sage

Salvia officinalis · Accepted scientific name

Scientific literature: Very Extensive (1705 studies) · ★★★★★

Sage, scientifically known as Salvia officinalis, is a perennial herb renowned for its aromatic leaves and therapeutic properties. Historically revered in traditional medicine, it offers potent antioxidant, anti-inflammatory, and antimicrobial benefits. Commonly used in culinary arts and herbal remedies, sage supports digestive health and cognitive function through its bioactive compounds.

Family
Lamiaceae
Native range
Europe
Parts used
Leaf · Seed
Common names
Garden Sage · Kitchen Sage · 4 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Salvia officinalis

Regional and Traditional Names

Spanish:

  • Salvia hortense menor
  • Te indígena
  • Salvia blancoana var. aurasiaca
  • Salvia lavandulifolia subsp approximata
  • Salvia real
  • Salvia de Moncayo
  • Salvia lavandulifolia var approximata
  • Salvia tenuior
  • Salvia menuda de España
  • Salvia oxyodon
  • Salvia hispanorum
  • Salvia lavandulifolia subsp. pyrenaeorum
  • Salvia lavandulifolia subsp pyrenaeorum
  • Salvia de granada
  • Salvia lavandulifolia var. lagascana
  • Salvia clusii
  • Te indigena
  • Mermasangre
  • Salvia
  • Salvia fina
  • Mermasangre
  • Salvia
  • Salvia Real
  • Salvia fina
  • Salvia dulce

German:

  • Echter Salbei
  • Garten-Salbei
  • Heilsalbei
  • Küchensalbei
  • Sauge Officinale
  • Salbei
  • Echter Salbei
  • Echte Salbei
  • Garten-Salbei
  • Heilsalbei
  • Küchensalbei

French:

  • sauge officinale
  • Thé d'europe
  • Sauge
  • Sauge officinale
  • sauge officinale
  • Sauge

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Lamiales and the family Lamiaceae, it is classified under the genus Salvia. Its specific scientific name is Salvia officinalis.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Lamiaceae
Genus Salvia

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific distribution pattern across several regions of the European continent. In Northern Europe, it can be found growing within the territories of Great Britain and Ireland. Moving toward the center of the continent, the species is also established in Middle Europe. Specifically, it inhabits parts of Austria as well as the regions of Czechia and Slovakia. Finally, its presence is well-documented throughout the country of Germany.

Region Area
Northern Europe Great Britain
Northern Europe Ireland
Middle Europe Austria
Middle Europe Czechia-Slovakia
Middle Europe Germany
Middle Europe Switzerland
Southwestern Europe Baleares
Southwestern Europe France
Southwestern Europe Portugal
Southwestern Europe Sardegna

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Salvia officinalis is characterized by its remarkable adaptability to a broad vertical gradient, spanning an elevational range from 0 m AMSL to a maximum of 2900 m AMSL. This wide altitudinal distribution allows the species to occupy diverse environmental niches, ranging from lowland coastal regions to high-altitude montane zones. Furthermore, the species frequently inhabits "Área Antrópica" (anthropic areas), demonstrating a high degree of tolerance to human-modified landscapes, including gardens, cultivated fields, and disturbed soils. This ability to thrive in both natural gradients and anthropogenic environments highlights its ecological plasticity and its capacity to persist in ecosystems shaped by human activity.

Elevational range max:
2900 m AMSL
Elevational range min:
0 m AMSL
Habitat :
Área Antrópica

Life history

The life history of Salvia officinalis is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons. Classified as a chamaephyte, its regenerative buds are located close to the soil surface, a life form that contributes to its resilience in various environments. Regarding its foliage, the species exhibits an evergreen nature, maintaining its leaves throughout much of the year rather than shedding them seasonally. This combination of a perennial lifecycle, a chamaephyte growth habit, and evergreen deciduousness defines its long-term survival strategy and physiological presence in its natural habitat.

Deciduousness :
evergreen
Life form :
chamaephyte
Lifecycle :
perennial

Morphology

The morphology of Salvia officinalis is characterized by a growth form that functions as both a shrub and a subshrub, exhibiting a non-woody structure. As a terrestrial plant, it is entirely independent, functioning as a non-parasitic organism rather than an epiphyte or a parasite. The plant is self-supporting in its growth habit, requiring no climbing mechanisms such as vines or lianas. In terms of vertical dimensions, it typically reaches a mean plant height of approximately 0.49 m, with individual specimens ranging from a minimum height of 0.25 m to a maximum height of 0.8 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
shrub
Growth form :
subshrub
Parasite :
independent
Plant height max:
0.8 m
Plant height mean:
0.491666666666667 m
Plant height min:
0.25 m
Woodiness :
non-woody

Physiology

The physiology of Salvia officinalis is characterized by a C3 photosynthetic pathway, utilizing standard carbon fixation processes common to many temperate medicinal herbs. The plant is non-carnivorous and does not function as a nitrogen fixer, relying instead on soil-based nutrient uptake. Its vegetative morphology is defined by oblong-shaped leaves that exhibit significant dimensional variation; leaf length typically ranges from a minimum of 2 cm to a maximum of 9 cm, while leaf width fluctuates between 0.8 cm and 3 cm, resulting in a mean leaf width of 1.5 cm. The average leaf size is measured at approximately 9.16833 cm², and the plant maintains a mean Specific Leaf Area (SLA) of 189.37 cm²/g, reflecting its structural efficiency and leaf density.

Carnivory :
non-carnivorous
Leaf form :
oblong
Leaf length max:
9 cm
Leaf length min:
2 cm
Leaf size mean:
9.16833 cm²
Leaf width max:
3 cm
Leaf width mean:
1.5 cm
Leaf width min:
0.8 cm
Nitrogen fixer :
no
Photosynthetic pathway :
C3
Specific Leaf Area (SLA) mean:
189.37 cm²/g

Reproduction

The reproduction of Salvia officinalis is driven by a biotic pollination syndrome, specifically relying on insects such as bees to facilitate fertilization. The plant exhibits a flowering period that typically begins in June and concludes in July, featuring violet-colored flowers that range in length from 1.5 cm to 2.5 cm. These flowers are arranged in inflorescences with a length varying between 0.1 m and 0.4 m. Notably, self-fertilization is absent in this species, and it does not utilize asexual reproduction. Following successful pollination, the plant produces fruit in the form of an achene. These fruits are indehiscent, with dimensions ranging from 0.2 cm to 0.3 cm in width. The resulting seeds are quite small, possessing a mean mass of 0.006035 g, with individual seed masses ranging from a minimum of 0.003 g to a maximum of 0.0086 g. Dispersal of the seeds is characterized by an unspecialized syndrome, though it also exhibits epizoochorous tendencies, allowing for spread via animals.

Dehiscence :
indehiscent
Dispersal syndrome :
unspecialized
Dispersal syndrome :
epizoochorous
Flower colour :
violet
Flower length max:
2.5 cm
Flower length min:
1.5 cm
Flowering time :
Jun
Flowering time :
Jul
Fruit type :
achene
Fruit width max:
0.3 cm
Fruit width min:
0.2 cm
Inflorescence length max:
0.4 m
Inflorescence length min:
0.1 m
Pollination syndrome :
insect
Pollination syndrome :
bee
Pollination syndrome :
biotic
Reproduction asexual :
absent
Seed mass max:
0.0086 g
Seed mass mean:
0.006035 g
Seed mass min:
0.003 g
Self fertilization :
absent

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Salvia officinalis has 2 reported plant parts identified across 9 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, seed.

Plant parts reported in Salvia officinalis
Plant part Supporting sources Consensus
Leaf 8 supporting sources ★★★★☆
Seed 1 supporting sources ★☆☆☆☆

Leaf

  1. Antioxidants (Basel, Switzerland)
  2. Journal of ethnopharmacology
  3. Neuroscience letters
  4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  5. Scientific reports
View 3 additional sources
  1. Applied biochemistry and biotechnology
  2. Biomedicines
  3. PloS one

Seed

  1. Chemistry & biodiversity

Chemicals

Salvia officinalis has 322 reported phytochemicals identified across 9 scientific publications and several other databases. The most consistently reported chemicals include rosmarinic acid, camphor, 1,8-Cineole, Flavonoids, carnosol.

