Fallopia multiflora
Pleuropterus multiflorus · Accepted scientific name
Scientific literature: Very Extensive (760 studies) · ★★★★★
Fallopia multiflora, scientifically known as Pleuropterus multiflorus, is a perennial herb native to East Asia, highly revered in traditional medicine. Commonly called Japanese knotweed, its nutrient-rich rhizomes contain potent compounds like resveratrol, offering significant antioxidant and anti-inflammatory benefits used to support circulation, longevity, and overall metabolic health.
- Family
- Polygonaceae
- Native range
- Asia-Temperate
- Parts used
- Root · Leaf
- Common names
- Not available
- Scientific synonyms
- Reynoutria Multiflora · Fallopia Multiflora · 10 more
Names and Synonyms
Scientific Names
Accepted name
Pleuropterus multiflorusSynonyms
- Reynoutria multiflora
- Fallopia multiflora
- Helxine multiflorum
- Pleuropterus cordatus
- Fallopia multiflora var. hypoleuca
- Bilderdykia multiflora
- Aconogonon hypoleucum
- Reynoutria multiflora var. hypoleuca
- Fagopyrum multiflorum
- Polygonum multiflorum var. hypoleucum
- Polygonum multiflorum
- Polygonum hypoleucum
Sources: Wikidata
Taxonomical Classification
This plant belongs to the kingdom Plantae within the phylum Streptophyta and the class Equisetopsida. It is further classified under the subclass Magnoliidae and the order Caryophyllales. Finally, it is a member of the family Polygonaceae and falls under the genus Pleuropterus.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Caryophyllales |
| Family | Polygonaceae |
| Genus | Pleuropterus |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a broad geographical distribution across several distinct regions. In the Caucasus, it can be found specifically within the Transcaucasus area. Its presence in China is widespread, spanning from the North-Central regions to the Southeast. Furthermore, the species is documented in the South-Central parts of China. Finally, its range extends southward to include the island of Hainan.
| Region | Area |
|---|---|
| Caucasus | Transcaucasus |
| China | China South-Central |
| China | Hainan |
| China | China North-Central |
| China | China Southeast |
| Eastern Asia | Japan |
| Eastern Asia | Korea |
| Eastern Asia | Taiwan |
| Indo-China | Thailand |
| Indo-China | Vietnam |
Sources: The World Checklist of Vascular Plants (WCVP)
Plant Parts
Pleuropterus multiflorus has 4 reported plant parts identified across 19 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf, rhizome, stem.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 14 supporting sources | ★★★★★ |
| Leaf | 3 supporting sources | ★★☆☆☆ |
| Rhizome | 1 supporting sources | ★☆☆☆☆ |
| Stem | 1 supporting sources | ★☆☆☆☆ |
Root
- Applied biosciences
- Molecules (Basel, Switzerland)
- Planta medica
- Journal of ethnopharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
View 9 additional sources
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Pharmacognosy magazine
- Frontiers in plant science
- Frontiers of medicine
- The American journal of Chinese medicine
- Heliyon
- Plants (Basel, Switzerland)
- Journal of chromatography. A
- Journal of natural products
Leaf
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Heliyon
- Planta medica
Rhizome
- Oxidative medicine and cellular longevity
Stem
- Planta medica
Chemicals
Pleuropterus multiflorus has 125 reported phytochemicals identified across 19 scientific publications and several other databases. The most consistently reported chemicals include emodin, Physcion, Anthraquinones, Gallic acid, Flavonoids.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| emodin | 19 supporting sources | ★★★★★ |
| Physcion | 11 supporting sources | ★★★★★ |
| Anthraquinones | 7 supporting sources | ★★★★☆ |
| Gallic acid | 5 supporting sources | ★★★☆☆ |
| Flavonoids | 4 supporting sources | ★★☆☆☆ |
| Rhein | 4 supporting sources | ★★☆☆☆ |
| TSG | 4 supporting sources | ★★☆☆☆ |
| ANTHRAQUINONE | 3 supporting sources | ★★☆☆☆ |
| Stilbenes | 3 supporting sources | ★★☆☆☆ |
| ARSENIC | 2 supporting sources | ★☆☆☆☆ |
emodin
- Dr. Duke
- Phytotherapy research : PTR
- Journal of ethnopharmacology
- Planta medica
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
View 14 additional sources
- Frontiers in plant science
- Pharmaceutical biology
- Acta pharmacologica Sinica
- Frontiers in pharmacology
- Journal of acupuncture and meridian studies
- Biological & pharmaceutical bulletin
- Molecules (Basel, Switzerland)
- Protoplasma
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Chemical research in toxicology
- The American journal of Chinese medicine
- Plants (Basel, Switzerland)
- Journal of chromatography. A
Physcion
- Dr. Duke
- Chemical research in toxicology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Frontiers in plant science
- Frontiers in pharmacology
