Rubus chingii

What's the taxonomical classification of Rubus chingii?

Rubus chingii belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Following the order Rosales, the plant is a member of the family Rosaceae. It is further defined by its genus, Rubus, and is specifically identified by its species name, chingii.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Rosales
Family Rosaceae
Genus Rubus
Species chingii
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Rubus chingii has a woody, perennial growth habit characterized by arching canes that are densely covered in small, sharp prickles. The leaves are typically compound with three to five leaflets that feature serrated margins and a somewhat rugose texture. Small, fragrant white flowers emerge from the terminal ends of the branches during the blooming season. These blossoms eventually develop into aggregate drupelets that mature into fleshy, dark red or purple berries. The plant's root system is robust, allowing it to establish itself firmly in forest understories or disturbed soils.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the mountainous regions of central and southern China, specifically within provinces such as Hubei, Hunan, and Sichuan. It typically thrives in high-altitude habitats characterized by cool, moist climates and shaded forest environments. These botanical specimens are often found growing along the edges of woodlands or on rocky slopes where drainage is sufficient. The species is not widely distributed across other continents, remaining largely concentrated within its specific East Asian ecological niche. Its presence is closely tied to the unique soil compositions and temperature gradients found in these temperate montane zones.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Rubus chingii requires well-drained, fertile soil and a temperate climate with moderate sunlight to thrive during its growth cycle.

Growers typically propagate the species through stem cuttings or layering to ensure consistent genetic traits. Regular irrigation is essential, especially during the establishment phase, to prevent root desiccation in sandy substrates. Maintaining a balanced pH level helps optimize the development of its medicinal berries.

Careful pruning is also necessary to manage the sprawling canes and encourage productive yields.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant uses the fruit and berries of Rubus chingii as its primary medicinal components for treating various ailments. The dark berries, which are the same as the fruit, contain high levels of antioxidants and are often processed into traditional remedies. While the berries are the main focus, some preparations may incorporate the flowers to enhance the herbal formula. The leaves are occasionally utilized in decoctions to provide additional therapeutic properties. Even the stem can be integrated into specific medicinal mixtures depending on the intended health benefit.

According to a study published by "Frontiers in plant science", Rubus chingii Hu is a berry plant that possesses high nutritional and medicinal value. This plant is rich in flavonoids, including flavonols and proanthocyanidins. Researchers identified two FLS genes, RcFLS1 and RcFLS2, and one DFR gene, RcDFR, from the species. These genes were found to be highly expressed in the stems, leaves, and flowers of the plant. In these specific organs, the accumulation of flavonols was significantly higher than that of proanthocyanidins.

The parts of this plant that are ued medicinally are shown in the list below.

  • berry
  • flowers
  • leaves
  • stem
  • fruit
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, Rubus chingii, has been utilized in Traditional Chinese Medicine for centuries to treat conditions related to kidney deficiency and to promote sexual vitality. Practitioners historically prescribed the berries and roots to nourish the essence and strengthen the lower burner of the body. It was frequently used in herbal formulas to address symptoms such as dizziness, low back pain, and fatigue. Beyond its role in reproductive health, historical applications also included managing urinary issues and inflammation. These long-standing medicinal practices emphasize the plant's ability to balance internal energies according to ancient healing principles.

According to a study published by "International journal of oncology", Rubus chingii Hu is one of 9 herbs used in the Equiguard dietary supplement. The formulation of this product follows Chinese traditional medicinal concepts. It is aimed at restoring harmony in the primordial yin-yang of the kidney. This organ is considered vital for invigorating and maintaining the balance of the entire urological system.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Chinese Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Rubus chingii?

This plant has anti-inflammatory, anti-oxidant, anti-tumor, immunomodulatory, and renoprotective pharmacological activities. Its diverse biological properties stem from a rich profile of bioactive compounds such as ellagitannins and various phenolic acids. These constituents work together to neutralize free radicals and reduce oxidative stress throughout the body. The plant also demonstrates the ability to regulate immune responses and inhibit the uncontrolled growth of certain cancer cells. Furthermore, its protective effects extend to the renal system, helping to mitigate damage to kidney tissues.

According to a study published by "Frontiers in nutrition", Rubus chingii Hu, also known as Fu-Pen-Zi, is a woody perennial plant of the genus Rubus in the Rosaceae family. This food-medicine herb has been used in China for thousands of years to treat diseases such as impotence, premature ejaculation, enuresis, and frequent urination. The bioactive components within the plant mainly include terpenoids, flavonoids, alkaloids, phenolic acids, polysaccharides, and steroids. Its main pharmacological effects on human health consist of anti-oxidant, anti-inflammatory, and anti-tumor capacity. Although it is a very valuable herb, the development of related drugs is relatively single and limited to traditional Chinese medicine and prescriptions.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • anti-oxidant
  • anti-tumor
  • immunomodulatory
  • renoprotective
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains several bioactive medicinal compounds including ursolic acid, oleanolic acid, ellagic acid, kaempferol, and maslinic acid. These specific triterpenoids and polyphenols contribute to the plant's diverse pharmacological activities. Research suggests that these substances provide significant antioxidant and anti-inflammatory benefits to the human body. The presence of these chemical constituents makes the plant a subject of interest for developing new therapeutic agents. Scientists continue to study how these individual compounds interact to promote overall health.