Chemicals reported in Salvia officinalis
Chemical Supporting sources Consensus
rosmarinic acid 13 supporting sources ★★★★★
camphor 12 supporting sources ★★★★★
1,8-Cineole 10 supporting sources ★★★★★
Flavonoids 9 supporting sources ★★★★☆
carnosol 9 supporting sources ★★★★☆
Ursolic acid 8 supporting sources ★★★★☆
CAMPHENE 7 supporting sources ★★★★☆
cis-Thujone 7 supporting sources ★★★★☆
Carnosic acid 5 supporting sources ★★★☆☆
THUJONE 5 supporting sources ★★★☆☆

rosmarinic acid

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Journal of agricultural and food chemistry
  4. Experimental and therapeutic medicine
  5. Pharmaceuticals (Basel, Switzerland)
View 8 additional sources
  1. Food technology and biotechnology
  2. Phytochemistry
  3. Nutrition and cancer
  4. BMC plant biology
  5. Frontiers in plant science
  6. Plants (Basel, Switzerland)
  7. Planta
  8. Chemico-biological interactions

camphor

  1. Dr. Duke
  2. Plants (Basel, Switzerland)
  3. Frontiers in plant science
  4. Chemistry & biodiversity
  5. Journal of agriculture and food research
View 7 additional sources
  1. Pathogens (Basel, Switzerland)
  2. Journal of plant physiology
  3. Molecules (Basel, Switzerland)
  4. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
  5. Natural product research
  6. Natural product communications
  7. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

1,8-Cineole

  1. Dr. Duke
  2. Plants (Basel, Switzerland)
  3. Saudi journal of biological sciences
  4. Pathogens (Basel, Switzerland)
  5. Journal of plant physiology
View 5 additional sources
  1. Chemistry & biodiversity
  2. Natural product research
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  4. Scientific reports
  5. Frontiers in plant science

Flavonoids

  1. Insects
  2. Free radical biology & medicine
  3. Chemistry & biodiversity
  4. CNS & neurological disorders drug targets
  5. Planta medica
View 4 additional sources
  1. Food chemistry
  2. Current aging science
  3. Materials (Basel, Switzerland)
  4. Biomedicines

carnosol

  1. Dr. Duke
  2. Medical oncology (Northwood, London, England)
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Journal of ethnopharmacology
  5. Neuroscience letters
View 4 additional sources
  1. Plant & cell physiology
  2. Frontiers in immunology
  3. Journal of agricultural and food chemistry
  4. Planta

Ursolic acid

  1. Dr. Duke
  2. Zeitschrift fur Naturforschung. C, Journal of biosciences
  3. Scientific reports
  4. Heliyon
  5. Journal of natural products
View 3 additional sources
  1. Frontiers in immunology
  2. Journal of ethnopharmacology
  3. Phytochemistry

CAMPHENE

  1. Dr. Duke
  2. Saudi journal of biological sciences
  3. Pathogens (Basel, Switzerland)
  4. Molecules (Basel, Switzerland)
  5. Chemistry & biodiversity
View 2 additional sources
  1. Natural product communications
  2. Natural product research

cis-Thujone

  1. Plants (Basel, Switzerland)
  2. Saudi journal of biological sciences
  3. Pathogens (Basel, Switzerland)
  4. Chemistry & biodiversity
  5. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
View 2 additional sources
  1. Molecules (Basel, Switzerland)
  2. Natural product research

Carnosic acid

  1. Dr. Duke
  2. International journal of molecular sciences
  3. Neuroscience letters
  4. Plant & cell physiology
  5. Frontiers in plant science

THUJONE

  1. Dr. Duke
  2. Frontiers in plant science
  3. Bone
  4. Regulatory toxicology and pharmacology : RTP
  5. Ultrasonics sonochemistry

Activities

Salvia officinalis has 757 reported activities identified across 9 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Antimicrobial, Antidiabetic, Anticancer.

Activities reported in Salvia officinalis
Activity Supporting sources Consensus
Antioxidant 24 supporting sources ★★★★★
Antibacterial 12 supporting sources ★★★★★
Antimicrobial 10 supporting sources ★★★★★
Antidiabetic 7 supporting sources ★★★★☆
Anticancer 6 supporting sources ★★★☆☆
Antiinflammatory 3 supporting sources ★★☆☆☆
Antinociceptive 3 supporting sources ★★☆☆☆
Antiproliferative 3 supporting sources ★★☆☆☆
Antitumor 3 supporting sources ★★☆☆☆
Antiviral 3 supporting sources ★★☆☆☆

