African serpentwood

Rauvolfia vomitoria · Accepted scientific name

Scientific literature: Extensive (154 studies) · ★★★★☆

African serpentwood, scientifically known as Rauvolfia vomitoria, is a medicinal shrub native to tropical Africa. Renowned for its potent alkaloids, particularly reserpine, it has been used traditionally to treat hypertension and mental disorders. This plant serves as a vital botanical resource in both ethnobotany and modern pharmacology.

Family
Apocynaceae
Native range
Africa
Parts used
Leaf · Root
Common names
African Serpentwood · African Snakeroot · 3 more
Scientific synonyms
Rauvolfia Senegambiae · Rauvolfia Pleiosiadica · 2 more

Names

Common Names

Regional and Traditional Names

German:

  • Brech-Teufelspfeffer

Scientific Names

Accepted name

Rauvolfia vomitoria

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Gentianales, it is classified under the family Apocynaceae. Ultimately, its taxonomic identity is defined by the genus Rauvolfia.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Gentianales WCVP
Family Apocynaceae WCVP
Genus Rauvolfia WCVP

Distribution

This plant is primarily distributed across the region of West Tropical Africa. Within this specific zone, its presence is documented in the nation of Benin. It is also found inhabiting the landscapes of Burkina. Furthermore, the species can be located throughout Ghana and Guinea-Bissau. Finally, its geographical range extends into the country of Guinea.

Region Area Source
West Tropical Africa Benin WCVP
West Tropical Africa Burkina WCVP
West Tropical Africa Ghana WCVP
West Tropical Africa Guinea-Bissau WCVP
West Tropical Africa Guinea WCVP
West Tropical Africa Ivory Coast WCVP
West Tropical Africa Liberia WCVP
West Tropical Africa Mali WCVP
West Tropical Africa Nigeria WCVP
West Tropical Africa Senegal WCVP

Plant Parts

This plant, Rauvolfia vomitoria, is highly valued in traditional medicine, with various components serving specific therapeutic purposes. The foliage and individual leaf structures are often studied for their chemical properties, though the most potent medicinal compounds are concentrated underground. Specifically, the roots contain high concentrations of alkaloids, and the root bark is frequently harvested for its pharmacological potency. Whether utilizing the raw root barks or processed extracts, each part contributes to the plant's significant role in treating various ailments.
Plant Part Sources Consensus
leaf Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria (and other 2 sources) ★☆☆☆☆
root Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Chemicals

Rauvolfia vomitoria has 35 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include Ajmalicine, Flavonoids, Yohimbine, ajmaline, reserpine.

Chemicals reported in Rauvolfia vomitoria
Chemical Supporting sources Consensus
Ajmalicine 2 supporting sources ★☆☆☆☆
Flavonoids 2 supporting sources ★☆☆☆☆
Yohimbine 2 supporting sources ★☆☆☆☆
ajmaline 2 supporting sources ★☆☆☆☆
reserpine 2 supporting sources ★☆☆☆☆
ALSTONINE 1 supporting sources ★☆☆☆☆
Anthocyanins 1 supporting sources ★☆☆☆☆
Aricine 1 supporting sources ★☆☆☆☆
Carapanaubine 1 supporting sources ★☆☆☆☆
ISOAJMALINE 1 supporting sources ★☆☆☆☆

Ajmalicine

  1. Dr. Duke
  2. Journal of separation science

Flavonoids

  1. Evidence-based complementary and alternative medicine : eCAM
  2. Journal of basic and clinical physiology and pharmacology

Yohimbine

  1. Dr. Duke
  2. Journal of separation science

ajmaline

  1. Dr. Duke
  2. Journal of separation science

reserpine

  1. Dr. Duke
  2. Journal of separation science

ALSTONINE

  1. Dr. Duke

Anthocyanins

  1. Evidence-based complementary and alternative medicine : eCAM

Aricine

  1. Dr. Duke

Carapanaubine

  1. Dr. Duke

ISOAJMALINE

  1. Dr. Duke

Activities

Rauvolfia vomitoria has 100 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Anticonvulsant, Antiinflammatory, Antioxidant, (-)-Chronotropic, Abortifacient.

Most Reported Activities

Activity Sources Consensus
Anticonvulsant Dr. Duke (and other 2 sources) ★☆☆☆☆
Antiinflammatory Dr. Duke (and other 2 sources) ★☆☆☆☆
Antioxidant Dr. Duke (and other 2 sources) ★☆☆☆☆
(-)-Chronotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
Abortifacient Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenergic-Blocker Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenolytic Dr. Duke (and other 1 sources) ★☆☆☆☆
Allergenic Dr. Duke (and other 1 sources) ★☆☆☆☆
Amebicide Dr. Duke (and other 1 sources) ★☆☆☆☆
Anesthetic Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Rauvolfia vomitoria has 4 reported medicinal uses identified across 3 scientific publications and several other databases. The most consistently reported uses include diabetes mellitus, malaria, psychosis, rheumatoid arthritis.

Most Reported Uses

Use Sources Consensus
diabetes mellitus Journal of separation science (and other 1 sources) ★☆☆☆☆
malaria Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
psychosis Journal of basic and clinical physiology and pharmacology (and other 1 sources) ★☆☆☆☆
rheumatoid arthritis Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
Asofeyeje (Root) Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Ghanaian antiarthritic herbal preparation Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
aqueous and hydroethanolic extracts Evidence-based complementary and alternative medicine : eCAM (and other 1 sources) ★☆☆☆☆
encapsulated in alginate beads Natural product communications (and other 1 sources) ★☆☆☆☆
tea Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