Diviner's Sage

Salvia divinorum · Accepted scientific name

Scientific literature: Sparse (77 studies) · ★★☆☆☆

Divineer's Sage, scientifically known as Salvia divinorum, is a perennial herb celebrated for its striking, velvety leaves and aromatic qualities. Often revered in traditional practices, this plant belongs to the mint family. It is frequently studied for its unique bioactive compounds and its significant role in various botanical traditions.

Family
Lamiaceae
Native range
Northern America
Parts used
Leaf
Common names
Divining Sage · Herb-Of-The-Virgin · 4 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Salvia divinorum

Regional and Traditional Names

Spanish:

  • S divinorum
  • Ska Maria
  • S. divinorum
  • Ska María
  • Ska pastora
  • Ojos de la Pastora
  • hierba de María
  • hoja de la pastora
  • Hierba de la Virgen
  • hierba de la pastora
  • ska pastora

German:

  • Azteken-Salbei
  • Aztekensalbei
  • Wahrsagesalbei
  • Wahrsage-Salbei
  • Göttersalbei
  • Pipiltzitzintl
  • Zaubersalbei
  • Azteken-Salbei

French:

  • Sauge des devins
  • Salvia divinorium
  • Sauge des devins

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, Salvia divinorum, belongs to the kingdom Plantae within the phylum Streptophyta and the class Equisetopsida. It is further classified under the subclass Magnoliidae and the order Lamiales, falling into the family Lamiaceae. Ultimately, its taxonomic identity is defined by its placement within the genus Salvia.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Lamiaceae
Genus Salvia

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, known as Salvia divinoorum, possesses a very specific and limited natural range. Its primary geographical distribution is centered within the nation of Mexico. More specifically, the species is found inhabiting the various landscapes of Southwest Mexico. Because of this localized presence, it is considered an endemic species to that particular region. Consequently, researchers looking for this medicinal plant must focus their efforts on the southwestern territories of the country.

Region Area
Mexico Mexico Southwest

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Morphology

The morphology of Salvia divinorum is characterized by a decumbent to ascending growth habit, where the stems are distinctly non-woody, maintaining a herbaceous and succulent texture throughout their development. The plant typically features long, square-shaped stems that are quadrangular in cross-section, a common trait among the Lamiaceae family, and they often exhibit a light green to purplish coloration. The leaves are large, opposite, and ovate to oblong in shape, possessing a rugose or wrinkled surface texture with serrated margins and prominent venation. These leaves are arranged in decussate pairs along the flexible, non-woody stems. The inflorescence is composed of verticillasters, which are whorl-like clusters of flowers situated in the axils of the upper leaves, typically presenting small, tubular, two-lipped flowers that vary in color from white to pale blue or purple. The overall architecture of the plant is lush and spreading, relying on its herbaceous, non-woody structure to expand across its habitat.

Woodiness :
non-woody

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Salvia divinorum has 1 reported plant parts identified across 7 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf.

Plant parts reported in Salvia divinorum
Plant part Supporting sources Consensus
Leaf 7 supporting sources ★★★★☆

Leaf

  1. Synapse (New York, N.Y.)
  2. Forensic science international
  3. Journal of psychoactive drugs
  4. Bioorganic & medicinal chemistry letters
  5. Organic letters
View 2 additional sources
  1. Journal of ethnopharmacology
  2. Journal of natural products

Chemicals

Salvia divinorum has 13 reported phytochemicals identified across 7 scientific publications and several other databases. The most consistently reported chemicals include Salvinorin A, Divinorin A, (-)-Hardwickiic acid, (-)-Kolavenol, (-)-kolavenyl diphosphate.

Chemicals reported in Salvia divinorum
Chemical Supporting sources Consensus
Salvinorin A 20 supporting sources ★★★★★
Divinorin A 2 supporting sources ★☆☆☆☆
(-)-Hardwickiic acid 1 supporting sources ★☆☆☆☆
(-)-Kolavenol 1 supporting sources ★☆☆☆☆
(-)-kolavenyl diphosphate 1 supporting sources ★☆☆☆☆
Hallucinogen 1 supporting sources ★☆☆☆☆
Salvidivin C 1 supporting sources ★☆☆☆☆
Salvidivin D 1 supporting sources ★☆☆☆☆
Salvinorin 1 supporting sources ★☆☆☆☆
Salvinorin B 1 supporting sources ★☆☆☆☆

Salvinorin A

  1. Synapse (New York, N.Y.)
  2. Forensic science international
  3. BMC plant biology
  4. Journal of natural medicines
  5. Planta medica
View 15 additional sources
  1. Human psychopharmacology
  2. Journal of medicinal chemistry
  3. European journal of medicinal chemistry
  4. Journal of psychoactive drugs
  5. Life sciences
  6. Frontiers in pharmacology
  7. European journal of pain (London, England)
  8. Journal of psychopharmacology (Oxford, England)
  9. Bioorganic & medicinal chemistry letters
  10. Pharmacological research
  11. Journal of experimental botany
  12. The international journal of neuropsychopharmacology
  13. Journal of ethnopharmacology
  14. Journal of natural products
  15. Advances in pharmacology (San Diego, Calif.)