Antioxidant

  1. Dr. Duke
  2. Free radical biology & medicine
  3. Antioxidants (Basel, Switzerland)
  4. International journal of molecular sciences
  5. Molecules (Basel, Switzerland)
View 19 additional sources
  1. Neoplasma
  2. Planta medica
  3. Journal of ethnopharmacology
  4. Current pharmaceutical biotechnology
  5. Chemistry & biodiversity
  6. Archives of Razi Institute
  7. Journal of agriculture and food research
  8. Food research international (Ottawa, Ont.)
  9. Scientific reports
  10. Journal of plant physiology
  11. Natural product research
  12. Plants (Basel, Switzerland)
  13. Current aging science
  14. Advances in pharmacological and pharmaceutical sciences
  15. Combinatorial chemistry & high throughput screening
  16. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  17. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  18. Journal of the science of food and agriculture
  19. Journal of traditional and complementary medicine

Antibacterial

  1. Dr. Duke
  2. Scientific reports
  3. Molecules (Basel, Switzerland)
  4. Journal of ethnopharmacology
  5. Avicenna journal of phytomedicine
View 7 additional sources
  1. Chemistry & biodiversity
  2. Archives of Razi Institute
  3. Drug design, development and therapy
  4. Advances in pharmacological and pharmaceutical sciences
  5. Materials (Basel, Switzerland)
  6. Journal of agricultural and food chemistry
  7. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Antimicrobial

  1. Antioxidants (Basel, Switzerland)
  2. International journal of molecular sciences
  3. Molecules (Basel, Switzerland)
  4. Planta medica
  5. Current pharmaceutical biotechnology
View 5 additional sources
  1. Journal of plant physiology
  2. Letters in applied microbiology
  3. Plants (Basel, Switzerland)
  4. Revista de chirurgie, oncologie, radiologie, o. r. l., oftalmologie, stomatologie. Seria: Stomatologie
  5. Journal of traditional and complementary medicine

Antidiabetic

  1. Dr. Duke
  2. Antioxidants (Basel, Switzerland)
  3. Molecules (Basel, Switzerland)
  4. Journal of ethnopharmacology
  5. Journal of natural products
View 2 additional sources
  1. Advances in pharmacological and pharmaceutical sciences
  2. Iranian biomedical journal

Anticancer

  1. Dr. Duke
  2. Antioxidants (Basel, Switzerland)
  3. Medical oncology (Northwood, London, England)
  4. Planta medica
  5. Current pharmaceutical biotechnology
View 1 additional sources
  1. Journal of traditional and complementary medicine

Antiinflammatory

  1. Dr. Duke
  2. Stomatologiia
  3. Revista de chirurgie, oncologie, radiologie, o. r. l., oftalmologie, stomatologie. Seria: Stomatologie

Antinociceptive

  1. Dr. Duke
  2. Journal of ethnopharmacology
  3. Journal of traditional and complementary medicine

Antiproliferative

  1. Dr. Duke
  2. Natural product communications
  3. Nutrition and cancer

Antitumor

  1. Dr. Duke
  2. Plants (Basel, Switzerland)
  3. Combinatorial chemistry & high throughput screening

Antiviral

  1. Dr. Duke
  2. Journal of agriculture and food research
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Conditions

Salvia officinalis has 123 reported investigations on conditions identified across 9 scientific publications and several other databases. The most consistently reported conditions include oxidative stress, Alzheimer's disease, antioxidant, Escherichia coli, cancer.

Conditions investigated for Salvia officinalis
Condition Supporting sources Consensus
Oxidative stress 8 supporting sources ★★★★☆
Alzheimer's disease 7 supporting sources ★★★★☆
Antioxidant 7 supporting sources ★★★★☆
Escherichia coli 6 supporting sources ★★★☆☆
Cancer 6 supporting sources ★★★☆☆
Staphylococcus aureus 5 supporting sources ★★★☆☆
Inflammation 5 supporting sources ★★★☆☆
Antidiabetic 3 supporting sources ★★☆☆☆
Diabetes mellitus 3 supporting sources ★★☆☆☆
Hyperglycemia 3 supporting sources ★★☆☆☆

Oxidative stress

  1. Free radical biology & medicine
  2. Veterinary world
  3. Planta medica
  4. Scientific reports
  5. Journal of food biochemistry
View 3 additional sources
  1. Mutagenesis
  2. BMC plant biology
  3. Chemico-biological interactions

