10 Possible Side Effects Of Scutellaria Lateriflora (Skullcap)

Scutellaria lateriflora has some side effects when used improperly, such as dizziness, nausea, and headaches.

These side effects are usually caused by taking high doses or using the herb in combination with other medications.

For instance, someone with a pre-existing condition like high blood pressure may experience worsened symptoms, potentially leading to hospitalization or limiting their daily activities, like working or exercising.

This article explains in details the 10 most common side effects of Scutellaria lateriflora if used imporperly.

1. Suppresses appetite

Scutellaria lateriflora causes allergic reactions in some individuals due to its chemical composition.

The plant contains a number of bioactive compounds, including flavonoids and phenolic acids, which can stimulate the immune system and cause an allergic response.

This reaction may manifest as symptoms such as hives, itching, and difficulty breathing, although in rare cases it can be more severe and even life-threatening.

2. Suppresses appetite

Scutellaria lateriflora induces sedative effects due to its ability to interact with the brain's neurotransmitters, particularly GABA and serotonin.

The herb's bioactive compounds, including flavonoids and alkaloids, bind to these neurotransmitter receptors, slowing down the transmission of signals and leading to a calming or sleep-inducing effect.

This sedative action can be beneficial for individuals experiencing anxiety or insomnia, but may also cause drowsiness or lethargy in some users.

3. Suppresses appetite

Scutellaria lateriflora increases drowsiness due to its sedative and calming effects on the nervous system.

The herb's active compounds, such as flavonoids and phenolic acids, can interact with GABA receptors in the brain, leading to a decrease in activity and an increase in feelings of relaxation and sleepiness.

This side effect is often more pronounced when taking high doses or combining skullcap with other sedative herbs or substances.

4. Suppresses appetite

Scutellaria lateriflora interferes with medication by altering its metabolic pathways.

The herb's flavonoids and phenolic acids may increase the activity of certain liver enzymes, leading to accelerated elimination or decreased efficacy of prescribed medications. This interaction can result in reduced therapeutic effects or increased risk of adverse reactions.

As Scutellaria lateriflora competes for cytochrome P450 enzyme systems, it may also enhance the metabolism of sensitive medications, potentially reducing their effectiveness.

5. Suppresses appetite

Scutellaria lateriflora triggers anxiety attacks due to its ability to affect the neurotransmitter GABA, which regulates calmness and relaxation.

The herb's potent sedative properties can sometimes cause an overactive response in some individuals, leading to increased anxiety levels.

Additionally, skullcap's potential to interact with certain medications that affect mood or behavior may also contribute to anxiety attacks.

6. Suppresses appetite

Scutellaria lateriflora hinders cognitive function by affecting the neurotransmitter receptors in the brain, particularly GABA and serotonin.

This can lead to feelings of confusion, disorientation, and difficulty concentrating or making decisions. The flavonoids and alkaloids present in Scutellaria lateriflora may interact with these neurotransmitters, causing a decrease in mental clarity and focus.

As a result, individuals may experience impaired cognitive function, which can impact their daily lives and abilities.

7. Suppresses appetite

Scutellaria lateriflora lowers blood pressure by interacting with the body's natural response to stress and anxiety.

As a natural relaxant, it can slow down heart rate and reduce blood vessel constriction, leading to a decrease in blood pressure.

Additionally, its flavonoid and iridoid compounds may block the effects of hormones that constrict blood vessels, further contributing to this side effect.

8. Suppresses appetite

Scutellaria lateriflora disrupts digestive system due to its ability to stimulate digestive enzymes and increase gut motility.

This can lead to symptoms such as nausea, diarrhea, or stomach cramps in some individuals.

The herb's bioactive compounds, including flavonoids and terpenoids, may also interact with certain medications or worsen pre-existing gastrointestinal conditions, exacerbating these unpleasant side effects.

9. Suppresses appetite

Scutellaria lateriflora enhances insomnia risk due to its ability to alter the body's natural sleep-wake cycles.

The herb contains flavonoids and diterpenes that interact with neurotransmitters in the brain, potentially disrupting normal sleep patterns.

As a result, individuals may experience difficulty falling asleep or staying asleep, leading to insomnia.

10. Suppresses appetite

Scutellaria lateriflora causes dry mouth by altering the body's natural balance of saliva production.

This is due to the herb's ability to stimulate the parasympathetic nervous system, which can slow down salivary gland function and reduce oral moisture. Additionally, Scutellaria lateriflora may also influence the activity of certain neurotransmitters involved in saliva secretion, leading to a temporary reduction in salivation.

As a result, some individuals may experience dry mouth as a side effect when using this herb.