Divinorin A

  1. Forensic science international
  2. Journal of psychoactive drugs

(-)-Hardwickiic acid

  1. Journal of natural products

(-)-Kolavenol

  1. Journal of experimental botany

(-)-kolavenyl diphosphate

  1. Journal of experimental botany

Hallucinogen

  1. Life sciences

Salvidivin C

  1. Journal of natural products

Salvidivin D

  1. Journal of natural products

Salvinorin

  1. Dr. Duke

Salvinorin B

  1. European journal of pain (London, England)

Activities

Salvia divinorum has 6 reported activities identified across 7 scientific publications and several other databases. The most consistently reported activities include Hallucinogen, Hallucinogenic, Psychoactive, Analgesic, Antinociceptive.

Activities reported in Salvia divinorum
Activity Supporting sources Consensus
Hallucinogen 6 supporting sources ★★★☆☆
Hallucinogenic 6 supporting sources ★★★☆☆
Psychoactive 5 supporting sources ★★★☆☆
Analgesic 1 supporting sources ★☆☆☆☆
Antinociceptive 1 supporting sources ★☆☆☆☆
Psychotropic 1 supporting sources ★☆☆☆☆

Hallucinogen

  1. Synapse (New York, N.Y.)
  2. BMC plant biology
  3. Journal of psychoactive drugs
  4. Life sciences
  5. Frontiers in pharmacology
View 1 additional sources
  1. Bioorganic & medicinal chemistry letters

Hallucinogenic

  1. Journal of natural products
  2. Forensic science international
  3. Human psychopharmacology
  4. Journal of medicinal chemistry
  5. Journal of ethnopharmacology
View 1 additional sources
  1. Journal of plant research

Psychoactive

  1. Neurologia (Barcelona, Spain)
  2. European journal of medicinal chemistry
  3. The international journal of neuropsychopharmacology
  4. Journal of ethnopharmacology
  5. Journal of natural products

Analgesic

  1. Journal of ethnopharmacology

Antinociceptive

  1. European journal of pain (London, England)

Psychotropic

  1. Journal of ethnopharmacology

Conditions

Salvia divinorum has 8 reported investigations on conditions identified across 7 scientific publications and several other databases. The most consistently reported conditions include neuropathic pain, chronic pain, epilepsy, epileptic seizures, nociceptive pain.

Conditions investigated for Salvia divinorum
Condition Supporting sources Consensus
Neuropathic pain 2 supporting sources ★☆☆☆☆
Chronic pain 1 supporting sources ★☆☆☆☆
Epilepsy 1 supporting sources ★☆☆☆☆
Epileptic seizures 1 supporting sources ★☆☆☆☆
Nociceptive pain 1 supporting sources ★☆☆☆☆
Pain 1 supporting sources ★☆☆☆☆
Post-traumatic stress disorder 1 supporting sources ★☆☆☆☆
Status epilepticus 1 supporting sources ★☆☆☆☆

Neuropathic pain

  1. Journal of ethnopharmacology
  2. European journal of pain (London, England)

Chronic pain

  1. BMC plant biology

Epilepsy

  1. Journal of ethnopharmacology

Epileptic seizures

  1. Journal of ethnopharmacology

Nociceptive pain

  1. Journal of ethnopharmacology

Pain

  1. Journal of ethnopharmacology

Post-traumatic stress disorder

  1. BMC plant biology

Status epilepticus

  1. Journal of ethnopharmacology

Preparations

Salvia divinorum has 16 reported preparations identified across 7 scientific publications and several other databases. The most consistently reported preparations include "magic mint", SD extract, Salvinorin A (Sal A), aqueous infusion, chewing the fresh leaves.

Preparations reported for Salvia divinorum
Preparation Supporting sources Consensus
"magic mint" 1 supporting sources ★☆☆☆☆
Sd extract 1 supporting sources ★☆☆☆☆
Salvinorin a (sal a) 1 supporting sources ★☆☆☆☆
Aqueous infusion 1 supporting sources ★☆☆☆☆
Chewing the fresh leaves 1 supporting sources ★☆☆☆☆
Dried leaves 1 supporting sources ★☆☆☆☆
Drinking the juices of freshly crushed leaves 1 supporting sources ★☆☆☆☆
Eaten raw 1 supporting sources ★☆☆☆☆
Ethyl acetate 1 supporting sources ★☆☆☆☆
Ethyl acetate extract (eaex) 1 supporting sources ★☆☆☆☆

"magic mint"

  1. Life sciences

Sd extract

  1. Journal of ethnopharmacology

Salvinorin a (sal a)

  1. Advances in pharmacology (San Diego, Calif.)

Aqueous infusion

  1. Journal of psychoactive drugs

Chewing the fresh leaves

  1. Journal of ethnopharmacology

Dried leaves

  1. Organic letters

Drinking the juices of freshly crushed leaves

  1. Journal of ethnopharmacology

Eaten raw

  1. Journal of psychoactive drugs

Ethyl acetate

  1. Journal of ethnopharmacology

Ethyl acetate extract (eaex)

  1. Journal of ethnopharmacology