Sambucus sieboldiana
Sambucus sieboldiana · Accepted scientific name
Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆
Sambucus sieboldiana is a deciduous shrub known for its diverse pharmacological potential in traditional medicine. Recent scientific investigations have focused on the medicinal properties of its stem to address complex physiological issues. Specifically, studies have explored the plant's efficacy in managing conditions related to bone resorption. Researchers evaluated these effects using both the methanolic extract and the ethyl acetate fraction (EtOAc Fr.) of the plant material. This targeted approach aims to uncover how specific chemical constituents influence bone density and remodeling processes.
- Synonyms
- Sambucus Sieboldiana Var. Pubescens · Sambucus Racemosa Var. Sieboldiana · 20 more
- Common names
- Not available
- Family
- Viburnaceae
- Distribution
- Not available
- Plant Parts
- Stem
Classification
Synonyms
Sambucus sieboldiana is a botanical species characterized by a complex web of taxonomic synonyms. Throughout various scientific classifications, it has been identified under the name Sambucus glabrescens. The plant also encompasses several distinct forms, such as Sambucus racemosa f. aurantiaca and Sambucus racemosa f. glaberrima. Furthermore, its identity is linked to the varieties Sambucus racemosa f. macrophylla and Sambucus racemosa f. nakaiana. Understanding these overlapping names is essential for accurate plant identification and study.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Sambucus sieboldiana is a remarkable botanical specimen belonging to the kingdom Plantae. This plant is classified under the class Equisetopsida and follows the structural order of Dipsacales. Within this taxonomic framework, it is a distinguished member of the genus Sambucus. Furthermore, it is categorized under the family Viburnaceae, which defines its unique biological characteristics. Understanding these specific relationships provides essential insight into the plant's place in the natural world.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Dipsacales |
| Family | Viburnaceae |
| Genus | Sambucus |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Sambucus sieboldiana is a resilient species primarily distributed across the temperate regions of Asia. Its presence is widely felt throughout Eastern Asia, spanning from the islands of Japan and the Nansei-shoto archipelago to the Korean Peninsula. The plant also extends its reach into the Russian Far East, finding suitable habitats in the Kuril Islands. Furthermore, it can be found thriving in the unique environments of Sakhalin. This broad geographical range highlights the plant's ability to adapt to various temperate climates across the continent.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Sambucus sieboldiana is a versatile shrub that adds significant structure to any landscape. This plant can reach a maximum height of 8 meters, making it a prominent feature in a garden.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Compounds
Sambucus sieboldiana serves as a rich source of various bioactive phenolic constituents that play a role in bone health. Research into the ethyl acetate fraction of its stems has identified several key compounds, including coniferyl alcohol, vanillic acid, and vanillin. These specific substances have demonstrated significant inhibitory effects on bone resorption stimulated by parathyroid hormone. Notably, vanillic acid was found to be particularly effective in preventing the decrease of bone mineral density in certain models. Ultimately, the presence of these compounds contributes to the plant's overall antiosteoporotic potential.
Conditions
Sambucus sieboldiana exhibits potent DPPH radical scavenging activity, as demonstrated by studies on spring mountain herbs. The plant's extracts effectively treat bone resorption both in vitro and in vivo. Specifically, it has been shown to treat PTH-stimulated bone resorption in neonatal mouse bones. Furthermore, the plant helps treat the decrease in bone mineral density in ovariectomized rats. Finally, Sambucus sieboldiana treats the elevated serum calcium levels observed in rats on a low calcium diet.
Preparations
Sambucus sieboldiana is prepared as a methanolic extract from its stems to study its inhibitory effects on bone resorption. This methanolic extract is further processed to be prepared as an ethyl acetate fraction (EtOAc Fr.) through guided fractionation. The resulting ethyl acetate fraction demonstrates a potent ability to inhibit PTH-stimulated bone resorption in neonatal mouse bones. Research indicates that the EtOAc Fr. of the plant is effective in vivo for preventing decreases in bone mineral density in ovariectomized rats. Ultimately, the biological activities observed in these preparations are linked to specific phenolic constituents found within the ethyl acetate fraction.
Parts used
Sambucus sieboldiana possesses medicinal properties that can be specifically derived from its stem. Research indicates that a methanolic extract from these stems contains bioactive compounds capable of inhibiting bone resorption. When fractionated, the ethyl acetate portion of the extract demonstrated significant potency in preventing the loss of bone mineral density in animal models. This protective effect is largely attributed to phenolic constituents such as vanillic acid, which plays a key role in suppressing bone degradation. Consequently, the stems of this plant represent a promising natural source for developing antiosteoporotic treatments.