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Updated: Jul 21, 2024

10 Possible Side Effects Of Punica Granatum (Pomegranate)

punica granatum

Punica granatum has some side effects when used improperly, such as allergic reactions, digestive problems, and interactions with medications.

The causes of these side effects include overconsumption, individual sensitivities, and concurrent use with certain medications. For example, an allergic reaction can worsen a person's life by causing anaphylaxis, a potentially life-threatening condition.

Additionally, digestive problems can lead to chronic discomfort, weight loss, and nutrient deficiencies.

This article explains in details the 10 most common side effects of Punica granatum if used imporperly.

1. Produces stomach ulcers

Punica granatum causes allergic reactions in some individuals.

This is often due to the presence of specific allergenic compounds such as punicalagins and ellagic acid, which are naturally found in the fruit's juice, seeds, and rind. Additionally, the pollen of the pomegranate tree can also trigger allergies in sensitive people.

These allergens can cause symptoms ranging from mild skin irritation to more severe reactions such as hives, itching, and difficulty breathing.

2. Produces stomach ulcers

Punica granatum triggers asthma attacks due to its potential allergenic properties and ability to cause inflammation in the airways.

The fruit's juice and extracts contain compounds that can stimulate an allergic response, leading to constriction of the airways and increased mucus production.

Additionally, Punica granatum may exacerbate pre-existing respiratory conditions, causing wheezing, shortness of breath, and coughing fits in individuals with asthma.

3. Produces stomach ulcers

Punica granatum induces kidney damage due to its high content of oxalates and potassium, which can exacerbate existing kidney issues.

The excess oxalic acid in pomegranate may bind to calcium in the kidneys, forming insoluble compounds that increase the risk of kidney stone formation and potentially damage the kidneys' filtering ability.

Additionally, the high potassium levels in pomegranate can cause an imbalance in electrolytes, leading to further kidney strain.

4. Produces stomach ulcers

Punica granatum increases blood pressure due to its high levels of polyphenols and flavonoids.

These compounds can cause blood vessels to constrict, leading to an increase in blood pressure.

Additionally, the potassium content in Punica granatum may also contribute to this effect by counteracting the natural effects of potassium-lowering medications, further increasing blood pressure.

5. Produces stomach ulcers

Punica granatum disrupts thyroid function due to its potential to interact with thyroid hormones.

The fruit's high polyphenol content can bind to and inhibit the absorption of iodine, a crucial nutrient for thyroid gland functioning. Additionally, Punica granatum may contain goitrin, a compound that inhibits the production of thyroxine (T4) and triiodothyronine (T3), two essential hormones produced by the thyroid gland.

As a result, regular consumption of Punica granatum may lead to altered thyroid function and potentially impact overall health.

6. Produces stomach ulcers

Punica granatum interacts with medications, potentially causing adverse effects.

This is due to its high content of ellagic acid and punicalagins, which can inhibit the activity of certain enzymes involved in drug metabolism, leading to increased levels of medication in the bloodstream.

Additionally, pomegranate's antioxidant properties may enhance the activity of certain medications, amplifying their therapeutic effects or side effects.

7. Produces stomach ulcers

Punica granatum stimulates digestive issues due to its high tannin content and potential allergenic properties.

The tannins in pomegranate may cause stomach upset, diarrhea, or nausea by altering the balance of gut bacteria and reducing nutrient absorption.

Additionally, some individuals may be allergic to specific compounds in pomegranate, leading to gastrointestinal symptoms such as bloating and cramping.

8. Produces stomach ulcers

Punica granatum lowers platelet count due to its potential interference with blood clotting processes.

The anthocyanins and ellagic acid present in pomegranate may inhibit platelet activation and aggregation, leading to decreased platelet counts. Additionally, the flavonoids and polyphenols found in pomegranate may also contribute to this effect by affecting the body's ability to form blood clots.

As a result, individuals taking pomegranate supplements or consuming large amounts of pomegranate juice may experience a decrease in their platelet count.

9. Produces stomach ulcers

Punica granatum increases liver enzymes when used.

This is due to the high antioxidant and polyphenol content of pomegranate, which can cause an increased breakdown of fat in the liver, leading to elevated liver enzyme levels.

Additionally, the anthocyanins present in pomegranate may interact with certain medications, such as blood thinners, and increase their potency, further contributing to this side effect.

10. Produces stomach ulcers

Punica granatum causes nausea and vomiting due to its high concentration of tannins, which can irritate the stomach lining and disrupt digestion.

The astringent properties of pomegranate may also contribute to this side effect by drawing out fluids from the digestive tract, leading to dehydration and discomfort.

Additionally, some people may be allergic to pomegranate or have sensitivities that trigger an adverse reaction in the body, resulting in nausea and vomiting.