Fallopia multiflora
Pleuropterus multiflorus · Accepted scientific name
Scientific literature: Very Extensive (760 studies) · ★★★★★
Fallopia multiflora, scientifically known as Pleuropterus multiflorus, is a perennial herb native to East Asia, highly revered in traditional medicine. Commonly called Japanese knotweed, its nutrient-rich rhizomes contain potent compounds like resveratrol, offering significant antioxidant and anti-inflammatory benefits used to support circulation, longevity, and overall metabolic health.
- Family
- Polygonaceae
- Native range
- Asia-Temperate
- Parts used
- Root · Hairy Roots
- Common names
- Not available
- Scientific synonyms
- Reynoutria Multiflora · Fallopia Multiflora · 10 more
Names
Scientific Names
Accepted name
Pleuropterus multiflorusSynonyms
- Reynoutria multiflora
- Fallopia multiflora
- Helxine multiflorum
- Pleuropterus cordatus
- Fallopia multiflora var. hypoleuca
- Bilderdykia multiflora
- Aconogonon hypoleucum
- Reynoutria multiflora var. hypoleuca
- Fagopyrum multiflorum
- Polygonum multiflorum var. hypoleucum
- Polygonum multiflorum
- Polygonum hypoleucum
Taxonomical Classification
This plant belongs to the kingdom Plantae within the phylum Streptophyta and the class Equisetopsida. It is further classified under the subclass Magnoliidae and the order Caryophyllales. Finally, it is a member of the family Polygonaceae and falls under the genus Pleuropterus.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Caryophyllales | WCVP |
| Family | Polygonaceae | WCVP |
| Genus | Pleuropterus | WCVP |
Distribution
This plant exhibits a broad geographical distribution across several distinct regions. In the Caucasus, it can be found specifically within the Transcaucasus area. Its presence in China is widespread, spanning from the North-Central regions to the Southeast. Furthermore, the species is documented in the South-Central parts of China. Finally, its range extends southward to include the island of Hainan.
| Region | Area | Source |
|---|---|---|
| Caucasus | Transcaucasus | WCVP |
| China | China South-Central | WCVP |
| China | Hainan | WCVP |
| China | China North-Central | WCVP |
| China | China Southeast | WCVP |
| Eastern Asia | Japan | WCVP |
| Eastern Asia | Korea | WCVP |
| Eastern Asia | Taiwan | WCVP |
| Indo-China | Thailand | WCVP |
| Indo-China | Vietnam | WCVP |
Plant Parts
This plant, Pleuropterus multiflorus, possesses several distinct morphological features that are utilized in medicinal applications. The plant is characterized by its lush green leaves and can be harvested as whole plants for various preparations. Below the surface, the plant develops a complex root system that includes fine, hairy roots and larger, specialized tuberous roots, which serve as the primary storage organs for its bioactive compounds.| Plant Part | Sources | Confidence |
|---|---|---|
| root | Planta medica (and other 5 sources) | ★★★☆☆ |
| hairy roots | Applied biosciences (and other 4 sources) | ★★☆☆☆ |
| leaves | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 2 sources) | ★☆☆☆☆ |
| Polygonum Multiflorum Radix | BioMed research international (and other 1 sources) | ★☆☆☆☆ |
| Polygonum Multiflorum Radix Preparata | BioMed research international (and other 1 sources) | ★☆☆☆☆ |
| Rhizome | Oxidative medicine and cellular longevity (and other 1 sources) | ★☆☆☆☆ |
| Root tissues | Plants (Basel, Switzerland) (and other 1 sources) | ★☆☆☆☆ |
| adventitious roots | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| bud | Heliyon (and other 1 sources) | ★☆☆☆☆ |
| caulis | Heliyon (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Pleuropterus multiflorus has 125 reported phytochemicals identified across 29 scientific publications and several other databases. The most consistently reported chemicals include emodin, Physcion, Anthraquinones, Gallic acid, Flavonoids.
Most Reported Compounds
| Compound | Sources | Confidence |
|---|---|---|
| emodin | Dr. Duke (and other 19 sources) | ★★★★★ |
| Physcion | Dr. Duke (and other 11 sources) | ★★★★★ |
| Anthraquinones | Dr. Duke (and other 7 sources) | ★★★★☆ |
| Gallic acid | Dr. Duke (and other 5 sources) | ★★★☆☆ |
| Flavonoids | Applied microbiology and biotechnology (and other 4 sources) | ★★☆☆☆ |
| Rhein | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| TSG | Journal of ethnopharmacology (and other 4 sources) | ★★☆☆☆ |
| ANTHRAQUINONE | Journal of ethnopharmacology (and other 3 sources) | ★★☆☆☆ |
| Stilbenes | Applied microbiology and biotechnology (and other 3 sources) | ★★☆☆☆ |
| ARSENIC | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
Activities
Pleuropterus multiflorus has 454 reported activities identified across 29 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antioxidant, Estrogenic, Hepatoprotective, Antimicrobial.
Most Reported Activities
| Activity | Sources | Confidence |
|---|---|---|
| Anticancer | Dr. Duke (and other 5 sources) | ★★★☆☆ |
| Antioxidant | Dr. Duke (and other 5 sources) | ★★★☆☆ |
| Estrogenic | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Hepatoprotective | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Antimicrobial | Phytotherapy research : PTR (and other 3 sources) | ★★☆☆☆ |
| Neuroprotective | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antiinflammatory | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antiosteoporotic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antiviral | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Cardioprotective | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
Medicinal Uses
Pleuropterus multiflorus has 2 reported medicinal uses identified across 29 scientific publications and several other databases. The most consistently reported uses include amnesia, lung cancer.
Most Reported Uses
| Use | Sources | Confidence |
|---|---|---|
| amnesia | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 1 sources) | ★☆☆☆☆ |
| lung cancer | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Confidence |
|---|---|---|
| Polygonum multiflorum extract | Journal of chromatography. A (and other 2 sources) | ★☆☆☆☆ |
| hairy roots | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 2 sources) | ★☆☆☆☆ |
| 70% EtOH extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Fresh (raw) Heshouwu | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Heshouwu | Frontiers of medicine (and other 1 sources) | ★☆☆☆☆ |
| MeOH extract of the dried root tubers | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| PMC-12 | Neuroscience letters (and other 1 sources) | ★☆☆☆☆ |
| PME | Plants (Basel, Switzerland) (and other 1 sources) | ★☆☆☆☆ |
| Rhizome Extract | Oxidative medicine and cellular longevity (and other 1 sources) | ★☆☆☆☆ |
| ZiShen YuTai pill | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |