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Updated: 1 20, 2025

Salvia miltiorrhiza

What is Salvia miltiorrhiza?

Salvia miltiorrhiza is a perennial plant that belongs to the family Lamiaceae.

Its botanical characteristics include ovate to lanceolate leaves that are 2-8 cm long and 1-4 cm wide, with a coarsely crenate margin and a petiole that is 1-3 cm long. The plant produces tall spikes of purple flowers, with a calyx that is 10-12 mm long and a corolla that is 18-22 mm long. The root of the plant contains phenolic glycosides, particularly tanshinones, which are responsible for its medicinal properties.

Salvia miltiorrhiza is native to China and is also known as Danshen.

What ailments can you heal with this herb?

The most common ailments you can heal with Salvia miltiorrhiza are hypertension, angina pectoris, and atherosclerosis, which Salvia miltiorrhiza has been shown to alleviate through its anti-inflammatory and antioxidant properties by reducing blood pressure and improving cardiovascular function.

Salvia miltiorrhiza also exhibits anti-diabetic properties, helping to regulate blood sugar levels in diabetic patients, and exhibits anti-arrhythmic properties, effectively treating cardiac arrhythmia by regulating heart rhythm. Additionally, Salvia miltiorrhiza has been found to prevent cardiovascular disease by improving blood flow and reducing inflammation, and has been shown to be effective in treating heart failure by improving cardiac function. Furthermore, Salvia miltiorrhiza has been used to treat varicose veins by improving blood circulation and reducing inflammation, and has been found to be effective in treating cardiomyopathy by improving heart muscle function.

Salvia miltiorrhiza has also been shown to be effective in treating a range of other conditions, including stroke, cardiac failure, Raynaud's disease, myocardial infarction, deep vein thrombosis, hyperlipidemia, cerebral infarction, coronary heart disease, cerebral ischemia, and chronic kidney disease.

What are the therapeutic properties this herb?

The main therapeutic properties of Salvia miltiorrhiza are rooted in its antioxidant activity, which helps protect against oxidative stress and cellular damage.

The anti-inflammatory properties of this plant are also significant, as they can help alleviate symptoms associated with conditions such as arthritis and other inflammatory diseases. Salvia miltiorrhiza has cardioprotective effects, particularly in the context of cardiovascular diseases, where it can help improve blood flow and reduce the risk of heart failure. Additionally, this plant exhibits neuroprotective properties, which may be beneficial in the treatment of neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease.

Its antimicrobial properties make it useful in the treatment of bacterial and fungal infections, where it can help inhibit the growth of pathogens and promote healing.

What are the medicinal constituents this herb?

The most important healing constituents of Salvia miltiorrhiza are tanshinone I and its derivatives, such as tanshinone IIA methyl ester, and cryptotanshinone, which have been shown to have anti-inflammatory, anti-arrhythmic, and antioxidant effects by reducing oxidative stress and improving cardiovascular function.

Additionally, rosmarinic acid, a phenolic diterpene, and salvianolic acid B, a water-soluble phenolic acid, possess antioxidant and anti-inflammatory properties, which contribute to the cardiovascular protective effects of Salvia miltiorrhiza. Tanshinone IIA methyl ester has been found to increase the expression of vascular endothelial growth factor, promoting angiogenesis and improving cardiovascular function. Salvianolic acid B has been shown to scavenge free radicals and reduce lipid peroxidation, further contributing to the antioxidant effects of Salvia miltiorrhiza.

The combination of these constituents in Salvia miltiorrhiza has been found to have a synergistic effect, enhancing its overall cardiovascular protective and therapeutic effects.

What are the main herbal preparations this herb?

The main herbal preparations of Salvia miltiorrhiza are salvia injection, salvia tincture, salvia tea, salvia extract, and salvia decoction.

Salvia injection is a liquid solution used to treat cardiovascular diseases, including angina and myocardial infarction, due to its high content of active compounds such as salvianolic acid A and tanshinone IIA. Salvia tincture is a concentrated liquid extract used to treat various conditions, including cardiovascular disease, fever, and inflammation, due to its bioactive compounds like salvianolic acid A and tanshinone IIA. Salvia tea is a traditional preparation made by infusing dried Salvia miltiorrhiza roots in hot water, used to treat conditions like cardiovascular disease, fever, and inflammation, due to its bioactive compounds like salvianolic acid A and tanshinone IIA.

Salvia extract and salvia decoction are other preparations made by extracting bioactive compounds from Salvia miltiorrhiza roots, used to treat various conditions, including cardiovascular disease, fever, and inflammation.

What are the possible side effects of using this herb improperly?

The possible side effects of using Salvia miltiorrhiza improperly include an increased risk of bleeding due to its ability to inhibit platelet aggregation and decrease clotting factor activity.

This is because Salvia miltiorrhiza contains salvianolic acid B which has anticoagulant properties that can increase the risk of bleeding when combined with anticoagulant medications. Additionally, Salvia miltiorrhiza can induce seizures in some individuals due to its potential to lower the seizure threshold and interact with medications such as antidepressants and antihypertensives. It can also exacerbate hypertension and trigger hypotension as it may cause vasodilation and lower blood pressure, particularly when combined with other blood pressure-lowering medications.

Furthermore, Salvia miltiorrhiza can cause hallucinations due to its effect on the central nervous system, particularly the dopaminergic and serotonergic systems, leading to altered perception and cognitive function.