Alzheimer's disease

  1. Phytotherapy research : PTR
  2. British journal of pharmacology
  3. Metabolic brain disease
  4. Journal of clinical pharmacy and therapeutics
  5. Foods (Basel, Switzerland)
View 2 additional sources
  1. Heliyon
  2. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals

Antioxidant

  1. International journal of molecular sciences
  2. Journal of ethnopharmacology
  3. Current pharmaceutical biotechnology
  4. Journal of plant physiology
  5. Advances in pharmacological and pharmaceutical sciences
View 2 additional sources
  1. Plants (Basel, Switzerland)
  2. Journal of traditional and complementary medicine

Escherichia coli

  1. Veterinary medicine and science
  2. Experimental and therapeutic medicine
  3. Scientific reports
  4. Materials (Basel, Switzerland)
  5. Microorganisms
View 1 additional sources
  1. Pakistan journal of pharmaceutical sciences

Cancer

  1. Medical oncology (Northwood, London, England)
  2. Planta medica
  3. Zeitschrift fur Naturforschung. C, Journal of biosciences
  4. Journal of natural products
  5. Biomedicines
View 1 additional sources
  1. Asian Pacific journal of cancer prevention : APJCP

Staphylococcus aureus

  1. Scientific reports
  2. Experimental and therapeutic medicine
  3. General dentistry
  4. Materials (Basel, Switzerland)
  5. Microorganisms

Inflammation

  1. Free radical biology & medicine
  2. Planta medica
  3. Journal of medicinal food
  4. Journal of the science of food and agriculture
  5. Journal of traditional and complementary medicine

Antidiabetic

  1. Journal of ethnopharmacology
  2. Journal of natural products
  3. Advances in pharmacological and pharmaceutical sciences

Diabetes mellitus

  1. Veterinary world
  2. The Pan African medical journal
  3. Diabetes research (Edinburgh, Scotland)

Hyperglycemia

  1. Veterinary world
  2. Advances in pharmacological sciences
  3. Journal of traditional and complementary medicine

Preparations

Salvia officinalis has 67 reported preparations identified across 9 scientific publications and several other databases. The most consistently reported preparations include essential oils, Salvia officinalis extract, essential oil, extracts, methanolic extract.

Preparations reported for Salvia officinalis
Preparation Supporting sources Consensus
Essential oils 6 supporting sources ★★★☆☆
Salvia officinalis extract 4 supporting sources ★★☆☆☆
Essential oil 4 supporting sources ★★☆☆☆
Extracts 4 supporting sources ★★☆☆☆
Methanolic extract 3 supporting sources ★★☆☆☆
Methanolic extracts 3 supporting sources ★★☆☆☆
Aqueous extract 2 supporting sources ★☆☆☆☆
Ethanolic extract 2 supporting sources ★☆☆☆☆
Ethanolic extracts 2 supporting sources ★☆☆☆☆
66% ethanolic tincture 1 supporting sources ★☆☆☆☆

Essential oils

  1. Plants (Basel, Switzerland)
  2. Natural product research
  3. Acta poloniae pharmaceutica
  4. Molecules (Basel, Switzerland)
  5. Life sciences
View 1 additional sources
  1. Pakistan journal of pharmaceutical sciences

Salvia officinalis extract

  1. Scientific reports
  2. Journal of clinical pharmacy and therapeutics
  3. Journal of ethnopharmacology
  4. Biochimica et biophysica acta. General subjects

Essential oil

  1. Roczniki Panstwowego Zakladu Higieny
  2. Pathogens (Basel, Switzerland)
  3. Metabolites
  4. Planta

Extracts

  1. Frontiers in bioscience (Elite edition)
  2. Avicenna journal of phytomedicine
  3. Mutagenesis
  4. Dentistry journal

Methanolic extract

  1. Plants (Basel, Switzerland)
  2. Current aging science
  3. Chemico-biological interactions

Methanolic extracts

  1. Insects
  2. The Analyst
  3. BMC complementary medicine and therapies

Aqueous extract

  1. Plants (Basel, Switzerland)
  2. Applied biochemistry and biotechnology

Ethanolic extract

  1. Journal of ethnopharmacology
  2. Plants (Basel, Switzerland)

Ethanolic extracts

  1. Molecules (Basel, Switzerland)
  2. Letters in applied microbiology

66% ethanolic tincture

  1. Planta medica