View 6 additional sources
- Biological & pharmaceutical bulletin
- Journal of AOAC International
- Protoplasma
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- The American journal of Chinese medicine
- Journal of ethnopharmacology
Anthraquinones
- Dr. Duke
- Journal of ethnopharmacology
- Journal of pharmaceutical and biomedical analysis
- Scientific data
- Journal of AOAC International
View 2 additional sources
- Protoplasma
- Frontiers in plant science
Gallic acid
- Dr. Duke
- Frontiers in pharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Molecules (Basel, Switzerland)
- Journal of chromatography. A
Flavonoids
- Applied microbiology and biotechnology
- Frontiers in plant science
- Heliyon
- Planta medica
Rhein
- Dr. Duke
- Toxicology letters
- Pharmacognosy magazine
- Journal of chromatography. A
TSG
- Journal of ethnopharmacology
- BioMed research international
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Plants (Basel, Switzerland)
ANTHRAQUINONE
- Journal of ethnopharmacology
- Pharmacognosy magazine
- Journal of acupuncture and meridian studies
Stilbenes
- Applied microbiology and biotechnology
- Frontiers in plant science
- Heliyon
ARSENIC
- Dr. Duke
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Activities
Pleuropterus multiflorus has 454 reported activities identified across 19 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antioxidant, Estrogenic, Hepatoprotective, Antimicrobial.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Anticancer | 5 supporting sources | ★★★☆☆ |
| Antioxidant | 5 supporting sources | ★★★☆☆ |
| Estrogenic | 4 supporting sources | ★★☆☆☆ |
| Hepatoprotective | 4 supporting sources | ★★☆☆☆ |
| Antimicrobial | 3 supporting sources | ★★☆☆☆ |
| Neuroprotective | 3 supporting sources | ★★☆☆☆ |
| Antiinflammatory | 2 supporting sources | ★☆☆☆☆ |
| Antiosteoporotic | 2 supporting sources | ★☆☆☆☆ |
| Antiviral | 2 supporting sources | ★☆☆☆☆ |
| Cardioprotective | 2 supporting sources | ★☆☆☆☆ |
Anticancer
- Dr. Duke
- Phytotherapy research : PTR
- Journal of ethnopharmacology
- International journal of molecular medicine
- Archiv der Pharmazie
Antioxidant
- Dr. Duke
- Phytotherapy research : PTR
- Journal of ethnopharmacology
- Protoplasma
- Neurochemistry international
Estrogenic
- Dr. Duke
- Environmental toxicology and pharmacology
- Journal of ethnopharmacology
- Phytotherapy research : PTR
Hepatoprotective
- Dr. Duke
- Phytotherapy research : PTR
- Scientific data
- Archiv der Pharmazie
Antimicrobial
- Phytotherapy research : PTR
- Journal of ethnopharmacology
- Archiv der Pharmazie
Neuroprotective
- Dr. Duke
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Archiv der Pharmazie
Antiinflammatory
- Dr. Duke
- Phytotherapy research : PTR
Antiosteoporotic
- Dr. Duke
- Journal of ethnopharmacology
Antiviral
- Dr. Duke
- Archiv der Pharmazie
Cardioprotective
- Dr. Duke
- Archiv der Pharmazie
Conditions
Pleuropterus multiflorus has 2 reported investigations on conditions identified across 19 scientific publications and several other databases. The most consistently reported conditions include amnesia, lung cancer.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Amnesia | 1 supporting sources | ★☆☆☆☆ |
| Lung cancer | 1 supporting sources | ★☆☆☆☆ |
Amnesia
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lung cancer
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Preparations
Pleuropterus multiflorus has 44 reported preparations identified across 19 scientific publications and several other databases. The most consistently reported preparations include Polygonum multiflorum extract, hairy roots, 70% EtOH extracts, Fresh (raw) Heshouwu, Heshouwu.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Polygonum multiflorum extract | 2 supporting sources | ★☆☆☆☆ |
| Hairy roots | 2 supporting sources | ★☆☆☆☆ |
| 70% etoh extracts | 1 supporting sources | ★☆☆☆☆ |
| Fresh (raw) heshouwu | 1 supporting sources | ★☆☆☆☆ |
| Heshouwu | 1 supporting sources | ★☆☆☆☆ |
| Meoh extract of the dried root tubers | 1 supporting sources | ★☆☆☆☆ |
| Pmc-12 | 1 supporting sources | ★☆☆☆☆ |
| Pme | 1 supporting sources | ★☆☆☆☆ |
| Rhizome extract | 1 supporting sources | ★☆☆☆☆ |
| Zishen yutai pill | 1 supporting sources | ★☆☆☆☆ |
Polygonum multiflorum extract
- Journal of chromatography. A
- Drug development and industrial pharmacy
Hairy roots
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Pharmacognosy magazine
70% etoh extracts
- Journal of ethnopharmacology
Fresh (raw) heshouwu
- Journal of ethnopharmacology
Heshouwu
- Frontiers of medicine
Meoh extract of the dried root tubers
- Journal of natural products
Pmc-12
- Neuroscience letters
Pme
- Plants (Basel, Switzerland)
Rhizome extract
- Oxidative medicine and cellular longevity
Zishen yutai pill
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica