switzerland)
  2. International journal of molecular sciences

Mogroside III

  1. Phytochemistry
  2. Molecules (Basel, Switzerland)

11-Oxo-Mogrol

  1. Natural product research

11-Oxomogroside V

  1. Scientific reports

Activities

Siraitia grosvenorii has 8 reported activities identified across 24 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Hepatoprotective, Hypoglycemic, Neuroprotective, Antiasthmatic.

Activities reported in Siraitia grosvenorii
Activity Supporting sources Consensus
Antioxidant 3 supporting sources ★★☆☆☆
Hepatoprotective 3 supporting sources ★★☆☆☆
Hypoglycemic 2 supporting sources ★☆☆☆☆
Neuroprotective 2 supporting sources ★☆☆☆☆
Antiasthmatic 1 supporting sources ★☆☆☆☆
Antimicrobial 1 supporting sources ★☆☆☆☆
Antitussive 1 supporting sources ★☆☆☆☆
Expectorant 1 supporting sources ★☆☆☆☆

Antioxidant

  1. Frontiers in pharmacology
  2. The Journal of pharmacy and pharmacology
  3. Molecules (Basel, Switzerland)

Hepatoprotective

  1. Frontiers in pharmacology
  2. Biomolecules
  3. Molecules (Basel, Switzerland)

Hypoglycemic

  1. Frontiers in pharmacology
  2. Molecules (Basel, Switzerland)

Neuroprotective

  1. The Journal of pharmacy and pharmacology
  2. European journal of pharmacology

Antiasthmatic

  1. Molecules (Basel, Switzerland)

Antimicrobial

  1. Frontiers in pharmacology

Antitussive

  1. Molecules (Basel, Switzerland)

Expectorant

  1. Molecules (Basel, Switzerland)

Medicinal Uses

Siraitia grosvenorii has 17 reported medicinal uses identified across 24 scientific publications and several other databases. The most consistently reported uses include asthma, obesity, Inflammation, NAFLD, antioxidant.

Most Reported Uses

Use Sources Consensus
asthma Biomolecules (and other 2 sources) ★☆☆☆☆
obesity Frontiers in nutrition (and other 2 sources) ★☆☆☆☆
Inflammation Biomolecules (and other 1 sources) ★☆☆☆☆
NAFLD Biomolecules (and other 1 sources) ★☆☆☆☆
antioxidant The Journal of pharmacy and pharmacology (and other 1 sources) ★☆☆☆☆
apoptosis European journal of pharmacology (and other 1 sources) ★☆☆☆☆
blood sugar Chinese herbal medicines (and other 1 sources) ★☆☆☆☆
constipation BMC complementary medicine and therapies (and other 1 sources) ★☆☆☆☆
cough Scientific reports (and other 1 sources) ★☆☆☆☆
depressive symptoms European journal of pharmacology (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
95% ethanol extract Chemistry & biodiversity (and other 1 sources) ★☆☆☆☆
Siraitia grosvenorii extract Journal of pharmaceutical and biomedical analysis (and other 1 sources) ★☆☆☆☆
aqueous extracts BMC complementary medicine and therapies (and other 1 sources) ★☆☆☆☆
extract The Journal of pharmacy and pharmacology (and other 1 sources) ★☆☆☆☆
fruit extract BMC genomics (and other 1 sources) ★☆☆☆☆
fruits Nature communications (and other 1 sources) ★☆☆☆☆
leaf extract Journal of separation science (and other 1 sources) ★☆☆☆☆