According to a study published by "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", eleven compounds were isolated and purified from the fruit of Rubus chingii using recrystallization and chromatography with silica gel column and Sephadex LH-20 column. These isolated compounds include oleanic acid (I), ursolic acid (II), maslinic acid (III), 2alpha-hydroxyursolic acid (IV), arjunic acid (V), hexacosyl p-coumarate (VI), tiliroside (VII), stearic acid (VIII), lacceroic acid (IX), beta-sitosterol (X), and daucosterol (XI). The structures of these compounds were identified through spectral analysis and physicochemical properties. Compounds I, II, III, IV, V, VI, VIII, IX, and XI were isolated from Rubus chingii for the first time.

The primary medicinal compounds of this plant are shown in the list below.

  • ellagic acid
  • ursolic acid
  • oleanolic acid
  • kaempferol
  • quercetin
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating impaired renal function, kidney-related ailments, impotence, premature ejaculation, and frequent urination. Its medicinal properties are traditionally applied to support the urinary system and enhance reproductive health in men. By addressing kidney-related ailments, it helps stabilize bladder control and reduce the need for frequent urination. Furthermore, it is frequently utilized in herbal remedies to manage sexual dysfunction such as impotence and premature ejaculation. These diverse applications make it a significant component in traditional treatments for both renal and male vitality issues.

According to a study published by "Journal of pharmaceuctical and biomedical analysis", Rubus chingii Hu is used as a traditional Chinese medicine to nourish kidney and strengthen Yang-qi. The plant is used to improve renal function through the action of six components including rutin, ellagic acid, kaempferol-3-rutinoside, astragalin, tiliroside, and goshonoside F5. These components can markedly inhibit cell damage induced by cisplatin in HEK293 cells. The components also work to restore the levels of malondialdehyde (MDA) and catalase (CAT) in the cells. Five of these quality markers were found to be higher in raspberries from Dexing of Jiangxi province compared to most other areas.

The main health conditions this plant is used for are shown in the list below.

  • impaired renal function
  • kidney-related ailments
  • impotence
  • premature ejaculation
  • renal fibrosis
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is processed into medicinal herbal preparations including aqueous extracts and ethanol extracts to harness its bioactive compounds. Aqueous extracts are commonly prepared by boiling the plant material in water to isolate water-soluble constituents. Ethanol extracts utilize alcohol as a solvent to target lipophilic components that water cannot effectively dissolve. These different preparation methods allow for the specific extraction of various phytochemicals used in traditional and modern pharmacology. Researchers study these distinct preparations to determine their individual therapeutic effects on human health.

According to a study published by "Life sciences", aqueous extracts of Rubus chingii fruits were found to be the most potent of the five herbal components of Wu-zi-yan-zong-wan. In investigations using a primary rat hepatocyte system, pre-treatment with Fructus Rubi extract at concentrations ranging from 50 microg/ml to 200 microg/ml for 24 h significantly reversed cell damage. This treatment reversed tert-butyl hydroperoxide induced cell viability loss, lactate dehydrogenase leakage, glutathione depletion, and lipid peroxidation. The amount of reactive oxygen species formed was also decreased as visualized by the fluorescence probe 2',7'-dichlorofluorescin diacetate. These results suggest that Rubus chingii is useful in protecting against oxidative damage and may attenuate the cytotoxicity of other oxidants.

The main herbal preparations of this plant are shown in the list below.

  • aqueous extract
  • ethanol extracts
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can exhibit various pharmacological properties rather than health side effects when consumed. It is primarily recognized for its ability to help regulate blood sugar levels and improve metabolic functions. The plant also demonstrates significant antioxidant activities that may protect cells from oxidative stress. Additionally, certain studies suggest it possesses anti-inflammatory characteristics that support overall wellness. These biological actions represent the therapeutic potential of the plant instead of negative reactions.

The main side effects this plant can have are shown in the list below.

  • None of the items listed are side effects; they are pharmacological properties.
Evidence Level: ★★★☆☆

What herbs are paired with Rubus chingii?

This plant is most commonly paired with herbs such as Rehmannia glutinosa, Cornus officinalis, and Dioscorea opposita to enhance its ability to nourish kidney yin and blood.

These combinations are frequently used in traditional formulas to address deficiencies in the essence and liver functions. Adding Schisandra chinensis can further strengthen the astringent properties of the berry to prevent the leakage of fluids. Practitioners often select these specific adjuncts to balance the cooling nature of the plant during long-term tonic therapy.

This synergistic approach ensures that the medicinal effects are targeted toward restorative vitality.

Evidence Level: ★☆☆☆☆